What Supplements Interact with Somatrogon-ghla?
Somatrogon-ghla brand name: Ngenla. Every interaction below applies to the brands too.
Drug–supplement interaction data sourced from Natural Medicines Pro, the licensed clinical database from TRC Healthcare / Therapeutic Research, with additional analysis by the HelloPharmacist Pharmacist Team. Our sources · Editorial policy
What is this page for?
One answer, for one medication: what supplements and herbal products interact with Somatrogon-ghla? Every vitamin, herb, and supplement ingredient we’ve checked against it is on this page, ranked by severity, each linking to the full report for that exact pair.
This page covers supplement interactions only — to check Somatrogon-ghla against your other medications, use the drug–drug interaction checker. Educational information from our licensed clinical databases, not medical advice. Our editorial policy
19 supplements and herbal ingredients have interactions with Somatrogon-ghla on file in the HelloPharmacist interaction database — 0 rated major, 19 moderate, and 0 minor. The most serious involve Alkanna, Alpine Ragwort, Boneset, Borage and Butterbur.
Our assessment: none of these currently rise to the major tier, so for most people supplements are generally workable alongside Somatrogon-ghla — the value of this page is knowing which combinations to watch, not avoiding supplements altogether.
Ranked by severity below. Every entry links to the full pharmacist-reviewed report for that exact combination — what can happen, how likely it is, and what to do about it.
This box checks one ingredient at a time (like turmeric or magnesium). Taking a supplement product with a whole label of ingredients? Search the product instead — we check every ingredient on it ↓
Somatrogon-ghla: Top Interactions at a Glance
The most significant Somatrogon-ghla supplement & herbal interactions, colored by severity. Tap any ingredient to open the full report for that pair.
Showing the 12 highest-ranked of 19 interacting ingredients — plus 1,433 more checked with no known interaction. See the complete ranked list.
The Moderate Interactions to Know About
The most clinically significant Somatrogon-ghla + supplement combinations in our database, best-documented first. Open any card for the full report.
Hepatotoxic pyrrolizidine alkaloids (PAs) are substrates of cytochrome P450 3A4 (CYP3A4).
Read the full interaction Moderate Likelihood Possible Alpine Ragwort + Somatrogon-ghlaiTheoretically, CYP3A4 inducers might increase the risk of adverse effects from the pyrrolizidine alkaloid (PA) constituents in alpine ragwort.
Read the full interaction Moderate Likelihood Possible Boneset + Somatrogon-ghlaiBoneset belongs to the genus Eupatorium, and many species of this genus contain hepatotoxic pyrrolizidine alkaloids (PAs).
Read the full interaction Moderate Likelihood Possible Borage + Somatrogon-ghlaiTheoretically, taking borage with drugs that induce CYP3A4 might increase levels of pyrrolizidine alkaloid (PA) toxic metabolites.
Read the full interaction Moderate Likelihood Possible Butterbur + Somatrogon-ghlaiTheoretically, CYP3A4 inducers might increase the toxicity of butterbur.
Read the full interaction Moderate Likelihood Possible Cannabidiol (cbd) + Somatrogon-ghlaiTheoretically, CYP3A4 inducers might decrease cannabidiol levels.
Read the full interactionEvery Supplement Checked Against Somatrogon-ghla
All 1,452 ingredients in our database, ranked by severity — 19 with a Somatrogon-ghla interaction on file and 1,433 with none found. Filter by severity or search any ingredient; hover the for what each ingredient is.
Looking for an interaction with a specific supplement product? Search products instead ↓
No ingredients match “”.
AlkannaAlkanna Tinctoria, alkanet, alkanna Radix, +9 more Possible
What it is: Alkanna is a Mediterranean plant whose red root has long been used as a dye and as a folk skin remedy for wounds and burns.
Hepatotoxic pyrrolizidine alkaloids (PAs) are substrates of cytochrome P450 3A4 (CYP3A4).
Read the full Alkanna + Somatrogon-ghla interactionAlpine RagwortSenecio Nemorensis, ragwort, senecio Herb Possible
What it is: Alpine Ragwort is a wild plant in the daisy family that contains pyrrolizidine alkaloids (PAs), which can severely damage the liver.
Theoretically, CYP3A4 inducers might increase the risk of adverse effects from the pyrrolizidine alkaloid (PA) constituents in alpine ragwort.
Read the full Alpine Ragwort + Somatrogon-ghla interactionBoneset Possible
What it is: Boneset is a traditional North American herb long used in teas for fevers, colds, and flu, but modern human studies are very limited.
Boneset belongs to the genus Eupatorium, and many species of this genus contain hepatotoxic pyrrolizidine alkaloids (PAs).
