Activated Charcoal 520 mg Ingredients & Drug Interactions
by GNC
What is this page for?
First and foremost: checking Activated Charcoal 520 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Activated Charcoal 520 mg is a dietary supplement by GNC with 1 active ingredient. Its ingredients are commonly taken for poisoning and drug overdose (in emergency care), gas and bloating, upset stomach.Based on those ingredients, 2,027 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Activated Charcoal. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Activated Charcoal 520 mg by GNC
Ask about any prescription or over-the-counter medication and we check it for interactions with Activated Charcoal 520 mg by GNC — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Activated Charcoal 520 mg by GNC
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: activated charcoal at 520 mg per capsule. Activated charcoal is a form of carbon that's been processed to make it very porous, which allows it to bind to substances in your digestive tract.
The capsule also contains cellulose and magnesium stearate as inactive ingredients.
Does it work?
Moderate evidence
The evidence we hold shows activated charcoal is possibly effective for poisoning. For other uses listed — hyperphosphatemia, wound healing, indigestion (dyspepsia), hangover, and high cholesterol — the available data is insufficient to rate it either way.
If you're considering this for a specific health concern, talk with your pharmacist about what the science actually supports.
How safe is it?
Well-documented data
Activated charcoal is generally well tolerated for short-term use, but constipation is the most common side effect — it's usually temporary. You may also notice black stools, belly pain, bloating, or gas.
Rarely, it can cause a blockage in your digestive tract. The safety data for pregnancy and breastfeeding is limited, so if you're pregnant or nursing, check with your doctor or pharmacist before using it.
Meds to double-check
Major interaction found
Before taking this product, double-check all your regular medications — activated charcoal can reduce the absorption of many oral drugs and make them less effective (Major severity). Also check if you take oral contraceptive pills, as charcoal may reduce their effectiveness (Moderate).
Avoid taking alcohol at the same time, as it can weaken the charcoal's binding action (Moderate).
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Major medication interactions have been identified, and safety information is well characterized.
Activated charcoal can be useful in specific situations like certain poisonings, but it interferes with many medications by reducing how much of them your body absorbs. If you take any regular medications, especially oral contraceptives, heart drugs, or seizure preventers, you need to check them against this product first.
Talk to your pharmacist before starting.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 23, 2017.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Activated Charcoal 520 mg, straight from the product label.
| Brand | GNC |
|---|---|
| Barcode (UPC) | 048107175528 |
| Net contents | 60 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Jun 23, 2017 |
| DSLD ID | 75292 |
| Product type | Non-nutrient/non-botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Activated Charcoal 520 mg by GNC, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Activated Charcoal | 520 mg | -- |
Other ingredients: Cellulose, Magnesium Stearate
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
Made in India Actual size
Promotes natural relief of gas and absorbs toxins
FDA Statement of Identity
Dietary Supplement
General
CODE 988614 KRG
Suggested/Recommended/Usage/Directions
Directions: As a dietary supplement, take up to 2-3 servings daily after consuming a meal. Do not exceed recommended dose.
Precautions
Do not exceed recommended dose.
Warning: Adult use only.
Consult your physician prior to using this product if you are pregnant, nursing, taking medication, or have a medical condition.
Discontinue use two weeks prior to surgery.
Do not consume at the same time as any medicines or other dietary supplement, as this may interfere with their effectiveness.
This product is not intended as treatment for accidental poisoning.
Keep out of reach of children.
Formulation
No sugar, no starch, no artificial colors, no artificial flavors, no preservatives, sodium free, no wheat, gluten free, no corn, no soy, no dairy, yeast free.
Storage
Store in a cool, dry place.
FDA Disclaimer Statement
This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Activated Charcoal 520 mg by GNC label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Activated Charcoal 520 mg by GNC
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.
Activated Charcoal
Interacts with2,027 drugs
Activated charcoal is a highly porous form of carbon that can bind certain substances in the gut, and it is used in hospitals to treat some poisonings...
Activated Charcoal monograph & interactionsOther (inactive) ingredients: Cellulose, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.
Activated Charcoal 520 mg by GNC Drug Interactions
HelloPharmacist Interaction Report
GNC's Activated Charcoal 520 mg can interact with a significant number of medications.
