American Saffron & Slippery Elm Vanilla Flavor Ingredients & Drug Interactions
by TerraVita
What is this page for?
First and foremost: checking American Saffron & Slippery Elm Vanilla Flavor against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
American Saffron & Slippery Elm Vanilla Flavor is a dietary supplement by TerraVita with 1 active ingredient. Its ingredients are commonly taken for heart and cholesterol support, skin moisturizing, menstrual cramps.Based on those ingredients, 2,068 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are American Saffron and Slippery Elm Glycerite Liquid Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against American Saffron & Slippery Elm Vanilla Flavor by TerraVita
Ask about any prescription or over-the-counter medication and we check it for interactions with American Saffron & Slippery Elm Vanilla Flavor by TerraVita — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of American Saffron & Slippery Elm Vanilla Flavor by TerraVita
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
This liquid contains 2 active ingredients: American Saffron (safflower) and Slippery Elm, each as a glycerite liquid extract. Glycerite extracts are made by soaking the plant material in glycerin, a natural preservative and sweetener.
The product also contains glycerin and vanilla flavor as inactive ingredients.
Does it work?
Couldn't assess
The evidence we hold does not establish that safflower works for unstable angina, coronary heart disease, cystic fibrosis, diabetes, or diabetic kidney disease — the available studies are not reliable enough to rate it. Slippery elm's effectiveness for cancer, constipation, cough, inflammatory bowel disease, or diarrhea is also not established in our data.
If you're thinking about this product for a specific reason, ask your pharmacist whether there's evidence behind that use.
How safe is it?
Well-documented data
Safflower oil in food amounts is generally well tolerated, but concentrated flower extracts and high-dose supplements have less safety information. There are at least 7 case reports linking safflower supplements (usually taken for weight loss) to acute liver failure requiring transplant, though the exact doses or how long people took it are unclear.
Slippery elm is generally well tolerated for short-term use, but long-term safety data are limited. Slippery elm pollen and bark extracts can trigger contact dermatitis, hives, or allergic reactions in some people.
For pregnancy, safflower is rated with conflicting evidence (ranging from Likely Safe to Likely Unsafe), and the safety data advises against medicinal amounts during pregnancy since safflower has traditionally been used to bring on menstruation. For breastfeeding, there isn't enough reliable information on either ingredient to know whether they're safe beyond normal food use.
Meds to double-check
Moderate interaction found
Check with your pharmacist before using this product if you take blood thinners (anticoagulants) or warfarin — safflower may increase bleeding risk. Also double-check if you take diabetes drugs, since safflower may interfere with blood sugar control.
Because slippery elm may slow the absorption of oral medications in general, space out when you take this product and your other swallowed drugs by at least 2 hours if you can.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
This product might interest someone looking for a traditional herbal remedy, but because safflower can raise bleeding risk with blood thinners and may affect blood sugar control, and because slippery elm may slow how your body absorbs other oral drugs, you should check your medications with your pharmacist before starting. If you're pregnant or breastfeeding, talk to your doctor or pharmacist first.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Dec 13, 2022.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about American Saffron & Slippery Elm Vanilla Flavor, straight from the product label.
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for American Saffron & Slippery Elm Vanilla Flavor by TerraVita, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| American Saffron and Slippery Elm Glycerite Liquid Extract | 0.13 mL | -- |
| American Saffron Glycerite Liquid Extract | 0 NP | -- |
| Slippery Elm Glycerite Liquid Extract | 0 NP | -- |
Other ingredients: Glycerin, Vanilla flavor
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)
Copyright 2018 TerraVita - Distributed by ZooScape LLC, All Rights Reserved.
Formula
Glycerite liquid extract (1:5)
Formulation
Alcohol free
Suggested/Recommended/Usage/Directions
Suggested Use: Take 25-40 drops of extract in a small amount of warm water 3-4 times daily. Shake well before using.
Precautions
Keep away from children.
