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Dietary supplement

Aronia 20:1 Concentrated Extract Ingredients & Drug Interactions

by Samsara Herbs

Powder Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Aronia 20:1 Concentrated Extract is a dietary supplement by Samsara Herbs with 1 active ingredient. Its ingredients are commonly taken for antioxidant support, heart and blood vessel health, blood pressure support.Based on those ingredients, 811 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Aronia melanocarpa. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Aronia 20:1 Concentrated Extract by Samsara Herbs

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: aronia melanocarpa, also called chokeberry, in a 20:1 concentrated extract form. That ratio means the powder is made by concentrating the berry to remove water and increase potency.

There are no inactive ingredients listed.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Chokeberry's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: supports healthy immune response.
  • We looked for evidence on: Cancer, Cardiovascular disease (CVD), Diabetes, Hypercholesterolemia, Hypertension, Rheumatoid arthritis (RA) — and 4 related terms.
  • The closest evidence on file: Chokeberry is rated "Possibly Ineffective" for Cardiovascular disease (CVD) (Natural Medicines).
  • Also on file: Chokeberry is rated "Insufficient Reliable Evidence To Rate" for Cancer, Diabetes, Hypercholesterolemia, Hypertension, and more.

The evidence for chokeberry's effectiveness is mixed and limited. For cardiovascular disease, the data suggests it's possibly ineffective.

For age-related cognitive decline, age-related macular degeneration (AMD), athletic performance, and cancer, there isn't enough reliable evidence to know whether it works. Most of the research on chokeberry's benefits comes from food-form studies or lab work, not from the concentrated supplements like this one.

The evidence, ingredient by ingredient Chokeberry

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Chokeberry is generally well tolerated as a food, but safety information for concentrated supplement amounts is limited — we don't have strong data on how safe this extract form is at the doses people typically use. The most common side effects when taken orally are constipation, diarrhea, nausea, stomach cramps, and vomiting.

In one small study, about 14% of people reported digestive issues drinking 100 mL of chokeberry juice daily for 90 days; in another study, about 53% reported diarrhea, loss of appetite, nausea, stomach pain, or vomiting at twice that dose over 6 weeks. Pregnancy and breastfeeding safety data isn't on file for this ingredient.

Side effects, ingredient by ingredient Chokeberry

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Chokeberry.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 812 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check whether you take blood thinners or antiplatelet drugs (warfarin, aspirin, clopidogrel), drugs that lower blood sugar, trabectedin (a cancer medication), or any other medications metabolized by your liver's CYP3A4 enzyme — chokeberry may affect how these drugs work. If you take any prescription medications at all, it's worth running them through the checker on this page.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

If you take blood thinners, diabetes medication, or any CYP3A4 substrate drugs, you'll want to check with your pharmacist before starting this product. Even if you don't take those medications, the concentrated extract form hasn't been studied much, so use caution.

Chokeberry as food is safe for most people, but concentrated supplements are a different story — talk to your pharmacist or doctor about whether it's right for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 24, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Aronia 20:1 Concentrated Extract, straight from the product label.

Brand Samsara Herbs
Barcode (UPC) X000ZZ7WQV
Net contents 8 Ounce(s); 227 Gram(s)
Market status On market
Date entered into DSLD Oct 24, 2024
DSLD ID 319932
Product type Botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Aronia 20:1 Concentrated Extract by Samsara Herbs, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2850 Milligram(s)
Maximum serving Sizes:
2850 Milligram(s)
Servings per container
80
UPC/BARCODE
X000ZZ7WQV
IngredientAmount% DV
Aronia melanocarpa2850 mg--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Full Spectrum

Full Spectrum herbal extracts are made by concentrating the herb into an extract form, while maintaining all of its original compounds. The ideal choice for those wanting a more potent version of a complete herbal powder.

Proudly Manufactured in Utah, USA, in a 3rd party audited cGMP facility for Samsara Herbs Inc.

