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Dietary supplement

Sida Acuta Ingredients & Drug Interactions

by Samsara Herbs

Sida Acuta label
See full label image
Powder Category: Botanical
Most serious interaction: Major
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Sida Acuta against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Major

Sida Acuta is a dietary supplement by Samsara Herbs with 1 active ingredient. Its ingredients are commonly taken for weight loss and energy, asthma and breathing problems, joint and muscle pain.Based on those ingredients, 445 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Sida acuta. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Sida Acuta by Samsara Herbs

Ask about any prescription or over-the-counter medication and we check it for interactions with Sida Acuta by Samsara Herbs — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Sida Acuta by Samsara Herbs

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Sep 10, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: Sida acuta (labeled under its related monograph as Sida cordifolia). It's a plant extract that contains ephedrine, a central nervous system stimulant.

The powder form has no inactive ingredients listed.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

We hold no graded evidence for this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: maintain healthy immune response and blood health.
  • Our graded evidence for these ingredients doesn't cover that particular purpose.

We hold no effectiveness ratings for Sida acuta in our data, so we cannot tell you what it's meant to do or whether it works for its intended use.

The evidence, ingredient by ingredient Sida Cordifolia

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Sida acuta is not safe to use. It contains ephedrine, a stimulant linked to serious heart and blood pressure risks and banned in many products.

The safety data rates it as likely unsafe during pregnancy and breastfeeding — ephedrine can harm a nursing baby if it passes into breast milk. Ephedrine-containing products have been tied to dizziness, restlessness, irritability, trouble concentrating, insomnia, headache, loss of appetite, anxiety, and even psychosis or personality changes.

Long-term or high-dose use can lead to dependence and tolerance. Most concerning are cardiovascular side effects: heart rhythm abnormalities, palpitations, increased heart rate, high blood pressure, heart inflammation, heart attack, stroke, and sudden cardiac death have all been reported with ephedrine products.

Side effects, ingredient by ingredient Sida Cordifolia

Meds to double-check

Major interaction found
Known Interaction Concern · database check
Major identified

At least one ingredient has a documented Major-severity interaction. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Sida Cordifolia.
  • The most serious interaction on file is rated Major.
  • Some involve high-stakes drug classes: diabetes medications; heart-rhythm medications.
  • For scale: 445 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your doctor or pharmacist if you take QT interval-prolonging drugs (heart rhythm medications), stimulants, caffeine or other methylxanthines, antidiabetes drugs, ergot derivatives, dexamethasone, or monoamine oxidase inhibitors (MAOIs). The interactions are rated Major or Moderate and could affect your heart rhythm, blood pressure, blood sugar, or medication effectiveness.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Major medication interactions have been identified, and safety information is well characterized.

This product carries substantial risks due to its ephedrine content — particularly for your heart and blood pressure. If you're taking any medications (especially for the heart, blood sugar, or mood), or if you're pregnant or breastfeeding, do not take this without talking to your doctor or pharmacist first.

The safety concerns here are serious enough that many people should avoid it altogether.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated May 22, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Sida Acuta, straight from the product label.

Brand Samsara Herbs
Barcode (UPC) X0019H6ZBH
Net contents 4 Ounce(s); 114 Gram(s)
Market status On market
Date entered into DSLD May 22, 2020
DSLD ID 221016
Product type Botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Sida Acuta by Samsara Herbs, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3.015 Gram(s)
Maximum serving Sizes:
3.015 Gram(s)
Servings per container
38
UPC/BARCODE
X0019H6ZBH
IngredientAmount% DV
Sida acuta3015 mg--

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Sida Acuta 20:1 Concentrated extract

Description Also known as Wireweed, Sida Acuta has, historically, been used for maintaining healthy immune response. It is also believed to support blood health in a wide range of areas.

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

GMP Good Manufacturing Practice USA Tested 3rd party USA tested

General Statements

About us At Samsara Herbs, we believe that all positive change in the world must first begin with positive change from within. We invite you to tap into your own infinite power through the use of our potent herbal extracts! We seek out only quality herbs from our trusted sources from around the world for use in our herbal extracts. Samsara Herbs, dedicated to empowering your life force!

