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Dietary supplement

Apple Cider Vinegar Ingredients & Drug Interactions

by Fresh Healthcare

Apple Cider Vinegar label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Apple Cider Vinegar against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Apple Cider Vinegar is a dietary supplement by Fresh Healthcare with 4 active ingredients. Its ingredients are commonly taken for blood sugar support, weight management, digestive upset.Based on those ingredients, 1,137 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Ginger, Ceylon Cinnamon, Cayenne Pepper. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Apple Cider Vinegar by Fresh Healthcare

Ask about any prescription or over-the-counter medication and we check it for interactions with Apple Cider Vinegar by Fresh Healthcare — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Apple Cider Vinegar by Fresh Healthcare

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 12, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 4 of its 4 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This capsule contains 4 active ingredients: apple cider vinegar, Ceylon cinnamon, ginger, and cayenne pepper. The product also includes two inactive ingredients — hydroxypropylmethyl cellulose and rice concentrate — which serve as capsule material and filler.

Each ingredient brings a traditional culinary or herbal role. Apple cider vinegar is the fermented juice of apples; Ceylon cinnamon is bark from the cinnamon tree native to Sri Lanka; ginger is the rhizome (underground stem) of the ginger plant; and cayenne pepper is ground from hot chili peppers.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Anti-inflammatory, anti-aging, and digestive support.
  • We looked for evidence on: Back pain, Dyspepsia, Diarrhea, Constipation, Irritable bowel syndrome (IBS), Joint pain — and 4 related terms.
  • The strongest evidence on file: Capsicum is rated "Possibly Effective" for Back pain (Natural Medicines).
  • Also on file: Ginger is rated "Possibly Ineffective" for Exercise-induced muscle soreness.
  • Also on file: Ceylon Cinnamon is rated "Insufficient Reliable Evidence To Rate" for Diarrhea, Dyspepsia, Irritable bowel syndrome (IBS).

The evidence is limited and mixed across these ingredients. Apple cider vinegar shows insufficient reliable evidence for acne, athletic performance, cognitive function, dental plaque, depression, and atopic dermatitis (eczema).

Ceylon cinnamon is possibly ineffective for obesity and diabetes, and has insufficient evidence for hay fever, COPD, and the common cold. Ginger fares somewhat better: it's possibly effective for pregnancy-related nausea and vomiting and period pain (dysmenorrhea), and possibly effective for osteoarthritis, though it's possibly ineffective for muscle soreness from exercise and chemotherapy-related nausea.

Cayenne pepper is likely effective for nerve pain after shingles (postherpetic neuralgia) and diabetic nerve pain, possibly effective for cluster headaches, back pain, and post-op nausea, but the data we hold doesn't establish an overall purpose for this combined formula.

The evidence, ingredient by ingredient Apple Cider Vinegar Ceylon Cinnamon Ginger Capsicum

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 4 of the 4 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 4 of 4.
  • General safety write-ups exist for 4 of 4.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

In typical food amounts, all four ingredients are generally well tolerated. However, the product's safety as a concentrated supplement at medicinal doses is less established.

Apple cider vinegar in large amounts or over long periods can cause serious side effects: a documented case involved hypokalemia, elevated renin levels, and osteoporosis after 6 years of daily use. Ceylon cinnamon at supplement doses is less studied than as a spice; the most common oral side effects are bloating, indigestion, and nausea.

One rare case of post-operative bleeding was reported after long-term daily use. Ginger is generally well tolerated at typical amounts, though doses above 5 grams daily increase the risk of abdominal discomfort, burping, diarrhea, and heartburn; encapsulated ginger may reduce these symptoms.

Cayenne pepper commonly causes belching, bloating, burning sensations, and diarrhea. Pregnancy and lactation data: Ceylon cinnamon is rated likely safe during pregnancy and likely safe during lactation.

Ginger is rated likely or possibly safe during both pregnancy and lactation. Cayenne pepper is rated likely safe during pregnancy and possibly or likely safe during lactation.

Apple cider vinegar's pregnancy and lactation data is incomplete in our files, so check with your doctor before using it during these periods.

