Medication interaction hub

What Supplements Interact with Delavirdine Mesylate?

Delavirdine Mesylate brand name: Rescriptor. Every interaction below applies to the brands too.

144 Interactions 3 Major 101 Moderate 40 Minor
Curated & coded by · Clinical Pharmacist · Updated October 6, 2026

Drug–supplement interaction data sourced from Natural Medicines Pro, the licensed clinical database from TRC Healthcare / Therapeutic Research, with additional analysis by the HelloPharmacist Pharmacist Team. Our sources · Editorial policy

What is this page for?

One answer, for one medication: what supplements and herbal products interact with Delavirdine Mesylate? Every vitamin, herb, and supplement ingredient we’ve checked against it is on this page, ranked by severity, each linking to the full report for that exact pair.

This page covers supplement interactions only — to check Delavirdine Mesylate against your other medications, use the drug–drug interaction checker. Educational information from our licensed clinical databases, not medical advice. Our editorial policy

HelloPharmacist Bottom Line
Our Pharmacist Explains
What is this? The interaction data in the HelloPharmacist supplement database is licensed from Natural Medicines Pro by TRC Healthcare (Therapeutic Research). HelloPharmacist pharmacists often add our own analysis and context on top of that licensed data — such as this Bottom Line summary and the notes on individual interaction pages — and any such commentary is noted as ours.

St. John's wort is the single entry I'd want anyone on delavirdine (Rescriptor) to understand first. It can pull levels of this HIV medicine down far enough to let the virus rebound and develop resistance to the entire NNRTI class, and that harm doesn't reverse. Grapefruit and activated charcoal also carry major ratings, and a list this long attached to an antiretroviral deserves real caution rather than a quick skim.

Most of the remaining entries share one mechanism. Delavirdine slows the liver enzyme CYP3A4, so it can raise blood levels of well over a hundred herbal ingredients, while a smaller set of inhibitors nudges delavirdine itself higher. Charcoal products and bulky fibers can also trap oral medicines in the gut, so keep them well separated from dosing. Of the 144 ingredients, three rate major, 101 moderate, and 40 minor, and with viral suppression at stake I give the moderates a careful read too.

— , Clinical Pharmacist · July 18, 2026

Major 3 Moderate 101 Minor 40 No known interaction 1,308

This box checks one ingredient at a time (like turmeric or magnesium). Taking a supplement product with a whole label of ingredients? Search the product instead — we check every ingredient on it ↓

Most Viewed Ingredient Interactions

Delavirdine Mesylate: Top Interactions at a Glance

The Delavirdine Mesylate supplement & herbal interactions people checked most in the last 24 hours, colored by severity. Tap any ingredient to open the full report for that pair.

Showing the 12 highest-ranked of 144 interacting ingredients — plus 1,308 more checked with no known interaction. See the complete ranked list.

Start here

The Most-Checked Delavirdine Mesylate Combinations Today

The Delavirdine Mesylate + supplement pages people viewed most in the last 24 hours (resets at midnight). Open any card for the full report.

Moderate Likelihood Possible Vitamin E + Delavirdine Mesylatei

Theoretically, vitamin E might induce metabolism of CYP3A4, possibly reducing the levels CYP3A4 substrates.

Read the full interaction Moderate Likelihood Possible Licorice + Delavirdine Mesylatei

Theoretically, licorice might increase or decrease levels of drugs metabolized by CYP3A4.

Read the full interaction Minor Likelihood Possible Hops + Delavirdine Mesylatei

Theoretically, hops extract might alter metabolism of CYP3A4 substrates; however, this effect may not be clinically significant.

Read the full interaction Moderate Likelihood Possible Dhea + Delavirdine Mesylatei

Theoretically, DHEA might increase the levels of drugs metabolized by CYP3A4.

Read the full interaction Moderate Likelihood Possible Gum Arabic + Delavirdine Mesylatei

Theoretically, gum arabic can alter the absorption of oral drugs due to its fiber content.

Read the full interaction Moderate Likelihood Possible Goji + Delavirdine Mesylatei

Theoretically, goji berry might inhibit CYP3A4 and reduce metabolism of CYP3A4 substrates.

Read the full interaction
The complete list

Every Supplement Checked Against Delavirdine Mesylate

All 1,452 ingredients in our database, ranked by severity — 144 with a Delavirdine Mesylate interaction on file and 1,308 with none found. Filter by severity or search any ingredient; hover the for what each ingredient is.

Looking for an interaction with a specific supplement product? Search products instead ↓

Straight answers

Can You Take It With Delavirdine Mesylate?

One-line answers, one card per combination — scroll through today’s 20 and tap any card for the full report. A different set rotates in daily until every combination has had its turn.

Can you take Vitamin E with Delavirdine Mesylate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, vitamin E might induce metabolism of CYP3A4, possibly reducing the levels CYP3A4 substrates.