Formulation

Full Spectrum herbal extracts are made by concentrating the herb into an extract form, while maintaining all of its original compounds. The ideal choice for those wanting a more potent version of a complete herbal powder.

Suggested/Recommended/Usage/Directions

Our water soluble herbal extracts are best mixed in juice or a smoothie, although mixing in water is perfectly fine if you can tolerate the taste.

Suggested Use: Take 1 Scoop 1-3 times per day or as recommended by your health care professional.

Storage

Storage Cool dry place, out of direct sunlight.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Precautions

Caution: If you have a medical condition, are pregnant or taking medications, consult your hearth care professional before using this product.

Keep out of reach of children.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Sida Acuta by Samsara Herbs label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Sida Acuta label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Sida Acuta by Samsara Herbs

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size3.015 Gram(s) Dosage formPowder Servings per container38 Amounts shown are per serving.

Sida acuta

Interacts with
445 drugs
3015 mg per serving

Sida cordifolia (bala or country mallow) is a traditional Ayurvedic plant that naturally contains ephedrine, a powerful stimulant. Because of this, ma...

Sida acuta monograph & interactions
Interaction report

Sida Acuta by Samsara Herbs Drug Interactions

Want to check YOUR meds against Sida Acuta?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
445Drugs
337 Major 108 Moderate

Ingredients driving the most interactions

Sida acuta 445

Individual Drug Interactions

The ingredients in Sida Acuta interact with 445 drugs. Click any drug to see the details.

1 of the 1 ingredient in Sida Acuta interact with drugs. Each result below shows which ingredient is responsible. Sida acuta

Each ingredient & the kinds of drugs it affects

For each ingredient in Sida Acuta with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Sida acuta7 drug types · 445 drugs

Methylxanthines

Theoretically, Sida cordifolia might increase the risk of serious adverse effects when taken with methylxanthines.
Sida cordifolia contains ephedrine. Use of ephedrine-containing herbs with caffeine or other methylxanthines such as theophylline might increase the risk of stimulatory adverse effects. Some clinical research and case reports suggest that using ephedrine with caffeine might increase the risk of serious life-threatening or debilitating adverse effects such as hypertension, myocardial infarction (MI), stroke, seizures, and death.

Likelihood Probable Evidence D
Qt Interval-Prolonging Drugs

Theoretically, Sida cordifolia might increase the risk of additive QT interval prolongation when taken with QT interval-prolonging drugs.
Sida cordifolia contains ephedrine. Clinical research shows that ephedrine from another herb, ephedra, can prolong the QT interval.

Likelihood Probable Evidence B
Stimulant Drugs

Theoretically, Sida cordifolia might increase the risk of adverse cardiovascular effects when taken with stimulant drugs.
Sida cordifolia contains ephedrine. Drugs with CNS stimulant properties, such as phenylpropanolamine, pseudoephedrine, and diethylpropion, and many others can increase the risk of hypertension and adverse cardiovascular effects when taken with ephedrine.

Likelihood Probable Evidence D
Antidiabetes Drugs

Theoretically, Sida cordifolia might reduce the effectiveness of antidiabetes drugs.
Sida cordifolia contains ephedrine. Clinical research shows that ephedrine can increase blood glucose levels.

Likelihood Probable Evidence B
Dexamethasone (Decadron)

Theoretically, Sida cordifolia might reduce the effectiveness of dexamethasone.
Sida cordifolia contains ephedrine. Clinical research shows that ephedrine can increase the clearance rate of dexamethasone.

Likelihood Possible Evidence B
Ergot Derivatives

Theoretically, Sida cordifolia might increase the risk of additive hypertension when taken with ergot derivatives.
Sida cordifolia contains ephedrine, which can cause vasoconstriction. This can lead to significant elevations in blood pressure when taken with ergot derivatives.

Likelihood Probable Evidence B
Monoamine Oxidase Inhibitors (Maois)

Theoretically, Sida cordifolia might increase the risk of hypertension when taken with MAOIs.
Sida cordifolia contains ephedrine. Clinical research shows that ephedrine can increase blood pressure.

