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Dietary supplement

Benfotiamine 150 mg Ingredients & Drug Interactions

by BIOVEA

Benfotiamine 150 mg label
See full label image
Capsule Category: Vitamin
Most serious interaction: Minor
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Benfotiamine 150 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Minor

Benfotiamine 150 mg is a dietary supplement by BIOVEA with 2 active ingredients. Its ingredients are commonly taken for preventing or treating thiamine deficiency, beriberi, wernicke-korsakoff syndrome (alcohol-related).Based on those ingredients, 3 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are Thiamine. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Benfotiamine 150 mg by BIOVEA

Ask about any prescription or over-the-counter medication and we check it for interactions with Benfotiamine 150 mg by BIOVEA — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Benfotiamine 150 mg by BIOVEA

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 16, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

This supplement has 2 active ingredients: thiamine and benfotiamine. Thiamine is a B vitamin your body needs to convert food into energy and support nerve and heart function.

Benfotiamine is a fat-soluble form of thiamine that some research suggests may be easier for your body to absorb and use, especially in the nerves. The capsule also contains inactive ingredients (fillers and binders): hydroxypropyl methylcellulose, microcrystalline cellulose, vegetable magnesium stearate, and silicon dioxide.

Does it work?

Strong evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded its ingredients' overall clinical evidence instead.

Strong

Strong clinical evidence supports its ingredients for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredients' overall clinical evidence instead.
  • On file: Thiamine deficiency — rated "Effective" (Thiamine) (Natural Medicines).
  • On file: Wernicke-Korsakoff syndrome (WKS) — rated "Effective" (Thiamine) (Natural Medicines).
  • On file: Dysmenorrhea — rated "Possibly Effective" (Thiamine) (Natural Medicines).
  • On file: Diabetic neuropathy — rated "Possibly Effective" (Benfotiamine) (Natural Medicines).

Thiamine is effective for treating thiamine deficiency and Wernicke-Korsakoff syndrome (a serious brain condition caused by severe thiamine lack). It's possibly effective for period pain (dysmenorrhea), but possibly ineffective for heart failure.

The evidence doesn't support it as a mosquito repellent. Benfotiamine is possibly effective for diabetic nerve damage (diabetic neuropathy).

For other uses listed — diabetic kidney disease, alcohol use disorder, Alzheimer disease, and general peripheral nerve damage — the evidence we hold is insufficient to say whether it works.

The evidence, ingredient by ingredient Thiamine Benfotiamine

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 2 of 2.
  • General safety write-ups exist for 2 of 2.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Thiamine is generally very well tolerated by mouth at normal doses. Allergic skin reactions and other allergic reactions are rare.

Thiamine is needed in pregnancy and while breastfeeding, and the safety rating is Likely Safe — but use only the amounts your doctor advises. Benfotiamine is generally well tolerated in the studies we have, but long-term safety hasn't been fully studied.

In one trial of 98 people taking 300–600 mg daily for 6 weeks, a small number reported allergic skin reactions and slight stomach discomfort, at rates no different from placebo. We don't have enough data on benfotiamine safety during pregnancy or breastfeeding, so check with your doctor or pharmacist before taking it if you're pregnant or nursing.

Side effects, ingredient by ingredient Thiamine Benfotiamine

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 2 matched ingredients can interact with medications — Thiamine.
  • The most serious interaction on file is rated Minor.
  • For scale: 3 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check whether you're on trimethoprim (Proloprim), an antibiotic that can raise thiamine blood levels. Because benfotiamine hasn't been fully studied for long-term safety and pregnancy/breastfeeding, mention this supplement to your doctor or pharmacist if you're pregnant, nursing, or planning to be.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with strong clinical evidence behind its ingredients' uses. Only minor medication interactions are documented, and safety information is well characterized.

This product may be worth considering if you have a thiamine deficiency, Wernicke-Korsakoff syndrome, or diabetic nerve damage — though for the latter, the evidence is still developing. If you take trimethoprim or any other prescription medications, check them against the search tool on this page before you start.

Talk it over with your doctor or pharmacist to make sure it fits your situation.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Dec 22, 2019.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Benfotiamine 150 mg, straight from the product label.

