Medication interaction hub

What Supplements Interact with Abametapir?

Abametapir brand name: Xeglyze. Every interaction below applies to the brands too.

22 Interactions 18 Moderate 4 Minor
Curated & coded by · Clinical Pharmacist · Updated September 22, 2026

Drug–supplement interaction data sourced from Natural Medicines Pro, the licensed clinical database from TRC Healthcare / Therapeutic Research, with additional analysis by the HelloPharmacist Pharmacist Team. Our sources · Editorial policy

What is this page for?

One answer, for one medication: what supplements and herbal products interact with Abametapir? Every vitamin, herb, and supplement ingredient we’ve checked against it is on this page, ranked by severity, each linking to the full report for that exact pair.

This page covers supplement interactions only — to check Abametapir against your other medications, use the drug–drug interaction checker. Educational information from our licensed clinical databases, not medical advice. Our editorial policy

HelloPharmacist Bottom Line
Our Pharmacist Explains
What is this? The interaction data in the HelloPharmacist supplement database is licensed from Natural Medicines Pro by TRC Healthcare (Therapeutic Research). HelloPharmacist pharmacists often add our own analysis and context on top of that licensed data — such as this Bottom Line summary and the notes on individual interaction pages — and any such commentary is noted as ours.

Head lice treatments rarely carry interaction lists, but abametapir (Xeglyze) absorbs through the scalp enough to slow two liver enzymes, CYP3A4 and CYP1A2, even after a single use. None of the 22 supplement interactions on record is rated major, so most people can treat this as a heads-up rather than a red flag. The pattern runs opposite to the usual worry. These supplements do not weaken abametapir; instead, it can let them build up, from the caffeine in green tea and similar drinks to CYP3A4-cleared ingredients like cannabis and kratom.

Eighteen entries are moderate and four minor, all resting on theoretical or early evidence rather than confirmed harm in people. Since this is a one-time application, the simplest fix is usually holding the supplement for the window your prescriber advises around treatment. Jitteriness from caffeine or a stronger cannabis effect are the signals worth noticing in the days afterward.

— , Clinical Pharmacist · July 18, 2026

Moderate 18 Minor 4 No known interaction 1,430

This box checks one ingredient at a time (like turmeric or magnesium). Taking a supplement product with a whole label of ingredients? Search the product instead — we check every ingredient on it ↓

Most Viewed Ingredient Interactions

Abametapir: Top Interactions at a Glance

The Abametapir supplement & herbal interactions people checked most in the last 24 hours, colored by severity. Tap any ingredient to open the full report for that pair.

Showing the 12 highest-ranked of 22 interacting ingredients — plus 1,430 more checked with no known interaction. See the complete ranked list.

Start here

The Most-Checked Abametapir Combinations Today

The Abametapir + supplement pages people viewed most in the last 24 hours (resets at midnight). Open any card for the full report.

Minor Likelihood Possible Caffeine + Abametapiri

Theoretically, concomitant use might increase the levels and adverse effects of caffeine.

Read the full interaction Moderate Likelihood Possible Black Tea + Abametapiri

Theoretically, concomitant use might increase the levels and adverse effects of caffeine.

Read the full interaction Moderate Likelihood Possible Green Tea + Abametapiri

Theoretically, concomitant use might increase the levels and adverse effects of caffeine.

Read the full interaction Moderate Likelihood Possible Cannabis + Abametapiri

Theoretically, CYP3A4 inhibitors might increase the levels and adverse effects of cannabis.

Read the full interaction Minor Likelihood Possible Guarana + Abametapiri

Theoretically, concomitant use might increase the levels and adverse effects of caffeine.

Read the full interaction Minor Likelihood Possible Yerba Mate + Abametapiri

Theoretically, concomitant use of CYP1A2 inhibitors and yerba mate might increase levels and adverse effects of the caffeine in yerba mate.

Read the full interaction
The complete list

Every Supplement Checked Against Abametapir

All 1,452 ingredients in our database, ranked by severity — 22 with a Abametapir interaction on file and 1,430 with none found. Filter by severity or search any ingredient; hover the for what each ingredient is.

Looking for an interaction with a specific supplement product? Search products instead ↓

Straight answers

Can You Take It With Abametapir?

