Medication interaction hub

What Supplements Interact with Glyceryl trinitrate?

Glyceryl trinitrate brand name: Nitronal. Every interaction below applies to the brands too.

2 Interactions 2 Major
Curated & coded by · Clinical Pharmacist · Updated September 22, 2026

Drug–supplement interaction data sourced from Natural Medicines Pro, the licensed clinical database from TRC Healthcare / Therapeutic Research, with additional analysis by the HelloPharmacist Pharmacist Team. Our sources · Editorial policy

What is this page for?

One answer, for one medication: what supplements and herbal products interact with Glyceryl trinitrate? Every vitamin, herb, and supplement ingredient we’ve checked against it is on this page, ranked by severity, each linking to the full report for that exact pair.

This page covers supplement interactions only — to check Glyceryl trinitrate against your other medications, use the drug–drug interaction checker. Educational information from our licensed clinical databases, not medical advice. Our editorial policy

HelloPharmacist Bottom Line
Our Pharmacist Explains
What is this? The interaction data in the HelloPharmacist supplement database is licensed from Natural Medicines Pro by TRC Healthcare (Therapeutic Research). HelloPharmacist pharmacists often add our own analysis and context on top of that licensed data — such as this Bottom Line summary and the notes on individual interaction pages — and any such commentary is noted as ours.

The irony with glyceryl trinitrate (Nitronal) is that both supplements known to interact with it, hawthorn and coleus, are sold for heart health, exactly the concern of someone using this angina medicine. Both interactions are rated major, and both work the same way. These botanicals widen blood vessels just as the drug does, so combining them can push coronary vasodilation and blood-pressure lowering further than intended.

Two entries is a short list, but not a mild one. Nitroglycerin is often the tablet or spray someone reaches for when chest pain hits, and its job is opening the heart's own arteries quickly and predictably. Layering a botanical vasodilator on top makes that effect harder to control. Hawthorn in particular turns up in many heart-support blends, so read labels for it by name, and run any similar product past your pharmacist first.

— , Clinical Pharmacist · July 18, 2026

Major 2 No known interaction 1,450

This box checks one ingredient at a time (like turmeric or magnesium). Taking a supplement product with a whole label of ingredients? Search the product instead — we check every ingredient on it ↓

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The Major Interactions to Know About

The most clinically significant Glyceryl trinitrate + supplement combinations in our database, best-documented first. Open any card for the full report.

Major Likelihood Probable Coleus + Glyceryl trinitratei

Theoretically, combining coleus with nitrates might increase the coronary vasodilatory effects.

Read the full interaction Major Likelihood Probable Hawthorn + Glyceryl trinitratei

Theoretically, concomitant use might cause additive coronary vasodilatory effects.

Read the full interaction
The complete list

Every Supplement Checked Against Glyceryl trinitrate

All 1,452 ingredients in our database, ranked by severity — 2 with a Glyceryl trinitrate interaction on file and 1,450 with none found. Filter by severity or search any ingredient; hover the for what each ingredient is.

Looking for an interaction with a specific supplement product? Search products instead ↓

Straight answers

Can You Take It With Glyceryl trinitrate?

One-line answers, one card per combination — scroll through today’s 3 and tap any card for the full report. A different set rotates in daily until every combination has had its turn.

Can you take Coleus with Glyceryl trinitrate?

Major Use real caution — this is a major-rated interaction, generally best avoided or used only under close supervision. Theoretically, combining coleus with nitrates might increase the coronary vasodilatory effects.

Full Coleus + Glyceryl trinitrate answer

Can you take Hawthorn with Glyceryl trinitrate?

Major Use real caution — this is a major-rated interaction, generally best avoided or used only under close supervision. Theoretically, concomitant use might cause additive coronary vasodilatory effects.

Full Hawthorn + Glyceryl trinitrate answer

Can you take Hawthorn with Glyceryl trinitrate?

Major Use real caution — this is a major-rated interaction, generally best avoided or used only under close supervision. Theoretically, concomitant use might cause additive coronary vasodilatory effects.

Full Hawthorn + Glyceryl trinitrate answer
Read the list like a pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each entry links to a full report with the clinical detail, likelihood, evidence level, and citations for that exact combination.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

How Does Our Interaction Checker Work?