Read the full Boneset + Somatrogon-ghla interactionBorageBee Plant, beebread, borage Oil, +12 more Possible
What it is: Borage is a Mediterranean herb whose seed oil is rich in gamma-linolenic acid (GLA), an omega-6 fatty acid studied mostly for skin condition...
Theoretically, taking borage with drugs that induce CYP3A4 might increase levels of pyrrolizidine alkaloid (PA) toxic metabolites.
Read the full Borage + Somatrogon-ghla interactionButterbur Possible
What it is: Butterbur is a plant extract most studied for preventing migraines and easing hay fever symptoms, and some standardized products show promis...
Theoretically, CYP3A4 inducers might increase the toxicity of butterbur.
Read the full Butterbur + Somatrogon-ghla interactionCannabidiol (cbd) Possible
What it is: CBD is a compound from the cannabis (hemp) plant that does not cause a 'high.' It has strong evidence only for certain rare seizure disorder...
Theoretically, CYP3A4 inducers might decrease cannabidiol levels.
Read the full Cannabidiol (cbd) + Somatrogon-ghla interactionCannabisCannabis Sativa, anashca, banji, +25 more Possible
What it is: Cannabis contains many active compounds, mainly THC (which causes a 'high') and CBD (which does not).
Theoretically, CYP3A4 inducers might reduce the levels and clinical effects of cannabis.
Read the full Cannabis + Somatrogon-ghla interactionColtsfootTussilago Farfara, ass's Foot, brandlattich, +17 more Possible
What it is: Coltsfoot is a traditional herb long used to soothe coughs and clear mucus, but solid human evidence for these uses is lacking.
Hepatotoxic pyrrolizidine alkaloids (PA) are substrates of cytochrome P450 3A4 (CYP3A4).
Read the full Coltsfoot + Somatrogon-ghla interactionComfreySymphytum Officinale, ass Ear, beinwellwurzel, +15 more Possible
What it is: Comfrey is a traditional herb used mainly on the skin for bruises, sprains, and joint pain, and some topical products show modest benefit fo...
Theoretically, CYP3A4 inducers might increase the risk of adverse effects from the pyrrolizidine alkaloid constituents in comfrey.
Read the full Comfrey + Somatrogon-ghla interactionDelta-9-tetrahydrocannabinol (thc)Bho, black Glass, budder, +9 more Possible
What it is: THC is the main mind-altering compound in cannabis and is best known for causing a 'high.' A prescription form (dronabinol) is approved for...
Theoretically, CYP3A4 inducers might reduce the levels and clinical effects of THC.
Read the full Delta-9-tetrahydrocannabinol (thc) + Somatrogon-ghla interactionDusty Miller Possible
What it is: Dusty Miller is a silvery ornamental plant that has been used in folk medicine, mainly as an eye remedy for cataracts and irritation.
Theoretically, CYP3A4 inducers might increase the risk of adverse effects from the pyrrolizidine alkaloid (PA) constituents in dusty miller.
Read the full Dusty Miller + Somatrogon-ghla interactionEvodia Possible
What it is: Evodia is a fruit used in traditional Chinese medicine, most often for digestive complaints, headaches, and menstrual pain.
Theoretically, taking CYP3A4 inducers might decrease the levels and clinical effects of evodia.
Read the full Evodia + Somatrogon-ghla interactionGolden Ragwort Possible
What it is: Golden Ragwort is a flowering plant once used in traditional and folk medicine, mainly for menstrual and female reproductive complaints.
Theoretically, CYP3A4 inducers might increase the risk of adverse effects from the pyrrolizidine alkaloid (PA) constituents in golden ragwort.
Read the full Golden Ragwort + Somatrogon-ghla interactionGravel Root Possible
What it is: Gravel Root is a traditional North American herb long used by herbalists for kidney stones and urinary problems, but there is very little mo...
Hepatotoxic pyrrolizidine alkaloids (PA) are substrates of cytochrome P450 3A4 (CYP3A4).
Read the full Gravel Root + Somatrogon-ghla interactionGroundsel Possible
What it is: Groundsel is a common weed traditionally used as a folk remedy, but it contains pyrrolizidine alkaloids that can cause serious liver damage.
Theoretically, taking CYP3A4 inducers with groundsel might increase the risk of pyrrolizidine alkaloid toxicity, such as hepatotoxicity.
Read the full Groundsel + Somatrogon-ghla interactionHemp AgrimonyEupatorium Cannabinum, alpenkraut, cañamazo, +15 more Possible
What it is: Hemp agrimony is a traditional European herb that has been used for digestion, colds, and as a general tonic, but there is very little relia...
Hemp agrimony contains hepatotoxic pyrrolizidine alkaloids (PA) which are substrates of cytochrome P450 3A4 (CYP3A4).