Likelihood Probable Evidence B
Sida acuta full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Sida Acuta, from the product label.

Samsara Herbs

See all Samsara Herbs products
Name
Aspen Copacking
Street Address
810 North 2800 West
City
Lindon
State
Utah
ZipCode
84042
Pharmacist Counseling Corner

Sida Acuta by Samsara Herbs: Common Questions

Does Sida Acuta by Samsara Herbs interact with any medications?
Yes. Based on its ingredients, Sida Acuta has a known interaction with 445 medications, including 337 rated major. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Sida Acuta contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
No. The safety data rates Sida acuta as likely unsafe during both pregnancy and breastfeeding. Ephedrine (its active stimulant) can harm a developing baby or pass into breast milk and harm a nursing infant. Do not use this product if you are pregnant or breastfeeding.
What are the side effects I should watch for?
Nervous system effects include dizziness, restlessness, irritability, trouble concentrating, insomnia, and headache. You may also experience anxiety, personality changes, or psychosis. Most serious are cardiovascular effects: heart palpitations, abnormal heart rhythm, high blood pressure, heart attack, and stroke have been reported. Long-term use can lead to dependence.
Why does this product interact with so many medications?
Sida acuta contains ephedrine, a powerful stimulant. Ephedrine affects your heart rate, blood pressure, and how your body processes blood sugar and hormones — that's why it conflicts with heart drugs, blood pressure medication, stimulants, caffeine, diabetes drugs, and others. The interactions are not with dozens of separate substances, but with one active ingredient affecting multiple drug classes.
Is this product banned?
Ephedrine-containing products are banned in many contexts because of serious health risks. The safety notes for this product specifically mention it is banned in many products due to heart and blood pressure dangers.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Sida Acuta label
Go deeper

The Full Monographs Behind Sida Acuta’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Sida Cordifolia

Interacts with 445 drugs

Sida cordifolia (bala or country mallow) is a traditional Ayurvedic plant that naturally contains ephedrine, a powerful stimulant. Because of this, many supplements containing it have been b...

