No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Lecithin 500 Ingredients & Drug Interactions

by GNC

Lecithin 500 label
See full label image
Softgel Capsule Category: Fat/fatty Acid
No known interaction
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Lecithin 500 against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line No known interaction

Lecithin 500 is a dietary supplement by GNC with 1 active ingredient. Its ingredients are commonly taken for high cholesterol, liver health, brain and memory support.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

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HelloPharmacist Scorecard of Lecithin 500 by GNC

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 13, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Lecithin 500 contains one active ingredient: lecithin, a fatty substance found in plants and animals that plays a role in cell structure and function. Each softgel delivers 500 mg of this compound.

There are no inactive ingredients listed for this product.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Lecithin's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: support for cardiovascular and nervous system health.
  • We looked for evidence on: Hyperlipidemia, Dry skin, liver function, brain health.
  • The closest evidence on file: Lecithin is rated "Insufficient Reliable Evidence To Rate" for Dry skin (Natural Medicines).
  • Also on file: Lecithin is rated "Insufficient Reliable Evidence To Rate" for Hyperlipidemia.

The evidence for lecithin's effectiveness is mixed. It's considered likely ineffective for Alzheimer disease.

For age-related cognitive decline, anxiety, bipolar disorder, and TPN-associated hepatic steatosis (a liver condition that can happen with long-term IV nutrition), the evidence is insufficient — meaning we don't have enough reliable data to know whether it works. Lecithin is sometimes used to help with clogged milk ducts during breastfeeding, but you should check with your healthcare provider before using it for that purpose.

The evidence, ingredient by ingredient Lecithin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lecithin is generally considered safe for most people in food and supplement amounts. When taken by mouth, it's well tolerated overall.

The most common side effects are abdominal pain, diarrhea, fullness, and nausea — though not everyone experiences them. If you have an egg or soy allergy, lecithin can trigger allergic skin reactions, so it's worth being aware of that.

Pregnancy and lactation: lecithin is rated likely safe during both.

Side effects, ingredient by ingredient Lecithin

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for lecithin. Still, before you start any new supplement, it's smart to mention it to your own doctor or pharmacist, especially if you take multiple medications or have food allergies.

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. No medication interactions are currently documented, and safety information is well characterized.

Lecithin 500 is a straightforward single-ingredient supplement with no documented medication interactions. It's generally well tolerated, though it may cause digestive upset in some people.

Evidence for its effectiveness is limited or insufficient for most claimed uses. If you're considering it for a specific health concern — especially clogged milk ducts or cognitive issues — talk it over with your doctor or pharmacist first to see if it's the right fit for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 1, 2012.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Lecithin 500, straight from the product label.

Brand GNC
Net contents 100 Softgel Capsule(s)
Market status On market
Date entered into DSLD Oct 1, 2012
DSLD ID 13260
Product type Fat/fatty Acid
Supplement form Softgel Capsule
Dietary claims / uses Nutrient
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Lecithin 500 by GNC, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel Capsule(s)
Maximum serving Sizes:
1 Softgel Capsule(s)
IngredientAmount% DV
Lecithin500 mg--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Lecithin is a natural edible oil that offers many benefits: It may help the body to emulsify fat Provides dietary support for a healthy cardiovascular system Provides support for a healthy nervous system function Provides dietary support for a healthy liver Helps support normal choline levels during exercise

optimized

FDA Statement of Identity

DIETARY SUPPLEMENT

Brand IP Statement(s)

Copyright (C) 2011 GNC All Rights Reserved. Do not republish contents.

Formula

Derived from soybeans. Each serving contains 500 mg of Lecithin. Enhanced with Vitamin E to help preserve the freshness and potency of each soft gel capsule.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Lecithin 500 by GNC label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Lecithin 500 label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Lecithin 500 by GNC

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Softgel Capsule(s) Dosage formSoftgel Capsule Amounts shown are per serving.