Do not use if safety seal around cap is broken or missing.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
American Saffron & Slippery Elm Vanilla Flavor by TerraVita label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in American Saffron & Slippery Elm Vanilla Flavor by TerraVita
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size25 Drop(s) Dosage formLiquid Servings per container227 Amounts shown are per serving.
American Saffron and Slippery Elm Glycerite Liquid Extract
Interacts with208 drugs
Safflower is a thistle-like plant used mainly for its seed oil (a common cooking oil) and its colorful flowers. Safflower oil is a reasonable source o...
American Saffron and Slippery Elm Glycerite Liquid Extract monograph & interactionsOther (inactive) ingredients: Glycerin, Vanilla flavor. These complete the product’s ingredient list but are not active constituents.
American Saffron & Slippery Elm Vanilla Flavor by TerraVita Drug Interactions
HelloPharmacist Interaction Report
American Saffron & Slippery Elm Vanilla Flavor by TerraVita contains two active ingredients, each with documented interactions.
The most serious concern is safflower (American Saffron), which carries Moderate-severity interactions with blood thinners (anticoagulants) and warfarin. High doses of safflower oil can increase bleeding risk; one case report documented a patient on warfarin who developed urinary tract bleeding and an elevated INR after taking a safflower extract at 20 grams daily for 14 days.
This product's exact safflower dose isn't specified in the label, so you'll need to check the bottle.
Read the full breakdown — every affected drug type, severity by severity
Safflower also interacts Moderately with diabetes drugs. Some research shows safflower oil can raise fasting blood sugar in people with type 2 diabetes, so it may interfere with how your diabetes medication works.
Slippery elm carries a Moderate interaction with oral medications in general. Its mucilage may slow how your body absorbs swallowed drugs, potentially lowering the amount that reaches your bloodstream.
This can affect many prescription and over-the-counter medications.
Although this product contains only two active ingredients, these interactions span 2,049 individual medications. Before you start, run your exact medications through the interaction checker below.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against American Saffron & Slippery Elm Vanilla Flavor?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in American Saffron & Slippery Elm Vanilla Flavor interact with 2,068 drugs. Click any drug to see the details.
1 of the 1 ingredient in American Saffron & Slippery Elm Vanilla Flavor interact with drugs. Each result below shows which ingredient is responsible. American Saffron and Slippery Elm Glycerite Liquid Extract
"phentolamineOraVerse, Rogitine, Ryzumvi
How "phentolamine interacts with American Saffron & Slippery Elm Vanilla Flavor — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Glycerite Liquid ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Glycerite Liquid Extract + "phentolamine interaction6-mercaptopurinePurinethol
How 6-mercaptopurine interacts with American Saffron & Slippery Elm Vanilla Flavor — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Glycerite Liquid ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Glycerite Liquid Extract + 6-mercaptopurine interactionAbacavirZiagen
How Abacavir interacts with American Saffron & Slippery Elm Vanilla Flavor — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Glycerite Liquid ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Glycerite Liquid Extract + Abacavir interactionAbacavir Sulfate, Dolutegravir, LamivudineTriumeq
How Abacavir Sulfate, Dolutegravir, Lamivudine interacts with American Saffron & Slippery Elm Vanilla Flavor — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Glycerite Liquid ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Glycerite Liquid Extract + Abacavir Sulfate, Dolutegravir, Lamivudine interactionAbacavir, LamivudineEpzicom
How Abacavir, Lamivudine interacts with American Saffron & Slippery Elm Vanilla Flavor — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Glycerite Liquid ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Glycerite Liquid Extract + Abacavir, Lamivudine interactionAbciximabReoPro
How Abciximab interacts with American Saffron & Slippery Elm Vanilla Flavor — through 2 ingredients. Tap an ingredient for the detail:
American Saffron Glycerite Liquid ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
High doses of safflower oil might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full American Saffron Glycerite Liquid Extract + Abciximab interactionSlippery Elm Glycerite Liquid ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Glycerite Liquid Extract + Abciximab interactionAbemaciclibVerzenio
How Abemaciclib interacts with American Saffron & Slippery Elm Vanilla Flavor — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Glycerite Liquid ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Glycerite Liquid Extract + Abemaciclib interactionAbiraterone
