Interactions on record — worth a quick check against your medications. Based on 2 of 3 ingredients. Check your meds →
Dietary supplement

Anti-Aging Collagen HA Total Revitalizing Essence Ingredients & Drug Interactions

by CATALO

Anti-Aging Collagen HA Total Revitalizing Essence label
See full label image
Capsule Category: Amino Acid/protein
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 30, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Anti-Aging Collagen HA Total Revitalizing Essence against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Anti-Aging Collagen HA Total Revitalizing Essence is a dietary supplement by CATALO with 3 active ingredients. Its ingredients are commonly taken for skin hydration and aging, joint comfort and osteoarthritis, dry eyes.Based on those ingredients, 2 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Chondroitin Sulfate, Depolymerized. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Anti-Aging Collagen HA Total Revitalizing Essence by CATALO

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HelloPharmacist Scorecard of Anti-Aging Collagen HA Total Revitalizing Essence by CATALO

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 12, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 3 of its 3 active ingredients.
  • “BioCell Collagen” is listed as a grouped ingredient — the label gives one combined amount (500 mg) without saying how much of each component you get.

This capsule contains three active ingredients. Hyaluronic acid is a naturally occurring substance that holds water in the skin and joints.

Collagen type II (hydrolyzed) is a broken-down form of a structural protein found in cartilage and connective tissue. Chondroitin sulfate is another component of cartilage that may help maintain joint structure.

The product also contains rice powder, gelatin, and magnesium stearate as inactive ingredients (common binders and fillers).

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use.

Why this rating?
  • The label markets this product for: skin health, elasticity, moisture and anti-aging.
  • We looked for evidence on: Aging skin, Wound healing, Skin elasticity, Skin hydration, Skin texture.
  • The closest evidence on file: Chondroitin Sulfate is rated "Insufficient Reliable Evidence To Rate" for Aging skin (Natural Medicines).
  • Also on file: Hyaluronic Acid is rated "Insufficient Reliable Evidence To Rate" for Aging skin, Wound healing.

The evidence for this product's anti-aging claims is limited. Hyaluronic acid has possibly effective evidence for dry eyes and venous leg ulcers, but for aging skin itself, the evidence isn't strong enough to rate.

Chondroitin sulfate is possibly effective for osteoarthritis and cataracts, but again, evidence for its effect on aging skin is insufficient. So while these are well-studied ingredients in other contexts, we don't have solid data showing they reverse or prevent skin aging when taken by mouth.

The evidence, ingredient by ingredient Hyaluronic Acid Chondroitin Sulfate

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Hyaluronic acid taken by mouth appears well tolerated overall, but long-term safety data for oral supplements isn't complete—caution is warranted if you plan to use it long-term. Chondroitin sulfate is also generally well tolerated for short-term use, though quality varies between products.

The most common side effects are mild digestive upset: abdominal pain, bloating, constipation, diarrhea, heartburn, and nausea. Rare cases of liver damage have been reported.

Some people have experienced skin symptoms like swelling, hair loss, or rash, and a few cases of asthma flare-ups have been reported with glucosamine-chondroitin combinations. Chondroitin is not recommended during pregnancy or while breastfeeding due to insufficient safety data.

Hyaluronic acid's pregnancy and breastfeeding safety is also not well documented—talk with your doctor or pharmacist if you're pregnant or nursing.

Side effects, ingredient by ingredient Hyaluronic Acid Chondroitin Sulfate

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 2 matched ingredients can interact with medications — Chondroitin Sulfate.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 2 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take warfarin (Coumadin) or any other blood thinner, flag this product before you start. Chondroitin may increase blood-thinning effects.

No other medication interactions are documented for the ingredients we could check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

This product may appeal to people looking for joint and skin support, though the anti-aging claim isn't backed by strong evidence. If you take warfarin or any blood thinner, check with us first.

Pregnant or nursing? You'll want to discuss this with your doctor or pharmacist before starting.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 22, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Anti-Aging Collagen HA Total Revitalizing Essence, straight from the product label.

Brand CATALO
Net contents 7 Capsule(s); 23.8 Gram(s)
Market status On market
Date entered into DSLD Feb 22, 2024
DSLD ID 302995
Product type Amino Acid/protein
Supplement form Capsule
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Anti-Aging Collagen HA Total Revitalizing Essence by CATALO, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
7
IngredientAmount% DV
Hyaluronic Acid50 mg--
BioCell Collagen500 mg--
Collagen Type II, Hydrolyzed300 mg--
Chondroitin Sulfate, Depolymerized100 mg--

Other ingredients: Rice, Powder, Gelatin, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

Catalo Health & beauty from within

Formulation

Advanced skin care Nourishes your skin from the inside out to provide powerful anti-aging properties and promote crystal clear skin

Nutritional support Premium skin care

Especially formulated for advanced skin care Catalo Advanced Skin Pure contains premium ingredients that nourish your skin from the inside out.