Side effects, ingredient by ingredient Apple Cider Vinegar Ceylon Cinnamon Ginger Capsicum

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 4 of the 4 matched ingredients can interact with medications — Ceylon Cinnamon, Apple Cider Vinegar, Capsicum, Ginger.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications; heart-rhythm medications.
  • For scale: 1,138 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your pharmacist if you take blood thinners (warfarin, phenprocoumon, aspirin, or other anticoagulants or antiplatelet drugs), insulin or other diabetes medications, blood pressure drugs (especially ACE inhibitors, losartan, or nifedipine), diuretics (water pills), digoxin or other heart medications, theophylline, or ciprofloxacin. The ginger and cayenne pepper in particular interact with a broad range of drug-metabolizing pathways — your pharmacist can tell you if yours are affected.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product brings together four ingredients with real interactions — especially with blood thinners, blood pressure medications, diabetes drugs, and digoxin. If you take any prescription medication, run it through our checker before starting.

The supplement is generally tolerated at food-like amounts, but long-term use of concentrated doses carries some documented risks. Talk with your pharmacist about whether this blend is right for you and your medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 4 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 23, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Apple Cider Vinegar, straight from the product label.

Brand Fresh Healthcare
Barcode (UPC) X001XIUJOV
Net contents 120 Capsule(s)
Market status On market
Date entered into DSLD Jun 23, 2021
DSLD ID 248114
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Apple Cider Vinegar by Fresh Healthcare, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3 Capsule(s)
Maximum serving Sizes:
3 Capsule(s)
Servings per container
40
UPC/BARCODE
X001XIUJOV
IngredientAmount% DV
Apple Cider Vinegar1500 mg--
Ceylon Cinnamon150 mg--
Ginger75 mg--
Cayenne Pepper15 mg--

Other ingredients: Hydroxypropylmethyl Cellulose, Rice concentrate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

About Apple Cider Vinegar: Apple Cider Vinegar (ACV) is an incredible Superfood which has been used for centuries for its beneficial properties. Its main active ingredient is acetic acid and is made from apple cider that has undergone fermentation to form beneficial probiotics and enzymes. ACV has been shown to support healthy blood sugar levels, detox, digestion, and weight management. It also contains natural anti-inflammatory and antibacterial compounds which can support joint and skin health.Our Apple Cider Vinegar Complex contains Organic Ceylon Cinnamon, Ginger Root and Cayenne Pepper which compliment the anti-inflammatory, anti-aging and digestive properties of ACV. Our Apple Cider Vinegar Complex contains Organic Ceylon Cinnamon, Ginger Root and Cayenne Pepper which compliment the anti-inflammatory, anti-aging and digestive properties of ACV.

Premium apple cider vinegar

Apple cider vinegar with ginger, cinnamon powder & cayenne pepper

Formulation

Our Apple Cider Vinegar Complex contains Organic Ceylon Cinnamon, Ginger Root and Cayenne Pepper which compliment the anti-inflammatory, anti-aging and digestive properties of ACV.

1740mg per serving Max strength

Ultimate diet control

Supports blood sugar levels Supports healthy digestion Supports joint health & weight

Suitable for vegetarians

Suitable for vegetarian & vegans

GMP Good Manufacturing Practice Consistent Quality Manufactured in the USA Lab Verified 3rd Party Tested Pure & Potent

All Natural GMO FREE No artificial fillers

Suggested/Recommended/Usage/Directions

Suggested Use: Take three (3) capsules daily preferably with a meal or as recommended by a healthcare professional.

General Statements

Fresh body mind For free health hacks & discounts visit: www.freshbodymind.com

Best seller

Eco Friendly Manufacturer

Precautions

Keep out of the reach of children.

Do not use if safety seal is damaged or missing.

Caution: May cause GI discomfort in sensitive individuals. Do not exceed recommended dose.

Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.

Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.

Storage

Store at room temperature.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

GMP Good Manufacturing Practice Consistent Quality All Natural GMO FREE Manufactured in the USA Lab Verified 3rd Party Tested Pure & Potent

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Apple Cider Vinegar by Fresh Healthcare label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Apple Cider Vinegar label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Apple Cider Vinegar by Fresh Healthcare

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size3 Capsule(s) Dosage formCapsule Servings per container40 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Apple Cider Vinegar

Interacts with
162 drugs
1500 mg per serving

Apple cider vinegar is a fermented apple product that many people use hoping to help with blood sugar, weight, or digestion. The evidence for most of...

