Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Ashitaba Ingredients & Drug Interactions

by Samsara Herbs

Ashitaba label
See full label image
Powder Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Ashitaba against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Ashitaba is a dietary supplement by Samsara Herbs with 1 active ingredient. Its ingredients are commonly taken for general wellness and longevity, antioxidant support, heart and cholesterol health.Based on those ingredients, 186 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Ashitaba. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Ashitaba by Samsara Herbs

Ask about any prescription or over-the-counter medication and we check it for interactions with Ashitaba by Samsara Herbs — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
Prefer a human? Send your question to our licensed pharmacists — free, answered by email within 24 hours.

HelloPharmacist Scorecard of Ashitaba by Samsara Herbs

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 16, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Ashitaba by Samsara Herbs contains one active ingredient: ashitaba, a leafy plant used in traditional herbal practice. There are no other inactive ingredients listed.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Ashitaba product and its label doesn't state a use — see Ashitaba's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence we have doesn't yet support using ashitaba for alcohol-related liver disease — the data is simply insufficient to say whether it works or doesn't. If you're considering this supplement for that reason, talk it over with your doctor about what's actually proven to help.

The evidence, ingredient by ingredient Ashitaba

How safe is it?

Some data gaps
Safety Information · database check
Some gaps

Safety data exists for these ingredients, but with some important gaps.

Why this rating?
  • We hold adverse-effect (side-effect) data for 0 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Ashitaba is likely safe when used as a food. As a concentrated supplement, though, its safety hasn't been well studied, so we're cautious about its long-term use.

The safety data during pregnancy and breastfeeding is too thin to recommend it — there isn't enough information to know whether it's safe, so talk with your doctor or pharmacist for personalized advice if you're pregnant, planning to become pregnant, or breastfeeding.

Side effects, ingredient by ingredient Ashitaba

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Ashitaba.
  • The most serious interaction on file is rated Moderate.
  • For scale: 186 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take any medications that are processed by the enzyme CYP1A2 — including certain pain relievers, heart medications, and blood pressure drugs — check your specific medications with the search tool before starting ashitaba. The interaction is Moderate in severity and hasn't been studied in people yet, so caution is warranted.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and some safety-information gaps remain.

Ashitaba is a traditional plant supplement with one active ingredient, but the evidence for it treating liver disease isn't established. The main concern is a potential interaction with medications your liver processes — affecting a large number of common drugs.

Before you start, check your medications with the search tool on this page and talk it over with your doctor or pharmacist.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated May 22, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Ashitaba, straight from the product label.

Brand Samsara Herbs
Barcode (UPC) X000WDRJ4V
Net contents 16 Ounce(s); 454 Gram(s); 1 Pound(s)
Market status On market
Date entered into DSLD May 22, 2020
DSLD ID 220330
Product type Botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Ashitaba by Samsara Herbs, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2.68 Gram(s)
Maximum serving Sizes:
2.68 Gram(s)
Servings per container
171
UPC/BARCODE
X000WDRJ4V
IngredientAmount% DV
Ashitaba2680 mg--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Ashitaba 20:1 Concentrated extract Full Spectrum

Description Ashitaba is a native to Hachijo Jima, a small volcanic island off the coast of Japan. Young Ashitaba leaves and stems, as well as the plant’s roots, have been an integral part of the diet of the island's residents, who are known to have one of the longest life expectancies on the plant. These residents have referred to Ashitaba as the "longevity herb.”

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

GMP Good Manufacturing Practice USA Tested 3rd party USA tested

General Statements

About us At Samsara Herbs, we believe that all positive change in the world must first begin with positive change from within. We invite you to tap into your own infinite power through the use of our potent herbal extracts! We seek out only quality herbs from our trusted sources from around the world for use in our herbal extracts. Samsara Herbs, dedicated to empowering your life force!

Formulation

Full Spectrum herbal extracts are made by concentrating the herb into an extract form, while maintaining all of its original compounds. The ideal choice for those wanting a more potent version of a complete herbal powder.

Suggested/Recommended/Usage/Directions

Our water soluble herbal extracts are best mixed in juice or a smoothie, although mixing in water is perfectly fine if you can tolerate the taste.

Suggested Use: Take 1 Scoop 1-3 times per day or as recommended by your health care professional.

