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Dietary supplement

Potassium Iodide 130 mg Ingredients & Drug Interactions

by Number One Nutrition

Potassium Iodide 130 mg label
See full label image
Tablet Or Pill Category: Mineral
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Potassium Iodide 130 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Potassium Iodide 130 mg is a dietary supplement by Number One Nutrition with 1 active ingredient. Its ingredients are commonly taken for preventing or treating low potassium (hypokalemia), supporting healthy blood pressure, muscle cramps.Based on those ingredients, 62 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Potassium Iodide. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Potassium Iodide 130 mg by Number One Nutrition

Ask about any prescription or over-the-counter medication and we check it for interactions with Potassium Iodide 130 mg by Number One Nutrition — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Potassium Iodide 130 mg by Number One Nutrition

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: potassium iodide at 130 mg per tablet. Potassium iodide is a mineral supplement — potassium for electrolyte balance and iodine for thyroid function.

The tablet also contains several inactive ingredients used as binders and flow agents: microcrystalline cellulose, dicalcium phosphate, stearic acid, colloidal silicon dioxide, magnesium stearate, and croscarmellose sodium.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Potassium product and its label doesn't state a use — see Potassium's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The product facts we have don't include effectiveness ratings for potassium iodide, so we can't tell you from our data how well it works for its intended purpose. If you have questions about whether it's right for your specific health goal, your doctor or pharmacist can help you weigh the evidence.

The evidence, ingredient by ingredient Potassium

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Potassium is generally well tolerated when you take it by mouth. The most common side effects are digestive — abdominal pain, belching, diarrhea, gas, nausea, and vomiting.

Serious side effects from high potassium levels are rare but dangerous: they include irregular heartbeat, heart block, low blood pressure, and mental confusion. Because potassium from food is fine but supplements carry risk, the safety data advises caution.

Supplements should only be used under medical guidance, especially if you have kidney disease, are pregnant, or are breastfeeding. If you fall into any of those groups, talk with your doctor or pharmacist before starting.

Side effects, ingredient by ingredient Potassium

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Potassium.
  • The most serious interaction on file is rated Moderate.
  • For scale: 62 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you start this supplement, double-check with your pharmacist if you take any of these: potassium-sparing diuretics (water pills like spironolactone), ACE inhibitors (blood pressure drugs ending in '-pril'), or angiotensin receptor blockers (blood pressure drugs ending in '-sartan'). All three raise your risk of dangerously high potassium levels when combined with this product.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Potassium Iodide 130 mg is a straightforward mineral supplement, but it's not a casual one — potassium interacts with common blood pressure and heart medications and can build up to dangerous levels in your body, especially if your kidneys aren't working well. If you take an ACE inhibitor, ARB, or potassium-sparing diuretic, check your exact medications with the tool on this page before you buy.

Talk with your pharmacist to make sure it's right for you.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 22, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Potassium Iodide 130 mg, straight from the product label.

Brand Number One Nutrition
Barcode (UPC) X003PSI04X
Net contents 150 Tablet(s)
Market status On market
Date entered into DSLD Aug 22, 2025
DSLD ID 335997
Product type Mineral
Supplement form Tablet Or Pill
Dietary claims / uses Nutrient, All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Children (All), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Potassium Iodide 130 mg by Number One Nutrition, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tablet(s)
Maximum serving Sizes:
2 Tablet(s)
Servings per container
75
UPC/BARCODE
X003PSI04X
IngredientAmount% DV
Potassium Iodide130 mg--

Other ingredients: Microcrystalline Cellulose, Dicalcium Phosphate, Stearic Acid, Colloidal Silicon Dioxide, Magnesium Stearate, Croscarmellose Sodium

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formulation

Supports overall health + immune defense

Vegan friendly

Premium Made in USA with globally coursed ingredients

Dairy free Soy free Gluten free Gelatin free

Suggested/Recommended/Usage/Directions

Suggested use: Potassium Iodide should only be taken in emergency situations or as directed by your physician, state, or local health authorities. FDA and CDC Recommended Dosage Adults 150 lbs and above 130mg (2 tablets) Children 3+ up to 150 lbs 65mg (1 tablet)

Precautions

Suggested use: Potassium Iodide should only be taken in emergency situations or as directed by your physician, state, or local health authorities. Caution: Do not exceed suggested use. This is for short term use only. Do not take longer than 2 weeks unless directed by your physician, state or local health authorities. Do not use if safety seal is damaged or missing.

