Major interaction on record — check this product against your medications before combining. Based on 4 of 8 ingredients. Check your meds →
Dietary supplement

Aces Eyedrops Ingredients & Drug Interactions

by Healing Oasis

Aces Eyedrops label
See full label image
Liquid Category: Other Combinations
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Aces Eyedrops against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Aces Eyedrops is a dietary supplement by Healing Oasis with 8 active ingredients. Its ingredients are commonly taken for common cold and immune support, antioxidant support, skin health and collagen formation.Based on those ingredients, 762 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Vitamin A, Dimethylsulfoxide, Vitamin C. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Aces Eyedrops by Healing Oasis

Ask about any prescription or over-the-counter medication and we check it for interactions with Aces Eyedrops by Healing Oasis — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Aces Eyedrops by Healing Oasis

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 8 active ingredients.

Aces Eyedrops contains 8 ingredients. The active ones are vitamin C, vitamin A, Vitamin E Complex, and four others we'll describe separately.

Vitamin C is an antioxidant; vitamin A supports eye tissue and vision; Vitamin E Complex (tocotrienols) is another antioxidant. Quinton, Methylsulfonylmethane, N-Acetyl L-Carnosine, Dimethylsulfoxide, and Silver round out the formula.

There are no other inactive ingredients listed.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Restore ocular wellness.
  • We looked for evidence on: Age-related macular degeneration (AMD), Cataracts, Corneal abrasion, Dry eye, Presbyopia.
  • The strongest evidence on file: Vitamin C is rated "Possibly Effective" for Cataracts (Natural Medicines).
  • Also on file: Vitamin A is rated "Insufficient Reliable Evidence To Rate" for Cataracts, Corneal abrasion.
  • Also on file: Vitamin C is rated "Insufficient Reliable Evidence To Rate" for Age-related macular degeneration (AMD).

The evidence we hold shows vitamin C is effective for vitamin C deficiency and possibly effective for several eye-related and general health conditions including cataracts and exercise-induced respiratory infections. Vitamin A is effective for vitamin A deficiency and possibly effective for aging skin and measles.

Vitamin E Complex (tocotrienols) is possibly effective for diabetes but possibly ineffective for high cholesterol; evidence for other uses is insufficient. We have no effectiveness data in our records for Quinton, Methylsulfonylmethane, N-Acetyl L-Carnosine, Dimethylsulfoxide, or Silver.

The evidence, ingredient by ingredient Vitamin C Vitamin A Dimethylsulfoxide (dmso) Tocotrienols

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 4 of the 4 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 4 of 4.
  • General safety write-ups exist for 4 of 4.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Vitamin C is generally well tolerated when taken by mouth, applied to skin, or given intravenously, but very high doses can cause stomach cramps, heartburn, nausea, and diarrhea — and in people prone to kidney stones, there's a risk. Vitamin A is generally safe at recommended amounts; very high doses can cause liver damage, headache, and serious effects are rare.

Vitamin E Complex appears well tolerated in studies with no adverse effects reported in clinical trials, though topical use has caused mild itching in a small number of trial participants. For pregnancy and lactation: vitamin C normal amounts are likely safe, but high-dose supplements are possibly unsafe — talk with your doctor.

Vitamin A recommended amounts are likely safe, but high doses (especially retinol) are possibly unsafe due to birth defect risk. Vitamin E Complex has not enough safety data for pregnancy; avoid supplemental doses unless your doctor advises otherwise.

For breastfeeding, vitamin E Complex safety is unclear; avoid supplements unless your healthcare provider recommends it.

Side effects, ingredient by ingredient Vitamin C Vitamin A Dimethylsulfoxide (dmso) Tocotrienols

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 4 of the 4 matched ingredients can interact with medications — Dimethylsulfoxide (dmso), Vitamin A, Vitamin C, Tocotrienols.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; cancer treatments.
  • For scale: 763 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check before using if you take retinoids (tretinoin, isotretinoin, adapalene — Major interaction with vitamin A), estrogens or oral contraceptives, blood thinners (warfarin) or antiplatelet drugs (aspirin), tetracycline antibiotics, or chemotherapy drugs. These are the drug types with documented interactions in the product's ingredients.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence for its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

If you use prescription acne treatments, retinoid creams, birth control pills, hormone therapy, blood thinners, or chemotherapy, check with your pharmacist before using this eyedrop. Even though it's topical, some of these ingredients can be absorbed systemically.

