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Dietary supplement

Beet Root 1300 mg Ingredients & Drug Interactions

by Number One Nutrition

Beet Root 1300 mg label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Beet Root 1300 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Beet Root 1300 mg is a dietary supplement by Number One Nutrition with 1 active ingredient. Its ingredients are commonly taken for high blood pressure, exercise and athletic performance, heart and circulation support.Based on those ingredients, 861 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Beetroot, Powder. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Beet Root 1300 mg by Number One Nutrition

Ask about any prescription or over-the-counter medication and we check it for interactions with Beet Root 1300 mg by Number One Nutrition — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Beet Root 1300 mg by Number One Nutrition

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Beet Root 1300 mg contains one active ingredient: beetroot powder at 1,300 mg per capsule. Beetroot is a concentrated form of the common food vegetable, supplying compounds called betanins (the red pigment) and nitrates that are believed to support exercise performance and blood flow.

The capsule also contains inactive ingredients — cellulose, microcrystalline cellulose, and magnesium stearate — which are fillers and binders that hold the supplement together.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: Concentrated beet root for energy and immunity.
  • We looked for evidence on: Athletic performance, Exercise-induced muscle damage, Exercise-induced muscle soreness, Hypertension, Pregnancy-induced hypertension, Endurance — and 3 related terms.
  • The strongest evidence on file: Beet is rated "Possibly Effective" for Athletic performance (Natural Medicines).
  • Also on file: Beet is rated "Possibly Effective" for Exercise-induced muscle soreness.
  • Also on file: Beet is rated "Insufficient Reliable Evidence To Rate" for Pregnancy-induced hypertension, Pulmonary hypertension, Exercise-induced muscle damage.

The evidence on beetroot is mixed. It's rated possibly effective for athletic performance and exercise-induced muscle soreness (the pain you feel in muscles a day or two after a hard workout).

For other uses — chronic obstructive pulmonary disease (COPD), high cholesterol levels (dyslipidemia), and brain function (cognitive function) — the evidence we hold is either insufficient to say whether it works or suggests it may not be effective. If you're considering this for athletic recovery, the data is more promising, but talk with your pharmacist about whether it fits your goals.

The evidence, ingredient by ingredient Beet

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Beetroot is widely eaten as a food and is generally well tolerated. Short-term use as a medicinal supplement also appears well tolerated in most adults.

However, concentrated supplements lack the long-term safety data that food does, so use caution if you're taking this regularly. Common side effects are harmless: red or black stools and red urine — the red color comes from the pigment and isn't dangerous.

Rare serious effects — low blood calcium (hypocalcemia) and kidney damage — have been reported only with very large amounts. One case involved a patient on blood thinners (apixaban and clopidogrel) who developed black stools after taking beet pills; the patient was evaluated and a serious bleed was ruled unlikely.

Because concentrated supplements lack full safety data, talk with your pharmacist before starting, especially if you have kidney disease or are on blood thinners.

Side effects, ingredient by ingredient Beet

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Beet.
  • The most serious interaction on file is rated Moderate.
  • For scale: 862 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Beet Root 1300 mg, double-check any medications your liver metabolizes using the CYP3A4 enzyme — this is a large group that includes many heart, immunosuppressant, and cholesterol drugs. Also mention any antihypertensive (blood pressure) medications you're on, since beet's nitrates could theoretically lower pressure further.

If you're on blood thinners (anticoagulants) or antiplatelet drugs, flag those too — one case linked beet to black stools in a patient on these drugs.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Beet Root 1300 mg may help with exercise performance and muscle soreness, and it's generally well tolerated as a food. But the interaction profile is substantial — especially with drugs your liver breaks down using the CYP3A4 enzyme — so check your medications with us before you start.

If you're on blood pressure drugs, immunosuppressants, or blood thinners, a conversation with your pharmacist is a must.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jul 24, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Beet Root 1300 mg, straight from the product label.

Brand Number One Nutrition
Barcode (UPC) X002HQ1RZD
Net contents 120 Veg Cap(s)
Market status On market
Date entered into DSLD Jul 24, 2025
DSLD ID 335943
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Beet Root 1300 mg by Number One Nutrition, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Veggie Capsule(s)
Maximum serving Sizes:
2 Veggie Capsule(s)
Servings per container
60
UPC/BARCODE
X002HQ1RZD
IngredientAmount% DV
Beetroot, Powder1300 mg--

Other ingredients: Cellulose, Microcrystalline Cellulose, Magnesium Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Concentrated beet root for energy and immunity

Suggested/Recommended/Usage/Directions

Suggested use: As a dietary supplement take two (2) capsules once a day with food or as directed by your health care professional.