The most serious concern is with oral drugs — activated charcoal binds to many medications in your gut and reduces how much of them your body absorbs, which can make them less effective. This applies to a broad range of drugs, including heart medications, seizure preventers, and pain relievers.
Altogether, these interactions span 2,028 individual medications.
Read the full breakdown — every affected drug type, severity by severity
Activated charcoal may also reduce how well oral contraceptives work, raising the risk of contraceptive failure — this is a Moderate-severity interaction. Additionally, alcohol can weaken charcoal's binding ability, so drinking while taking this product may reduce its effectiveness.
Because of the breadth of drugs affected, it's essential to check your exact medications using the search tool on this page before you start. If you take any prescription or over-the-counter medication regularly, run it through first.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Activated Charcoal 520 mg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Activated Charcoal 520 mg interact with 2,027 drugs. Click any drug to see the details.
1 of the 1 ingredient in Activated Charcoal 520 mg interact with drugs. Each result below shows which ingredient is responsible. Activated Charcoal
Acetaminophen, DiphenhydramineTylenol PM, Tylenol PM Ex Strength
How Acetaminophen, Diphenhydramine interacts with Activated Charcoal 520 mg — through 1 ingredient. Tap an ingredient for the detail:
Activated CharcoalOral Drugs Major
Interaction Summary
Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.
Read the full Activated Charcoal + Acetaminophen, Diphenhydramine interactionAcetaminophen, Diphenhydramine, PseudoephedrineChildren's Tylenol Allergy, Cold Control, Contac Night Allergy Relief
How Acetaminophen, Diphenhydramine, Pseudoephedrine interacts with Activated Charcoal 520 mg — through 1 ingredient. Tap an ingredient for the detail:
Activated CharcoalOral Drugs Major
Interaction Summary
Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.
Read the full Activated Charcoal + Acetaminophen, Diphenhydramine, Pseudoephedrine interactionAcetaminophen, Doxylamine, PseudoephedrineEx Strength Tylenol Sinus Nighttime
How Acetaminophen, Doxylamine, Pseudoephedrine interacts with Activated Charcoal 520 mg — through 1 ingredient. Tap an ingredient for the detail:
Activated CharcoalOral Drugs Major
Interaction Summary
Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.
Read the full Activated Charcoal + Acetaminophen, Doxylamine, Pseudoephedrine interactionAcetaminophen, HydrocodoneAnexsia, Anodynos DHC, Azdone, Co-Gesic, Doucet, Lorcet +9 more
How Acetaminophen, Hydrocodone interacts with Activated Charcoal 520 mg — through 1 ingredient. Tap an ingredient for the detail:
Activated CharcoalOral Drugs Major
Interaction Summary
Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.
Read the full Activated Charcoal + Acetaminophen, Hydrocodone interactionAcetaminophen, IbuprofenCombogesic
How Acetaminophen, Ibuprofen interacts with Activated Charcoal 520 mg — through 1 ingredient. Tap an ingredient for the detail:
Activated CharcoalOral Drugs Major
Interaction Summary
Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.
Read the full Activated Charcoal + Acetaminophen, Ibuprofen interactionAcetaminophen, MeperidineDemerol APAP
How Acetaminophen, Meperidine interacts with Activated Charcoal 520 mg — through 1 ingredient. Tap an ingredient for the detail:
Activated CharcoalOral Drugs Major
Interaction Summary
Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.
Read the full Activated Charcoal + Acetaminophen, Meperidine interactionAcetaminophen, MethocarbamolRobaxacet
How Acetaminophen, Methocarbamol interacts with Activated Charcoal 520 mg — through 1 ingredient. Tap an ingredient for the detail:
Activated CharcoalOral Drugs Major
Interaction Summary
Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.
Read the full Activated Charcoal + Acetaminophen, Methocarbamol interactionAcetaminophen, OrphenadrineOrfenagesic
How Acetaminophen, Orphenadrine interacts with Activated Charcoal 520 mg — through 1 ingredient. Tap an ingredient for the detail:
Activated CharcoalOral Drugs Major
Interaction Summary
Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.
Read the full Activated Charcoal + Acetaminophen, Orphenadrine interactionAcetaminophen, OxycodonePercocet, Roxicet, Tylox, Xartemis XR
How Acetaminophen, Oxycodone interacts with Activated Charcoal 520 mg — through 1 ingredient. Tap an ingredient for the detail:
Activated CharcoalOral Drugs Major
Interaction Summary
Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.