Most people will tolerate the vitamins well at these doses, but the ingredient list includes several we couldn't verify for safety data.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 4 of 8 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 22, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Aces Eyedrops, straight from the product label.

Brand Healing Oasis
Net contents 5 mL
Market status On market
Date entered into DSLD Jun 22, 2023
DSLD ID 297035
Product type Other Combinations
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Aces Eyedrops by Healing Oasis, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Drop(s)
Maximum serving Sizes:
1 Drop(s)
Servings per container
100
IngredientAmount% DV
Vitamin C0 NP--
Vitamin A0 NP--
Quinton0 NP--
Methylsulfonylmethane0 NP--
N-Acetyl L-Carnosine0 NP--
Dimethylsulfoxide0 NP--
Vitamin E Complex0 NP--
Silver0 NP--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Sacramental healing use: 1 drop in each eye twice a day or as guided. Take at least 5 minutes away from other eyedrops.

Precautions

Take at least 5 minutes away from other eyedrops.

Discontinue if drops become

Storage

Keep refrigerated.

Brand IP Statement(s)

Copyright September 2020 Healing Oasis

Formulation

Restore Ocular Wellness...

Vegetarian/Vegan

FDA Statement of Identity

A Healing Sacrament

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Aces Eyedrops by Healing Oasis label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Aces Eyedrops label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Aces Eyedrops by Healing Oasis

These are the 8 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Drop(s) Dosage formLiquid Servings per container100 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Vitamin C

Interacts with
207 drugs
0 NP per serving Form: L-Ascorbic Acid

Vitamin C (ascorbic acid) is an essential nutrient your body needs but cannot make, so you must get it from food or supplements. It's important for im...

Vitamin C monograph & interactions

Vitamin A

Interacts with
387 drugs
0 NP per serving Form: Retinyl Palmitate

Vitamin A is an essential nutrient important for vision, skin, immune function, and growth. Most people get enough from a balanced diet, and supplemen...

Vitamin A monograph & interactions

Quinton

0 NP per serving Form: Micro-Filtered SeaWater

Methylsulfonylmethane

0 NP per serving

N-Acetyl L-Carnosine

0 NP per serving

Dimethylsulfoxide

Interacts with
339 drugs
0 NP per serving

DMSO is a colorless liquid solvent that people apply to the skin for pain and inflammation, and it is FDA-approved (as a prescription) only for inters...

Dimethylsulfoxide monograph & interactions

Vitamin E Complex

Interacts with
122 drugs
0 NP per serving

Tocotrienols are a less common form of vitamin E with strong antioxidant activity studied mostly for cholesterol, liver, and heart health. Early resea...

Vitamin E Complex monograph & interactions

Silver

0 NP per serving Form: Colloidal Silver
Interaction report

Aces Eyedrops by Healing Oasis Drug Interactions

Want to check YOUR meds against Aces Eyedrops?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
762Drugs
9 Major 749 Moderate 4 Minor

Ingredients driving the most interactions

Vitamin A 387
Dimethylsulfoxide 339
Vitamin C 207
Vitamin E Complex 122

Individual Drug Interactions

The ingredients in Aces Eyedrops interact with 762 drugs. Click any drug to see the details.

4 of the 8 ingredients in Aces Eyedrops interact with drugs. Each result below shows which ingredient is responsible. Vitamin A Dimethylsulfoxide Vitamin C Vitamin E Complex

Each ingredient & the kinds of drugs it affects

For each ingredient in Aces Eyedrops with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Vitamin A4 drug types · 387 drugs

Retinoids

Concomitant use of retinoids with vitamin A supplements might produce supratherapeutic vitamin A levels.
Retinoids, which are vitamin A derivatives, could have additive toxic effects when taken with vitamin A supplements.

Likelihood Probable Evidence D
Hepatotoxic Drugs

Theoretically, taking high doses of vitamin A in combination with other potentially hepatotoxic drugs might increase the risk of liver disease.
The tolerable upper intake level (UL) is the highest level of intake that is likely to pose no risk of adverse effects. Doses of vitamin A above the UL can cause hepatotoxicity, ranging from elevated liver enzymes to liver failure.