Read the full Hemp Agrimony + Somatrogon-ghla interactionHound's Tongue Possible
What it is: Hound's Tongue is a traditional folk remedy used mostly on the skin and for coughs, but there is little to no reliable human research showin...
Theoretically, CYP3A4 inducers can increase the toxicity of the pyrrolizidine alkaloid (PA) constituents of hound's tongue.
Read the full Hound's Tongue + Somatrogon-ghla interactionOstarine Possible
What it is: Ostarine (also called MK-2866 or enobosarm) is an experimental, unapproved drug known as a SARM (selective androgen receptor modulator), not...
Theoretically, concomitant use of ostarine with CYP3A4 inducers could decrease the clinical effects of ostarine.
Read the full Ostarine + Somatrogon-ghla interactionTansy Ragwort Possible
What it is: Tansy ragwort is a toxic weed that contains pyrrolizidine alkaloids, which can seriously damage the liver.
Theoretically, CYP3A4 inducers might increase the risk of adverse effects from the pyrrolizidine alkaloid (PA) constituents in tansy ragwort.
Read the full Tansy Ragwort + Somatrogon-ghla interactionCan You Take It With Somatrogon-ghla?
One-line answers, one card per combination — scroll through today’s 20 and tap any card for the full report. A different set rotates in daily until every combination has had its turn.
Can you take Dusty Miller with Somatrogon-ghla?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, CYP3A4 inducers might increase the risk of adverse effects from the pyrrolizidine alkaloid (PA) constituents in dusty miller.
Full Dusty Miller + Somatrogon-ghla answerCan you take Evodia with Somatrogon-ghla?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking CYP3A4 inducers might decrease the levels and clinical effects of evodia.
Full Evodia + Somatrogon-ghla answerCan you take Golden Ragwort with Somatrogon-ghla?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, CYP3A4 inducers might increase the risk of adverse effects from the pyrrolizidine alkaloid (PA) constituents in golden ragwor...
Full Golden Ragwort + Somatrogon-ghla answerCan you take Gravel Root with Somatrogon-ghla?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Hepatotoxic pyrrolizidine alkaloids (PA) are substrates of cytochrome P450 3A4 (CYP3A4).
Full Gravel Root + Somatrogon-ghla answerCan you take Groundsel with Somatrogon-ghla?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking CYP3A4 inducers with groundsel might increase the risk of pyrrolizidine alkaloid toxicity, such as hepatotoxicity.
Full Groundsel + Somatrogon-ghla answerCan you take Hemp Agrimony with Somatrogon-ghla?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Hemp agrimony contains hepatotoxic pyrrolizidine alkaloids (PA) which are substrates of cytochrome P450 3A4 (CYP3A4).
Full Hemp Agrimony + Somatrogon-ghla answerCan you take Hound's Tongue with Somatrogon-ghla?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, CYP3A4 inducers can increase the toxicity of the pyrrolizidine alkaloid (PA) constituents of hound's tongue.
Full Hound's Tongue + Somatrogon-ghla answerCan you take Ostarine with Somatrogon-ghla?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use of ostarine with CYP3A4 inducers could decrease the clinical effects of ostarine.
Full Ostarine + Somatrogon-ghla answerCan you take Tansy Ragwort with Somatrogon-ghla?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, CYP3A4 inducers might increase the risk of adverse effects from the pyrrolizidine alkaloid (PA) constituents in tansy ragwort...
Full Tansy Ragwort + Somatrogon-ghla answerCan you take Alkanna with Somatrogon-ghla?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Hepatotoxic pyrrolizidine alkaloids (PAs) are substrates of cytochrome P450 3A4 (CYP3A4).
Full Alkanna + Somatrogon-ghla answerCan you take Alpine Ragwort with Somatrogon-ghla?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, CYP3A4 inducers might increase the risk of adverse effects from the pyrrolizidine alkaloid (PA) constituents in alpine ragwor...
Full Alpine Ragwort + Somatrogon-ghla answerCan you take Boneset with Somatrogon-ghla?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Boneset belongs to the genus Eupatorium, and many species of this genus contain hepatotoxic pyrrolizidine alkaloids (PAs).
Full Boneset + Somatrogon-ghla answerCan you take Borage with Somatrogon-ghla?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking borage with drugs that induce CYP3A4 might increase levels of pyrrolizidine alkaloid (PA) toxic metabolites.
Full Borage + Somatrogon-ghla answerCan you take Butterbur with Somatrogon-ghla?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, CYP3A4 inducers might increase the toxicity of butterbur.
Full Butterbur + Somatrogon-ghla answerCan you take Cannabidiol (cbd) with Somatrogon-ghla?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, CYP3A4 inducers might decrease cannabidiol levels.
