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Dietary supplement

Activated Charcoal Capsules 260 mg (4 gr) Ingredients & Drug Interactions

by Puritan's Pride Premium

Activated Charcoal Capsules 260 mg (4 gr) label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Activated Charcoal Capsules 260 mg (4 gr) against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Activated Charcoal Capsules 260 mg (4 gr) is a dietary supplement by Puritan's Pride Premium with 1 active ingredient. Its ingredients are commonly taken for poisoning and drug overdose (in emergency care), gas and bloating, upset stomach.Based on those ingredients, 2,027 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Activated Charcoal. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Activated Charcoal Capsules 260 mg (4 gr) by Puritan's Pride Premium

Ask about any prescription or over-the-counter medication and we check it for interactions with Activated Charcoal Capsules 260 mg (4 gr) by Puritan's Pride Premium — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Activated Charcoal Capsules 260 mg (4 gr) by Puritan's Pride Premium

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 12, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains 1 active ingredient: activated charcoal, a highly porous form of carbon that works by binding to substances in your digestive tract. The capsule itself is made from gelatin, with magnesium stearate added as a binder.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Absorb a variety of substances.
  • We looked for evidence on: Poisoning, Flatulence, Dyspepsia, Gas and bloating, Upset stomach, General detoxification.
  • The strongest evidence on file: Activated Charcoal is rated "Possibly Effective" for Poisoning (Natural Medicines).
  • Also on file: Activated Charcoal is rated "Insufficient Reliable Evidence To Rate" for Dyspepsia, Flatulence.

Activated charcoal is rated possibly effective for poisoning (likely acute overdose situations). For other common uses like lowering cholesterol, reducing gas, easing upset stomach, or treating hangovers, the evidence we hold is insufficient — meaning either the studies are too small or too few, or the science just isn't settled yet.

Talk to your pharmacist about what you're hoping it will do.

The evidence, ingredient by ingredient Activated Charcoal

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Activated charcoal is generally well tolerated for short-term use. The most common side effects are gastrointestinal — constipation is the most frequent complaint, though usually temporary, and black stools, belly pain, bloating, and gas have been reported.

Rarely, it can cause a blockage in your intestines. Because it reduces absorption of many things, long-term routine use isn't well studied.

In pregnancy, there isn't enough data to know whether it's safe; use it only under medical guidance. If you're breastfeeding, check with your doctor or pharmacist before starting.

Side effects, ingredient by ingredient Activated Charcoal

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Activated Charcoal.
  • The most serious interaction on file is rated Major.
  • For scale: 2,028 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check all oral medications before taking this product — activated charcoal reduces how much of many drugs your body absorbs (Major severity). Also double-check if you take birth control pills (Moderate) or drink alcohol regularly (Moderate).

Use the search tool on this page with your exact medications, then talk to your pharmacist about when and how to take this safely.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Major medication interactions have been identified, and safety information is well characterized.

Activated charcoal may be worth considering for acute poisoning situations under medical care, but it's not a proven remedy for everyday digestive complaints. If you take any prescription or over-the-counter medications — especially birth control, heart drugs, or seizure drugs — you need to talk to your pharmacist first.

The key is timing: charcoal can block absorption of almost anything in your gut, so it has to be dosed far apart from your other medicines.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 22, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Activated Charcoal Capsules 260 mg (4 gr), straight from the product label.

Brand Puritan's Pride Premium
Barcode (UPC) 074312136801
Net contents 100 Rapid Release Capsule(s)
Market status On market
Date entered into DSLD Jun 22, 2023
DSLD ID 286354
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Activated Charcoal Capsules 260 mg (4 gr) by Puritan's Pride Premium, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
50
UPC/BARCODE
074312136801
IngredientAmount% DV
Activated Charcoal520 mg--

Other ingredients: Gelatin, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Traditionally used to absorb a variety of substances

Activated charcoal is an insoluble black fiber traditionally used to absorb a variety of substances.

No artificial color, flavor or sweetener, no preservatives, no sugar, no starch, no milk, no lactose, no soy, no gluten.

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: For adults, take two (2) capsules after meals if needed.

Any medication should be taken one (1) hour prior to consuming this product.

General Statements

Puritan's Pride supplements are produced from the finest raw materials under stringent quality control standards. State-of-the-art manufacturing and packaging facilities ensure you the highest quality nutritional supplements money can buy. When it comes to your health...choose the best.

To reorder item #3680 www.puritan.com 1-800-645-1030

Precautions

Warning: If you are pregnant, nursing, taking any medications or have any medical condition, consult your doctor before use.

Discontinue use and consult your doctor if any adverse reactions occur.

Keep out of reach of children.

Do not use if seal under cap is broken or missing.

Storage

Store at room temperature.

Brand IP Statement(s)

Copyright 2013 Puritan's Pride, Inc.

Seals/Symbols

QA Quality Assured

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Activated Charcoal Capsules 260 mg (4 gr) by Puritan's Pride Premium label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Activated Charcoal Capsules 260 mg (4 gr) label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Activated Charcoal Capsules 260 mg (4 gr) by Puritan's Pride Premium

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container50 Amounts shown are per serving.

Activated Charcoal

Interacts with
2,027 drugs
520 mg per serving

Activated charcoal is a highly porous form of carbon that can bind certain substances in the gut, and it is used in hospitals to treat some poisonings...

Activated Charcoal monograph & interactions

Other (inactive) ingredients: Gelatin, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Activated Charcoal Capsules 260 mg (4 gr) by Puritan's Pride Premium Drug Interactions

Want to check YOUR meds against Activated Charcoal Capsules 260 mg (4 gr)?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
2,027Drugs
2,022 Major 5 Moderate

Ingredients driving the most interactions

Activated Charcoal 2,027

Individual Drug Interactions

The ingredients in Activated Charcoal Capsules 260 mg (4 gr) interact with 2,027 drugs. Click any drug to see the details.

1 of the 1 ingredient in Activated Charcoal Capsules 260 mg (4 gr) interact with drugs. Each result below shows which ingredient is responsible. Activated Charcoal

Each ingredient & the kinds of drugs it affects

For each ingredient in Activated Charcoal Capsules 260 mg (4 gr) with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Activated Charcoal3 drug types · 2,027 drugs

Oral Drugs

Activated charcoal reduces systemic exposure to many drugs, including those that undergo enterohepatic recirculation, regardless of the route of administration.
Activated charcoal adsorbs various drugs and may reduce their absorption and/or half-life. Examples of affected drugs include acetaminophen, aminophylline, amiodarone, atenolol, carbamazepine, dapsone, digoxin, disopyramide, fluoxetine, indomethacin, moxifloxacin, nadolol, phenytoin, phenobarbital, piroxicam, quinine, sotalol, theophylline, tricyclic antidepressants, valproate, and verapamil. Avoid co-administration, except after drug overdose.

Likelihood Probable Evidence B
Alcohol (Ethanol)

The binding action of activated charcoal may be reduced by alcohol.
Alcohol may lower the adsorptive capacity of activated charcoal.

Likelihood Probable Evidence D
Contraceptive Drugs

Activated charcoal may reduce the clinical effects of oral contraceptives.
Activated charcoal, taken in a dose of 5 grams four times daily for 3 days, may bind to, and reduce the absorption of, oral contraceptives, thereby limiting their effectiveness and increasing the risk of contraceptive failure. However, some clinical research shows that the risk for this interaction is minimal when activated charcoal is taken either 3 hours after or at least 12 hours before oral contraceptives.

Likelihood Possible Evidence B
Activated Charcoal full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Activated Charcoal Capsules 260 mg (4 gr), from the product label.

Puritan's Pride Premium

See all Puritan's Pride Premium products
Name
Puritan's Pride, Inc.
City
Holbrook
State
NY
ZipCode
11741
Phone Number
1-800-645-1030
Web Address
www.puritan.com
Pharmacist Counseling Corner

Activated Charcoal Capsules 260 mg (4 gr) by Puritan's Pride Premium: Common Questions

Does Activated Charcoal Capsules 260 mg (4 gr) by Puritan's Pride Premium interact with any medications?
Yes. Based on its ingredients, Activated Charcoal Capsules 260 mg (4 gr) has a known interaction with 2,027 medications, including 2022 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Activated Charcoal Capsules 260 mg (4 gr) contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is activated charcoal, and how does it work?
Activated charcoal is a highly porous form of carbon that binds to substances in your digestive tract. It's most commonly used in acute poisoning situations to prevent absorption of the poison, but people also use it for other digestive complaints — though evidence for those uses isn't well established yet.
Will this interfere with my medications?
Yes — activated charcoal can reduce absorption of many oral drugs, including common heart, blood-pressure, and seizure medications. It may also weaken birth control pills. You need to check your exact medications using the tool on this page and talk to your pharmacist about timing before you start.
What are the side effects?
The most common are constipation (usually temporary), black stools, belly pain, bloating, and gas. Rarely, it can cause a blockage in your intestines. Because it binds so many things, long-term everyday use isn't well studied.
Is it safe to take during pregnancy or while breastfeeding?
There isn't enough data to know whether it's safe in pregnancy — use it only under medical guidance. For breastfeeding, there's also very little safety information, so check with your doctor or pharmacist for personalized advice before starting.
Can I take this for a hangover or to lower cholesterol?
The evidence we hold for those uses is insufficient — the studies either aren't robust enough or don't exist yet. If that's what you're considering it for, talk to your pharmacist about whether it makes sense for you.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Activated Charcoal Capsules 260 mg (4 gr) is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Activated Charcoal Capsules 260 mg (4 gr) label
Go deeper