Likelihood Possible Evidence C
Tetracycline Antibiotics

Theoretically, taking tetracycline antibiotics with high doses of vitamin A can increase the risk of pseudotumor cerebri.
Benign intracranial hypertension (pseudotumor cerebri) can occur with tetracyclines and with acute or chronic vitamin A toxicity. Case reports suggest that taking tetracyclines and vitamin A concurrently can increase the risk of this condition. Avoid high doses of vitamin A in people taking tetracyclines chronically.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, high doses of vitamin A could increase the risk of bleeding with warfarin.
Vitamin A toxicity is associated with hemorrhage and hypoprothrombinemia, possibly due to vitamin K antagonism. Advise patients taking warfarin to avoid doses of vitamin A above the tolerable upper intake level of 10,000 IU/day for adults.

Likelihood Possible Evidence D
Vitamin A full monograph & interactions

Dimethylsulfoxide8 drug types · 339 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, DMSO might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
In vitro evidence shows that DMSO inhibits adenosine diphosphate- and thrombin-induced platelet aggregation.

Likelihood Possible Evidence D
Carboplatin (Paraplatin)

In vitro research shows that DMSO reduces carboplatin cytotoxicity by inducing ligand displacement. Theoretically, using DMSO as a solvent for carboplatin may reduce its chemotherapeutic effects.

Likelihood Possible Evidence D
Cholinergic Drugs

Theoretically, DMSO might increase the risk of cholinergic adverse effects when taken with cholinergic drugs.
In vitro and animal research suggests that DMSO inhibits acetylcholinesterase activity.

Likelihood Possible Evidence D
Cisplatin (Platinol-Aq)

In vitro research shows that DMSO reduces cisplatin cytotoxicity by inducing ligand displacement. Theoretically, using DMSO as a solvent for cisplatin may reduce its chemotherapeutic effects.

Likelihood Possible Evidence D
Platinum Agents

Theoretically, using DMSO as a solvent for platinum-based chemotherapeutic agents may reduce chemotherapeutic effects.
In vitro research shows that DMSO reduces the cytotoxicity of cisplatin, carboplatin, and oxaliplatin by inducing ligand displacement.

Likelihood Possible Evidence D
Sulindac (Clinoril)

DMSO might reduce the effectiveness of sulindac and increase the risk of peripheral neuropathy.
Taking DMSO orally with sulindac has been reported to reduce the metabolism of sulindac into its active metabolite. This might reduce the effectiveness of sulindac. Furthermore, using topical DMSO concomitantly with sulindac has been linked with peripheral neuropathy.

Likelihood Probable Evidence B
Topical Drugs

Topical DMSO might increase the effects and adverse effects of topical drugs.
Evidence from animal studies and limited human studies suggests that DMSO may potentiate the action of numerous topical medications by increasing their absorption through the skin. This increase in absorption seems to depend on the concentration of DMSO and the molecular weight of the medication.

Likelihood Possible Evidence B
Verteporfin (Visudyne)

Theoretically, DMSO might reduce the effects of verteporfin.
In vitro, DMSO has been shown to scavenge free radicals and improve mitochondrial oxidative phosphorylation. This can theoretically decrease the effects of verteporfin.

Likelihood Possible Evidence D
Dimethylsulfoxide full monograph & interactions

Vitamin C13 drug types · 207 drugs

Alkylating Agents

Theoretically, antioxidant effects of vitamin C might reduce the effectiveness of alkylating agents.
The use of antioxidants like vitamin C during chemotherapy is controversial. There is concern that antioxidants could reduce the activity of chemotherapy drugs that generate free radicals, such as cyclophosphamide, chlorambucil, carmustine, busulfan, and thiotepa. In contrast, some researchers theorize that antioxidants might make chemotherapy more effective by reducing oxidative stress that could interfere with apoptosis (cell death) of cancer cells. More evidence is needed to determine what effect, if any, antioxidants such as vitamin C have on chemotherapy.

Likelihood Possible Evidence D
Aluminum

Vitamin C can increase the amount of aluminum absorbed from aluminum compounds.
Research in animals and humans shows that vitamin C increases aluminum absorption, theoretically by chelating aluminum and keeping it in solution where it is available for absorption. In people with normal renal function, urinary excretion of aluminum will likely increase, making aluminum retention and toxicity unlikely. Patients with renal failure who take aluminum-containing compounds such as phosphate binders should avoid vitamin C supplements in doses above the recommended dietary allowances.