If you are pregnant, nursing, taking any medications or have thyroids or any medication condition, consult your physician before use.

Keep out of reach of children.

Short term use only

Storage

Store in a cool, dry place.

Seals/Symbols

GMP Sourced from a GMP Certified Facility FDA Formulated in a registered & inspected facility 3rd party tested Purity. Potency. Safety. Guarantee

100% Satisfaction Guarantee

General Statements

Recycle

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Formula

KI Pills

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Potassium Iodide 130 mg by Number One Nutrition label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Potassium Iodide 130 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Potassium Iodide 130 mg by Number One Nutrition

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container75 Amounts shown are per serving.

Potassium Iodide

Interacts with
62 drugs
130 mg per serving

Potassium is an essential mineral your body needs for nerve signals, muscle function, and a steady heartbeat, and most people get enough from a balanc...

Potassium Iodide monograph & interactions

Other (inactive) ingredients: Microcrystalline Cellulose, Dicalcium Phosphate, Stearic Acid, Colloidal Silicon Dioxide, Magnesium Stearate, Croscarmellose Sodium. These complete the product’s ingredient list but are not active constituents.

Interaction report

Potassium Iodide 130 mg by Number One Nutrition Drug Interactions

Want to check YOUR meds against Potassium Iodide 130 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
62Drugs
62 Moderate

Ingredients driving the most interactions

Potassium Iodide 62

Individual Drug Interactions

The ingredients in Potassium Iodide 130 mg interact with 62 drugs. Click any drug to see the details.

1 of the 1 ingredient in Potassium Iodide 130 mg interact with drugs. Each result below shows which ingredient is responsible. Potassium Iodide

Each ingredient & the kinds of drugs it affects

For each ingredient in Potassium Iodide 130 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Potassium Iodide3 drug types · 62 drugs

Ace Inhibitors (Aceis)

Using ACEIs with high doses of potassium increases the risk of hyperkalemia.
ACEIs block the actions of the renin-angiotensin-aldosterone system and reduce potassium excretion. Concomitant use of these drugs with potassium supplements increases the risk of hyperkalemia. However, concomitant use of these drugs with moderate dietary potassium intake (about 3775-5200 mg daily) does not increase serum potassium levels.

Likelihood Likely Evidence C
Angiotensin Receptor Blockers (Arbs)

Using ARBs with high doses of potassium increases the risk of hyperkalemia.
ARBs block the actions of the renin-angiotensin-aldosterone system and reduce potassium excretion. Concomitant use of these drugs with potassium supplements increases the risk of hyperkalemia. However, concomitant use of these drugs with moderate dietary potassium intake (about 3775-5200 mg daily) does not increase serum potassium levels.

Likelihood Likely Evidence C
Potassium-Sparing Diuretics

Concomitant use increases the risk of hyperkalemia.
Using potassium-sparing diuretics with potassium supplements increases the risk of hyperkalemia.

Likelihood Likely Evidence C
Potassium Iodide full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Potassium Iodide 130 mg, from the product label.