How Abiraterone interacts with American Saffron & Slippery Elm Vanilla Flavor — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Glycerite Liquid ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Glycerite Liquid Extract + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with American Saffron & Slippery Elm Vanilla Flavor — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Glycerite Liquid ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Glycerite Liquid Extract + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with American Saffron & Slippery Elm Vanilla Flavor — through 2 ingredients. Tap an ingredient for the detail:
Slippery Elm Glycerite Liquid ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Glycerite Liquid Extract + Abrocitinib interactionAmerican Saffron Glycerite Liquid ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
High doses of safflower oil might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full American Saffron Glycerite Liquid Extract + Abrocitinib interactionAcalabrutinibCalquence
How Acalabrutinib interacts with American Saffron & Slippery Elm Vanilla Flavor — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Glycerite Liquid ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Glycerite Liquid Extract + Acalabrutinib interactionAcamprosateCampral
How Acamprosate interacts with American Saffron & Slippery Elm Vanilla Flavor — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Glycerite Liquid ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Glycerite Liquid Extract + Acamprosate interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with American Saffron & Slippery Elm Vanilla Flavor — through 2 ingredients. Tap an ingredient for the detail:
American Saffron Glycerite Liquid ExtractAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, safflower oil might alter the effects of antidiabetes drugs.
Read the full American Saffron Glycerite Liquid Extract + Acarbose interactionSlippery Elm Glycerite Liquid ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Glycerite Liquid Extract + Acarbose interactionAcebutololRhotral, Sectral
How Acebutolol interacts with American Saffron & Slippery Elm Vanilla Flavor — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Glycerite Liquid ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Glycerite Liquid Extract + Acebutolol interactionAcenocoumarolSintrom
How Acenocoumarol interacts with American Saffron & Slippery Elm Vanilla Flavor — through 2 ingredients. Tap an ingredient for the detail:
American Saffron Glycerite Liquid ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
High doses of safflower oil might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full American Saffron Glycerite Liquid Extract + Acenocoumarol interactionSlippery Elm Glycerite Liquid ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Glycerite Liquid Extract + Acenocoumarol interactionAcepromazineAtravet
How Acepromazine interacts with American Saffron & Slippery Elm Vanilla Flavor — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Glycerite Liquid ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Glycerite Liquid Extract + Acepromazine interactionAcetaminophenChildren's Tylenol, Children's Tylenol Meltaways, Tylenol, Tylenol Ex Strength
How Acetaminophen interacts with American Saffron & Slippery Elm Vanilla Flavor — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Glycerite Liquid ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Glycerite Liquid Extract + Acetaminophen interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with American Saffron & Slippery Elm Vanilla Flavor — through 2 ingredients. Tap an ingredient for the detail:
Slippery Elm Glycerite Liquid ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Glycerite Liquid Extract + Acetaminophen, Aspirin interactionAmerican Saffron Glycerite Liquid ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
High doses of safflower oil might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full American Saffron Glycerite Liquid Extract + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with American Saffron & Slippery Elm Vanilla Flavor — through 2 ingredients. Tap an ingredient for the detail:
American Saffron Glycerite Liquid ExtractAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
High doses of safflower oil might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full American Saffron Glycerite Liquid Extract + Acetaminophen, Aspirin, Caffeine interactionSlippery Elm Glycerite Liquid ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Glycerite Liquid Extract + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Brompheniramine, PhenylpropanolamineDimetapp Cold and Flu
How Acetaminophen, Brompheniramine, Phenylpropanolamine interacts with American Saffron & Slippery Elm Vanilla Flavor — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Glycerite Liquid ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Glycerite Liquid Extract + Acetaminophen, Brompheniramine, Phenylpropanolamine interactionAcetaminophen, ButalbitalAxocet, Bancap, Bucet, Butex Forte, Esgic CF, Orbivan CF +5 more