Full Vitamin E + Delavirdine Mesylate answer

Can you take Licorice with Delavirdine Mesylate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, licorice might increase or decrease levels of drugs metabolized by CYP3A4.

Full Licorice + Delavirdine Mesylate answer

Can you take Hops with Delavirdine Mesylate?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, hops extract might alter metabolism of CYP3A4 substrates; however, this effect may not be clinically significant.

Full Hops + Delavirdine Mesylate answer

Can you take Dhea with Delavirdine Mesylate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, DHEA might increase the levels of drugs metabolized by CYP3A4.

Full Dhea + Delavirdine Mesylate answer

Can you take Gum Arabic with Delavirdine Mesylate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, gum arabic can alter the absorption of oral drugs due to its fiber content.

Full Gum Arabic + Delavirdine Mesylate answer

Can you take Grapefruit with Delavirdine Mesylate?

Major Use real caution — this is a major-rated interaction, generally best avoided or used only under close supervision. Grapefruit juice can increase levels of drugs metabolized by CYP3A4.

Full Grapefruit + Delavirdine Mesylate answer

Can you take St. John's Wort with Delavirdine Mesylate?

Major Use real caution — this is a major-rated interaction, generally best avoided or used only under close supervision. St.

Full St. John's Wort + Delavirdine Mesylate answer

Can you take Activated Charcoal with Delavirdine Mesylate?

Major Use real caution — this is a major-rated interaction, generally best avoided or used only under close supervision. Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the rout...

Full Activated Charcoal + Delavirdine Mesylate answer

Can you take Cannabidiol (cbd) with Delavirdine Mesylate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Cannabidiol may increase levels of drugs that are metabolized by CYP3A4.

Full Cannabidiol (cbd) + Delavirdine Mesylate answer

Can you take Coffee Charcoal with Delavirdine Mesylate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Coffee charcoal can reduce the absorption of orally administered drugs and should be separated from oral drug administration by at least two...

Full Coffee Charcoal + Delavirdine Mesylate answer

Can you take European Mandrake with Delavirdine Mesylate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concurrent use might increase absorption of some drugs because of inhibited gastrointestinal (GI) motility caused by European...

Full European Mandrake + Delavirdine Mesylate answer

Can you take Glucomannan with Delavirdine Mesylate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, glucomannan may decrease absorption of drugs taken orally.

Full Glucomannan + Delavirdine Mesylate answer

Can you take Guggul with Delavirdine Mesylate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, guggul might reduce the effects of CYP3A4 substrates.

Full Guggul + Delavirdine Mesylate answer

Can you take Schisandra with Delavirdine Mesylate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Schisandra can increase the levels and clinical effects of drugs metabolized by CYP3A4.

Full Schisandra + Delavirdine Mesylate answer

Can you take Tree Turmeric with Delavirdine Mesylate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, tree turmeric might increase the levels and clinical effects of drugs that are substrates of CYP3A4.

Full Tree Turmeric + Delavirdine Mesylate answer

Can you take Acacia Rigidula with Delavirdine Mesylate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, Acacia rigidula products that are adulterated with beta-methylphenylethylamine (BMPEA) might increase the levels of CYP3A4 su...

Full Acacia Rigidula + Delavirdine Mesylate answer

Can you take Adrafinil with Delavirdine Mesylate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, drugs that inhibit CYP3A4 might increase the levels and clinical effects of adrafinil.

Full Adrafinil + Delavirdine Mesylate answer

Can you take African Wild Potato with Delavirdine Mesylate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. In vitro evidence shows that African wild potato extract can inhibit cytochrome P450 3A4 (CYP3A4) enzyme activity by up to 86%.

Full African Wild Potato + Delavirdine Mesylate answer

Can you take American Elder with Delavirdine Mesylate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking American elder might increase levels of CYP3A4 substrates.

Full American Elder + Delavirdine Mesylate answer

Can you take Astaxanthin with Delavirdine Mesylate?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP3A4.

Full Astaxanthin + Delavirdine Mesylate answer
Read the list like a pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each entry links to a full report with the clinical detail, likelihood, evidence level, and citations for that exact combination.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

How Does Our Interaction Checker Work?

Behind every verdict on this page is a category system. Our source database doesn’t document supplement interactions drug-by-drug — it documents them against groups of medications that behave the same way (for example, “drugs processed by the CYP3A4 liver enzyme” or “blood-thinning medications”).

So the check works in three steps: (1) Delavirdine Mesylate is classified into the pharmacology categories it belongs to, (2) every supplement interaction documented against any of those categories is inherited by Delavirdine Mesylate, and (3) each ingredient keeps its own severity, likelihood, and evidence grades from the underlying record. That’s why one supplement can carry several records for one drug — it may interact through more than one category.

Delavirdine Mesylate sits in 6 interaction categories. Open any one to see what the group means:

Cytochrome P450 3A4 (Cyp3A4) Substrates 121 ingredients

A drug-metabolism group: these medications are processed by the named liver enzyme (a cytochrome P450). Supplements that speed this enzyme up or slow it down can lower or raise the medication's levels in your body.