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

GMP Good Manufacturing Practice USA Tested 3rd party USA tested

General Statements

About us At Samsara Herbs, we believe that all positive change in the world must first begin with positive change from within. We invite you to tap into your own infinite power through the use of our potent herbal extracts! We seek out only quality herbs from our trusted sources from around the world for use in our herbal extracts. Samsara Herbs, dedicated to empowering your life force!

Formula

Description Aronia, also known as “Chokeberry”, is a hardy shrub, which is impervious to most plant diseases. It contains one of the highest ORAC counts of any plant in nature. It is a superfood which supports healthy immune response.

Suggested/Recommended/Usage/Directions

Our water soluble herbal extracts are best mixed in juice or a smoothie, although mixing in water is perfectly fine if you can tolerate the taste.

Suggested Use: Take 1 Scoop 1-3 times per day or as recommended by your health care professional.

Storage

Storage Cool dry place, out of direct sunlight.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Precautions

Caution: If you have a medical condition, are pregnant or taking medications, consult your hearth care professional before using this product.

Keep out of reach of children.

See for yourself

Aronia 20:1 Concentrated Extract by Samsara Herbs label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Aronia 20:1 Concentrated Extract by Samsara Herbs

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2850 Milligram(s) Dosage formPowder Servings per container80 Amounts shown are per serving.

Aronia melanocarpa

Interacts with
811 drugs
2850 mg per serving

Chokeberry (aronia) is a dark berry rich in antioxidants called polyphenols, and it's widely eaten as juice, jam, and supplements. Early research hint...

Aronia melanocarpa monograph & interactions
Interaction report

Aronia 20:1 Concentrated Extract by Samsara Herbs Drug Interactions

Want to check YOUR meds against Aronia 20:1 Concentrated Extract?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
811Drugs
811 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Aronia 20:1 Concentrated Extract with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Aronia melanocarpa4 drug types · 811 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, chokeberry might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Clinical and in vitro research suggests that chokeberry extract can temporarily inhibit platelet aggregation and decrease clot formation.

Likelihood Possible Evidence B
Antidiabetes Drugs

Theoretically, chokeberry might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Some clinical research shows that chokeberry decreases levels of blood glucose in some patients with diabetes. However, other clinical research suggests that chokeberry has no significant effect on blood glucose levels.

Likelihood Possible Evidence B
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, chokeberry might increase levels of drugs metabolized by CYP3A4.
In vitro research shows that chokeberry inhibits CYP3A4. In humans, there is one case report of a drug interaction with trabectedin, a CYP3A4 substrate, which is hypothesized to have been caused by chokeberry inhibition of CYP3A4.

Likelihood Possible Evidence D
Trabectedin (Yondelis)

Theoretically, chokeberry might increase the effects and adverse effects of trabectedin.
In one case report, a patient drinking chokeberry juice developed rhabdomyolysis induced by trabectedin, a cytochrome P450 3A4 (CYP3A4) substrate. It is possible that inhibition of CYP3A4 by chokeberry juice might have inhibited the metabolism of trabectedin and increased trabectedin levels in this patient.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Aronia 20:1 Concentrated Extract, from the product label.

Samsara Herbs

See all Samsara Herbs products
Name
Samsara Herbs Inc.
Street Address
PO Box 160215
City
Clearfield
State
Utah
ZipCode
84016
Phone Number
1-844-972-6727
Web Address
www.SamsaraHerbs.com
Pharmacist Counseling Corner