Read the full Activated Charcoal + Acetaminophen, Oxycodone interactionAcetaminophen, Pamabrom, PyrilamineMidol Max Strength PMS, Pamprin, Pamprin ES
How Acetaminophen, Pamabrom, Pyrilamine interacts with Activated Charcoal 520 mg — through 1 ingredient. Tap an ingredient for the detail:
Activated CharcoalOral Drugs Major
Interaction Summary
Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.
Read the full Activated Charcoal + Acetaminophen, Pamabrom, Pyrilamine interactionAcetaminophen, PentazocineTalacen
How Acetaminophen, Pentazocine interacts with Activated Charcoal 520 mg — through 1 ingredient. Tap an ingredient for the detail:
Activated CharcoalOral Drugs Major
Interaction Summary
Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.
Read the full Activated Charcoal + Acetaminophen, Pentazocine interactionAcetaminophen, Phenylephrine, ChlorpheniramineSuper Cold Tabs
How Acetaminophen, Phenylephrine, Chlorpheniramine interacts with Activated Charcoal 520 mg — through 1 ingredient. Tap an ingredient for the detail:
Activated CharcoalOral Drugs Major
Interaction Summary
Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.
Read the full Activated Charcoal + Acetaminophen, Phenylephrine, Chlorpheniramine interactionAcetaminophen, PhenylpropanolamineTetra Caps
How Acetaminophen, Phenylpropanolamine interacts with Activated Charcoal 520 mg — through 1 ingredient. Tap an ingredient for the detail:
Activated CharcoalOral Drugs Major
Interaction Summary
Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.
Read the full Activated Charcoal + Acetaminophen, Phenylpropanolamine interactionAcetaminophen, Phenylpropanolamine, PhenyltoloxamineSinubid
How Acetaminophen, Phenylpropanolamine, Phenyltoloxamine interacts with Activated Charcoal 520 mg — through 1 ingredient. Tap an ingredient for the detail:
Activated CharcoalOral Drugs Major
Interaction Summary
Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.
Read the full Activated Charcoal + Acetaminophen, Phenylpropanolamine, Phenyltoloxamine interactionAcetaminophen, PhenyltoloxaminePercogesic, Relagesic
How Acetaminophen, Phenyltoloxamine interacts with Activated Charcoal 520 mg — through 1 ingredient. Tap an ingredient for the detail:
Activated CharcoalOral Drugs Major
Interaction Summary
Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.
Read the full Activated Charcoal + Acetaminophen, Phenyltoloxamine interactionAcetaminophen, Phenyltoloxamine, SalicylamideLobac
How Acetaminophen, Phenyltoloxamine, Salicylamide interacts with Activated Charcoal 520 mg — through 1 ingredient. Tap an ingredient for the detail:
Activated CharcoalOral Drugs Major
Interaction Summary
Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.
Read the full Activated Charcoal + Acetaminophen, Phenyltoloxamine, Salicylamide interactionAcetaminophen, PropoxypheneDarvocet-N 100, Darvocet-N 50, E-Lor, Wygesic
How Acetaminophen, Propoxyphene interacts with Activated Charcoal 520 mg — through 1 ingredient. Tap an ingredient for the detail:
Activated CharcoalOral Drugs Major
Interaction Summary
Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.
Read the full Activated Charcoal + Acetaminophen, Propoxyphene interactionAcetaminophen, PseudoephedrineChildren's Tylenol Sinus, Dristan N.D., Non-Aspirin Sinus, Ornex, Ornex-Max, Sinutab +5 more
How Acetaminophen, Pseudoephedrine interacts with Activated Charcoal 520 mg — through 1 ingredient. Tap an ingredient for the detail:
Activated CharcoalOral Drugs Major
Interaction Summary
Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.
Read the full Activated Charcoal + Acetaminophen, Pseudoephedrine interactionAcetaminophen, Pseudoephedrine, TriprolidineActifed Plus ES
How Acetaminophen, Pseudoephedrine, Triprolidine interacts with Activated Charcoal 520 mg — through 1 ingredient. Tap an ingredient for the detail:
Activated CharcoalOral Drugs Major
Interaction Summary
Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.