Main functions: Boost skin moisture and elasticity to help promote both visible volume and texture of skin Smoothen skin to make it look more plumped and refined, promote healthy hair growth, strengthen hair and nails Reduce dark spots, wrinkles, fine lines and signs of aging Lighten and brighten skin tones to promote healthy glowing and crystal clear skin Provide strong anti-oxidative power to fight against harmful free radicals and maintain youthful look

Suitable for: People who want to reduce signs of aging, beautify skin, hair and nails, eliminate wrinkles and dark spots, and maintain healthy crystal clear skin

General Statements

7 packets

Net weight: 23.8g (3.4g x 7 packets)

FDA Statement of Identity

Dietary Supplement

Formula

It also provides U.S. Patented BioCell Collagen and Multi-Antioxidants Complex to increase collagen content in the skin's dermis and reduce free-radical attacks that cause skin aging, thus, making your skin look more plumped and refined.

Suggested/Recommended/Usage/Directions

Serving directions: For adult take 1 packet daily after meal.

Storage

Keep in a dry and cool place. Avoid direct sunlight.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Anti-Aging Collagen HA Total Revitalizing Essence by CATALO label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Anti-Aging Collagen HA Total Revitalizing Essence label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Anti-Aging Collagen HA Total Revitalizing Essence by CATALO

These are the 3 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container7 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

BioCell Collagen

500 mg per serving Form: Collagen Extract

Other (inactive) ingredients: Rice, Powder, Gelatin, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Anti-Aging Collagen HA Total Revitalizing Essence by CATALO Drug Interactions

Want to check YOUR meds against Anti-Aging Collagen HA Total Revitalizing Essence?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
2Drugs
2 Moderate

Ingredients driving the most interactions

Chondroitin Sulfate, Depolymerized 2

Individual Drug Interactions

The ingredients in Anti-Aging Collagen HA Total Revitalizing Essence interact with 2 drugs. Click any drug to see the details.

1 of the 3 ingredients in Anti-Aging Collagen HA Total Revitalizing Essence interact with drugs. Each result below shows which ingredient is responsible. Chondroitin Sulfate, Depolymerized

Each ingredient & the kinds of drugs it affects

For each ingredient in Anti-Aging Collagen HA Total Revitalizing Essence with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Chondroitin Sulfate, Depolymerized1 drug type · 2 drugs

Warfarin (Coumadin)

Taking chondroitin in combination with glucosamine might increase the anticoagulant effects of warfarin. However, the effect of chondroitin alone is unclear.
There have been multiple reports of increased international normalized ratio (INR) in patients taking warfarin with glucosamine, with or without chondroitin. The lack of reports with chondroitin alone seem to suggest that the interactions occurring in these reports may have been due to glucosamine. In two individual case reports, glucosamine/chondroitin combinations were associated with a significant increase in INR in patients previously stabilized on warfarin. Additionally, 20 voluntary case reports to the US Food & Drug Administration (FDA) have linked glucosamine plus chondroitin with increased INR, bruising, and bleeding in patients who were also taking warfarin. There have also been 20 additional case reports to the World Health Organization (WHO) that link glucosamine alone, without chondroitin, to increased INR in patients taking warfarin.

Likelihood Unlikely Evidence D
Chondroitin Sulfate, Depolymerized full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Anti-Aging Collagen HA Total Revitalizing Essence, from the product label.

