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Dietary supplement

Astaxanthins 10 mg Ingredients & Drug Interactions

by Signature Supplements

Capsule Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Astaxanthins 10 mg is a dietary supplement by Signature Supplements with 1 active ingredient. Its ingredients are commonly taken for antioxidant support, skin health and aging, eye health.Based on those ingredients, 671 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Astaxanthin. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Astaxanthins 10 mg by Signature Supplements

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: astaxanthin 10 mg per capsule. Astaxanthin is a carotenoid — a type of pigment found naturally in seafood and algae that gives them their reddish color.

It's included in this product as a standalone supplement. The capsule also contains two inactive ingredients: cellulose and diatomaceous earth, which help form and fill out the capsule.

Does it work?

Not established
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not established

The graded evidence we hold for these ingredients covers different conditions than the ones this product is marketed for, so there's no established rating for its stated use — see Astaxanthin's own graded uses on its monograph.

Why this rating?
  • The label markets this product for: Powerful antioxidant.
  • We looked for evidence on: Aging skin, Age-related macular degeneration (AMD), Dry eye, Exercise-induced muscle damage, Exercise-induced muscle soreness, Heart failure — and 4 related terms.
  • The closest evidence on file: Astaxanthin is rated "Insufficient Reliable Evidence To Rate" for Age-related macular degeneration (AMD) (Natural Medicines).
  • Also on file: Astaxanthin is rated "Insufficient Reliable Evidence To Rate" for Aging skin, Heart failure, Dry eye, Exercise-induced muscle soreness, and more.

The evidence for astaxanthin isn't well established yet. Our data shows insufficient reliable evidence to rate it for age-related cognitive decline, age-related macular degeneration (AMD), aging skin, Alzheimer disease, athletic performance, or carpal tunnel syndrome.

That doesn't mean it doesn't work — it means we don't have solid human research showing that it does. If you're considering astaxanthin for one of these conditions, talk with your doctor or pharmacist about whether the current research supports trying it.

The evidence, ingredient by ingredient Astaxanthin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Astaxanthin is generally well tolerated in studies, though long-term safety data are limited. The most common side effects are abdominal pain, diarrhea, and red-colored stool — the red color is just the pigment coming through.

At the 10 mg dose in this product, side effects are uncommon, but at much higher doses (40 mg daily) severe stomach pain has been reported in a small number of cases. There isn't enough safety data to know whether astaxanthin is safe during pregnancy or breastfeeding.

The safety data advises against use in both situations. If you're pregnant, planning to become pregnant, or breastfeeding, talk with your doctor or pharmacist before starting this supplement.

Side effects, ingredient by ingredient Astaxanthin

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Astaxanthin.
  • The most serious interaction on file is rated Moderate.
  • For scale: 672 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you start astaxanthin, check any medications you take that are broken down by the CYP3A4 liver enzyme (Moderate severity) — this includes many statins, blood pressure drugs, antihistamines, and others. Also check drugs metabolized by CYP2B6 (Moderate severity), which is a smaller group but still important.

Use the search tool on this page with your exact medication names.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no established evidence rating for its marketed use. Moderate medication interactions have been identified, and safety information is well characterized.

Astaxanthin may be worth considering if you're interested in antioxidant support and you've checked with your pharmacist about liver-enzyme interactions. If you take any medications metabolized by CYP3A4 or CYP2B6 — a very common group — verify them first.

Skip this product during pregnancy or breastfeeding. Your pharmacist can help you weigh the limited evidence and check your specific drugs.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Astaxanthins 10 mg, straight from the product label.

Brand Signature Supplements
Net contents 100 Capsule(s)
Market status On market
Date entered into DSLD Sep 25, 2025
DSLD ID 338605
Product type Non-nutrient/non-botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Astaxanthins 10 mg by Signature Supplements, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
50
IngredientAmount% DV
Astaxanthin20 mg--

Other ingredients: Cellulose, Diatomaceous Earth

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Contains no: chemical fillers or binders, artificial coloring, artificial flavor, preservatives, yeast, corn, milk or milk derivatives, lactose, salt, sodium, soy, sugar, gluten, starch or wheat.

From a GMP facility

Powerful antioxidant

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Directions: For adults, take two (2) capsules daily, more if needed.