Likelihood Probable Evidence B
Antitumor Antibiotics

Theoretically, the antioxidant effects of vitamin C might reduce the effectiveness of antitumor antibiotics.
The use of antioxidants like vitamin C during chemotherapy is controversial. There is concern that antioxidants could reduce the activity of chemotherapy drugs which generate free radicals, such as doxorubicin. In contrast, some researchers theorize that antioxidants might make chemotherapy more effective by reducing oxidative stress that could interfere with apoptosis (cell death) of cancer cells. More evidence is needed to determine what effects, if any, antioxidants such as vitamin C have on chemotherapy.

Likelihood Possible Evidence D
Estrogens

Vitamin C might increase blood levels of estrogens.
Increases in plasma estrogen levels of up to 55% occur under some circumstances when vitamin C is taken concurrently with oral contraceptives or hormone replacement therapy, including topical products. It is suggested that vitamin C prevents oxidation of estrogen in the tissues, regenerates oxidized estrogen, and reduces sulfate conjugation of estrogen in the gut wall. When tissue levels of vitamin C are high, these processes are already maximized and supplemental vitamin C does not have any effect on estrogen levels. Increases in plasma estrogen levels may occur when patients who are deficient in vitamin C take supplements. Monitor these patients for estrogen-related side effects.

Likelihood Probable Evidence B
Fluphenazine (Prolixin)

Theoretically, vitamin C might decrease levels of fluphenazine.
In one patient there was a clinically significant decrease in fluphenazine levels when vitamin C (500 mg twice daily) was started. The mechanism is not known, and there is no further data to confirm this interaction.

Likelihood Possible Evidence D
Indinavir (Crixivan)

Vitamin C can modestly reduce indinavir levels.
One pharmacokinetic study shows that taking vitamin C 1 gram orally once daily along with indinavir 800 mg orally three times daily reduces the area under the concentration-time curve of indinavir by 14%. The mechanism of this interaction is unknown, but it is unlikely to be clinically significant in most patients. The effect of higher doses of vitamin C on indinavir levels is unknown.

Likelihood Probable Evidence B
Levothyroxine (Synthroid, Others)

Vitamin C can increase levothyroxine absorption.
Two clinical studies in adults with poorly controlled hypothyroidism show that swallowing levothyroxine with a glass of water containing vitamin C 500-1000 mg in solution reduces thyroid stimulating hormone (TSH) levels and increases thyroxine (T4) levels when compared with taking levothyroxine alone. This suggests that vitamin C increases the oral absorption of levothyroxine, possibly due to a reduction in pH.

Likelihood Probable Evidence B
Warfarin (Coumadin)

High-dose vitamin C might reduce the levels and effectiveness of warfarin.
Vitamin C in high doses may cause diarrhea and possibly reduce warfarin absorption. There are reports of two people who took up to 16 grams daily of vitamin C and had a reduction in prothrombin time. Lower doses of 5-10 grams daily can also reduce warfarin absorption. In many cases, this does not seem to be clinically significant. However, a case of warfarin resistance has been reported for a patient who took vitamin C 500 mg twice daily. Cessation of vitamin C supplementation resulted in a rapid increase in international normalized ratio (INR). Tell patients taking warfarin to avoid taking vitamin C in excessively high doses (greater than 10 grams daily). Lower doses may be safe, but the anticoagulation activity of warfarin should be monitored. Patients who are stabilized on warfarin while taking vitamin C should avoid adjusting vitamin C dosage to prevent the possibility of warfarin resistance.

Likelihood Possible Evidence D
Acetaminophen (Tylenol, Others)

High-dose vitamin C might slightly prolong the clearance of acetaminophen.
A small pharmacokinetic study in healthy volunteers shows that taking high-dose vitamin C (3 grams) 1.5 hours after taking acetaminophen 1 gram slightly increases the apparent half-life of acetaminophen from around 2.3 hours to 3.1 hours. Ascorbic acid competitively inhibits sulfate conjugation of acetaminophen. However, to compensate, elimination of acetaminophen glucuronide and unconjugated acetaminophen increases. This effect is not likely to be clinically significant.

Likelihood Probable Evidence B
Aspirin

Acidification of the urine by vitamin C might increase aspirin levels.
It has been suggested that acidification of the urine by vitamin C could increase reabsorption of salicylates by the renal tubules, and increase plasma salicylate levels. However, short-term use of up to 6 grams daily of vitamin C does not seem to affect urinary pH or salicylate excretion, suggesting this interaction is not clinically significant.

