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Dietary supplement

Astragalus Root 1500 mg Ingredients & Drug Interactions

by Vitacost

Capsule Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Astragalus Root 1500 mg is a dietary supplement by Vitacost with 1 active ingredient. Its ingredients are commonly taken for immune support, colds and flu, upper respiratory infections.Based on those ingredients, 208 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Astragalus. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Astragalus Root 1500 mg by Vitacost

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: astragalus root at 1500 mg per capsule. Astragalus is a traditional herb used in Chinese medicine, and practitioners have recommended it for a range of conditions from immune support to heart health.

The capsule itself is made of gelatin, an inactive ingredient.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Astragalus product and its label doesn't state a use — see Astragalus's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for astragalus isn't well established for the conditions studied. The data we hold rates it insufficient reliable evidence for allergic rhinitis (hay fever), amenorrhea, aplastic anemia, angina, asthma, and beta-thalassemia.

That means the research so far hasn't been strong enough to say whether it works for those uses.

The evidence, ingredient by ingredient Astragalus

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Astragalus is generally well tolerated when taken short-term by healthy adults, but solid human safety data is limited. Some people in clinical trials have reported dizziness or, rarely, chest pain–like symptoms, though it's unclear whether astragalus caused them.

The safety data advises against taking it during pregnancy or while breastfeeding because there isn't enough information to know it's safe.

Side effects, ingredient by ingredient Astragalus

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Astragalus.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: immunosuppressants / transplant drugs; diabetes medications; lithium.
  • For scale: 208 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you take this product, double-check with your doctor or pharmacist if you use immunosuppressants (after transplant or for autoimmune disease), lithium, cyclophosphamide, or diabetes drugs. No interactions are documented for any other ingredient we could check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Astragalus might appeal to you if you're looking for immune support, but the evidence for specific conditions isn't strong. If you take an immunosuppressant, lithium, chemotherapy, or diabetes medication, talk with your doctor or pharmacist before starting — the interactions are real enough to matter.

Pregnant or breastfeeding folks should skip it and discuss other options with their healthcare provider.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Oct 25, 2013.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Astragalus Root 1500 mg, straight from the product label.

Brand Vitacost
Barcode (UPC) 844197017294
Net contents 100 Capsule(s)
Market status On market
Date entered into DSLD Oct 25, 2013
DSLD ID 26721
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Astragalus Root 1500 mg by Vitacost, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
3 Capsule(s)
Maximum serving Sizes:
3 Capsule(s)
Servings per container
33
UPC/BARCODE
844197017294
IngredientAmount% DV
Astragalus1500 mg--

Other ingredients: Gelatin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Herbal support for general well-being. What is astragalus? Astragalus, from the Astragalus membranaceus plant, is a herb native to China that been used for centuries as an adaptogen and restorative tonic. An adaptopgen is a substance that can help the body adapt to stress, bringing back homeostatic balance after exposure to an internal or external stimulus.

Item #: VCT 7017294 Weight: 0.2 Potency: 1500 mg

Suggested/Recommended/Usage/Directions

Vitacost Astragalus Root Directions As a dietary supplement, take 3 capsules with food daily, or as directed by a healthcare professional.

Storage

Store in a cool, dry place.

Precautions

Warnings Pregnant or lactating women, diabetics, hypoglycemics, and people with known medical conditions and/or taking drugs should consult with a licensed physician and/or pharmacist prior to taking dietary supplements.

Keep out of reach of children.

See for yourself

Astragalus Root 1500 mg by Vitacost label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Astragalus Root 1500 mg by Vitacost

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size3 Capsule(s) Dosage formCapsule Servings per container33 Amounts shown are per serving.

Astragalus

Interacts with
208 drugs
1500 mg per serving

Astragalus is a root used for centuries in traditional Chinese medicine, mainly to support the immune system and help the body cope with stress. While...

Astragalus monograph & interactions

Other (inactive) ingredients: Gelatin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Astragalus Root 1500 mg by Vitacost Drug Interactions

Want to check YOUR meds against Astragalus Root 1500 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
208Drugs
208 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Astragalus Root 1500 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Astragalus4 drug types · 208 drugs

Antidiabetes Drugs

Theoretically, taking astragalus with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research in humans shows that astragalus might have hypoglycemic effects. Theoretically, taking astragalus, especially in combination with other hypoglycemic agents, might increase the risk of hypoglycemia.

Likelihood Probable Evidence A
Cyclophosphamide

Theoretically, astragalus might interfere with cyclophosphamide therapy.
Evidence regarding the effect of astragalus on immunosuppression caused by cyclophosphamide is conflicting. Some animal research suggests that astragalus reverses cyclophosphamide-induced immunosuppression. However, other animal research shows no effect.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, astragalus might interfere with immunosuppressive therapy.
Astragalus seems to stimulate immune function. Theoretically, taking astragalus might decrease the effects of immunosuppressive therapy.

Likelihood Possible Evidence D
Lithium

Theoretically, astragalus might increase levels and adverse effects of lithium.
Animal research suggests that astragalus has diuretic properties. Theoretically, due to this diuretic effect, astragalus might reduce excretion and increase levels of lithium.

Likelihood Probable Evidence D
The maker

Brand information

Manufacturer and brand details for Astragalus Root 1500 mg, from the product label.