Precautions

As a reminder, discuss the supplements and medications you take with your health care providers.

Keep out of reach of children.

Storage

Store in a dry place and avoid excessive heat.

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

See for yourself

Astaxanthins 10 mg by Signature Supplements label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Astaxanthins 10 mg by Signature Supplements

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container50 Amounts shown are per serving.

Astaxanthin

Interacts with
671 drugs
20 mg per serving Form: Marine Algae

Astaxanthin is a reddish carotenoid pigment with strong antioxidant activity in the lab, and it is widely promoted for skin, eye, heart, and exercise...

Astaxanthin monograph & interactions

Other (inactive) ingredients: Cellulose, Diatomaceous Earth. These complete the product’s ingredient list but are not active constituents.

Interaction report

Astaxanthins 10 mg by Signature Supplements Drug Interactions

Want to check YOUR meds against Astaxanthins 10 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
671Drugs
671 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Astaxanthins 10 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Astaxanthin2 drug types · 671 drugs

Cytochrome P450 2B6 (Cyp2B6) Substrates

Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP2B6.
In vitro research shows that astaxanthin induces cytochrome CYP2B6 enzyme activity in human hepatocytes. This effect has not been reported in humans.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, astaxanthin may decrease levels of drugs metabolized by CYP3A4.
In vitro research shows that astaxanthin induces CYP3A4 enzyme activity in human hepatocytes. This effect has not been reported in humans.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Astaxanthins 10 mg, from the product label.

Signature Supplements

See all Signature Supplements products
Name
Signature Supplements
Street Address
P.O. Box 1112
City
San Clemente
State
CA
Web Address
yoursignaturesupplements.com
Pharmacist Counseling Corner

Astaxanthins 10 mg by Signature Supplements: Common Questions

Does Astaxanthins 10 mg by Signature Supplements interact with any medications?
Yes. Based on its ingredients, Astaxanthins 10 mg has a known interaction with 671 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Astaxanthins 10 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What is astaxanthin and why is it in this supplement?
Astaxanthin is a natural pigment found in seafood and algae that acts as an antioxidant in your body. It's included in supplements because people are interested in its potential effects on aging and eye health, though the evidence for these uses is still limited.
Can I take this if I'm pregnant or breastfeeding?
No, there isn't enough safety data on astaxanthin during pregnancy or breastfeeding, so the data advises against use in both situations. Talk with your doctor or pharmacist before taking it if you're pregnant, planning to become pregnant, or nursing.
What side effects should I watch for?
The most common are abdominal pain, diarrhea, and red-colored stool — the red color is just the supplement's pigment and isn't harmful. Severe stomach pain has been reported only at much higher doses than this one. If you notice side effects, stop and contact your pharmacist.
Does astaxanthin actually work for aging skin or eye health?
The evidence isn't well established yet in our data. We don't have enough reliable human research to say whether it works for aging skin, age-related macular degeneration, or other conditions listed. That's why we rate those uses as having insufficient evidence.
Why do I need to check my medications before taking this?
Astaxanthin may speed up how your liver breaks down certain drugs, potentially lowering their levels and making them less effective. Many common medications depend on the CYP3A4 liver enzyme, so it's important to run your exact drugs through the checker on this page.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Astaxanthins 10 mg label
Sources

Sources & How We Checked

Astaxanthins 10 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 3 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Astaxanthin 3 references
  1. Kupcinskas L, Lafolie P, Lignell A, et al. Efficacy of the natural antioxidant astaxanthin in the treatment of functional dyspepsia in patients with or without Helicobacter pylori infection: A prospective, randomized, double blind, and placebo-controlled
  2. Kistler, A., Liechti, H., Pichard, L., Wolz, E., Oesterhelt, G., Hayes, A., and Maurel, P. Metabolism and CYP-inducer properties of astaxanthin in man and primary human hepatocytes. Arch.Toxicol. 2002;75(11-12):665-675. PubMed
  3. Choi HD, Youn YK, Shin WG. Positive effects of astaxanthin on lipid profiles and oxidative stress in overweight subjects. Plant Foods Hum Nutr. 2011;66:363-369. PubMed

See these in context on the Astaxanthin monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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