Precautions

Caution: Do not exceed recommended dose.

Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.

Pregnant or nursing mothers, children under the age of 18, and individuals with a known medical condition should consult a physician before using this or any dietary supplement.

Keep out of the reach of children.

Do not use if safety seal is damaged or missing.

Formulation

No binders

With natural ingredients

Ultimate All natural Made in USA Supports performance and endurance Supports healthy blood pressure Increase energy levels naturally Cardiovascular health support

Dairy free Soy free Non-GMO Gluten free

Seals/Symbols

3rd Party Tested Guarantee Purity. Potency. Safety. Sourced from a GMP Certified Facility Made in USA Made in an FDA Registered Facility

100% Satisfaction Guarantee

General Statements

2 Please recycle

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

FDA Statement of Identity

Dietary Supplement

Storage

Store in a cool, dry place.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Beet Root 1300 mg by Number One Nutrition label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Beet Root 1300 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Beet Root 1300 mg by Number One Nutrition

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Veggie Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Beetroot, Powder

Interacts with
861 drugs
1300 mg per serving

Beet, especially beetroot juice, is a nitrate-rich food that may modestly lower blood pressure and slightly improve exercise performance in some peopl...

Beetroot, Powder monograph & interactions

Other (inactive) ingredients: Cellulose, Microcrystalline Cellulose, Magnesium Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Beet Root 1300 mg by Number One Nutrition Drug Interactions

Want to check YOUR meds against Beet Root 1300 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
861Drugs
643 Moderate 218 Minor

Ingredients driving the most interactions

Beetroot, Powder 861

Individual Drug Interactions

The ingredients in Beet Root 1300 mg interact with 861 drugs. Click any drug to see the details.

1 of the 1 ingredient in Beet Root 1300 mg interact with drugs. Each result below shows which ingredient is responsible. Beetroot, Powder

Each ingredient & the kinds of drugs it affects

For each ingredient in Beet Root 1300 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Beetroot, Powder3 drug types · 861 drugs

Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, beet might increase the levels of CYP3A4 substrates.
In vitro research suggests that betanin, the major pigment in beet, competitively inhibits CYP3A4 in a dose-dependent manner similarly to strong CYP3A4 inhibitor ketoconazole.

Likelihood Possible Evidence D
Antihypertensive Drugs

Beet and beetroot contain nitrates, which can cause vasodilation, potentially leading to lower blood pressure. However, a study published in the European Journal of Clinical Nutrition using concentrated beetroot juice found no significant impact on blood pressure or heart rate in different age groups. Other small clinical studies suggest that while beet consumption might transiently lower blood pressure due to vessel dilation, there's no consistent evidence of a lasting effect. Overall, the theoretical risk of reduced blood pressure due to beet's nitrate content exists, but studies generally indicate a low and temporary impact rather than a sustained decrease.

Likelihood Possible Evidence A
Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, beet might decrease the levels and clinical effects of CYP1A2 substrates.
In vitro research suggests that beet induces CYP1A2 enzymes.

Likelihood Possible Evidence D
Beetroot, Powder full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Beet Root 1300 mg, from the product label.

Number One Nutrition

See all Number One Nutrition products
Name
Number One Nutrition
Street Address
382 NE 191 St. #27349
City
Miami
State
FL
ZipCode
33179
Phone Number
1-786-401-4021
Web Address
www.numberonenutrition.com
Pharmacist Counseling Corner

Beet Root 1300 mg by Number One Nutrition: Common Questions

Does Beet Root 1300 mg by Number One Nutrition interact with any medications?
Yes. Based on its ingredients, Beet Root 1300 mg has a known interaction with 861 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Beet Root 1300 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this actually help me perform better during workouts?
The evidence suggests it's possibly effective for athletic performance and for exercise-induced muscle soreness. That means some research supports it, but the data isn't as strong as for prescription medications. It's worth trying if you're curious, but don't expect a dramatic change — and talk with your pharmacist first if you're on any medications.
Are the red stools and red urine dangerous?
No — the red color is just the beet pigment passing through your body and is completely harmless. You may also see black stools. These color changes are normal and expected with beet supplementation.
Is this safe to take long-term?
Beetroot as a food is safe long-term, but concentrated supplements lack that long-term safety data. Stick with short-term use, and if you're thinking of taking it regularly, check with your pharmacist first, especially if you have kidney disease.
Can I take this if I'm on blood pressure medication?
You'll need to talk with your pharmacist. Beet contains nitrates that can lower blood pressure, and combining it with blood pressure drugs creates a theoretical risk of pressure dropping too low. One study found no significant effect, but individual responses vary, so your exact medications matter here.
What's the difference between beet powder and fresh beets?
This is a concentrated powder, meaning the active compounds are more potent than fresh beets and the dose per capsule is much higher. That's why the safety data is less certain for the supplement compared to eating beets as food — you're getting a lot more, fast, rather than a small amount over time.
Does this help with high cholesterol or brain function?
The evidence we have either isn't strong enough to say it works for those uses, or suggests it may not be effective. If you're interested in beetroot for those reasons, it's worth discussing with your doctor whether it fits your plan.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Beet Root 1300 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Beet Root 1300 mg label
Go deeper