How Acetaminophen, Butalbital interacts with American Saffron & Slippery Elm Vanilla Flavor — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Glycerite Liquid ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Glycerite Liquid Extract + Acetaminophen, Butalbital interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with American Saffron & Slippery Elm Vanilla Flavor — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Glycerite Liquid ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Glycerite Liquid Extract + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with American Saffron & Slippery Elm Vanilla Flavor — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Glycerite Liquid ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Glycerite Liquid Extract + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Butalbital, CodeineBancap w/ Codeine
How Acetaminophen, Butalbital, Codeine interacts with American Saffron & Slippery Elm Vanilla Flavor — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Glycerite Liquid ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Glycerite Liquid Extract + Acetaminophen, Butalbital, Codeine interactionAcetaminophen, Butalbital, Codeine PhosphatePhrenilin #3
How Acetaminophen, Butalbital, Codeine Phosphate interacts with American Saffron & Slippery Elm Vanilla Flavor — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Glycerite Liquid ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Glycerite Liquid Extract + Acetaminophen, Butalbital, Codeine Phosphate interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with American Saffron & Slippery Elm Vanilla Flavor — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Glycerite Liquid ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Glycerite Liquid Extract + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with American Saffron & Slippery Elm Vanilla Flavor — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Glycerite Liquid ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Glycerite Liquid Extract + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with American Saffron & Slippery Elm Vanilla Flavor — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Glycerite Liquid ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Glycerite Liquid Extract + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with American Saffron & Slippery Elm Vanilla Flavor — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Glycerite Liquid ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Glycerite Liquid Extract + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with American Saffron & Slippery Elm Vanilla Flavor — through 1 ingredient. Tap an ingredient for the detail:
Slippery Elm Glycerite Liquid ExtractOral Drugs Moderate
Interaction Summary
Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Read the full Slippery Elm Glycerite Liquid Extract + Acetaminophen, Caffeine, Isometheptene interactionEach ingredient & the kinds of drugs it affects
For each ingredient in American Saffron & Slippery Elm Vanilla Flavor with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
American Saffron and Slippery Elm Glycerite Liquid Extract
Anticoagulant/Antiplatelet Drugs
High doses of safflower oil might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Small clinical studies show that taking safflower oil, approximately 55 grams daily for 2-3 weeks, decreases platelet aggregation. However, taking lower doses of safflower oil, such as 5 grams daily for 4 weeks, does not seem to affect platelet function. In one case report, a 74-year-old male stabilized on warfarin developed urinary tract bleeding and an elevated INR after taking a safflower extract 20 grams daily for 14 days.
Antidiabetes Drugs
Theoretically, safflower oil might alter the effects of antidiabetes drugs.
Some clinical research shows that taking safflower oil 10 grams daily for 3 weeks can increase fasting blood glucose in patients with type 2 diabetes. However, clinical research in patients with metabolic syndrome with or without impaired glucose tolerance shows that taking safflower oil 8 grams daily for 12 weeks reduces fasting glucose levels by around 8 mg/dL. Some clinical research also shows that taking safflower oil 8 grams daily for 16 weeks does not affect fasting glucose levels in patients with type 2 diabetes.
Warfarin
Theoretically, safflower oil might increase the risk of bleeding when taken with warfarin.
In one case report, a 74-year-old male stabilized on warfarin developed urinary tract bleeding and an elevated INR after taking a safflower extract 20 grams daily for 14 days.
Brand information
Manufacturer and brand details for American Saffron & Slippery Elm Vanilla Flavor, from the product label.
TerraVita
See all TerraVita products- Name
- TerraVita Fine Herbs
- Phone Number
- 844-449-0444
- Web Address
- www.ZooScape.com
American Saffron & Slippery Elm Vanilla Flavor by TerraVita: Common Questions
Does American Saffron & Slippery Elm Vanilla Flavor by TerraVita interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Will this slow down my other medications?