Read the full Sida Cordifolia monograph →
Sources

Sources & How We Checked

Sida Acuta's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 29 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Sida Cordifolia 29 references
  1. Okada S, Rohan PJ, Miller FW, et al. Myopathies following ingestion of special nutritional products. Arthritis Rheum 1996;39:349.
  2. Zaacks SM, Klein L, Tan CD, et al. Hypersensitivity myocarditis associated with ephedra use. J Toxicol Clin Toxicol 1999;37:485-9. PubMed
  3. Powell T, Hsu FF, Turk J, Hruska K. Ma-huang strikes again: ephedrine nephrolithiasis. Am J Kidney Dis 1998;32:153-9. PubMed
  4. Theoharides TC. Sudden death of a healthy college student related to ephedrine toxicity from a ma-huang containing drink. J Clin Psychopharmacol 1997;17:437-9. PubMed
  5. Vahedi K, Domingo V, Amarenco P, Bousser MG. Ischemic stroke in a sportsman who consumed MaHuang extract and creatine monohydrate for bodybuilding. J Neurol Neurosurg Psychiatr 2000;68:112-3.
  6. Doyle H, Kargin M. Herbal stimulant containing ephedrine has also caused psychosis. BMJ 1996;313:756. PubMed
  7. For Dieter, Nearly the Ultimate Loss. The Washington Post. Available at: http://www.washingtonpost.com/archive/politics/2000/03/19/for-dieter-nearly-the-ultimate-loss/c0f07474-489d-4f44-bc17-1f1367c956ae/ (Accessed 19 March 2000).
  8. FDA Takes Aim at Ephedra. The Washington Post. Available at: http://www.washingtonpost.com/archive/politics/2000/03/19/fda-takes-aim-at-ephedra/4ce534a7-d291-44ec-88a8-38e97ff27e3b/ (Accessed 19 March 2000).
  9. FDA. Proposed rule: dietary supplements containing ephedrine alkaloids. Available at: www.verity.fda.gov (Accessed 25 January 2000).
  10. Boozer CN, Nasser JA, Heymsfield SB, et al. An herbal supplement containing Ma Huang-Guarana for weight loss: a randomized, double-blind trial. Int J Obes Relat Metab Disord 2001;25:316-24. PubMed
  11. Anon. Sida Cordifolia. Metro Marketing, Inc. Available at: http://metromkt.net/viable/1sidacor.shtml (Accessed 9 March 2000).
  12. Gurley BJ, Gardner SF, Hubbard MA. Content versus label claims in ephedra-containing dietary supplements. Am J Health Syst Pharm 2000;57:963-9. PubMed
  13. White LM, Gardner SF, Gurley BJ, et al. Pharmacokinetics and Cardiovascular Effects of Ma-Huang (Ephedra sinica) in Normotensive Adults. J Clin Pharmacol 1997;37:116-22.
  14. Haller CA, Benowitz NL. Adverse cardiovascular and central nervous system events associated with dietary supplements containing ephedra alkaloids. N Engl J Med 2000;343:1833-8. PubMed
  15. Leikin JB, Klein L. Ephedra causes myocarditis. Clin Toxicol 2000;38:353-4.
  16. Jacobs KM, Hirsch KA. Psychiatric complications of Ma-huang. Psychosomatics 2000;41:58-62. PubMed
  17. Dulloo AG. Herbal simulation of ephedrine and caffeine in treatment of obesity. Int J Obes Relat Metab Disord 2002;26:590-2. PubMed
  18. Samenuk D, Link MS, Homoud MK, et al. Adverse cardiovascular events temporally associated with ma huang, an herbal source of ephedrine. Mayo Clin Proc 2002;77:12-6. PubMed
  19. Boozer CN, Daly PA, Homel P, et al. Herbal ephedra/caffeine for weight loss: a 6-month randomized safety and efficacy trial. Int J Obes Relat Metab Disord 2002;26:593-604. PubMed
  20. Morgenstern LB, Viscoli CM, Kernan WN, et al. Use of Ephedra-containing products and risk for hemorrhagic stroke. Neurology 2003;60:132-5. .
  21. Kalman D, Incledon T, Gaunaurd I, et al. An acute clinical trial evaluating the cardiovascular effects of an herbal ephedra-caffeine weight loss product in healthy overweight adults. Int J Obes 2002;26:1363-66.. PubMed
  22. Kockler DR, McCarthy MW, Lawson CL. Seizure activity and unresponsiveness after hydroxycut ingestion. Pharmacotherapy 2001;21:647-51.. PubMed
  23. Yates KM, O'Connor A, Horsley CA. "Herbal Ecstasy": a case series of adverse reactions. N Z Med J 2000;113:315-7..
  24. Walton R, Manos GH. Psychosis related to ephedra-containing herbal supplement use. South Med J 2003;96:718-20.. PubMed
  25. Jenkins DJ, Wesson V, Wolever TM, et al. Wholemeal versus wholegrain breads: proportion of whole or cracked grain and the glycaemic response. BMJ 1988;297:958-60. PubMed
  26. McBride BF, Karapanos AK, Krudysz A, et al. Electrocardiographic and hemodynamic effects of a multicomponent dietary supplement containing ephedra and caffeine: a randomized controlled trial. JAMA 2004;291:216-21. PubMed
  27. Brooks SM, Sholiton LJ, Werk EE Jr, Altenau P. The effects of ephedrine and theophylline on dexamethasone metabolism in bronchial asthma. J Clin Pharmacol 1977;17:308-18. PubMed
  28. Gardner SF, Franks AM, Gurley BJ, et al. Effect of a multicomponent, ephedra-containing dietary supplement (Metabolife 356) on Holter monitoring and hemostatic parameters in healthy volunteers. Am J Cardiol 2003;91:1510-3, A9. PubMed
  29. Haller CA, Jacob P 3rd, Benowitz NL. Enhanced stimulant and metabolic effects of combined ephedrine and caffeine. Clin Pharmacol Ther 2004;75:259-73.

See these in context on the Sida Cordifolia monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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