Read the full Activated Charcoal + Acetaminophen, Pseudoephedrine, Triprolidine interactionAcetazolamideAk-Zol, Diamox
How Acetazolamide interacts with Activated Charcoal 520 mg — through 1 ingredient. Tap an ingredient for the detail:
Activated CharcoalOral Drugs Major
Interaction Summary
Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.
Read the full Activated Charcoal + Acetazolamide interactionAcetohexamideDymelor
How Acetohexamide interacts with Activated Charcoal 520 mg — through 1 ingredient. Tap an ingredient for the detail:
Activated CharcoalOral Drugs Major
Interaction Summary
Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.
Read the full Activated Charcoal + Acetohexamide interactionAcetohydroxamic AcidLithostat
How Acetohydroxamic Acid interacts with Activated Charcoal 520 mg — through 1 ingredient. Tap an ingredient for the detail:
Activated CharcoalOral Drugs Major
Interaction Summary
Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.
Read the full Activated Charcoal + Acetohydroxamic Acid interactionAcetophenazineTindal
How Acetophenazine interacts with Activated Charcoal 520 mg — through 1 ingredient. Tap an ingredient for the detail:
Activated CharcoalOral Drugs Major
Interaction Summary
Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.
Read the full Activated Charcoal + Acetophenazine interactionAcetylcholineMiochol-E
How Acetylcholine interacts with Activated Charcoal 520 mg — through 1 ingredient. Tap an ingredient for the detail:
Activated CharcoalOral Drugs Major
Interaction Summary
Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.
Read the full Activated Charcoal + Acetylcholine interactionAcetylcysteine (prescription Drug)Cetylev, Legubeti
How Acetylcysteine (prescription Drug) interacts with Activated Charcoal 520 mg — through 1 ingredient. Tap an ingredient for the detail:
Activated CharcoalOral Drugs Major
Interaction Summary
Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.
Read the full Activated Charcoal + Acetylcysteine (prescription Drug) interactionAcetylsalicylic AcidEntrophen
How Acetylsalicylic Acid interacts with Activated Charcoal 520 mg — through 1 ingredient. Tap an ingredient for the detail:
Activated CharcoalOral Drugs Major
Interaction Summary
Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.
Read the full Activated Charcoal + Acetylsalicylic Acid interactionAcitretinSoriatane
How Acitretin interacts with Activated Charcoal 520 mg — through 1 ingredient. Tap an ingredient for the detail:
Activated CharcoalOral Drugs Major
Interaction Summary
Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.
Read the full Activated Charcoal + Acitretin interactionAcrivastine, PseudoephedrineSemprex D
How Acrivastine, Pseudoephedrine interacts with Activated Charcoal 520 mg — through 1 ingredient. Tap an ingredient for the detail:
Activated CharcoalOral Drugs Major
Interaction Summary
Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.
Read the full Activated Charcoal + Acrivastine, Pseudoephedrine interactionAcyclovirAvaclyr, Sitavig, Zovirax, Zovirax Injection
How Acyclovir interacts with Activated Charcoal 520 mg — through 1 ingredient. Tap an ingredient for the detail:
Activated CharcoalOral Drugs Major
Interaction Summary
Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.
Read the full Activated Charcoal + Acyclovir interactionAdagrasibKrazati
How Adagrasib interacts with Activated Charcoal 520 mg — through 1 ingredient. Tap an ingredient for the detail:
Activated CharcoalOral Drugs Major
Interaction Summary
Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.
Read the full Activated Charcoal + Adagrasib interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Activated Charcoal 520 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Activated Charcoal
Oral Drugs
Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.
Activated charcoal adsorbs various drugs and may reduce their absorption and/or half-life. Examples of affected drugs include acetaminophen, aminophylline, amiodarone, atenolol, carbamazepine, dapsone, digoxin, disopyramide, fluoxetine, indomethacin, moxifloxacin, nadolol, phenytoin, phenobarbital, piroxicam, quinine, sotalol, theophylline, tricyclic antidepressants, valproate, and verapamil. Avoid co-administration, except after drug overdose.
Alcohol (Ethanol)
The binding action of activated charcoal may be reduced by alcohol.
Alcohol may lower the adsorptive capacity of activated charcoal.
Contraceptive Drugs
Activated charcoal may reduce the clinical effects of oral contraceptives.