The Full Monographs Behind Activated Charcoal Capsules 260 mg (4 gr)’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Activated Charcoal

Interacts with 2,027 drugs

Activated charcoal is a highly porous form of carbon that can bind certain substances in the gut, and it is used in hospitals to treat some poisonings and overdoses. For everyday uses like g...

Read the full Activated Charcoal monograph →
Sources

Sources & How We Checked

Activated Charcoal Capsules 260 mg (4 gr)'s label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 14 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Activated Charcoal 14 references
  1. Kaaja RJ, Kontula KK, Raiha A, Laatikainen T. Treatment of cholestasis of pregnancy with peroral activated charcoal. A preliminary study. Scand J Gastroenterol 1994;29:178-81.
  2. Anon. Position statement and practice guidelines on the use of multi-dose activated charcoal in the treatment of acute poisoning. American Academy of Clinical Toxicology; European Association of Poisons Centres and Clinical Toxicologists. J Toxicol Clin T
  3. Park GD, Spector R, Kitt TM. Superactivated charcoal versus cholestyramine for cholesterol lowering: a randomized cross-over trial. J Clin Pharmacol 1988;28:416-9. PubMed
  4. Hoegberg LC, Angelo HR, Christophersen AB, Christensen HR. Effect of ethanol and pH on the adsorption of acetaminophen (paracetamol) to high surface activated charcoal, in vitro studies. J Toxicol Clin Toxicol 2002;40:59-67. PubMed
  5. Brahmi N, Kouraichi N, Thabet H, Amamou M. Influence of activated charcoal on the pharmacokinetics and the clinical features of carbamazepine poisoning. Am J Emerg Med 2006;24(4):440-3. PubMed
  6. Gude AB, Hoegberg LC, Angelo HR, Christensen HR. Dose-dependent adsorptive capacity of activated charcoal for gastrointestinal decontamination of a simulated paracetamol overdose in human volunteers. Basic Clin Pharmacol Toxicol 2010;106(5)406-10. PubMed
  7. Wananukul W, Klaikleun S, Sriapha C, Tongpoo A. Effect of activated charcoal in reducing paracetamol absorption at supra-therapeutic dose. J Med Assoc Thai 2010;93(10):1145-9.
  8. Wang Z, Cui M, Tang L, et al. Oral activated charcoal suppresses hyperphosphataemia in haemodialysis patients. Nephrology (Carlton) 2012;17(7):616-20. PubMed
  9. Wang X, Mondal S, Wang J, et al. Effect of activated charcoal on apixaban pharmacokinetics in healthy subjects. Am J Cardiovasc Drugs 2014;14(2):147-54. PubMed
  10. Chyka PA, Seger D, Krenzelok EP, et al. Position paper: single-dose activated charcoal. Clin Toxicol (Phila) 2005;43(2):61-87. PubMed
  11. Chiew AL, Gluud C, Brok J, Buckley NA. Interventions for paracetamol (acetaminophen) overdose. Cochrane Database Syst Rev 2018;2:CD003328. PubMed
  12. Elomaa K, Ranta S, Tuominen J, Lähteenmäki P. Charcoal treatment and risk of escape ovulation in oral contraceptive users. Hum Reprod. 2001;16(1):76-81. PubMed
  13. Gao Y, Wang G, Li Y, Lv C, Wang Z. Effects of oral activated charcoal on hyperphosphatemia and vascular calcification in Chinese patients with stage 3-4 chronic kidney disease. J Nephrol. 2019;32(2):265-72. PubMed
  14. Skov K, Graudal NA, Jürgens G. The effect of activated charcoal on drug exposure following intravenous administration: A meta-analysis. Basic Clin Pharmacol Toxicol 2021;128(4):568-578. PubMed

See these in context on the Activated Charcoal monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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