Storage

Storage Cool dry place, out of direct sunlight.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Precautions

Caution: If you have a medical condition, are pregnant or taking medications, consult your hearth care professional before using this product.

Keep out of reach of children.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Ashitaba by Samsara Herbs label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Ashitaba label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Ashitaba by Samsara Herbs

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2.68 Gram(s) Dosage formPowder Servings per container171 Amounts shown are per serving.

Ashitaba

Interacts with
186 drugs
2680 mg per serving

Ashitaba is a leafy plant from Japan that is eaten as a vegetable and taken as a supplement for general health, antioxidant, and heart benefits. Most...

Ashitaba monograph & interactions
Interaction report

Ashitaba by Samsara Herbs Drug Interactions

Want to check YOUR meds against Ashitaba?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
186Drugs
186 Moderate

Ingredients driving the most interactions

Ashitaba 186

Individual Drug Interactions

The ingredients in Ashitaba interact with 186 drugs. Click any drug to see the details.

1 of the 1 ingredient in Ashitaba interact with drugs. Each result below shows which ingredient is responsible. Ashitaba

Each ingredient & the kinds of drugs it affects

For each ingredient in Ashitaba with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Ashitaba1 drug type · 186 drugs

Cytochrome P450 1A2 (Cyp1A2) Substrates

In vitro research shows that ashitaba extract inhibits cytochrome P450 (CYP) 1A2. Theoretically, concomitant use of ashitaba with CYP1A2 substrates might decrease the clearance of these substrates and increase the risk for adverse effects. However, this interaction has yet to be reported in humans. Until more is known, use with caution.

Likelihood Possible Evidence D
Ashitaba full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Ashitaba, from the product label.

Samsara Herbs

See all Samsara Herbs products
Name
Aspen Copacking
Street Address
810 North 2800 West
City
Lindon
State
Utah
ZipCode
84042
Pharmacist Counseling Corner

Ashitaba by Samsara Herbs: Common Questions

Does Ashitaba by Samsara Herbs interact with any medications?
Yes. Based on its ingredients, Ashitaba has a known interaction with 186 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Ashitaba contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I use ashitaba while pregnant or breastfeeding?
There isn't enough safety data on ashitaba in pregnancy or while breastfeeding to say whether it's safe. Talk with your doctor or pharmacist about whether it's right for you in these situations.
Does ashitaba actually work for liver disease?
The evidence we have for ashitaba and alcohol-related liver disease isn't strong enough to say it works. There simply aren't enough reliable studies, so don't count on it as a treatment.
What is ashitaba and what does it do?
Ashitaba is a leafy plant used in traditional herbal medicine. It's likely safe as a food, but its safety and effects as a concentrated supplement haven't been well studied.
Does ashitaba interact with a lot of medications?
Lab studies suggest ashitaba can slow how your body clears certain drugs, which affects a large number of common medications. However, this interaction hasn't been reported in people yet — we just don't have the data. Check your specific medications on this page before you start.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Ashitaba is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Ashitaba label
Go deeper

The Full Monographs Behind Ashitaba’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Ashitaba

Interacts with 186 drugs

Ashitaba is a leafy plant from Japan that is eaten as a vegetable and taken as a supplement for general health, antioxidant, and heart benefits. Most of the supporting research comes from la...

Read the full Ashitaba monograph →
Sources

Sources & How We Checked

Ashitaba's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 2 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Ashitaba 2 references
  1. Kwon D, Yoon S, Carter O, Bailey GS, Dashwood RH. Antioxidant and antigenotoxic activities of Angelica keiskei, Oenanthe javanica and Brassica oleracea in the Salmonella mutagenicity assay and in HCT116 human colon cancer cells. Biofactors. 2006;26(4):231
  2. Noh HM, Ahn EM, Yun JM, Cho BL, Paek YJ. Angelica keiskei Koidzumi extracts improve some markers of liver function in habitual alcohol drinkers: a randomized double-blind clinical trial. J Med Food. 2015;18(2):166-72.

See these in context on the Ashitaba monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

Keep exploring
Supplement interaction checker › Check any supplement or product against your medications Drug–drug interactions › Check two or more of your medications against each other Browse medications A–Z › Every drug we've checked against herbs & supplements NDC & pricing lookup › Find a drug’s NDCs, packaging and costs Ask a pharmacist › Free, personal answer from our licensed team