Medication interaction hub

What Supplements Interact with Deferasirox?

Deferasirox brand names: Exjade, Jadenu. Every interaction below applies to the brands too.

90 Interactions 4 Major 73 Moderate 13 Minor
Curated & coded by · Clinical Pharmacist · Updated September 22, 2026

Drug–supplement interaction data sourced from Natural Medicines Pro, the licensed clinical database from TRC Healthcare / Therapeutic Research, with additional analysis by the HelloPharmacist Pharmacist Team. Our sources · Editorial policy

What is this page for?

One answer, for one medication: what supplements and herbal products interact with Deferasirox? Every vitamin, herb, and supplement ingredient we’ve checked against it is on this page, ranked by severity, each linking to the full report for that exact pair.

This page covers supplement interactions only — to check Deferasirox against your other medications, use the drug–drug interaction checker. Educational information from our licensed clinical databases, not medical advice. Our editorial policy

HelloPharmacist Bottom Line

90 supplements and herbal ingredients have interactions with Deferasirox on file in the HelloPharmacist interaction database — 4 rated major, 73 moderate, and 13 minor. The most serious involve Siberian Cocklebur, Activated Charcoal, Beer and Wine.

Our assessment: with 4 major-rated interactions on the list, this one deserves real attention — know the major entries before combining anything with Deferasirox.

Major 4 Moderate 73 Minor 13 No known interaction 1,362

Ranked by severity below. Every entry links to the full pharmacist-reviewed report for that exact combination — what can happen, how likely it is, and what to do about it.

This box checks one ingredient at a time (like turmeric or magnesium). Taking a supplement product with a whole label of ingredients? Search the product instead — we check every ingredient on it ↓

Most Viewed Ingredient Interactions

Deferasirox: Top Interactions at a Glance

The Deferasirox supplement & herbal interactions people checked most in the last 24 hours, colored by severity. Tap any ingredient to open the full report for that pair.

Showing the 12 highest-ranked of 90 interacting ingredients — plus 1,362 more checked with no known interaction. See the complete ranked list.

Start here

The Most-Checked Deferasirox Combinations Today

The Deferasirox + supplement pages people viewed most in the last 24 hours (resets at midnight). Open any card for the full report.

Moderate Likelihood Possible Black Tea + Deferasiroxi

Theoretically, concomitant use might increase the levels and adverse effects of caffeine.

Read the full interaction Moderate Likelihood Possible Vitamin A + Deferasiroxi

Theoretically, taking high doses of vitamin A in combination with other potentially hepatotoxic drugs might increase the risk of liver disease.

Read the full interaction Minor Likelihood Possible Guarana + Deferasiroxi

Theoretically, concomitant use might increase the levels and adverse effects of caffeine.

Read the full interaction Moderate Likelihood Possible Spearmint + Deferasiroxi

Theoretically, high doses of spearmint might increase the risk of liver damage when taken with hepatotoxic drugs.

Read the full interaction Moderate Likelihood Possible Hound's Tongue + Deferasiroxi

Theoretically, CYP3A4 inducers can increase the toxicity of the pyrrolizidine alkaloid (PA) constituents of hound's tongue.

Read the full interaction Moderate Likelihood Possible Dusty Miller + Deferasiroxi

Theoretically, CYP3A4 inducers might increase the risk of adverse effects from the pyrrolizidine alkaloid (PA) constituents in dusty miller.

Read the full interaction
The complete list

Every Supplement Checked Against Deferasirox

All 1,452 ingredients in our database, ranked by severity — 90 with a Deferasirox interaction on file and 1,362 with none found. Filter by severity or search any ingredient; hover the for what each ingredient is.

Looking for an interaction with a specific supplement product? Search products instead ↓

Straight answers

Can You Take It With Deferasirox?

One-line answers, one card per combination — scroll through today’s 20 and tap any card for the full report. A different set rotates in daily until every combination has had its turn.

Can you take Black Tea with Deferasirox?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use might increase the levels and adverse effects of caffeine.

Full Black Tea + Deferasirox answer

Can you take Vitamin A with Deferasirox?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking high doses of vitamin A in combination with other potentially hepatotoxic drugs might increase the risk of liver disea...

Full Vitamin A + Deferasirox answer

Can you take Guarana with Deferasirox?

Minor Usually — this is a minor-rated interaction, generally not clinically significant but worth mentioning to your pharmacist. Theoretically, concomitant use might increase the levels and adverse effects of caffeine.

Full Guarana + Deferasirox answer

Can you take Spearmint with Deferasirox?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, high doses of spearmint might increase the risk of liver damage when taken with hepatotoxic drugs.

Full Spearmint + Deferasirox answer

Can you take Hound's Tongue with Deferasirox?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, CYP3A4 inducers can increase the toxicity of the pyrrolizidine alkaloid (PA) constituents of hound's tongue.

Full Hound's Tongue + Deferasirox answer

Can you take Lemongrass with Deferasirox?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, lemongrass might increase the clearance and decrease the levels of glucuronidated drugs.