Apple Cider Vinegar monograph & interactions

Ceylon Cinnamon

Interacts with
258 drugs
150 mg per serving

Ceylon cinnamon is the so-called 'true' cinnamon, valued as a spice and used in traditional medicine for blood sugar, cholesterol, and digestion. Evid...

Ceylon Cinnamon monograph & interactions

Ginger

Interacts with
1,007 drugs
75 mg per serving

Ginger is a widely used culinary spice with a long history in traditional medicine, and it has the strongest evidence for helping with nausea and vomi...

Ginger monograph & interactions

Cayenne Pepper

Interacts with
239 drugs
15 mg per serving

Capsicum (chili pepper) contains capsaicin, which is best known and best studied as a topical treatment for certain types of pain. Topical capsaicin p...

Cayenne Pepper monograph & interactions

Other (inactive) ingredients: Hydroxypropylmethyl Cellulose, Rice concentrate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Apple Cider Vinegar by Fresh Healthcare Drug Interactions

Want to check YOUR meds against Apple Cider Vinegar?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
1,137Drugs
1,023 Moderate 114 Minor

Ingredients driving the most interactions

Ginger 1,007
Ceylon Cinnamon 258
Cayenne Pepper 239
Apple Cider Vinegar 162

Individual Drug Interactions

The ingredients in Apple Cider Vinegar interact with 1,137 drugs. Click any drug to see the details.

4 of the 4 ingredients in Apple Cider Vinegar interact with drugs. Each result below shows which ingredient is responsible. Ginger Ceylon Cinnamon Cayenne Pepper Apple Cider Vinegar

Each ingredient & the kinds of drugs it affects

For each ingredient in Apple Cider Vinegar with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Ginger14 drug types · 1,007 drugs

Anticoagulant/Antiplatelet Drugs

Ginger may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs. However, research is conflicting.
Laboratory research suggests that ginger inhibits thromboxane synthetase and decreases platelet aggregation. However, this has not been demonstrated unequivocally in humans, with mixed results from clinical trials. Theoretically, excessive amounts of ginger might increase the risk of bleeding when used with anticoagulant/antiplatelet drugs.

Likelihood Possible Evidence B
Antidiabetes Drugs

Theoretically, taking ginger with antidiabetes drugs might increase the risk of hypoglycemia.
Animal and human research suggests that ginger might increase insulin levels and/or decrease blood glucose levels.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Ginger might increase or decrease the levels of CYP3A4 substrates.
In vitro research and some case reports suggest that ginger inhibits CYP3A4 activity. Three case reports from the World Health Organization (WHO) adverse drug reaction database describe increased toxicity in patients taking ginger and cancer medications that are CYP3A4 substrates (imatinib, dabrafenib, and crizotinib). However, the causality of this interaction is unclear due to the presence of multiple interacting drugs and routes of administration.
Conversely, other in vitro research suggests that ginger induces CYP3A4 activity, leading to reduced levels of CYP3A4 substrates. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Losartan (Cozaar)

Theoretically, ginger might increase levels of losartan and the risk of hypotension.
In animal research, ginger increased the levels and hypotensive effects of a single dose of losartan. It is not clear if ginger alters the concentration or effects of losartan when taken continuously. Additionally, this interaction has not been shown in humans.

Likelihood Possible Evidence D
Nifedipine (Procardia)

Ginger may have antiplatelet effects and increase the risk of bleeding if used with nifedipine.
Clinical research shows that combined treatment with ginger 1 gram plus nifedipine 10 mg significantly inhibits platelet aggregation when compared to nifedipine or ginger alone.

Likelihood Possible Evidence B
P-Glycoprotein Substrates

Ginger might increase the absorption and blood levels of P-glycoprotein (P-gp) substrates.
In vitro research and case reports suggest that ginger inhibits drug efflux by P-gp, potentially increasing absorption and serum levels of P-gp substrates. Two case reports from the World Health Organization (WHO) adverse drug reaction database describe increased toxicity in patients taking ginger and cancer medications that are P-gp substrates (trametinib, crizotinib). However, the causality of this interaction is unclear due to the presence of multiple interacting drugs and routes of administration.