Likelihood Possible Evidence B
Choline Magnesium Trisalicylate (Trilisate)

Acidification of the urine by vitamin C might increase choline magnesium trisalicylate levels.
It has been suggested that acidification of the urine by vitamin C could increase reabsorption of salicylates by the renal tubules, and increase plasma salicylate levels. However, short-term use of up to 6 grams daily of vitamin C does not seem to affect urinary pH or salicylate excretion, suggesting this interaction probably is not clinically significant.

Likelihood Possible Evidence B
Niacin

Vitamin C might decrease the beneficial effects of niacin on high-density lipoprotein (HDL) cholesterol levels.
A combination of niacin and simvastatin (Zocor) effectively raises HDL cholesterol levels in patients with coronary disease and low HDL levels. Clinical research shows that taking a combination of antioxidants (vitamin C, vitamin E, beta-carotene, and selenium) along with niacin and simvastatin (Zocor) attenuates this rise in HDL, specifically the HDL-2 and apolipoprotein A1 fractions, by more than 50% in patients with coronary disease. It is not known whether this adverse effect is due to a single antioxidant such as vitamin C, or to the combination. It also is not known whether it will occur in other patient populations.

Likelihood Possible Evidence A
Salsalate (Disalcid)

Acidification of the urine by vitamin C might increase salsalate levels.
It has been suggested that acidification of the urine by vitamin C could increase reabsorption of salicylates by the renal tubules, and increase plasma salicylate levels. However, short-term use of up to 6 grams/day vitamin C does not seem to affect urinary pH or salicylate excretion, suggesting this interaction probably is not clinically significant.

Likelihood Possible Evidence B
Vitamin C full monograph & interactions

Vitamin E Complex1 drug type · 122 drugs

Anticoagulant/Antiplatelet Drugs

Concomitant use of tocotrienols with anticoagulant or antiplatelet agents might increase the risk of bleeding. However, this has not been reported in humans.
Taking tocotrienols orally inhibits experimentally-induced platelet aggregation in humans. Theoretically tocotrienols might increase the risk of bleeding if taken with antiplatelet or anticoagulant drugs. However, tocotrienols 400-800 mg daily have been used with aspirin and/or clopidogrel for 1 year with no clear cumulative antiplatelet effects and no reports of bleeding.

Likelihood Unlikely Evidence B
Vitamin E Complex full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Aces Eyedrops, from the product label.

Healing Oasis

See all Healing Oasis products
Name
Healing Oasis
Street Address
351 Wailuku Drive
City
Hilo
State
Hawaii-Kingdom
Phone Number
888-417-8118
Pharmacist Counseling Corner

Aces Eyedrops by Healing Oasis: Common Questions

Does Aces Eyedrops by Healing Oasis interact with any medications?
Yes. Based on its ingredients, Aces Eyedrops has a known interaction with 762 medications, including 9 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Aces Eyedrops contains 8 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this eyedrop interact with my birth control pill?
Vitamin C in this product might increase blood levels of estrogen from birth control pills or hormone therapy — a Moderate interaction. The effect can range up to 55% in some cases. Talk to your pharmacist or doctor before starting, especially if you're concerned about breakthrough bleeding or other hormonal effects.
Can I use this if I'm on warfarin (Coumadin)?
Both vitamin C and vitamin A in this product interact with warfarin at Moderate severity. Vitamin C in high doses may reduce warfarin's effectiveness, and vitamin A toxicity is linked to increased bleeding risk. You'll need to discuss this with your doctor or pharmacist to see if it's safe for you.
Is this safe during pregnancy?
Vitamin C normal amounts are likely safe in pregnancy, but high-dose supplements are possibly unsafe. Vitamin A recommended amounts are likely safe, but high doses — especially as retinol — are possibly unsafe and carry birth defect risk. Talk with your doctor before using, since we can't give personalized advice on what's right for your situation.
What's vitamin E Complex (tocotrienols) in here for?
Vitamin E Complex is an antioxidant. Our data shows it's possibly effective for diabetes but possibly ineffective for high cholesterol. Long-term safety at supplement doses isn't well established, so we recommend discussing its role in this product with your pharmacist.
What are the side effects of vitamin C in an eyedrop?
Topically applied vitamin C causes irritation and tingling in some people. When taken by mouth, it can cause stomach cramps, heartburn, and diarrhea — mainly at doses above 2 grams daily — but at eyedrop amounts, systemic effects are less likely.
Is this safe if I use tretinoin (Retin-A) for acne?
No — this is a Major interaction. Vitamin A in this product combined with tretinoin or other retinoids can cause dangerously high vitamin A levels. Do not use this product if you're on a retinoid prescription. Talk to your doctor or dermatologist about safe alternatives.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Aces Eyedrops label
Go deeper

The Full Monographs Behind Aces Eyedrops’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Vitamin C

Interacts with 207 drugs

Vitamin C (ascorbic acid) is an essential nutrient your body needs but cannot make, so you must get it from food or supplements. It's important for immune function, collagen, and acts as an...