Activated charcoal, taken in a dose of 5 grams four times daily for 3 days, may bind to, and reduce the absorption of, oral contraceptives, thereby limiting their effectiveness and increasing the risk of contraceptive failure. However, some clinical research shows that the risk for this interaction is minimal when activated charcoal is taken either 3 hours after or at least 12 hours before oral contraceptives.
Brand information
Manufacturer and brand details for Activated Charcoal 520 mg, from the product label.
GNC
See all GNC products- Name
- General Nutrition Corporation
- City
- Pittsburgh
- State
- PA
- ZipCode
- 15222
- Phone Number
- 1-888-462-2548
- Web Address
- gnc.com
Activated Charcoal 520 mg by GNC: Common Questions
Does Activated Charcoal 520 mg by GNC interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Will this interfere with my prescription medications?
Can I take activated charcoal if I'm on birth control pills?
What side effects should I expect?
Is it safe to use if I'm pregnant?
What is activated charcoal used for?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Activated Charcoal 520 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Activated Charcoal 520 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Activated Charcoal 520 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 14 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Activated Charcoal 14 references
- Kaaja RJ, Kontula KK, Raiha A, Laatikainen T. Treatment of cholestasis of pregnancy with peroral activated charcoal. A preliminary study. Scand J Gastroenterol 1994;29:178-81.
- Anon. Position statement and practice guidelines on the use of multi-dose activated charcoal in the treatment of acute poisoning. American Academy of Clinical Toxicology; European Association of Poisons Centres and Clinical Toxicologists. J Toxicol Clin T
- Park GD, Spector R, Kitt TM. Superactivated charcoal versus cholestyramine for cholesterol lowering: a randomized cross-over trial. J Clin Pharmacol 1988;28:416-9. PubMed
- Hoegberg LC, Angelo HR, Christophersen AB, Christensen HR. Effect of ethanol and pH on the adsorption of acetaminophen (paracetamol) to high surface activated charcoal, in vitro studies. J Toxicol Clin Toxicol 2002;40:59-67. PubMed
- Brahmi N, Kouraichi N, Thabet H, Amamou M. Influence of activated charcoal on the pharmacokinetics and the clinical features of carbamazepine poisoning. Am J Emerg Med 2006;24(4):440-3. PubMed
- Gude AB, Hoegberg LC, Angelo HR, Christensen HR. Dose-dependent adsorptive capacity of activated charcoal for gastrointestinal decontamination of a simulated paracetamol overdose in human volunteers. Basic Clin Pharmacol Toxicol 2010;106(5)406-10. PubMed
- Wananukul W, Klaikleun S, Sriapha C, Tongpoo A. Effect of activated charcoal in reducing paracetamol absorption at supra-therapeutic dose. J Med Assoc Thai 2010;93(10):1145-9.
- Wang Z, Cui M, Tang L, et al. Oral activated charcoal suppresses hyperphosphataemia in haemodialysis patients. Nephrology (Carlton) 2012;17(7):616-20. PubMed
- Wang X, Mondal S, Wang J, et al. Effect of activated charcoal on apixaban pharmacokinetics in healthy subjects. Am J Cardiovasc Drugs 2014;14(2):147-54. PubMed
- Chyka PA, Seger D, Krenzelok EP, et al. Position paper: single-dose activated charcoal. Clin Toxicol (Phila) 2005;43(2):61-87. PubMed
- Chiew AL, Gluud C, Brok J, Buckley NA. Interventions for paracetamol (acetaminophen) overdose. Cochrane Database Syst Rev 2018;2:CD003328. PubMed
- Elomaa K, Ranta S, Tuominen J, Lähteenmäki P. Charcoal treatment and risk of escape ovulation in oral contraceptive users. Hum Reprod. 2001;16(1):76-81. PubMed
- Gao Y, Wang G, Li Y, Lv C, Wang Z. Effects of oral activated charcoal on hyperphosphatemia and vascular calcification in Chinese patients with stage 3-4 chronic kidney disease. J Nephrol. 2019;32(2):265-72. PubMed
- Skov K, Graudal NA, Jürgens G. The effect of activated charcoal on drug exposure following intravenous administration: A meta-analysis. Basic Clin Pharmacol Toxicol 2021;128(4):568-578. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC