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Dietary supplement

Alpha GPC 325 mg Ingredients & Drug Interactions

by VitaMonk

Alpha GPC 325 mg label
See full label image
Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Minor
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Alpha GPC 325 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Minor

Alpha GPC 325 mg is a dietary supplement by VitaMonk with 1 active ingredient. Its ingredients are commonly taken for memory and learning support, age-related cognitive decline, alzheimer's disease and dementia (under study).Based on those ingredients, 16 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are Alpha GPC. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Alpha GPC 325 mg by VitaMonk

Ask about any prescription or over-the-counter medication and we check it for interactions with Alpha GPC 325 mg by VitaMonk — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Alpha GPC 325 mg by VitaMonk

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 16, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: Alpha-GPC at 325 mg per capsule. Alpha-GPC is a compound that supplies choline, a building block your brain uses to support nerve cell function and communication.

The capsule also contains inactive ingredients — vegetable cellulose, rice flour, and rice concentrate — which are fillers and binders.

Does it work?

Insufficient evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Insufficient

There isn't enough reliable clinical evidence to rate this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: supports brain cognition and promotes learning memory.
  • We looked for evidence on: Cognitive function, Memory, Learning, Age-related cognitive decline.
  • The closest evidence on file: Alpha-gpc is rated "Insufficient Reliable Evidence To Rate" for Cognitive function (Natural Medicines).

The evidence for Alpha-GPC is mixed. It's rated possibly effective for Alzheimer disease, meaning there's some research support but it's not conclusive.

For cognitive function, brain tumor, vascular dementia, and stroke, the evidence isn't yet reliable enough to rate — we don't have solid proof it works for those uses. If you're considering this for a specific condition, talk it over with your doctor about what the research actually shows for your situation.

The evidence, ingredient by ingredient Alpha-gpc

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Alpha-GPC is generally well tolerated in studies, though long-term safety hasn't been fully established. Serious side effects are rare, but there is one concern worth knowing: oral use for at least 2 months has been rarely associated with an elevated risk of stroke compared with non-users or shorter-term users.

More common minor side effects — reported rarely — include dizziness, headache, insomnia, nausea, vomiting, diarrhea, and heartburn. Because safety data in pregnancy and lactation isn't on file, talk with your doctor or pharmacist before taking this if you're pregnant, planning to become pregnant, or breastfeeding.

Side effects, ingredient by ingredient Alpha-gpc

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Alpha-gpc.
  • The most serious interaction on file is rated Minor.
  • For scale: 16 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you start, check with your doctor or pharmacist if you take scopolamine (Transderm Scop) for motion sickness — Alpha-GPC may weaken its effects.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with insufficient evidence for its stated purpose. Only minor medication interactions are documented, and safety information is well characterized.

Alpha-GPC may help support brain function, with the strongest evidence for Alzheimer disease, though the research isn't definitive. If you take a scopolamine motion sickness patch, check with your doctor or pharmacist first — this supplement might reduce how well it works.

Given the rare but documented stroke risk with longer-term use and incomplete long-term safety data, discuss whether this is right for you with your own healthcare provider.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Feb 25, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Alpha GPC 325 mg, straight from the product label.

Brand VitaMonk
Barcode (UPC) B01K13ACDA
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Feb 25, 2021
DSLD ID 242101
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Alpha GPC 325 mg by VitaMonk, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
60
UPC/BARCODE
B01K13ACDA
IngredientAmount% DV
Alpha GPC325 mg--

Other ingredients: Vegetable Cellulose, Rice Flour, Rice concentrate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions & Recommended Use: As a dietary supplement, take one to two capsules daily or as directed by your healthcare practitioner.

Precautions

Warning: Keep out of reach from children. Do not use if pregnant, nursing or under the age of 18.

Do not use if pregnant, nursing or under the age of 18.

Consult with a healthcare professional if you have or suspect a medical condition, or before beginning any new dietary supplement. If you experience any adverse reactions please discontinue use and contact your health care professional. Do not use if safety seal is damaged or missing.

Storage

Store in a cool, dry place.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration This product is not intended to diagnose, treat, cure or prevent any disease.

Seals/Symbols

GMP Good Manufacturing Practice 100% Premium Quality Satisfaction Guaranteed

Formulation

Supports brain cognition Promotes learning and memory

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Alpha GPC 325 mg by VitaMonk label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Alpha GPC 325 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Alpha GPC 325 mg by VitaMonk

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Alpha GPC

Interacts with
16 drugs
325 mg per serving

Alpha-GPC is a choline-containing compound used mainly for memory, brain health, and as a choline source. There is some evidence it may help cognition...

Alpha GPC monograph & interactions

Other (inactive) ingredients: Vegetable Cellulose, Rice Flour, Rice concentrate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Alpha GPC 325 mg by VitaMonk Drug Interactions

Want to check YOUR meds against Alpha GPC 325 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
16Drugs
16 Minor

Ingredients driving the most interactions

Alpha GPC 16

Individual Drug Interactions

The ingredients in Alpha GPC 325 mg interact with 16 drugs. Click any drug to see the details.

1 of the 1 ingredient in Alpha GPC 325 mg interact with drugs. Each result below shows which ingredient is responsible. Alpha GPC

Each ingredient & the kinds of drugs it affects

For each ingredient in Alpha GPC 325 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Alpha GPC1 drug type · 16 drugs

Scopolamine (Transderm Scop)

Theoretically, alpha-GPC might decrease the effects of scopolamine.
A small clinical study shows that alpha-GPC can partially counteract the attention and memory impairment effects caused by scopolamine given intramuscularly. Whether alpha-GPC can decrease the beneficial anti-motion sickness effects of the scopolamine patch (Transderm Scop) is unclear.

Likelihood Possible Evidence B
Alpha GPC full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Alpha GPC 325 mg, from the product label.

VitaMonk

See all VitaMonk products
Name
VitaMonk
Street Address
2637 E Atlantic Blvd #24351
City
Pompano Beach
State
FL
ZipCode
33062
Web Address
VitaMonk.com
Pharmacist Counseling Corner

Alpha GPC 325 mg by VitaMonk: Common Questions

Does Alpha GPC 325 mg by VitaMonk interact with any medications?
Yes. Based on its ingredients, Alpha GPC 325 mg has a known interaction with 16 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Alpha GPC 325 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is Alpha-GPC and what's it supposed to do?
Alpha-GPC is a compound that provides choline, which your brain uses to build and maintain nerve cells and support how they communicate with each other. The research is strongest for Alzheimer disease, where it's possibly effective, but evidence for other brain-related uses like general cognitive function isn't solid yet.
Is Alpha-GPC safe to take long-term?
Alpha-GPC is generally well tolerated in short-term studies, but long-term safety hasn't been fully established. One thing to note: taking it for at least 2 months has been rarely linked to a higher stroke risk compared with people who don't use it or use it for shorter periods. Talk with your doctor about whether long-term use is right for you.
What side effects might I experience?
Most people don't experience side effects, but rare ones include dizziness, headache, insomnia, nausea, vomiting, diarrhea, and heartburn. Serious effects are uncommon. If you notice anything unusual, tell your pharmacist or doctor.
Can I take this if I'm pregnant or breastfeeding?
There isn't enough safety information on file for pregnancy or lactation. Talk with your doctor or pharmacist for personalized advice before taking this if you're pregnant, planning to become pregnant, or breastfeeding.
Does this product have any fillers or extra ingredients I should know about?
Yes — the capsule contains inactive ingredients: vegetable cellulose, rice flour, and rice concentrate. These are binders and fillers that help hold the supplement together, not active ingredients.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Alpha GPC 325 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Alpha GPC 325 mg label
Go deeper

The Full Monographs Behind Alpha GPC 325 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Alpha-gpc

Interacts with 16 drugs

Alpha-GPC is a choline-containing compound used mainly for memory, brain health, and as a choline source. There is some evidence it may help cognition in people with dementia, but evidence i...

Read the full Alpha-gpc monograph →
Sources

Sources & How We Checked

Alpha GPC 325 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 4 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Alpha-gpc 4 references
  1. Di Perri R, Coppola G, Ambrosio LA, et al. A multicentre trial to the evaluate the efficacy and tolerability of alpha-glycerylphosphorylcholine versus cytosine diphosphocholine in patients with vascular dementia. J Int Med Res 1991;19:330-41.
  2. Barbagallo Sangiorgi G, Barbagallo M, Giordano M, et al. Alpha-glycerophosphocholine in the mental recovery of cerebral ischemic attacks: An Italian multicenter clinical trial. Ann N Y Acad Sci 1994;717:253-69. PubMed
  3. Canal N, Franceschi M, Alberoni M, et al. Effect of L-alpha-glyceryl-phosphorylcholine on amnesia caused by scopolamine. Int J Clin Pharmacol Ther Toxicol 1991;29:103-7.
  4. Lee G, Choi S, Chang J, et al. Association of L-a glycerylphosphorylcholine with subsequent stroke risk after 10 Years. JAMA Netw Open 2021;4(11):e2136008.

See these in context on the Alpha-gpc monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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