Read the full Vitamin C monograph → Herb & supplement monograph

Vitamin A

Interacts with 387 drugs

Vitamin A is an essential nutrient important for vision, skin, immune function, and growth. Most people get enough from a balanced diet, and supplements are mainly useful for correcting a tr...

Read the full Vitamin A monograph → Herb & supplement monograph

Dimethylsulfoxide (dmso)

Interacts with 339 drugs

DMSO is a colorless liquid solvent that people apply to the skin for pain and inflammation, and it is FDA-approved (as a prescription) only for interstitial cystitis placed directly into the...

Read the full Dimethylsulfoxide (dmso) monograph → Herb & supplement monograph

Tocotrienols

Interacts with 122 drugs

Tocotrienols are a less common form of vitamin E with strong antioxidant activity studied mostly for cholesterol, liver, and heart health. Early research is interesting but far from conclusi...

Read the full Tocotrienols monograph →
Sources

Sources & How We Checked

Aces Eyedrops's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 113 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Vitamin C 51 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Back DJ, Breckenridge AM, MacIver M, et al. Interaction of ethinyloestradiol with ascorbic acid in man. Br Med J (Clin Res Ed) 1981;282:1516.
  3. Morris JC, Beeley L, Ballantine N. Interaction of ethinyloestradiol with ascorbic acid in man [letter]. Br Med J (Clin Res Ed) 1981;283:503.
  4. Labriola D, Livingston R. Possible interactions between dietary antioxidants and chemotherapy. Oncology 1999;13:1003-8.
  5. Dwyer JH, Merz NB, Shirocre AM, et al. Progression of early atherosclerosis and intake of vitamin C and vitamin E from supplements and food. The Los Angeles Atherosclerosis Study. 41st Annual Conference on Cardiovascular Disease Epidemiology and Prevent
  6. Levine M, Rumsey SC, Daruwala R, et al. Criteria and recommendations for vitamin C intake. JAMA 1999;281:1415-23. PubMed
  7. Hansten PD, Horn JR. Drug Interactions Analysis and Management. Vancouver, WA: Applied Therapeutics Inc., 1997 and updates.
  8. Segal S, Kaminski S. Drug-nutrient interactions. American Druggist 1996 Jul;42-8.
  9. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin C, Vitamin E, Selenium, and Carotenoids. Washington, DC: National Academy Press, 2000. Available at: http://www.nap.edu/books/0309069351/html/.
  10. Houston JB, Levy G. Drug biotransformation interactions in man VI: Acetaminophen and ascorbic acid. J Pharm Sci 1976;65:1218-21. PubMed
  11. Brown BG, Zhao XQ, Chait A, et al. Simvastatin and niacin, antioxidant vitamins, or the combination for the prevention of coronary disease. N Engl J Med 2001;345:1583-93. DOI
  12. Rosenthal G. Interaction of ascorbic acid and warfarin. JAMA 1971;215:1671. DOI
  13. Hume R, Johnstone JM, Weyers E. Interaction of ascorbic acid and warfarin. JAMA 1972;219:1479. DOI
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Vitamin A 31 references
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Dimethylsulfoxide (dmso) 27 references
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See these in context on the Dimethylsulfoxide (dmso) monograph →

Tocotrienols 4 references
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  2. Baumann LS, Spencer JS. The effects of topical vitamin E on the cosmetic appearance of scars. Dermatol Surg 1999;25:311-5. PubMed
  3. Khoo TL, Halim AS, Zakaria Z, Mat Saad AZ, Wu LY, Lau HY. A prospective, randomised, double-blinded trial to study the efficacy of topical tocotrienol in the prevention of hypertrophic scars. J Plast Reconstr Aesthet Surg. 2011 Jun;64(6):e137-45. Epub 201 PubMed
  4. Slivka A, Rink C, Paoletto D, Sen CK. Platelet function in stroke/transient ischemic attack patients treated with tocotrienol. FASEB J. 2020;34(9):11838-11843. PubMed

See these in context on the Tocotrienols monograph →

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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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