Behind every verdict on this page is a category system. Our source database doesn’t document supplement interactions drug-by-drug — it documents them against groups of medications that behave the same way (for example, “drugs processed by the CYP3A4 liver enzyme” or “blood-thinning medications”).

So the check works in three steps: (1) Glyceryl trinitrate is classified into the pharmacology categories it belongs to, (2) every supplement interaction documented against any of those categories is inherited by Glyceryl trinitrate, and (3) each ingredient keeps its own severity, likelihood, and evidence grades from the underlying record. That’s why one supplement can carry several records for one drug — it may interact through more than one category.

Glyceryl trinitrate sits in 1 interaction category. Open any one to see what the group means:

Nitrates 2 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

2 of the supplement ingredients on this page reach Glyceryl trinitrate through this category.

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Take a Supplement Product? Check the Whole Bottle Against Glyceryl trinitrate

Most supplements are combination products — and the interaction may come from an ingredient you didn’t buy it for. Search any product below (or scan its label) and we’ll check every ingredient on it against Glyceryl trinitrate.

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Pharmacist Counseling Corner

Glyceryl trinitrate & Supplements: Common Questions

What supplements interact with Glyceryl trinitrate?
In our interaction database, 2 supplement and herbal ingredients have an interaction with Glyceryl trinitrate on file — 2 rated major, 0 moderate, and 0 minor. That number sounds scarier than it is: severity matters far more than the count, which is why the list on this page is ranked instead of alphabetical. Start at the top. The highest-ranked right now: Coleus, Hawthorn.
Which Glyceryl trinitrate supplement interactions are the most serious?
The 2 major-rated combinations — led by Coleus and Hawthorn — deserve real caution: these are the ones generally best avoided, or used only with your prescriber watching. If you take any of them today, don't panic and don't stop anything abruptly — call your pharmacist first. Jump to the ranked list.
Can I take vitamins or supplements while on Glyceryl trinitrate?
That depends entirely on which supplement. The honest answer for Glyceryl trinitrate is in the ranked list above — and if what you take is a combination product with a dozen ingredients, don't check them one by one: photograph the label with our scanner and we'll check the whole thing at once. Try the label scanner or the interaction checker.
Do brands like Nitronal have the same supplement interactions as Glyceryl trinitrate?
Yes — Nitronal all contain Glyceryl trinitrate, so everything on this page applies to them equally. Interactions belong to the active drug, never to the brand on the box; the same is true of generics.
Where do these interaction ratings come from?
Every rating comes from the Natural Medicines database — the same evidence-graded reference pharmacists and hospitals use — and each interaction carries three separate grades: severity (how bad it can be), likelihood (how well it's documented in studies and case reports), and an evidence level. Our pharmacists review the content; we never let an AI decide an interaction. See how to read the ratings and our editorial policy.
What about Glyceryl trinitrate and my other medications?
This page covers Glyceryl trinitrate against supplements and herbal ingredients. Checking Glyceryl trinitrate against your other prescription or OTC medications is a different tool — our drug interaction checker covers that side. Head to the drug–drug interaction checker.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

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Sourcing

Where This Data Comes From — and Why You Can Trust It

🧪 Licensed clinical database

Every interaction verdict on this page comes from Natural Medicines Pro (TRC Healthcare / Therapeutic Research) — the same evidence-graded reference used by pharmacists and hospitals. We license this data directly; we do not scrape it, and no AI invents an interaction.

🧑‍⚕️ Pharmacist review

This page is curated and coded by , Clinical Pharmacist, with additional analysis by the HelloPharmacist Pharmacist Team. Editorial commentary is ours; the licensed interaction records are shown as sourced.

🔄 Kept current

Our interaction database refreshes on a weekly cycle, and this page re-checks the live database every time it’s rebuilt — what you see reflects the database as of September 22, 2026.

🔍 Full transparency

How every dataset on this site is sourced, licensed, and updated is documented publicly: our data sources · editorial policy · how we use AI.

Educational information, not medical advice. An interaction being on file does not mean it will happen to you — and absence of one is not proof of safety. Never start or stop a medication or supplement without talking to your pharmacist or doctor.