Full Lemongrass + Deferasirox answer

Can you take Ligandrol with Deferasirox?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use might have additive hepatotoxic effects.

Full Ligandrol + Deferasirox answer

Can you take Manchurian Thorn with Deferasirox?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Animal research suggests that high doses of Manchurian thorn can induce liver damage.

Full Manchurian Thorn + Deferasirox answer

Can you take Milk Thistle with Deferasirox?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, milk thistle might affect the clearance of drugs that undergo glucuronidation.

Full Milk Thistle + Deferasirox answer

Can you take Niacin with Deferasirox?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use of niacin and hepatotoxic drugs might increase the risk of hepatotoxicity.

Full Niacin + Deferasirox answer

Can you take Noni with Deferasirox?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, taking noni with hepatotoxic drugs might increase the risk of liver damage.

Full Noni + Deferasirox answer

Can you take Oolong Tea with Deferasirox?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use might increase the levels and adverse effects of the caffeine in oolong tea.

Full Oolong Tea + Deferasirox answer

Can you take Ostarine with Deferasirox?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use with hepatotoxic drugs might increase the risk of adverse hepatotoxic effects.

Full Ostarine + Deferasirox answer

Can you take Padang Cassia with Deferasirox?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. There is some concern that ingesting large amounts of Padang cassia might cause hepatotoxicity in some people.

Full Padang Cassia + Deferasirox answer

Can you take Pu-erh Tea with Deferasirox?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use might increase the levels and adverse effects of caffeine.

Full Pu-erh Tea + Deferasirox answer

Can you take Red Yeast Rice with Deferasirox?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use might increase the risk of liver damage.

Full Red Yeast Rice + Deferasirox answer

Can you take Rhubarb with Deferasirox?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use of rhubarb with potentially hepatotoxic drugs might increase the risk of developing liver damage.

Full Rhubarb + Deferasirox answer

Can you take Saigon Cinnamon with Deferasirox?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, Saigon cinnamon might cause additive effects when used with hepatotoxic drugs.

Full Saigon Cinnamon + Deferasirox answer

Can you take Slippery Elm with Deferasirox?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.

Full Slippery Elm + Deferasirox answer

Can you take Sweet Annie with Deferasirox?

Moderate Possibly, but carefully — this moderate-rated combination may need monitoring, a dose adjustment, or separated timing. Theoretically, concomitant use might have additive adverse hepatotoxic effects.

Full Sweet Annie + Deferasirox answer
Read the list like a pharmacist

What Severity, Likelihood & Evidence Mean

Severity — How Serious It Can Be

  • Major. Clinically significant; generally best avoided, or used only under direct professional supervision.
  • Moderate. May need monitoring, a dose adjustment, or separating the times you take each one.
  • Minor. Generally not clinically significant, but still worth noting and mentioning to your pharmacist.
  • No known interaction. Checked against our sources with nothing documented — not the same as proven safety.

Likelihood — How Well It’s Documented

  • Likely. Well-controlled human studies have demonstrated the likely existence of this interaction
  • Probable. Interaction has not been documented in well-controlled studies, however, the interaction has been demonstrated in some small human studies or in controlled animal studies in conjunction with multiple case reports.
  • Possible. Interaction has been documented in animal or in lab research, or the interaction has been documented in humans but is limited to case reports or conflicting clinical research exists
  • Unlikely. Interaction has been demonstrated in animal or in lab research but has been shown not to occur in humans.

Where This Data Comes From

  • Interaction records are evidence-graded and sourced from the Natural Medicines database (TRC Healthcare), the same reference used by pharmacists and hospitals.
  • Each entry links to a full report with the clinical detail, likelihood, evidence level, and citations for that exact combination.
  • Content is reviewed by licensed HelloPharmacist pharmacists — see our data sources and editorial standards.

How Does Our Interaction Checker Work?

Behind every verdict on this page is a category system. Our source database doesn’t document supplement interactions drug-by-drug — it documents them against groups of medications that behave the same way (for example, “drugs processed by the CYP3A4 liver enzyme” or “blood-thinning medications”).

So the check works in three steps: (1) Deferasirox is classified into the pharmacology categories it belongs to, (2) every supplement interaction documented against any of those categories is inherited by Deferasirox, and (3) each ingredient keeps its own severity, likelihood, and evidence grades from the underlying record. That’s why one supplement can carry several records for one drug — it may interact through more than one category.

Deferasirox sits in 5 interaction categories. Open any one to see what the group means:

Hepatotoxic Drugs 38 ingredients

Medications with known liver considerations. Supplements that can stress the liver add to the load.

38 of the supplement ingredients on this page reach Deferasirox through this category.

Cytochrome P450 3A4 (Cyp3A4) Inducers 19 ingredients

A drug-metabolism group: these medications are processed by the named liver enzyme (a cytochrome P450). Supplements that speed this enzyme up or slow it down can lower or raise the medication's levels in your body.

19 of the supplement ingredients on this page reach Deferasirox through this category.