Likelihood Possible Evidence D
Phenprocoumon (Marcoumar, Others)

Ginger might increase the risk of bleeding with phenprocoumon.
Phenprocoumon, a warfarin-related anticoagulant, might increase the international normalized ratio (INR) when taken with ginger. There is one case report of a 76-year-old woman with a stable INR on phenprocoumon that increased to greater than 10 when she began consuming dried ginger and ginger tea.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Ginger might increase the risk of bleeding with warfarin.
Laboratory research suggests that ginger might inhibit thromboxane synthetase and decrease platelet aggregation. In one case report, ginger increased the INR when taken with phenprocoumon, which has similar pharmacological effects as warfarin. In another case report, ginger increased the INR when taken with a combination of warfarin, hydrochlorothiazide, and acetaminophen. A longitudinal analysis suggests that taking ginger increases the risk of bleeding in patients taking warfarin for at least 4 months. However, research in healthy people suggests that ginger has no effect on INR, or the pharmacokinetics or pharmacodynamics of warfarin. Until more is known, monitor INRs closely in patients taking large amounts of ginger.

Likelihood Possible Evidence B
Calcium Channel Blockers

Theoretically, taking ginger with calcium channel blockers might increase the risk of hypotension.
Some animal and in vitro research suggests that ginger has hypotensive and calcium channel-blocking effects. Another animal study shows that concomitant administration of ginger and the calcium channel blocker amlodipine leads to greater reductions in blood pressure when compared with amlodipine alone.

Likelihood Unlikely Evidence D
Cyclosporine (Neoral, Sandimmune)

Theoretically, when taken prior to cyclosporine, ginger might decrease cyclosporine levels.
In an animal model, ginger juice taken 2 hours prior to cyclosporine administration reduced the maximum concentration and area under the curve of cyclosporine by 51% and 40%, respectively. This effect was not observed when ginger juice and cyclosporine were administered at the same time.

Likelihood Possible Evidence D
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, ginger might increase the levels of CYP1A2 substrates.
In vitro research shows that ginger inhibits CYP1A2 activity. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2B6 (Cyp2B6) Substrates

Theoretically, ginger might increase the levels of CYP2B6 substrates.
In vitro research shows that ginger inhibits CYP2B6 activity. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, ginger might increase the levels of CYP2C9 substrates.
In vitro research shows that ginger inhibits CYP2C9 activity. However, this interaction has not been reported in humans.

Likelihood Possible Evidence D
Metronidazole (Flagyl)

Theoretically, ginger might increase levels of metronidazole.
In an animal model, ginger increased the absorption and plasma half-life of metronidazole. In addition, the elimination rate and clearance of metronidazole was significantly reduced.

Likelihood Possible Evidence D
Ginger full monograph & interactions

Ceylon Cinnamon2 drug types · 258 drugs

Antidiabetes Drugs

Theoretically, Ceylon cinnamon may have additive effects with antidiabetes drugs.
Ceylon cinnamon may lower blood glucose levels. Dose adjustments might be necessary.

Likelihood Possible Evidence D
Antihypertensive Drugs

Theoretically, Ceylon cinnamon might have additive effects with antihypertensive drugs and increase the risk of hypotension.
Animal research shows that Ceylon cinnamon extract has vasorelaxant properties and reduces blood pressure in rat models of hypertension, possibly via inhibition of calcium influx through L-type voltage-sensitive channels.

Likelihood Possible Evidence D
Ceylon Cinnamon full monograph & interactions

Cayenne Pepper6 drug types · 239 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, capsicum may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
In vitro research shows that capsicum might increase the effects of antiplatelet drugs. Also, population research shows that capsicum is associated with an increased risk of self-reported bleeding in patients taking warfarin. However, clinical research shows that taking a single dose of capsaicin (Asian Herbex Ltd.), the active ingredient in capsicum, 400-800 mcg orally in combination with aspirin 500 mg does not decrease platelet aggregation when compared with taking aspirin 500 mg alone. Also, there was no notable effect on measures of platelet aggregation with capsaicin. It is unclear whether capsaicin must be used in more than a single dose to affect platelet aggregation.