One-line answers, one card per combination — scroll through today’s 20 and tap any card for the full report. A different set rotates in daily until every combination has had its turn.

Can you take Caffeine with Abametapir?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, concomitant use might increase the levels and adverse effects of caffeine.

Full Caffeine + Abametapir answer

Can you take Black Tea with Abametapir?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use might increase the levels and adverse effects of caffeine.

Full Black Tea + Abametapir answer

Can you take Green Tea with Abametapir?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use might increase the levels and adverse effects of caffeine.

Full Green Tea + Abametapir answer

Can you take Cannabis with Abametapir?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, CYP3A4 inhibitors might increase the levels and adverse effects of cannabis.

Full Cannabis + Abametapir answer

Can you take Guarana with Abametapir?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, concomitant use might increase the levels and adverse effects of caffeine.

Full Guarana + Abametapir answer

Can you take Ostarine with Abametapir?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, concomitant use of ostarine with CYP3A4 inhibitors could increase the effects and adverse effects of ostarine, although this...

Full Ostarine + Abametapir answer

Can you take Adrafinil with Abametapir?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, drugs that inhibit CYP3A4 might increase the levels and clinical effects of adrafinil.

Full Adrafinil + Abametapir answer

Can you take Cannabidiol (cbd) with Abametapir?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, CYP3A4 inhibitors might increase cannabidiol levels.

Full Cannabidiol (cbd) + Abametapir answer

Can you take Cannabinol (cbn) with Abametapir?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, CYP3A4 inhibitors might increase the levels and clinical effects of cannabinol.

Full Cannabinol (cbn) + Abametapir answer

Can you take Cocoa with Abametapir?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use might increase the levels and adverse effects of caffeine.

Full Cocoa + Abametapir answer

Can you take Cola Nut with Abametapir?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, CYP1A2 inhibitors might increase the levels and adverse effects of the caffeine in cola nut.

Full Cola Nut + Abametapir answer

Can you take Delta-9-tetrahydrocannabinol (thc) with Abametapir?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, CYP3A4 inhibitors might increase the levels and clinical effects of THC.

Full Delta-9-tetrahydrocannabinol (thc) + Abametapir answer

Can you take Ergot with Abametapir?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Ergotamine, a constituent of ergot, is a substrate of cytochrome P450 3A4 (CYP3A4).

Full Ergot + Abametapir answer

Can you take Evodia with Abametapir?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, CYP3A4 inhibitors might increase the levels and clinical effects of evodia.

Full Evodia + Abametapir answer

Can you take Fever Bark with Abametapir?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, CYP3A4 inhibitors might increase the levels and clinical effects of yohimbine, a constituent of fever bark.

Full Fever Bark + Abametapir answer

Can you take Kratom with Abametapir?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. CYP3A4 inhibitors might increase the concentrations and clinical effects of kratom's primary active alkaloid mitragynine.

Full Kratom + Abametapir answer

Can you take Oolong Tea with Abametapir?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use might increase the levels and adverse effects of the caffeine in oolong tea.

Full Oolong Tea + Abametapir answer

Can you take Pu-erh Tea with Abametapir?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use might increase the levels and adverse effects of caffeine.

Full Pu-erh Tea + Abametapir answer

Can you take Red Yeast Rice with Abametapir?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, drugs that inhibit the CYP3A4 enzymes might increase levels of lovastatin from red yeast rice.

Full Red Yeast Rice + Abametapir answer

Can you take Thunder God Vine with Abametapir?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, CYP3A4 inhibitors might increase the levels and adverse effects of thunder god vine constituents.

Full Thunder God Vine + Abametapir answer
Read the list like a pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each entry links to a full report with the clinical detail, likelihood, evidence level, and citations for that exact combination.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

How Does Our Interaction Checker Work?

Behind every verdict on this page is a category system. Our source database doesn’t document supplement interactions drug-by-drug — it documents them against groups of medications that behave the same way (for example, “drugs processed by the CYP3A4 liver enzyme” or “blood-thinning medications”).