Vitacost

See all Vitacost products
Name
Vitacost
Pharmacist Counseling Corner

Astragalus Root 1500 mg by Vitacost: Common Questions

Does Astragalus Root 1500 mg by Vitacost interact with any medications?
Yes. Based on its ingredients, Astragalus Root 1500 mg has a known interaction with 208 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Astragalus Root 1500 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take astragalus if I'm pregnant or breastfeeding?
The safety data advises against it — there isn't enough reliable information to know it's safe during pregnancy or while breastfeeding. Talk with your doctor or pharmacist about whether this is right for you and what other options might work.
What are the side effects I might notice?
Astragalus is generally well tolerated, but some people in trials have reported dizziness. In rare cases, chest pain–like symptoms (lacunar angina) were reported, though it's unclear if astragalus was the cause. If you notice anything concerning, stop and call your pharmacist or doctor.
Does astragalus actually work for immune support?
The evidence isn't established in our data. We don't have reliable research to say whether it works for the conditions studied, including allergic rhinitis, asthma, or heart conditions. That doesn't mean it doesn't work — just that the research hasn't been strong enough yet.
Can I take this with my immunosuppressant medication?
You need to talk with your doctor or pharmacist first. Astragalus stimulates immune function, which could theoretically interfere with immunosuppressive therapy — this is a Moderate-level interaction concern.
What's in this besides astragalus?
The capsule is made of gelatin. That's the only inactive ingredient — no fillers or binders beyond that.
Is there a risk if I take astragalus and diabetes medication together?
Yes — astragalus may lower blood sugar on its own, and combining it with insulin or oral diabetes drugs could raise the risk of low blood sugar. Check with your doctor or pharmacist before taking both.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Astragalus Root 1500 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Astragalus Root 1500 mg label
Go deeper

The Full Monographs Behind Astragalus Root 1500 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Astragalus Root 1500 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 13 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Astragalus 13 references
  1. Upton R, ed. Astragalus Root: Analytical, quality control, and therapeutic monograph. Santa Cruz, CA: American Herbal Pharmacopoeia. 1999:1-25.
  2. Khoo KS, Ang PT. Extract of astragalus membranaceus and ligustrum lucidum does not prevent cyclophosphamide-induced myelosuppression. Singapore Med J 1995;36:387-90.
  3. Chu DT, Wong WL, Mavligit GM. Immunotherapy with Chinese medicinal herbs. II. Reversal of cyclophosphamide-induced immune suppression by administration of fractionated Astragalus membranaceus in vivo. J Clin Lab Immunol 1988;25:125-9.
  4. Sun Y, Hersh EM, Lee SL, et al. Preliminary observations on the effects of the Chinese medicinal herbs Astragalus membranaceus and Ligustrum lucidum on lymphocyte blastogenic responses. J Biol Response Mod 1983;2:227-37..
  5. Ma J, Peng A, Lin S. Mechanisms of the therapeutic effect of astragalus membranaceus on sodium and water retention in experimental heart failure. Chin Med J (Engl) 1998;111:17-23.
  6. Matkovic Z, Zivkovic V, Korica M, et al. Efficacy and safety of Astragalus membranaceus in the treatment of patients with seasonal allergic rhinitis. Phytother Res 2010;24:175-81.
  7. Zhang, J. G., Yang, N., He, H., Wei, G. H., Gao, D. S., Wang, X. L., Wang, X. Z., and Song, G. Y. [Effect of Astragalus injection on plasma levels of apoptosis-related factors in aged patients with chronic heart failure.]. Chin J Integr.Med 2005;11(3):18 PubMed
  8. Chen, H. W., Lin, I. H., Chen, Y. J., Chang, K. H., Wu, M. H., Su, W. H., Huang, G. C., and Lai, Y. L. A novel infusible botanically-derived drug, PG2, for cancer-related fatigue: a phase II double-blind, randomized placebo-controlled study. Clin Invest PubMed
  9. Tian H, Lu J, He H, et al.The effect of Astragalus as an adjuvant treatment in type 2 diabetes mellitus: A (preliminary) meta-analysis. J Ethnopharmacol. 2016;191:206-215. doi: 10.1016/j.jep.2016.05.062. PubMed
  10. Hong KF, Liu PY, Zhang W, Gui DK, Xu YH. The Efficacy and Safety of Astragalus as an Adjuvant Treatment for Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis. J Integr Complement Med 2023. PubMed
  11. Chan KW, Kwong ASK, Tsui PN, et al. Add-on astragalus in type 2 diabetes and chronic kidney disease: A multi-center, assessor-blind, randomized controlled trial. Phytomedicine 2024;130:155457. PubMed
  12. Han X, Yu T, Chen X, Du Z, Yu M, Xiong J. Effect of Astragalus membranaceus on left ventricular remodeling in HFrEF: a systematic review and meta-analysis. Front Pharmacol 2024;15:1345797. PubMed
  13. Jing P, Hongzheng H, Zhenqi WU, Meijuan Z, Zuojing LI, Gang C. Long-term efficacy and safety of Huangqi ()-based Traditional Chinese Medicine in diabetic peripheral neuropathy: a Meta-analysis of randomized controlled trials. J Tradit Chin Med 2024;44(2):

See these in context on the Astragalus monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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