Likelihood Possible Evidence B
Antidiabetes Drugs

Theoretically, taking capsicum with antidiabetes drugs might increase the risk of hypoglycemia.
Preliminary clinical research shows that consuming capsicum 5 grams along with a glucose drink attenuates the rise in plasma glucose after 30 minutes by 21%, decreases the 2-hour postprandial area under the curve of plasma glucose by 11%, and increases the 2-hour postprandial area under the curve of plasma insulin by 58% in healthy individuals when compared with placebo. Other clinical research shows that taking capsicum 5 mg daily for 28 days significantly reduces postprandial blood glucose and insulin levels, but not fasting blood glucose and insulin levels, in patients with gestational diabetes.

Likelihood Possible Evidence B
Aspirin

Theoretically, taking capsicum with aspirin might reduce the bioavailability of aspirin.
Animal research shows that acute or chronic intake of capsicum pepper reduces oral aspirin bioavailability. This has not been shown in humans.

Likelihood Possible Evidence D
Theophylline

Theoretically, taking capsicum with theophylline might increase the levels and adverse effects of theophylline.
In animal research, oral administration of capsicum reduced excretion of theophylline. However, capsicum does not seem to affect the pharmacokinetics of theophylline when administered intravenously.

Likelihood Possible Evidence D
Ace Inhibitors (Aceis)

Theoretically, using topical capsaicin may increase the risk of ACE inhibitor-induced cough.
There is one case report of a topically applied capsaicin cream contributing to the cough reflex in a patient using an ACEI. However, it is unclear if this interaction is clinically significant.

Likelihood Unlikely Evidence D
Ciprofloxacin (Cipro)

Theoretically, taking capsicum with ciprofloxacin might increase levels and adverse effects of ciprofloxacin.
Animal research shows that concomitant use of capsaicin, the active constituent of capsicum, and ciprofloxacin increases the bioavailability of ciprofloxacin by up to 70%.

Likelihood Possible Evidence D
Cayenne Pepper full monograph & interactions

Apple Cider Vinegar4 drug types · 162 drugs

Digoxin (Lanoxin)

Theoretically, concomitant use of apple cider vinegar with digoxin might increase the risk of cardiac toxicity.
A case of hypokalemia related to chronic use of apple cider vinegar has been reported. Theoretically, overuse of apple cider vinegar could decrease potassium levels, increasing the risk of toxicity with digoxin.

Likelihood Possible Evidence D
Diuretic Drugs

Theoretically, concomitant use of apple cider vinegar with diuretic drugs might increase the risk of hypokalemia.
A case of hypokalemia related to chronic use of apple cider vinegar has been reported. There is some concern that people taking apple cider vinegar along with potassium depleting diuretics might have an increased risk for hypokalemia.

Likelihood Possible Evidence D
Insulin

Theoretically, concomitant use of apple cider vinegar with insulin might increase the risk of hypokalemia.
A case of hypokalemia related to chronic use of apple cider vinegar has been reported. Theoretically, overuse of apple cider vinegar concomitantly with insulin might increase the risk of hypokalemia.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, taking apple cider vinegar with antidiabetes drugs might increase the risk of hypoglycemia.
Apple cider vinegar might reduce fasting and postprandial blood glucose levels and decrease gastric emptying in people with diabetes. However, not all research agrees. Theoretically, it might have additive effects on glucose levels when used with antidiabetes drugs.

Likelihood Possible Evidence B
Apple Cider Vinegar full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Apple Cider Vinegar, from the product label.