Lecithin

No known
interactions
500 mg per serving

Lecithin is a natural fatty substance found in foods and made by the body that is widely used as a supplement and food emulsifier. Evidence supporting...

Lecithin monograph & interactions
Interaction report

Lecithin 500 by GNC Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Lecithin 500. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Lecithin 500, from the product label.

GNC

See all GNC products
Name
GNC
Pharmacist Counseling Corner

Lecithin 500 by GNC: Common Questions

Does Lecithin 500 by GNC interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Lecithin 500. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Lecithin 500 contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will lecithin interact with my medications?
No interactions are documented in our data for lecithin. That said, absence of documented interactions isn't an iron-clad guarantee none exist. Run your exact medications through the checker on this page, or confirm with your pharmacist or doctor before you start.
What are the most common side effects?
When taken by mouth, lecithin most often causes abdominal pain, diarrhea, fullness, and nausea — though not everyone gets them. If you have an egg or soy allergy, you may also develop allergic skin reactions.
Is it safe during pregnancy or breastfeeding?
Lecithin is rated likely safe in pregnancy and lactation. Lecithin is often used to help with clogged milk ducts, but talk with your healthcare provider before using supplements, especially during breastfeeding.
Does lecithin actually work for memory or Alzheimer disease?
For Alzheimer disease, lecithin is considered likely ineffective. For age-related cognitive decline, we don't have enough reliable evidence to say whether it works. If memory concerns are on your mind, talk with your doctor about what's actually supported.
What exactly is lecithin?
Lecithin is a fatty substance found naturally in plants and animals. It's a structural component of cell membranes and is involved in how cells function — that's why it shows up in food and supplements.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Lecithin 500 is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Lecithin 500 label
Go deeper

The Full Monographs Behind Lecithin 500’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Lecithin

Lecithin is a natural fatty substance found in foods and made by the body that is widely used as a supplement and food emulsifier. Evidence supporting most of its health claims is limited, t...

Read the full Lecithin monograph →
Sources

Sources & How We Checked

Lecithin 500's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 9 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lecithin 9 references
  1. Buchman AL, Dubin M, Jenden D, et al. Lecithin increases plasma free choline and decreases hepatic steatosis in long-term total parenteral nutrition patients. Gastroenterology 1992;102:1363-70.
  2. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
  3. Chatellier G, Lacomblez L. Tacrine (tetrahydroaminoacridine; THA) and lecithin in senile dementia of the Alzheimer type: a multicentre trial. Groupe Francais d'Etude de la Tetrahydroaminoacridine. BMJ 1990;300:495-9.
  4. Gelenberg AJ, Dorer DJ, Wojcik JD, et al. A crossover study of lecithin treatment of tardive dyskinesia. J Clin Psychiatry 1990;51:149-53.
  5. Little A, Levy R, Chuaqui-Kidd P, Hand D. A double-blind, placebo controlled trial of high-dose lecithin in Alzheimer's disease. J Neurol Neurosurg Psychiatry 1985;48:736-42. PubMed
  6. Palm M, Moneret-Vautrin DA, Kanny G, et al. Food allergy to egg and soy lecithins. Allergy 1999;54:1116-7. PubMed
  7. Drachman DA, Glosser G, Fleming P, et al. Memory decline in the aged: treatment with lecithin and physostigmine. Neurology 1982;32:944-50. PubMed
  8. Gelenberg, A. J., Doller-Wojcik, J. C., and Growdon, J. H. Choline and lecithin in the treatment of tardive dyskinesia: preliminary results from a pilot study. Am J Psychiatry 1979;136(6):772-776. PubMed
  9. Electronic Code of Federal Regulations. Title 21, Chapter 1, Subchapter B, Part 184: Direct food substances affirmed as Generally Recognized as Safe. Subpart B - listing of specific substances affirmed as GRAS. Sec. 184.1400 Lecithin. Available at: https:

See these in context on the Lecithin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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