CATALO

See all CATALO products
Name
CATALO
Pharmacist Counseling Corner

Anti-Aging Collagen HA Total Revitalizing Essence by CATALO: Common Questions

Does Anti-Aging Collagen HA Total Revitalizing Essence by CATALO interact with any medications?
Yes. Based on its ingredients, Anti-Aging Collagen HA Total Revitalizing Essence has a known interaction with 2 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Anti-Aging Collagen HA Total Revitalizing Essence contains 3 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this help my aging skin?
That's the claim, but the evidence isn't there yet. Hyaluronic acid and chondroitin have possibly effective evidence for other uses—like dry eyes and osteoarthritis—but when it comes to aging skin specifically, the data we have isn't strong enough to rate. It's worth discussing with your doctor if you're looking for proven anti-aging options.
What are the most common side effects?
If you experience any digestive upset—bloating, constipation, diarrhea, heartburn, or nausea—that's the most likely culprit. These are mild and not severe, but they do happen. Skin symptoms like swelling or rash are less common but have been reported.
Can I take this while pregnant?
The safety data for both hyaluronic acid and chondroitin during pregnancy isn't solid enough to recommend it. There's not enough information either way. Talk with your doctor or pharmacist before starting if you're pregnant or planning to become pregnant.
Can I take this while breastfeeding?
Chondroitin specifically is advised against while breastfeeding due to lack of safety data. Hyaluronic acid's breastfeeding safety also isn't well documented. Check with your pharmacist or doctor to be sure it's okay for your situation.
What's hydrolyzed collagen?
It's collagen—a structural protein in your joints, skin, and connective tissue—that's been broken down into smaller pieces so your body can absorb it more easily when you swallow it.
Is this product gluten-free or vegan?
The ingredients list shows gelatin (an animal-derived ingredient), so this product is not vegan. We don't have information on whether it's gluten-free—check the label or contact the manufacturer directly.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Anti-Aging Collagen HA Total Revitalizing Essence label
Go deeper

The Full Monographs Behind Anti-Aging Collagen HA Total Revitalizing Essence’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Hyaluronic Acid

Hyaluronic acid is a natural substance in the body that helps hold water in the skin, joints, and eyes. Oral and topical products are popular for skin moisture and joint comfort, and the evi...

Read the full Hyaluronic Acid monograph → Herb & supplement monograph

Chondroitin Sulfate

Interacts with 2 drugs

Chondroitin sulfate is a naturally occurring building block of cartilage that is widely taken, often with glucosamine, for osteoarthritis joint pain. The evidence is mixed—some people report...

Read the full Chondroitin Sulfate monograph →
Sources

Sources & How We Checked

Anti-Aging Collagen HA Total Revitalizing Essence's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 26 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Hyaluronic Acid 4 references
  1. Park Y, Song JS, Choi CY, Yoon KC, Lee HK, Kim HS. A randomized multicenter study comparing 0.1%, 0.15%, and 0.3% sodium hyaluronate with 0.05% cyclosporine in the treatment of dry eye. J Ocul Pharmacol Ther. 2017;33(2):66-72. PubMed
  2. U.S. Food and Drug Administration. Do Not Use Needle-Free Devices for Injection of Dermal Fillers - FDA Safety Communication. October 8, 2021. Available at: https://www.fda.gov/medical-devices/safety-communications/do-not-use-needle-free-devices-injection
  3. Disphanurat W, Srisantithum B. Efficacy and safety of 0.15% isobutylamido thiazolyl resorcinol combined with hyaluronic acid vs 0.15% isobutylamido thiazolyl resorcinol or hyaluronic acid alone in melasma treatment: A randomized evaluator-blind trial. J C PubMed
  4. Humbert P, Mikosinki J, Benchikhi H, Allaert FA. Efficacy and safety of a gauze pad containing hyaluronic acid in treatment of leg ulcers of venous or mixed origin: a double-blind, randomised, controlled trial. Int Wound J 2013;10(2):159-66. PubMed

