Medication interaction hub

What Supplements Interact with Iodine (topical)?

Iodine (topical) brand name: Iodine Tincture. Every interaction below applies to the brands too.

6 Interactions 2 Moderate 4 Minor
Curated & coded by · Clinical Pharmacist · Updated September 23, 2026

Drug–supplement interaction data sourced from Natural Medicines Pro, the licensed clinical database from TRC Healthcare / Therapeutic Research, with additional analysis by the HelloPharmacist Pharmacist Team. Our sources · Editorial policy

What is this page for?

One answer, for one medication: what supplements and herbal products interact with Iodine (topical)? Every vitamin, herb, and supplement ingredient we’ve checked against it is on this page, ranked by severity, each linking to the full report for that exact pair.

This page covers supplement interactions only — to check Iodine (topical) against your other medications, use the drug–drug interaction checker. Educational information from our licensed clinical databases, not medical advice. Our editorial policy

HelloPharmacist Bottom Line
Our Pharmacist Explains
What is this? The interaction data in the HelloPharmacist supplement database is licensed from Natural Medicines Pro by TRC Healthcare (Therapeutic Research). HelloPharmacist pharmacists often add our own analysis and context on top of that licensed data — such as this Bottom Line summary and the notes on individual interaction pages — and any such commentary is noted as ours.

Iodine tincture is the brown antiseptic people still dab on cuts and scrapes, and its supplement interaction list is short and mostly mild. Of the six ingredients on file, none is rated major, two are moderate, and four are minor. The moderate pair, DMSO and turpentine oil, share the same concern when used near the same patch of skin. Both may pull topical medicines deeper through the skin, so iodine's effect, and its sting, could turn out stronger than you expected.

Most of the minor entries run the other direction, with iodine's germ-killing nature working against the supplement rather than against you. Brewer's yeast and Saccharomyces boulardii probiotics are live organisms, and an antifungal can kill enough of them to blunt whatever benefit you were after, so spacing the two well apart is the simple fix. For most people this pairing list is entirely workable; its value is knowing which few combinations deserve a second look.

— , Clinical Pharmacist · July 18, 2026

Moderate 2 Minor 4 No known interaction 1,446

This box checks one ingredient at a time (like turmeric or magnesium). Taking a supplement product with a whole label of ingredients? Search the product instead — we check every ingredient on it ↓

Top Ingredient Interactions

Iodine (topical): Top Interactions at a Glance

The most significant Iodine (topical) supplement & herbal interactions, colored by severity. Tap any ingredient to open the full report for that pair.

Showing the 6 highest-ranked of 6 interacting ingredients — plus 1,446 more checked with no known interaction. See the complete ranked list.

Start here

The Moderate Interactions to Know About

The most clinically significant Iodine (topical) + supplement combinations in our database, best-documented first. Open any card for the full report.

Moderate Likelihood Possible Dimethylsulfoxide (dmso) + Iodine (topical)i

Topical DMSO might increase the effects and adverse effects of topical drugs.

Read the full interaction Moderate Likelihood Possible Turpentine Oil + Iodine (topical)i

Some in vitro research shows that alpha-pinene, the major constituent of turpentine oil, does not increase the absorption of chlorpromazine or haloperidol when...

Read the full interaction
The complete list

Every Supplement Checked Against Iodine (topical)

All 1,452 ingredients in our database, ranked by severity — 6 with a Iodine (topical) interaction on file and 1,446 with none found. Filter by severity or search any ingredient; hover the for what each ingredient is.

Looking for an interaction with a specific supplement product? Search products instead ↓

Straight answers

Can You Take It With Iodine (topical)?

One-line answers, one card per combination — scroll through today’s 11 and tap any card for the full report. A different set rotates in daily until every combination has had its turn.

Can you take Brewer's Yeast with Iodine (topical)?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, taking antifungals with some brewer's yeast products might decrease the effectiveness of brewer's yeast.

Full Brewer's Yeast + Iodine (topical) answer

Can you take Dimethylsulfoxide (dmso) with Iodine (topical)?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Topical DMSO might increase the effects and adverse effects of topical drugs.

Full Dimethylsulfoxide (dmso) + Iodine (topical) answer

Can you take Turpentine Oil with Iodine (topical)?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Some in vitro research shows that alpha-pinene, the major constituent of turpentine oil, does not increase the absorption of chlorpromazine...

Full Turpentine Oil + Iodine (topical) answer

Can you take Alchemilla with Iodine (topical)?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. While no side effects have been reported from orally using Alchemilla, a clinical study titled "Treatment of Aphthous Stomatitis with Topica...

Full Alchemilla + Iodine (topical) answer

Can you take Probiotics with Iodine (topical)?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, taking antifungals with certain probiotics might decrease the effectiveness of probiotics.

Full Probiotics + Iodine (topical) answer

Can you take Saccharomyces Boulardii with Iodine (topical)?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, taking antifungals with Saccharomyces boulardii might decrease the effectiveness of Saccharomyces boulardii.

Full Saccharomyces Boulardii + Iodine (topical) answer

Can you take Dimethylsulfoxide (dmso) with Iodine (topical)?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Topical DMSO might increase the effects and adverse effects of topical drugs.

