Interactions on record — worth a quick check against your medications. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

Antarctic Krill Oil 2000 mg Ingredients & Drug Interactions

by Approved Science

Antarctic Krill Oil 2000 mg label
See full label image
Softgel Capsule Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Antarctic Krill Oil 2000 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Antarctic Krill Oil 2000 mg is a dietary supplement by Approved Science with 2 active ingredients. Its ingredients are commonly taken for antioxidant support, skin health and aging, eye health.Based on those ingredients, 673 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Astaxanthin. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Antarctic Krill Oil 2000 mg by Approved Science

Ask about any prescription or over-the-counter medication and we check it for interactions with Antarctic Krill Oil 2000 mg by Approved Science — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Antarctic Krill Oil 2000 mg by Approved Science

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 5 of its 5 active ingredients.
  • “Phospholipid Omega-3 Complex” is a proprietary blend — the label gives one combined amount (680 mg) without saying how much of each component you get.
  • “Krill-Sci Krill Oil” is listed as a grouped ingredient — the label gives one combined amount (2,000 mg) without saying how much of each component you get.

This product has 5 active ingredients. The main components are three omega-3 fatty acids — eicosapentaenoic acid, docosahexaenoic acid, and other fatty acids — which are the omega-3s people take krill oil for.

It also contains astaxanthin, a red pigment from krill with antioxidant properties, and phospholipids, which are fat-like compounds that help your body absorb the other ingredients. The capsule itself is made from gelatin and glycerin.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Astaxanthin product and its label doesn't state a use — see Astaxanthin's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence we hold for astaxanthin doesn't support a firm rating for any condition. We have insufficient reliable evidence for age-related cognitive decline, age-related macular degeneration (AMD), aging skin, Alzheimer disease, athletic performance, and carpal tunnel syndrome.

We don't have effectiveness data on file for the omega-3 fatty acids in this product.

The evidence, ingredient by ingredient Astaxanthin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Astaxanthin is generally well tolerated in studies, though long-term safety data are limited. The most common side effects reported orally are abdominal pain, diarrhea, and red-colored stools.

At standard doses (6 mg daily), a small number of trial participants experienced increased bowel movements and red fecal color; at higher doses (40 mg daily), severe stomach pain has been reported in a small number of people. There isn't enough safety data to know whether astaxanthin is safe in pregnancy, so the data advises against it during pregnancy.

The same applies to breastfeeding — talk with your pharmacist or doctor if you're pregnant or nursing and want to use this product.

Side effects, ingredient by ingredient Astaxanthin

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Astaxanthin.
  • The most serious interaction on file is rated Moderate.
  • For scale: 674 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this product, check whether you're on any medications broken down by the liver enzymes CYP3A4 or CYP2B6 — astaxanthin may theoretically lower their levels. These include some blood pressure medications, certain immunosuppressants, and some cholesterol drugs.

Run your exact medications through the checker on this page.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This krill oil supplement is primarily a source of omega-3 fatty acids, with added astaxanthin. If you take medications processed through your liver — especially certain blood pressure drugs, immunosuppressants, or statins — check with your pharmacist before starting.

Pregnant and breastfeeding individuals should talk to their doctor first because safety data are limited.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 5 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 22, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Antarctic Krill Oil 2000 mg, straight from the product label.

Brand Approved Science
Barcode (UPC) X002WNPS97
Net contents 60 Softgel(s)
Market status On market
Date entered into DSLD Nov 22, 2024
DSLD ID 319716
Product type Other Combinations
Supplement form Softgel Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Antarctic Krill Oil 2000 mg by Approved Science, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
Servings per container
30
UPC/BARCODE
X002WNPS97
IngredientAmount% DV
Eicosapentaenoic Acid260 mg--
Docosahexaenoic Acid160 mg--
Other Fatty Acids200 mg--
Astaxanthin650 mcg--
Phospholipids60 mg--
Phospholipid Omega-3 Complex680 mg--
Krill-Sci Krill Oil2000 mg--

Other ingredients: Gelatin, Glycerin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, take two softgels daily (one in the morning and one in the afternoon), before meals with an 8 oz. glass of water.

Precautions

Caution: Do not exceed recommended dose. Do not use if safety seal is damaged or missing.

Pregnant women or nursing mothers, children under 18, and individuals with a known medical condition, should consult with a physician before taking this or any other dietary supplement.

Pregnant women or nursing mothers, children under 18, and individuals with a known medical condition, should consult with a physician before taking this or any other dietary supplement. Keep out of reach of children.

Contains shellfish

Storage

Store at room temperature.

Formulation

Manufactured in the USA according to current Good Manufacturing Practice (cGMP) and conforms to the tested ingredients grade, strength and purity of industry Quality Standards.