Oral Drugs 17 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

17 of the supplement ingredients on this page reach Deferasirox through this category.

Glucuronidated Drugs 12 ingredients

A pharmacology grouping from our source database: medications in this group share a property that certain supplements are known to interact with, so an interaction documented for the group applies to every drug in it.

12 of the supplement ingredients on this page reach Deferasirox through this category.

Cytochrome P450 1A2 (Cyp1A2) Inhibitors 10 ingredients

A drug-metabolism group: these medications are processed by the named liver enzyme (a cytochrome P450). Supplements that speed this enzyme up or slow it down can lower or raise the medication's levels in your body.

10 of the supplement ingredients on this page reach Deferasirox through this category.

About Deferasirox

Deferasirox is an iron-chelating medication used to treat chronic iron overload caused by repeated blood transfusions or by non-transfusion-dependent thalassemia syndromes.

Generic name: Deferasirox  ·  Brand names: Exjade, Jadenu.

See the full Deferasirox drug information
Check a real product

Take a Supplement Product? Check the Whole Bottle Against Deferasirox

Most supplements are combination products — and the interaction may come from an ingredient you didn’t buy it for. Search any product below (or scan its label) and we’ll check every ingredient on it against Deferasirox.

Search a supplement product

Type a product name, brand, or UPC — smart search across our full catalog.

Grounded search over our product catalog — every verdict comes from our interaction database, never AI guesswork. How we use AI

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Photograph any Supplement Facts panel — we read the ingredients and check each one against your medications. Free, in seconds.

Open the label scanner

Prefer typing? The interaction checker looks up products by name too.

Products that contain Deferasirox-interacting ingredients

Real supplements from the NIH label database that contain the top interacting ingredients on this page — each one is worth a full label check before combining with Deferasirox.

Zi Sheng Teapills by Plum Flower contains Siberian Cocklebur Cold Away by Health Concerns contains Siberian Cocklebur Sugar Coated Bi Yan Pian by Plum Flower contains Siberian Cocklebur Pe Min Kan Wan by Plum Flower contains Siberian Cocklebur
Pharmacist Counseling Corner

Deferasirox & Supplements: Common Questions

What supplements interact with Deferasirox?
Our database currently documents 90 ingredients with a known Deferasirox interaction (4 major, 73 moderate, 13 minor). The practical move: scan the major group first, then look up the exact supplements you take rather than reading all 90. The highest-ranked right now: Siberian Cocklebur, Activated Charcoal, Beer.
Which Deferasirox supplement interactions are the most serious?
The 4 major-rated combinations — led by Siberian Cocklebur, Activated Charcoal, Beer and Wine — deserve real caution: these are the ones generally best avoided, or used only with your prescriber watching. If you take any of them today, don't panic and don't stop anything abruptly — call your pharmacist first. Jump to the ranked list.
Can I take vitamins or supplements while on Deferasirox?
Plenty of supplements coexist fine with Deferasirox; a shorter list does not. Rather than memorizing it, check the specific ingredients on your labels — the ranked list above covers every one we've checked, and multi-ingredient products can be checked label-by-label with our scanner. Try the label scanner or the interaction checker.
Do brands like Exjade have the same supplement interactions as Deferasirox?
Yes — Exjade, Jadenu all contain Deferasirox, so everything on this page applies to them equally. Interactions belong to the active drug, never to the brand on the box; the same is true of generics.
Where do these interaction ratings come from?
Every rating comes from the Natural Medicines database — the same evidence-graded reference pharmacists and hospitals use — and each interaction carries three separate grades: severity (how bad it can be), likelihood (how well it's documented in studies and case reports), and an evidence level. Our pharmacists review the content; we never let an AI decide an interaction. See how to read the ratings and our editorial policy.
What about Deferasirox and my other medications?
This page covers Deferasirox against supplements and herbal ingredients. Checking Deferasirox against your other prescription or OTC medications is a different tool — our drug interaction checker covers that side. Head to the drug–drug interaction checker, or read the full Deferasirox drug information.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Where next

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Sourcing

Where This Data Comes From — and Why You Can Trust It

🧪 Licensed clinical database

Every interaction verdict on this page comes from Natural Medicines Pro (TRC Healthcare / Therapeutic Research) — the same evidence-graded reference used by pharmacists and hospitals. We license this data directly; we do not scrape it, and no AI invents an interaction.

🧑‍⚕️ Pharmacist review

This page is curated and coded by , Clinical Pharmacist, with additional analysis by the HelloPharmacist Pharmacist Team. Editorial commentary is ours; the licensed interaction records are shown as sourced.

🔄 Kept current

Our interaction database refreshes on a weekly cycle, and this page re-checks the live database every time it’s rebuilt — what you see reflects the database as of September 22, 2026.

🔍 Full transparency

How every dataset on this site is sourced, licensed, and updated is documented publicly: our data sources · editorial policy · how we use AI.

Educational information, not medical advice. An interaction being on file does not mean it will happen to you — and absence of one is not proof of safety. Never start or stop a medication or supplement without talking to your pharmacist or doctor.