Full Dimethylsulfoxide (dmso) + Iodine (topical) answer

Can you take Turpentine Oil with Iodine (topical)?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Some in vitro research shows that alpha-pinene, the major constituent of turpentine oil, does not increase the absorption of chlorpromazine...

Full Turpentine Oil + Iodine (topical) answer

Can you take Alchemilla with Iodine (topical)?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. While no side effects have been reported from orally using Alchemilla, a clinical study titled "Treatment of Aphthous Stomatitis with Topica...

Full Alchemilla + Iodine (topical) answer

Can you take Probiotics with Iodine (topical)?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, taking antifungals with certain probiotics might decrease the effectiveness of probiotics.

Full Probiotics + Iodine (topical) answer

Can you take Saccharomyces Boulardii with Iodine (topical)?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, taking antifungals with Saccharomyces boulardii might decrease the effectiveness of Saccharomyces boulardii.

Full Saccharomyces Boulardii + Iodine (topical) answer
Read the list like a pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each entry links to a full report with the clinical detail, likelihood, evidence level, and citations for that exact combination.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

How Does Our Interaction Checker Work?

Behind every verdict on this page is a category system. Our source database doesn’t document supplement interactions drug-by-drug — it documents them against groups of medications that behave the same way (for example, “drugs processed by the CYP3A4 liver enzyme” or “blood-thinning medications”).

So the check works in three steps: (1) Iodine (topical) is classified into the pharmacology categories it belongs to, (2) every supplement interaction documented against any of those categories is inherited by Iodine (topical), and (3) each ingredient keeps its own severity, likelihood, and evidence grades from the underlying record. That’s why one supplement can carry several records for one drug — it may interact through more than one category.

Iodine (topical) sits in 2 interaction categories. Open any one to see what the group means:

Antifungals 3 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

3 of the supplement ingredients on this page reach Iodine (topical) through this category.

Topical Drugs 3 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

3 of the supplement ingredients on this page reach Iodine (topical) through this category.

Check a real product

Take a Supplement Product? Check the Whole Bottle Against Iodine (topical)

Most supplements are combination products — and the interaction may come from an ingredient you didn’t buy it for. Search any product below (or scan its label) and we’ll check every ingredient on it against Iodine (topical).

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Pharmacist Counseling Corner

Iodine (topical) & Supplements: Common Questions

What supplements interact with Iodine (topical)?
More than you might expect — 6 in total, though they are far from equal: 0 are rated major, 2 moderate, and 4 minor. The ranked list on this page puts the ones that genuinely matter first, and every entry opens a full report on that exact pair. The highest-ranked right now: Dimethylsulfoxide (dmso), Turpentine Oil, Alchemilla.
Which Iodine (topical) supplement interactions are the most serious?
None of the Iodine (topical) supplement interactions on file are currently rated major. The most significant are the 2 moderate-rated ones — combinations that may need monitoring, a dose adjustment, or separated timing. Still worth a quick look through the ranked list for anything you take daily. Jump to the ranked list.
Can I take vitamins or supplements while on Iodine (topical)?
Usually yes — most people on Iodine (topical) can take most supplements. The catch is the exceptions, and they aren't always the exotic ones (St. John's Wort trips up more prescriptions than almost anything sold next to it). Look up each ingredient you actually take in the list above, and treat "no known interaction" as a green-ish light, not a guarantee. Try the label scanner or the interaction checker.
Do brands like Iodine Tincture have the same supplement interactions as Iodine (topical)?
Yes — Iodine Tincture all contain Iodine (topical), so everything on this page applies to them equally. Interactions belong to the active drug, never to the brand on the box; the same is true of generics.
Where do these interaction ratings come from?
Every rating comes from the Natural Medicines database — the same evidence-graded reference pharmacists and hospitals use — and each interaction carries three separate grades: severity (how bad it can be), likelihood (how well it's documented in studies and case reports), and an evidence level. Our pharmacists review the content; we never let an AI decide an interaction. See how to read the ratings and our editorial policy.
What about Iodine (topical) and my other medications?
This page covers Iodine (topical) against supplements and herbal ingredients. Checking Iodine (topical) against your other prescription or OTC medications is a different tool — our drug interaction checker covers that side. Head to the drug–drug interaction checker.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Sourcing

Where This Data Comes From — and Why You Can Trust It

🧪 Licensed clinical database

Every interaction verdict on this page comes from Natural Medicines Pro (TRC Healthcare / Therapeutic Research) — the same evidence-graded reference used by pharmacists and hospitals. We license this data directly; we do not scrape it, and no AI invents an interaction.

🧑‍⚕️ Pharmacist review

This page is curated and coded by , Clinical Pharmacist, with additional analysis by the HelloPharmacist Pharmacist Team. Editorial commentary is ours; the licensed interaction records are shown as sourced.

🔄 Kept current

Our interaction database refreshes on a weekly cycle, and this page re-checks the live database every time it’s rebuilt — what you see reflects the database as of September 23, 2026.

🔍 Full transparency

How every dataset on this site is sourced, licensed, and updated is documented publicly: our data sources · editorial policy · how we use AI.

Educational information, not medical advice. An interaction being on file does not mean it will happen to you — and absence of one is not proof of safety. Never start or stop a medication or supplement without talking to your pharmacist or doctor.