Made with GMO free ingredients

Premium grade High potency Safe Fast Natural formula Optimal strength GMP Certified

Seals/Symbols

Made in USA Friend Of The Sea Certified Sustainable Seafood www.MSC.org No animal testing GMP Good Manufacturing Practice Quality Product

Formula

High absorption krill oil Antarctic Krill Oil with Krill-Sci 2000mg Non-GMO Oil

FDA Statement of Identity

Dietary Supplement

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Antarctic Krill Oil 2000 mg by Approved Science label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Antarctic Krill Oil 2000 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Antarctic Krill Oil 2000 mg by Approved Science

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Astaxanthin

Interacts with
673 drugs
650 mcg per serving

Astaxanthin is a reddish carotenoid pigment with strong antioxidant activity in the lab, and it is widely promoted for skin, eye, heart, and exercise...

Astaxanthin monograph & interactions

Krill-Sci Krill Oil

2000 mg per serving
  • › Phospholipid Omega-3 Complex

Other (inactive) ingredients: Gelatin, Glycerin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Antarctic Krill Oil 2000 mg by Approved Science Drug Interactions

Want to check YOUR meds against Antarctic Krill Oil 2000 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
673Drugs
673 Moderate

Ingredients driving the most interactions

Astaxanthin 673

Individual Drug Interactions

The ingredients in Antarctic Krill Oil 2000 mg interact with 673 drugs. Click any drug to see the details.

1 of the 2 ingredients in Antarctic Krill Oil 2000 mg interact with drugs. Each result below shows which ingredient is responsible. Astaxanthin

Each ingredient & the kinds of drugs it affects

For each ingredient in Antarctic Krill Oil 2000 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Astaxanthin2 drug types · 673 drugs

Cytochrome P450 2B6 (Cyp2B6) Substrates

Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP2B6.
In vitro research shows that astaxanthin induces cytochrome CYP2B6 enzyme activity in human hepatocytes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP3A4.
In vitro research shows that astaxanthin induces CYP3A4 enzyme activity in human hepatocytes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Astaxanthin full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Antarctic Krill Oil 2000 mg, from the product label.

Approved Science

See all Approved Science products
Name
Approved Science
City
New York
State
NY
ZipCode
10003
Phone Number
888-307-4790
Web Address
www.approvedscience.com
Pharmacist Counseling Corner

Antarctic Krill Oil 2000 mg by Approved Science: Common Questions

Does Antarctic Krill Oil 2000 mg by Approved Science interact with any medications?
Yes. Based on its ingredients, Antarctic Krill Oil 2000 mg has a known interaction with 673 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Antarctic Krill Oil 2000 mg contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this while I'm pregnant?
There isn't enough safety data to know either way. The facts advise against it during pregnancy. Talk with your doctor or pharmacist for personalized advice before starting.
Is it safe to breastfeed while taking this supplement?
There isn't enough safety data, so it's best to avoid it while breastfeeding. Check with your pharmacist or doctor about what's safe for you and your baby.
What are the most common side effects?
Abdominal pain, diarrhea, and red-colored stools are the most commonly reported side effects. Most people tolerate it well, but long-term safety data are limited.
Does astaxanthin in this product actually work for anything?
We don't have enough reliable evidence to say whether astaxanthin helps with age-related cognitive decline, macular degeneration, skin aging, or any of the other conditions studied. The evidence on file is insufficient to rate it.
What are the omega-3s in krill oil for?
The three main omega-3 fatty acids in krill oil are eicosapentaenoic acid and docosahexaenoic acid, plus other fatty acids. We don't have effectiveness data on file for them in this product, though omega-3s are widely studied for heart and brain health.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Antarctic Krill Oil 2000 mg is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Antarctic Krill Oil 2000 mg label
Go deeper

The Full Monographs Behind Antarctic Krill Oil 2000 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Astaxanthin

Interacts with 673 drugs

Astaxanthin is a reddish carotenoid pigment with strong antioxidant activity in the lab, and it is widely promoted for skin, eye, heart, and exercise benefits. Early human studies are promis...

Read the full Astaxanthin monograph →
Sources

Sources & How We Checked

Antarctic Krill Oil 2000 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 3 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Astaxanthin 3 references
  1. Kupcinskas L, Lafolie P, Lignell A, et al. Efficacy of the natural antioxidant astaxanthin in the treatment of functional dyspepsia in patients with or without Helicobacter pylori infection: A prospective, randomized, double blind, and placebo-controlled
  2. Kistler, A., Liechti, H., Pichard, L., Wolz, E., Oesterhelt, G., Hayes, A., and Maurel, P. Metabolism and CYP-inducer properties of astaxanthin in man and primary human hepatocytes. Arch.Toxicol. 2002;75(11-12):665-675. PubMed
  3. Choi HD, Youn YK, Shin WG. Positive effects of astaxanthin on lipid profiles and oxidative stress in overweight subjects. Plant Foods Hum Nutr. 2011;66:363-369. PubMed

See these in context on the Astaxanthin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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