Is it safe to take with blood thinners?
Can I take this if I have diabetes?
Is safflower safe for weight loss?
Can I use this while pregnant or breastfeeding?
Can I have an allergic reaction to this?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if American Saffron & Slippery Elm Vanilla Flavor is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind American Saffron & Slippery Elm Vanilla Flavor’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Safflower
Interacts with 208 drugsSafflower is a thistle-like plant used mainly for its seed oil (a common cooking oil) and its colorful flowers. Safflower oil is a reasonable source of unsaturated fats, but strong proof tha...
Read the full Safflower monograph → Herb & supplement monographSlippery Elm
Interacts with 2,022 drugsSlippery elm is a traditional herbal remedy made from the inner bark of a North American elm tree, used mainly to soothe sore throats and irritated digestive tracts. Its mucilage can coat an...
Read the full Slippery Elm monograph →Sources & How We Checked
American Saffron & Slippery Elm Vanilla Flavor's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 17 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Safflower 14 references
- The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
- Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Borkman M, Chisholm DJ, Furler SM, et al. Effects of fish oil supplementation on glucose and lipid metabolism in NIDDM. Diabetes 1989;38:1314-9.. PubMed
- Amato, P. and Quercia, R. A. A historical perspective and review of the safety of lipid emulsion in pregnancy. Nutr Clin Pract. 1991;6(5):189-192. PubMed
- Demke, D. M., Peters, G. R., Linet, O. I., Metzler, C. M., and Klott, K. A. Effects of a fish oil concentrate in patients with hypercholesterolemia. Atherosclerosis 1988;70(1-2):73-80. PubMed
- Kaji, K., Yoshida, S., Nagata, N., Yamashita, T., Mizukoshi, E., Honda, M., Kojima, Y., and Kaneko, S. An open-label study of administration of EH0202, a health-food additive, to patients with chronic hepatitis C. J Gastroenterol. 2004;39(9):873-878. PubMed
- Kwon, J. S., Snook, J. T., Wardlaw, G. M., and Hwang, D. H. Effects of diets high in saturated fatty acids, canola oil, or safflower oil on platelet function, thromboxane B2 formation, and fatty acid composition of platelet phospholipids. Am.J.Clin.Nutr. PubMed
- Lloyd-Still, J. D., Simon, S. H., Wessel, H. U., and Gibson, L. E. Negative effects of oral fatty acid supplementation on sweat chloride in cystic fibrosis. Pediatrics 1979;64(1):50-52. DOI
- Challen, A. D., Branch, W. J., and Cummings, J. H. The effect of aspirin and linoleic acid on platelet aggregation, platelet fatty acid composition and haemostasis in man. Hum Nutr Clin Nutr 1983;37(3):197-208.
- Asp ML, Collene AL, Norris LE, Cole RM, Stout MB, Tang SY, Hsu JC, Belury MA. Time-dependent effects of safflower oil to improve glycemia, inflammation and blood lipids in obese, post-menopausal women with type 2 diabetes: a randomized, double-masked, cro
- Liu Y, Liu S, Shi Y, et al. Effects of safflower injection on the pharmacodynamics and pharmacokinetics of warfarin in rats. Xenobiotica. 2017 Oct 25:1-6. [Epub ahead of print] PubMed
- de Ataide EC, Reges Perales S, de Oliveira Peres MA, et al. Acute liver failure induced by Carthamus tinctorius oil: Case reports and literature review. Transplant Proc. 2018;50(2):476-477. PubMed
- Ruyvaran M, Zamani A, Mohamadian A, et al. Safflower (Carthamus tinctorius L.) oil could improve abdominal obesity, blood pressure, and insulin resistance in patients with metabolic syndrome: a randomized, double-blind, placebo-controlled clinical trial. PubMed
Slippery Elm 3 references
- The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- Czarnecki D, Nixon R, Bekhor P, and et al. Delayed prolonged contact urticaria from the elm tree. Contact Dermatitis 1993;28:196-197. PubMed
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