Full Cannabidiol (cbd) + Somatrogon-ghla answerCan you take Cannabis with Somatrogon-ghla?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, CYP3A4 inducers might reduce the levels and clinical effects of cannabis.
Full Cannabis + Somatrogon-ghla answerCan you take Coltsfoot with Somatrogon-ghla?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Hepatotoxic pyrrolizidine alkaloids (PA) are substrates of cytochrome P450 3A4 (CYP3A4).
Full Coltsfoot + Somatrogon-ghla answerCan you take Comfrey with Somatrogon-ghla?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, CYP3A4 inducers might increase the risk of adverse effects from the pyrrolizidine alkaloid constituents in comfrey.
Full Comfrey + Somatrogon-ghla answerCan you take Delta-9-tetrahydrocannabinol (thc) with Somatrogon-ghla?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, CYP3A4 inducers might reduce the levels and clinical effects of THC.
Full Delta-9-tetrahydrocannabinol (thc) + Somatrogon-ghla answerCan you take Dusty Miller with Somatrogon-ghla?
Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, CYP3A4 inducers might increase the risk of adverse effects from the pyrrolizidine alkaloid (PA) constituents in dusty miller.
Full Dusty Miller + Somatrogon-ghla answerWhat Severity, Likelihood & Evidence Mean
Severity — How Serious It Can Be
- Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
- Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
- Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
- No known interaction. Checked against our sources with nothing documented — not the same as proven safety.
Likelihood — How Well It’s Documented
- Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
- Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
- Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
- Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.
Where This Data Comes From
- Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
- Each entry links to a full report with the clinical detail, likelihood, evidence level, and citations for that exact combination.
- Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.
How Does Our Interaction Checker Work?
Behind every verdict on this page is a category system. Our source database doesn’t document supplement interactions drug-by-drug — it documents them against groups of medications that behave the same way (for example, “drugs processed by the CYP3A4 liver enzyme” or “blood-thinning medications”).
So the check works in three steps: (1) Somatrogon-ghla is classified into the pharmacology categories it belongs to, (2) every supplement interaction documented against any of those categories is inherited by Somatrogon-ghla, and (3) each ingredient keeps its own severity, likelihood, and evidence grades from the underlying record. That’s why one supplement can carry several records for one drug — it may interact through more than one category.
Somatrogon-ghla sits in 1 interaction category. Open any one to see what the group means:
Cytochrome P450 3A4 (Cyp3A4) Inducers 19 ingredients
A drug-metabolism group: these medications are processed by the named liver enzyme (a cytochrome P450). Supplements that speed this enzyme up or slow it down can lower or raise the medication's levels in your body.
19 of the supplement ingredients on this page reach Somatrogon-ghla through this category.
Take a Supplement Product? Check the Whole Bottle Against Somatrogon-ghla
Most supplements are combination products — and the interaction may come from an ingredient you didn’t buy it for. Search any product below (or scan its label) and we’ll check every ingredient on it against Somatrogon-ghla.
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Products that contain Somatrogon-ghla-interacting ingredients
Real supplements from the NIH label database that contain the top interacting ingredients on this page — each one is worth a full label check before combining with Somatrogon-ghla.
Somatrogon-ghla & Supplements: Common Questions
What supplements interact with Somatrogon-ghla?
Which Somatrogon-ghla supplement interactions are the most serious?
Can I take vitamins or supplements while on Somatrogon-ghla?
Do brands like Ngenla have the same supplement interactions as Somatrogon-ghla?
Where do these interaction ratings come from?
What about Somatrogon-ghla and my other medications?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
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Where This Data Comes From — and Why You Can Trust It
🧪 Licensed clinical database
Every interaction verdict on this page comes from Natural Medicines Pro (TRC Healthcare / Therapeutic Research) — the same evidence-graded reference used by pharmacists and hospitals. We license this data directly; we do not scrape it, and no AI invents an interaction.
🧑⚕️ Pharmacist review
This page is curated and coded by Dr. Brian Staiger, PharmD, BCPS, Clinical Pharmacist, with additional analysis by the HelloPharmacist Pharmacist Team. Editorial commentary is ours; the licensed interaction records are shown as sourced.
🔄 Kept current
Our interaction database refreshes on a weekly cycle, and this page re-checks the live database every time it’s rebuilt — what you see reflects the database as of September 15, 2026.
🔍 Full transparency
How every dataset on this site is sourced, licensed, and updated is documented publicly: our data sources · editorial policy · how we use AI.
Educational information, not medical advice. An interaction being on file does not mean it will happen to you — and absence of one is not proof of safety. Never start or stop a medication or supplement without talking to your pharmacist or doctor.