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Dietary supplement

Apoptosis Easy Digest Formula Ingredients & Drug Interactions

by TumoRx

Capsule Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Apoptosis Easy Digest Formula is a dietary supplement by TumoRx with 2 active ingredients. Its ingredients are commonly taken for sore throat and cough, heartburn and acid reflux, digestive upset and ibs.Based on those ingredients, 2,022 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Slippery Elm. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Apoptosis Easy Digest Formula by TumoRx

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 2 active ingredients.
  • “Proprietary Blend” is a proprietary blend — the label gives one combined amount (350 mg) without saying how much of each component you get.

This capsule contains two active ingredients: slippery elm and bloodroot, plus hypromellose (the capsule material itself). Slippery elm is the inner bark of the slippery elm tree, traditionally used to soothe the digestive tract.

Bloodroot is a plant extract that's been studied for oral health.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded its ingredients' overall clinical evidence instead.

Moderate

Some clinical evidence supports its ingredients for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredients' overall clinical evidence instead.
  • On file: Dental plaque — rated "Possibly Effective" (Bloodroot) (Natural Medicines).
  • On file: Gingivitis — rated "Possibly Effective" (Bloodroot) (Natural Medicines).

The evidence for what this formula actually does is limited. Slippery elm hasn't been studied enough to know whether it works for cancer, constipation, cough, diarrhea, or inflammatory bowel disease — the data just isn't there yet.

Bloodroot shows some promise for dental plaque and gingivitis, though even that's called 'possibly effective' rather than proven. For periodontitis, the evidence is also insufficient.

So we really don't have solid data on whether this combination works for its intended purpose.

The evidence, ingredient by ingredient Slippery Elm Bloodroot

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Slippery elm is generally well tolerated for short-term use, but high-quality safety data are limited. Some sources caution against it during pregnancy, and there's too little information on safety while breastfeeding — talk with your doctor or pharmacist about either situation.

Bloodroot is a different story: it's potentially toxic and corrosive, and we don't recommend it for self-treatment. Topical contact with fresh bloodroot can cause irritation or scarring; long-term oral use has been linked to mouth sores, leukoplakia, taste problems, and tooth staining.

High doses may cause nausea, vomiting, low blood pressure (hypotension), or even shock. Bloodroot is likely unsafe in pregnancy and possibly unsafe while breastfeeding.

Side effects, ingredient by ingredient Slippery Elm Bloodroot

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 2 matched ingredients can interact with medications — Slippery Elm.
  • The most serious interaction on file is rated Moderate.
  • For scale: 2,023 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Slippery elm can slow or reduce the absorption of oral medications — anything you take by mouth. This is a moderate-severity interaction that may make your drugs less effective.

Check all oral medications, including over-the-counter ones, before you start this supplement.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

This product pairs an herb with limited safety data (slippery elm) and one with significant safety concerns (bloodroot). If you take any oral medications, you need to check them against this product's interactions first.

Given bloodroot's toxicity profile and the weak evidence for either ingredient's effectiveness, talk with your pharmacist or doctor about whether this is the right choice for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Nov 25, 2013.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Apoptosis Easy Digest Formula, straight from the product label.

Brand TumoRx
Net contents 90 Capsule(s)
Market status On market
Date entered into DSLD Nov 25, 2013
DSLD ID 27494
Product type Botanical
Supplement form Capsule
Dietary claims / uses Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Apoptosis Easy Digest Formula by TumoRx, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
90
IngredientAmount% DV
Proprietary Blend350 mg--
Slippery Elm0 Not Present--
Bloodroot0 Not Present--

Other ingredients: Hypromellose Capsule

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Seals/Symbols

100% GUARANTEED FULL STRENGTH

Suggested/Recommended/Usage/Directions

Usage: As a dietary supplement consume 1 capsule per day or as directed by a health care professional.

General Statements

350mg

See for yourself

Apoptosis Easy Digest Formula by TumoRx label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Apoptosis Easy Digest Formula by TumoRx

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container90 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Blend

350 mg per serving

Other (inactive) ingredients: Hypromellose Capsule. These complete the product’s ingredient list but are not active constituents.

Interaction report

Apoptosis Easy Digest Formula by TumoRx Drug Interactions

Want to check YOUR meds against Apoptosis Easy Digest Formula?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
2,022Drugs
2,022 Moderate

Ingredients driving the most interactions

Slippery Elm 2,022

Each ingredient & the kinds of drugs it affects

For each ingredient in Apoptosis Easy Digest Formula with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Slippery Elm1 drug type · 2,022 drugs

Oral Drugs

Theoretically, slippery elm may slow the absorption and reduce serum levels of oral drugs.
Slippery elm inner bark contains mucilage, which may interfere with the absorption of orally administered drugs.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Apoptosis Easy Digest Formula, from the product label.