Aronia 20:1 Concentrated Extract by Samsara Herbs: Common Questions

Does Aronia 20:1 Concentrated Extract by Samsara Herbs interact with any medications?
Yes. Based on its ingredients, Aronia 20:1 Concentrated Extract has a known interaction with 811 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Aronia 20:1 Concentrated Extract contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is aronia, and why is it in this product?
Aronia is also called chokeberry — a dark berry sometimes used in juices and supplements. This product concentrates it to a 20:1 ratio, meaning it's a potent extract form. The reason people take it is for potential health benefits, though the evidence for most claimed uses is limited or mixed.
What side effects should I expect?
The most common side effects are digestive — constipation, diarrhea, nausea, stomach cramps, or vomiting. In small studies, 14–53% of people reported these depending on the dose and how long they took it. Most people tolerate it okay, but some have real stomach trouble.
Does this actually work for heart health or anything else?
For cardiovascular disease, the data suggests it's probably not effective. For cognitive decline, macular degeneration, athletic performance, and cancer, there just isn't enough reliable evidence in our data to know either way. Most benefit claims come from food-form studies, not from concentrated extracts like this.
Is this safe in pregnancy or while breastfeeding?
We don't have safety information on file for chokeberry in pregnancy or breastfeeding. Since this is a concentrated supplement extract and safety data is limited even for general use, talk with your doctor or pharmacist for personalized advice before taking it.
How is this different from eating chokeberries or drinking chokeberry juice?
This is a 20:1 concentrated powder — much more potent than the fresh fruit or juice. While chokeberry as food is generally well tolerated, concentrated supplements haven't been studied as thoroughly, so we know less about long-term safety at extract doses.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Aronia 20:1 Concentrated Extract is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Aronia 20:1 Concentrated Extract label
Go deeper

The Full Monographs Behind Aronia 20:1 Concentrated Extract’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Aronia 20:1 Concentrated Extract's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 8 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Chokeberry 8 references
  1. Sikora J, Broncel M, Markowicz M, Chalubinski M, Wojdan K, Mikiciuk-Olasik E. Short-term supplementation with Aronia melanocarpa extract improves platelet aggregation, clotting, and fibrinolysis in patients with metabolic syndrome. Eur J Nutr. 2012 Aug;51 PubMed
  2. Simeonov SB, Botushanov NP, Karahanian EB, Pavlova MB, Husianitis HK, Troev DM. Effects of Aronia melanocarpa juice as part of the dietary regimen in patients with diabetes mellitus. Folia Med (Plovdiv). 2002;44(3):20-3.
  3. Savikin K, Menkovic N, Zdunic G, Pljevljakusic D, Spasic S, Kardum N, Konic-Ristic A. Dietary supplementation with polyphenol-rich chokeberry juice improves skin morphology in cellulite. J Med Food. 2014 May;17(5):582-7. PubMed
  4. Bräunlich M, Christensen H, Johannesen S, Slimestad R, Wangensteen H, Malterud KE, Barsett H. In vitro inhibition of cytochrome P450 3A4 by Aronia melanocarpa constituents. Planta Med. 2013 Jan;79(2):137-41. PubMed
  5. Strippoli S, Lorusso V, Albano A, Guida M. Herbal-drug interaction induced rhabdomyolysis in a liposarcoma patient receiving trabectedin. BMC Complement Altern Med. 2013 Jul 30;13:199. PubMed
  6. Ryszawa N, Kawczynska-Drózdz A, Pryjma J, Czesnikiewicz-Guzik M, Adamek-Guzik T, Naruszewicz M, Korbut R, Guzik TJ. Effects of novel plant antioxidants on platelet superoxide production and aggregation in atherosclerosis. J Physiol Pharmacol. 2006 Dec;57(
  7. Milutinovic M, Velickovic Radovanovic R, Savikin K, et al. Chokeberry juice supplementation in type 2 diabetic patients - impact on health status. J Appl Biomed 2019;17(4):218-224. PubMed
  8. Lackner S, Sconocchia T, Ziegler T, et al. Immunomodulatory effects of aronia juice polyphenols-results of a randomized placebo-controlled human intervention study and cell culture experiments. Antioxidants (Basel) 2022;11(7):1283. PubMed

See these in context on the Chokeberry monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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