Fresh Healthcare

See all Fresh Healthcare products
Name
Fresh Healthcare
Street Address
3422 SW 15 Street Suite #9169
City
Deerfield Beach
State
FL
ZipCode
33442
Web Address
www.freshbodymind.com
Pharmacist Counseling Corner

Apple Cider Vinegar by Fresh Healthcare: Common Questions

Does Apple Cider Vinegar by Fresh Healthcare interact with any medications?
Yes. Based on its ingredients, Apple Cider Vinegar has a known interaction with 1,137 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Apple Cider Vinegar contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does ginger in this product actually help with nausea?
Ginger alone is possibly effective for pregnancy-related nausea and vomiting and for period pain (dysmenorrhea), so it may help with some types of nausea. However, we don't have evidence that this full formula works for any single condition. Your experience will depend on the dose and whether the other ingredients help or interfere.
Will this give me stomach upset?
All four ingredients can cause gastrointestinal side effects — ginger and cayenne pepper are common culprits for heartburn, diarrhea, and abdominal discomfort, and Ceylon cinnamon can cause bloating and indigestion. Encapsulated ginger may cause fewer of these symptoms than powdered forms. Start with a small dose if you have a sensitive stomach.
Is it safe to take while pregnant?
Ceylon cinnamon, ginger, and cayenne pepper are rated likely or possibly safe during pregnancy at typical amounts. Apple cider vinegar's safety in pregnancy isn't established in our data. Because this is a blend and you're carrying a baby, talk with your doctor or midwife before starting it — they know your full health picture.
Can I take this with my blood pressure medicine?
Both Ceylon cinnamon and ginger (and potentially cayenne pepper) may lower blood pressure or have additive effects with blood pressure medications. This could cause your pressure to drop too low. Check with your pharmacist before combining them — your dose may need adjustment.
What does 'apple cider vinegar' in a capsule actually contain?
The capsule contains fermented apple juice that's been processed into a supplement form. We don't have the concentration details, so it's likely more potent than food-strength vinegar — which matters because concentrated amounts carry more risk of side effects, including low potassium levels with long-term use.
Is there anything in this product I'm allergic to?
We can't predict individual allergies, but Ceylon cinnamon and cayenne pepper can cause allergic skin reactions or dermatitis in sensitive people. If you have a known sensitivity to any spice or capsicum, skip this product or patch-test first. Talk to your pharmacist if you're unsure.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Apple Cider Vinegar is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Apple Cider Vinegar label
Go deeper

The Full Monographs Behind Apple Cider Vinegar’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Apple Cider Vinegar

Interacts with 162 drugs

Apple cider vinegar is a fermented apple product that many people use hoping to help with blood sugar, weight, or digestion. The evidence for most of these uses is limited and mixed, and the...

Read the full Apple Cider Vinegar monograph → Herb & supplement monograph

Ceylon Cinnamon

Interacts with 258 drugs

Ceylon cinnamon is the so-called 'true' cinnamon, valued as a spice and used in traditional medicine for blood sugar, cholesterol, and digestion. Evidence for most health benefits is limited...

Read the full Ceylon Cinnamon monograph → Herb & supplement monograph

Ginger

Interacts with 1,007 drugs

Ginger is a widely used culinary spice with a long history in traditional medicine, and it has the strongest evidence for helping with nausea and vomiting, including from motion sickness, pr...

Read the full Ginger monograph → Herb & supplement monograph

Capsicum

Interacts with 239 drugs

Capsicum (chili pepper) contains capsaicin, which is best known and best studied as a topical treatment for certain types of pain. Topical capsaicin products are supported by reasonable evid...

Read the full Capsicum monograph →
Sources

Sources & How We Checked

Apple Cider Vinegar's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 186 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Apple Cider Vinegar 11 references
  1. Lhotta K, Hofle G, Gasser R, Finkenstedt G. Hypokalemia, hyperreninemia, and osteoporosis in a patient ingesting large amounts of cider vinegar. Nephron 1998;80:242-3. PubMed
  2. Hill LL, Woodruff LH, Foote JC, Barreto-Alcoba M. Esophageal injury by apple cider vinegar tablets and subsequent evaluation of products. J Am Diet Assoc 2005;105:1141-4. PubMed
  3. Hlebowicz J, Darwiche G, Björgell O, Almér LO. Effect of apple cider vinegar on delayed gastric emptying in patients with type 1 diabetes mellitus: a pilot study. BMC Gastroenterol 2007;7:46. PubMed
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Ceylon Cinnamon 22 references
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Ginger 64 references
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Capsicum 89 references
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

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