So the check works in three steps: (1) Abametapir is classified into the pharmacology categories it belongs to, (2) every supplement interaction documented against any of those categories is inherited by Abametapir, and (3) each ingredient keeps its own severity, likelihood, and evidence grades from the underlying record. That’s why one supplement can carry several records for one drug — it may interact through more than one category.

Abametapir sits in 2 interaction categories. Open any one to see what the group means:

Cytochrome P450 3A4 (Cyp3A4) Inhibitors 13 ingredients

A drug-metabolism group: these medications are processed by the named liver enzyme (a cytochrome P450). Supplements that speed this enzyme up or slow it down can lower or raise the medication's levels in your body.

13 of the supplement ingredients on this page reach Abametapir through this category.

Cytochrome P450 1A2 (Cyp1A2) Inhibitors 10 ingredients

A drug-metabolism group: these medications are processed by the named liver enzyme (a cytochrome P450). Supplements that speed this enzyme up or slow it down can lower or raise the medication's levels in your body.

10 of the supplement ingredients on this page reach Abametapir through this category.

Check a real product

Take a Supplement Product? Check the Whole Bottle Against Abametapir

Most supplements are combination products — and the interaction may come from an ingredient you didn’t buy it for. Search any product below (or scan its label) and we’ll check every ingredient on it against Abametapir.

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Pharmacist Counseling Corner

Abametapir & Supplements: Common Questions

What supplements interact with Abametapir?
More than you might expect — 22 in total, though they are far from equal: 0 are rated major, 18 moderate, and 4 minor. The ranked list on this page puts the ones that genuinely matter first, and every entry opens a full report on that exact pair. The highest-ranked right now: Adrafinil, Black Tea, Cannabidiol (cbd).
Which Abametapir supplement interactions are the most serious?
None of the Abametapir supplement interactions on file are currently rated major. The most significant are the 18 moderate-rated ones — combinations that may need monitoring, a dose adjustment, or separated timing. Still worth a quick look through the ranked list for anything you take daily. Jump to the ranked list.
Can I take vitamins or supplements while on Abametapir?
Usually yes — most people on Abametapir can take most supplements. The catch is the exceptions, and they aren't always the exotic ones (St. John's Wort trips up more prescriptions than almost anything sold next to it). Look up each ingredient you actually take in the list above, and treat "no known interaction" as a green-ish light, not a guarantee. Try the label scanner or the interaction checker.
Do brands like Xeglyze have the same supplement interactions as Abametapir?
Yes — Xeglyze all contain Abametapir, so everything on this page applies to them equally. Interactions belong to the active drug, never to the brand on the box; the same is true of generics.
Where do these interaction ratings come from?
Every rating comes from the Natural Medicines database — the same evidence-graded reference pharmacists and hospitals use — and each interaction carries three separate grades: severity (how bad it can be), likelihood (how well it's documented in studies and case reports), and an evidence level. Our pharmacists review the content; we never let an AI decide an interaction. See how to read the ratings and our editorial policy.
What about Abametapir and my other medications?
This page covers Abametapir against supplements and herbal ingredients. Checking Abametapir against your other prescription or OTC medications is a different tool — our drug interaction checker covers that side. Head to the drug–drug interaction checker.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

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Sourcing

Where This Data Comes From — and Why You Can Trust It

🧪 Licensed clinical database

Every interaction verdict on this page comes from Natural Medicines Pro (TRC Healthcare / Therapeutic Research) — the same evidence-graded reference used by pharmacists and hospitals. We license this data directly; we do not scrape it, and no AI invents an interaction.

🧑‍⚕️ Pharmacist review

This page is curated and coded by , Clinical Pharmacist, with additional analysis by the HelloPharmacist Pharmacist Team. Editorial commentary is ours; the licensed interaction records are shown as sourced.

🔄 Kept current

Our interaction database refreshes on a weekly cycle, and this page re-checks the live database every time it’s rebuilt — what you see reflects the database as of September 22, 2026.

🔍 Full transparency

How every dataset on this site is sourced, licensed, and updated is documented publicly: our data sources · editorial policy · how we use AI.

Educational information, not medical advice. An interaction being on file does not mean it will happen to you — and absence of one is not proof of safety. Never start or stop a medication or supplement without talking to your pharmacist or doctor.