121 of the supplement ingredients on this page reach Delavirdine Mesylate through this category.

Oral Drugs 17 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

17 of the supplement ingredients on this page reach Delavirdine Mesylate through this category.

Cytochrome P450 3A4 (Cyp3A4) Inhibitors 13 ingredients

A drug-metabolism group: these medications are processed by the named liver enzyme (a cytochrome P450). Supplements that speed this enzyme up or slow it down can lower or raise the medication's levels in your body.

13 of the supplement ingredients on this page reach Delavirdine Mesylate through this category.

Cytochrome P450 2C9 (Cyp2C9) Inhibitors 4 ingredients

A drug-metabolism group: these medications are processed by the named liver enzyme (a cytochrome P450). Supplements that speed this enzyme up or slow it down can lower or raise the medication's levels in your body.

4 of the supplement ingredients on this page reach Delavirdine Mesylate through this category.

Cytochrome P450 2C19 (Cyp2C19) Inhibitors 2 ingredients

A drug-metabolism group: these medications are processed by the named liver enzyme (a cytochrome P450). Supplements that speed this enzyme up or slow it down can lower or raise the medication's levels in your body.

2 of the supplement ingredients on this page reach Delavirdine Mesylate through this category.

Non-Nucleoside Reverse Transcriptase Inhibitors (Nnrtis) 1 ingredient

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

1 of the supplement ingredient on this page reaches Delavirdine Mesylate through this category.

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Take a Supplement Product? Check the Whole Bottle Against Delavirdine Mesylate

Most supplements are combination products — and the interaction may come from an ingredient you didn’t buy it for. Search any product below (or scan its label) and we’ll check every ingredient on it against Delavirdine Mesylate.

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Pharmacist Counseling Corner

Delavirdine Mesylate & Supplements: Common Questions

What supplements interact with Delavirdine Mesylate?
Our database currently documents 144 ingredients with a known Delavirdine Mesylate interaction (3 major, 101 moderate, 40 minor). The practical move: scan the major group first, then look up the exact supplements you take rather than reading all 144. The highest-ranked right now: Grapefruit, St. John's Wort, Activated Charcoal.
Which Delavirdine Mesylate supplement interactions are the most serious?
The 3 major-rated combinations — led by Grapefruit, St. John's Wort and Activated Charcoal — deserve real caution: these are the ones generally best avoided, or used only with your prescriber watching. If you take any of them today, don't panic and don't stop anything abruptly — call your pharmacist first. Jump to the ranked list.
Can I take vitamins or supplements while on Delavirdine Mesylate?
Plenty of supplements coexist fine with Delavirdine Mesylate; a shorter list does not. Rather than memorizing it, check the specific ingredients on your labels — the ranked list above covers every one we've checked, and multi-ingredient products can be checked label-by-label with our scanner. Try the label scanner or the interaction checker.
Do brands like Rescriptor have the same supplement interactions as Delavirdine Mesylate?
Yes — Rescriptor all contain Delavirdine Mesylate, so everything on this page applies to them equally. Interactions belong to the active drug, never to the brand on the box; the same is true of generics.
Where do these interaction ratings come from?
Every rating comes from the Natural Medicines database — the same evidence-graded reference pharmacists and hospitals use — and each interaction carries three separate grades: severity (how bad it can be), likelihood (how well it's documented in studies and case reports), and an evidence level. Our pharmacists review the content; we never let an AI decide an interaction. See how to read the ratings and our editorial policy.
What about Delavirdine Mesylate and my other medications?
This page covers Delavirdine Mesylate against supplements and herbal ingredients. Checking Delavirdine Mesylate against your other prescription or OTC medications is a different tool — our drug interaction checker covers that side. Head to the drug–drug interaction checker.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Sourcing

Where This Data Comes From — and Why You Can Trust It

🧪 Licensed clinical database

Every interaction verdict on this page comes from Natural Medicines Pro (TRC Healthcare / Therapeutic Research) — the same evidence-graded reference used by pharmacists and hospitals. We license this data directly; we do not scrape it, and no AI invents an interaction.

🧑‍⚕️ Pharmacist review

This page is curated and coded by , Clinical Pharmacist, with additional analysis by the HelloPharmacist Pharmacist Team. Editorial commentary is ours; the licensed interaction records are shown as sourced.

🔄 Kept current

Our interaction database refreshes on a weekly cycle, and this page re-checks the live database every time it’s rebuilt — what you see reflects the database as of October 6, 2026.

🔍 Full transparency

How every dataset on this site is sourced, licensed, and updated is documented publicly: our data sources · editorial policy · how we use AI.

Educational information, not medical advice. An interaction being on file does not mean it will happen to you — and absence of one is not proof of safety. Never start or stop a medication or supplement without talking to your pharmacist or doctor.