Number One Nutrition

See all Number One Nutrition products
Name
Number One Nutrition
Street Address
382 NE 191 St. #27349
City
Miami
State
FL
ZipCode
33179
Phone Number
1-786-401-4021
Web Address
www.numberonenutrition.com
Pharmacist Counseling Corner

Potassium Iodide 130 mg by Number One Nutrition: Common Questions

Does Potassium Iodide 130 mg by Number One Nutrition interact with any medications?
Yes. Based on its ingredients, Potassium Iodide 130 mg has a known interaction with 62 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Potassium Iodide 130 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is potassium iodide safe during pregnancy?
According to the safety data, potassium from food is appropriate during pregnancy, but supplements should only be used under medical guidance. If you're pregnant or thinking about getting pregnant, talk with your doctor before taking this supplement.
Can I take this while breastfeeding?
Dietary potassium is fine, but the data advises checking with your doctor before using supplements while breastfeeding. Your doctor can advise you based on your individual situation.
What's the difference between potassium from food and potassium supplements?
Potassium from a normal diet is safe and necessary. Supplements, on the other hand, can cause dangerously high blood potassium levels in some people, especially those with kidney disease. That's why supplements need medical guidance.
What are the most common side effects?
Taking potassium by mouth usually causes digestive upset — things like abdominal pain, gas, diarrhea, nausea, or vomiting. These are generally mild, but if they're bothersome or don't go away, let your pharmacist know.
What happens if potassium gets too high in my body?
High potassium can cause an irregular heartbeat, heart block, a sudden drop in blood pressure, or confusion. These are serious but rare — which is why it's so important to check your medications before starting this supplement and only use it under medical guidance.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Potassium Iodide 130 mg is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Potassium Iodide 130 mg label
Go deeper

The Full Monographs Behind Potassium Iodide 130 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Potassium

Interacts with 62 drugs

Potassium is an essential mineral your body needs for nerve signals, muscle function, and a steady heartbeat, and most people get enough from a balanced diet rich in fruits and vegetables. P...

Read the full Potassium monograph →
Sources

Sources & How We Checked

Potassium Iodide 130 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 12 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Potassium 12 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Gennaro A. Remington: The Science and Practice of Pharmacy. 19th ed. Lippincott: Williams & Wilkins, 1996.
  3. Whelton PK, He J, Cutler JA, et al. Effects of oral potassium on blood pressure. Meta-analysis of randomized controlled clinical trials. JAMA 1997;277:1624-32. PubMed
  4. Phillips, C. O., Kashani, A., Ko, D. K., Francis, G., and Krumholz, H. M. Adverse effects of combination angiotensin II receptor blockers plus angiotensin-converting enzyme inhibitors for left ventricular dysfunction: a quantitative review of data from ra DOI
  5. Altieri, P. I., Herrero, C., Suero, R., and Ortiz, A. Bleeding duodenal ulcer in a patient taking slow-releasing potassium tablets. Bol.Asoc.Med P.R. 1977;69(8):276.
  6. Raf, L. E. Enteric-coated potassium chloride tablets and ulcer of the small intestine. Acta Chir Scand Suppl 1967;(374):1-87.
  7. Potassium chloride oral solution [package insert]. Allentown, PA: Lehigh Valley Technologies, Inc.; 2014.
  8. Potassium chloride injection [package insert]. Lake Forest, IL: Hospira Inc.; 2009.
  9. Patel RB, Tannenbaum S, Viana-Tejedor A, et al. Serum potassium levels, cardiac arrhythmias, and mortality following non-ST-elevation myocardial infarction or unstable angina: insights from MERLIN-TIMI 36. Eur Heart J Acute Cardiovasc Care 2017 Feb;6(1):1 PubMed
  10. Malta D, Arcand J, Ravindran A, Floras V, Allard JP, Newton GE. Adequate intake of potassium does not cause hyperkalemia in hypertensive individuals taking medications that antagonize the renin angiotensin aldosterone system. Am J Clin Nutr 2016 Oct;104(4 PubMed
  11. Keskin M, Kaya A, Tatlisu MA, et al. The effect of serum potassium level on in-hospital and long-term mortality in ST elevation myocardial infarction. Int J cardiol. 2016 Oct 15;221:505-10.
  12. Stallings VA, Harrison M, Oria M; Committee to Review the Dietary Reference Intakes for Sodium and Potassium, Food and Nutrition Board, Health and Medicine Division, National Academies of Sciences, Engineering, and Medicine. Washington (DC): National Acad

See these in context on the Potassium monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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