See these in context on the Hyaluronic Acid monograph →

Chondroitin Sulfate 22 references
  1. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Vitamin A, Vitamin K, Arsenic, Boron, Chromium, Copper, Iodine, Iron, Manganese, Molybdenum, Nickel, Silicon, Vanadium, and Zinc. Washington, DC: National Academy Press, 2002.
  2. Tallia AF, Cardone DA. Asthma exacerbation associated with glucosamine-chondroitin supplement. J Am Board Fam Pract 2002;15:481-4..
  3. Danao-Camara T. Potential side effects of treatment with glucosamine and chondroitin. Arthritis Rheum 2000;43:2853. PubMed
  4. Rozenfeld V, Crain JL, Callahan AK. Possible augmentation of warfarin effect by glucosamine-chondroitin. Am J Health Syst Pharm 2004;61:306-307. PubMed
  5. Clegg DO, Reda DJ, Harris CL, et al. Glucosamine, chondroitin sulfate, and the two in combination for painful knee osteoarthritis. N Engl J Med 2006;354:795-808. DOI
  6. Knudsen J, Sokol GH. Potential glucosamine-warfarin interaction resulting in increased international normalized ratio: Case report and review of the literature and MedWatch database. Pharmacotherapy 2008;28:540-8. PubMed
  7. Yue QY, Strandell J, Myrberg O. Concomitant use of glucosamine potentiates the effect of warfarin. Jan 2006. Drug Safety 29(10):911-1010. DOI
  8. Nordling, J. and van, Ophoven A. Intravesical glycosaminoglycan replenishment with chondroitin sulphate in chronic forms of cystitis. A multi-national, multi-centre, prospective observational clinical trial. Arzneimittelforschung. 2008;58(7):328-335. PubMed
  9. Nickel, J. C., Egerdie, B., Downey, J., Singh, R., Skehan, A., Carr, L., and Irvine-Bird, K. A real-life multicentre clinical practice study to evaluate the efficacy and safety of intravesical chondroitin sulphate for the treatment of interstitial cystit
  10. Oliviero, U., Sorrentino, G. P., De Paola, P., Tranfaglia, E., D'Alessandro, A., Carifi, S., Porfido, F. A., Cerio, R., Grasso, A. M., Policicchio, D., and . Effects of the treatment with matrix on elderly people with chronic articular degeneration. Drug
  11. Crowley, D. C., Lau, F. C., Sharma, P., Evans, M., Guthrie, N., Bagchi, M., Bagchi, D., Dey, D. K., and Raychaudhuri, S. P. Safety and efficacy of undenatured type II collagen in the treatment of osteoarthritis of the knee: a clinical trial. Int.J.Med.Sc PubMed
  12. Nickel, J. C., Egerdie, R. B., Steinhoff, G., Palmer, B., and Hanno, P. A multicenter, randomized, double-blind, parallel group pilot evaluation of the efficacy and safety of intravesical sodium chondroitin sulfate versus vehicle control in patients with
  13. Sawitzke, A. D., Shi, H., Finco, M. F., Dunlop, D. D., Harris, C. L., Singer, N. G., Bradley, J. D., Silver, D., Jackson, C. G., Lane, N. E., Oddis, C. V., Wolfe, F., Lisse, J., Furst, D. E., Bingham, C. O., Reda, D. J., Moskowitz, R. W., Williams, H. J.
  14. Wildi, L. M., Raynauld, J. P., Martel-Pelletier, J., Beaulieu, A., Bessette, L., Morin, F., Abram, F., Dorais, M., and Pelletier, J. P. Chondroitin sulphate reduces both cartilage volume loss and bone marrow lesions in knee osteoarthritis patients starti
  15. Pavelka and et al. Double-blind, dose effect study of oral cs 4 & 6 1200mg, 800mg, 200mg against placebo in the treatment of femorotibial osteoarthritis. Wular Rheumatol Liter 1998;27(suppl 2):63.
  16. Cerda C, Bruguera M, Parés A. Hepatotoxicity associated with glucosamine and chondroitin sulfate in patients with chronic liver disease. World J Gastroenterol 2013;19(32):5381-4. PubMed
  17. von Felden J, Montani M, Kessebohm K, Stickel F. Drug-induced acute liver injury mimicking autoimmune hepatitis after intake of dietary supplements containing glucosamine and chondroitin sulfate. Int J Clin Pharmacol Ther 2013;51(3):219-23. PubMed
  18. Provenza JR, Shinjo SK, Silva JM, Peron CR, Rocha FA. Combined glucosamine and chondroitin sulfate, once or three times daily, provides clinically relevant analgesia in knee osteoarthritis. Clin Rheumatol 2015;34:1455-62. PubMed
  19. Ossendza RA, Grandval P, Chinoune F, Rocher F, Chapel F, Bernardini D. [Acute cholestatic hepatitis due to glucosamine forte]. Gastroenterol Clin Biol. 2007 Apr;31(4):449-50.
  20. Greenlee H, Crew KD, Shao T, Kranwinkel G, Kalinsky K, Maurer M, Brafman L, Insel B, Tsai WY, Hershman DL. Phase II study of glucosamine with chondroitin on aromatase inhibitor-associated joint symptoms in women with breast cancer. Support Care Cancer 201 PubMed
  21. Chu EC, Huang KHK, Cheung G, Ng G, Lin A. Delayed Skin Allergy to Glucosamine Chondroitin Supplement. Cureus 2023;15(3):e36310. PubMed
  22. Lila AM, Alekseeva LI, Baranov AA, et al. Chondroitin sulfate and glucosamine combination in patients with knee and hip osteoarthritis: A long-term observational study in Russia. World J Orthop 2023;14(6):443-457. PubMed

See these in context on the Chondroitin Sulfate monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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