The Full Monographs Behind Beet Root 1300 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Beet

Interacts with 861 drugs

Beet, especially beetroot juice, is a nitrate-rich food that may modestly lower blood pressure and slightly improve exercise performance in some people. It is generally safe as a food, but s...

Read the full Beet monograph →
Sources

Sources & How We Checked

Beet Root 1300 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 14 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Beet 14 references
  1. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  2. Clifford T, Berntzen B, Davison GW, et al. Effects of beetroot juice on recovery of muscle function and performance between bouts of repeated sprint exercise. Nutrients 2016;8. pii: E506. PubMed
  3. Siervo M, Lara J, Ogbonmwan I, Mathers JC. Inorganic nitrate and beetroot juice supplementation reduces blood pressure in adults: a systematic review and meta-analysis. J Nutr 2013;143:818-26. PubMed
  4. Clifford T, Howatson G, West DJ, Stevenson EJ. Beetroot juice is more beneficial than sodium nitrate for attenuating muscle pain after strenuous eccentric-bias exercise. Appl Physiol Nutr Metab. 2017;42(11):1185-1191. PubMed
  5. Clifford T, Bell O, West DJ, Howatson G, Stevenson EJ. The effects of beetroot juice supplementation on indices of muscle damage following eccentric exercise. Eur J Appl Physiol. 2016;116(2):353-62. PubMed
  6. Wylie LJ, Kelly J, Bailey SJ, et al. Beetroot juice and exercise: pharmacodynamic and dose-response relationships. J Appl Physiol (1985). 2013;115(3):325-36. PubMed
  7. Garnacho-Castaño MV, Palau-Salvà G, Cuenca E, et al. Effects of a single dose of beetroot juice on cycling time trial performance at ventilatory thresholds intensity in male triathletes. J Int Soc Sports Nutr. 2018;15(1):49. PubMed
  8. Rasica L, Porcelli S, Marzorati M, et al. Ergogenic effects of beetroot juice supplementation during severe-intensity exercise in obese adolescents. Am J Physiol Regul Integr Comp Physiol. 2018;315(3):R453-R460. PubMed
  9. Henrohn D, Björkstrand K, Lundberg JO, et al. Effects of oral supplementation with nitrate-rich beetroot juice in patients with pulmonary arterial hypertension-results from BEET-PAH, an exploratory randomized, double-blind, placebo-controlled, crosso
  10. Serra-Payá N, Garnacho-Castaño MV, Sánchez-Nuño S, et al. The relationship between resistance exercise performance and ventilatory efficiency after beetroot juice intake in well-trained athletes. Nutrients 2021;13(4):1094. PubMed
  11. Haron MH, Dale O, Martin K, et al. Evaluation of the Herb-Drug Interaction Potential of Commonly Used Botanicals on the US Market with Regard to PXR- and AhR-Mediated Influences on CYP3A4 and CYP1A2. J Diet Suppl 2022. PubMed
  12. Hemmatinafar M, Zaremoayedi L, Koushkie Jahromi M, et al. Effect of Beetroot Juice Supplementation on Muscle Soreness and Performance Recovery after Exercise-Induced Muscle Damage in Female Volleyball Players. Nutrients 2023;15(17):3763. PubMed
  13. Lim SH, Bae S, Lee HS, Han HK, Choi CI. Effect of Betanin, the Major Pigment of Red Beetroot (Beta vulgaris L.), on the Activity of Recombinant Human Cytochrome P450 Enzymes. Pharmaceuticals (Basel) 2023;16(9):1224. PubMed
  14. Oscherwitz M, Tamayo RM, Heudebert A, Centor R. A Case of Pseudo-Hematochezia from Beet Supplement Ingestion. Am J Med 2023;136(9):e177-e178. PubMed

See these in context on the Beet monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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