TumoRx

Name
BioAnue Laboratories Inc.
Street Address
P.O. Box 1056, 123 Wood Tech Dr.
City
Rochelle
State
GA
ZipCode
31079
Pharmacist Counseling Corner

Apoptosis Easy Digest Formula by TumoRx: Common Questions

Does Apoptosis Easy Digest Formula by TumoRx interact with any medications?
Yes. Based on its ingredients, Apoptosis Easy Digest Formula has a known interaction with 2,022 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Apoptosis Easy Digest Formula contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is it safe to take this while I'm pregnant or breastfeeding?
No. Bloodroot is likely unsafe in pregnancy and possibly unsafe while breastfeeding — it may be toxic, and safety data are limited. Slippery elm also has cautions in pregnancy and too little safety information for breastfeeding. Talk with your doctor or pharmacist before considering this product in either situation.
What is slippery elm supposed to do?
Slippery elm is traditionally used to soothe the digestive tract. However, we don't have enough reliable evidence to say it actually works for cancer, constipation, cough, diarrhea, or inflammatory bowel disease.
What about the bloodroot — what's it for?
Bloodroot has been studied for dental health. It's possibly effective for dental plaque and gingivitis, though the evidence is limited. However, bloodroot is potentially toxic and corrosive, and we don't recommend it for self-treatment.
Can slippery elm cause side effects?
Topical contact with slippery elm can cause contact dermatitis (a skin rash), and its pollen is an allergen. When taken by mouth for short-term use, it's generally well tolerated, but long-term safety data are limited.
What about bloodroot side effects?
Bloodroot can cause nausea, vomiting, and in high doses, very serious effects like low blood pressure, shock, or coma. Topical skin contact causes irritation, scarring, and severe pain. Long-term oral use has been linked to mouth sores, leukoplakia, taste problems, and tooth staining — we really don't recommend this ingredient for self-treatment.
Will this slow down my other medicines?
Yes. Slippery elm may slow how your body absorbs oral medications and lower the amount that reaches your bloodstream, which could make them less effective. Use the medication checker on this page to see if any of your drugs are affected.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Apoptosis Easy Digest Formula is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Apoptosis Easy Digest Formula label
Sources

Sources & How We Checked

Apoptosis Easy Digest Formula's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 20 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Slippery Elm 3 references
  1. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  2. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  3. Czarnecki D, Nixon R, Bekhor P, and et al. Delayed prolonged contact urticaria from the elm tree. Contact Dermatitis 1993;28:196-197. PubMed

See these in context on the Slippery Elm monograph →

Bloodroot 17 references
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  3. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  4. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  5. Tenenbaum, H., Dahan, M., and Soell, M. Effectiveness of a sanguinarine regimen after scaling and root planing. J Periodontol. 1999;70(3):307-311. PubMed
  6. Eversole, L. R., Eversole, G. M., and Kopcik, J. Sanguinaria-associated oral leukoplakia: comparison with other benign and dysplastic leukoplakic lesions. Oral Surg.Oral Med.Oral Pathol.Oral Radiol.Endod. 2000;89(4):455-464. PubMed
  7. Allen, C. L., Loudon, J., and Mascarenhas, A. K. Sanguinaria-related leukoplakia: epidemiologic and clinicopathologic features of a recently described entity. Gen.Dent. 2001;49(6):608-614.
  8. Kopczyk, R. A., Abrams, H., Brown, A. T., Matheny, J. L., and Kaplan, A. L. Clinical and microbiological effects of a sanguinaria-containing mouthrinse and dentifrice with and without fluoride during 6 months of use. J.Periodontol. 1991;62(10):617-622. PubMed
  9. Harper, D. S., Mueller, L. J., Fine, J. B., Gordon, J., and Laster, L. L. Clinical efficacy of a dentifrice and oral rinse containing sanguinaria extract and zinc chloride during 6 months of use. J.Periodontol. 1990;61(6):352-358. PubMed
  10. Kuftinec, M. M., Mueller-Joseph, L. J., and Kopczyk, R. A. Sanguinaria toothpaste and oral rinse regimen clinical efficacy in short- and long-term trials. J.Can.Dent.Assoc. 1990;56(7 Suppl):31-33.
  11. Frankos, V. H., Brusick, D. J., Johnson, E. M., Maibach, H. I., Munro, I., Squire, R. A., and Weil, C. S. Safety of Sanguinaria extract as used in commercial toothpaste and oral rinse products. J.Can.Dent.Assoc. 1990;56(7 Suppl):41-47.
  12. Cullinan, M. P., Powell, R. N., Faddy, M. J., and Seymour, G. J. Efficacy of a dentifrice and oral rinse containing sanguinaria extract in conjunction with initial periodontal therapy. Aust.Dent.J. 1997;42(1):47-51. PubMed
  13. Affleck, A. G. and Varma, S. A case of do-it-yourself Mohs' surgery using bloodroot obtained from the internet. Br.J Dermatol 2007;157(5):1078-1079. PubMed
  14. Cienki JJ, Zaret L. An Internet misadventure: bloodroot salve toxicity. J Altern Complement Med. 2010;16(10):1125-7. PubMed
  15. Hou JL, Brewer JD. Black salve and bloodroot extract in dermatologic conditions. Cutis. 2015;95(6):309-11.
  16. Schilling LM, Saedi N. Bloodroot paste: what dermatologists and patients need to know. Dermatol Surg 2016;42(10):1223-4. PubMed
  17. Schlichte MJ, Downing CP, Ramirez-Fort M, Gordon R, Tyring S. Bloodroot associated eschar. Dermatol Online J 2014;20(7). DOI

See these in context on the Bloodroot monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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