Brand BIOVEA
Barcode (UPC) 818423021003
Net contents 60 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Dec 22, 2019
DSLD ID 209289
Product type Vitamin
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Benfotiamine 150 mg by BIOVEA, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Vegetarian Capsule(s)
Maximum serving Sizes:
1 Vegetarian Capsule(s)
Servings per container
60
UPC/BARCODE
818423021003
IngredientAmount% DV
Thiamine103 mg8583%
Benfotiamine150 mg--

Other ingredients: Hydroxypropyl Methylcellulose, Microcrystalline Cellulose, Vegetable Magnesium Stearate, Silicon Dioxide

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Seals/Symbols

GMP Compliant VG Vegan Gluten free

Formulation

VG Vegan

Gluten free

General Statements

Premium quality guaranteed since 2001. BIOVEA is committed to product quality to support you and your family's wellness goals. Because we feel so strongly about the quality, potency and purity our products, we 100% guarantee your satisfaction with every purchase.

Guaranteed premium quality

Fat soluble form of B-1

Suggested/Recommended/Usage/Directions

Suggested Daily Intake: Take 1 capsule up to 4 times a day with meals.

Precautions

Warning: If you are pregnant or lactating, consult a healthcare professional before using this product.

Keep out of reach of children.

Do not use this product if the safety seal on the bottle is broken.

Storage

Store in a cool, dry place.

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Benfotiamine 150 mg by BIOVEA label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Benfotiamine 150 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Benfotiamine 150 mg by BIOVEA

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Vegetarian Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Thiamine

Interacts with
3 drugs
103 mg per serving Form: Thiamine Mononitrate

Thiamine (vitamin B1) is an essential nutrient your body needs to turn food into energy and to keep your nerves and heart healthy. Most people get eno...

Thiamine monograph & interactions

Benfotiamine

No known
interactions
150 mg per serving

Benfotiamine is a man-made, fat-soluble form of vitamin B1 (thiamine) that the body may absorb more easily than regular thiamine. It is mostly studied...

Benfotiamine monograph & interactions

Other (inactive) ingredients: Hydroxypropyl Methylcellulose, Microcrystalline Cellulose, Vegetable Magnesium Stearate, Silicon Dioxide. These complete the product’s ingredient list but are not active constituents.

Interaction report

Benfotiamine 150 mg by BIOVEA Drug Interactions

Want to check YOUR meds against Benfotiamine 150 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
3Drugs
3 Minor

Ingredients driving the most interactions

Thiamine 3

Individual Drug Interactions

The ingredients in Benfotiamine 150 mg interact with 3 drugs. Click any drug to see the details.

1 of the 2 ingredients in Benfotiamine 150 mg interact with drugs. Each result below shows which ingredient is responsible. Thiamine

Each ingredient & the kinds of drugs it affects

For each ingredient in Benfotiamine 150 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Thiamine1 drug type · 3 drugs

Trimethoprim (Proloprim)

Trimethoprim might increase blood levels of thiamine.
In vitro, animal, and clinical research suggest that trimethoprim inhibits intestinal thiamine transporter ThTR-2, hepatic transporter OCT1, and renal transporters OCT2, MATE1, and MATE2, resulting in paradoxically increased thiamine plasma concentrations.

Likelihood Probable Evidence B
Thiamine full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Benfotiamine 150 mg, from the product label.

BIOVEA

See all BIOVEA products
Name
BIOVEA
Street Address
9160 E. Bahia Dr.
City
Scottsdale
State
AZ
ZipCode
85260
Web Address
www.biovea.com
Pharmacist Counseling Corner

Benfotiamine 150 mg by BIOVEA: Common Questions

Does Benfotiamine 150 mg by BIOVEA interact with any medications?
Yes. Based on its ingredients, Benfotiamine 150 mg has a known interaction with 3 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Benfotiamine 150 mg contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is thiamine safe to take while I'm pregnant or breastfeeding?
Thiamine is rated Likely Safe in pregnancy and lactation — in fact, you need it during both. Use only the dose your doctor or pharmacist recommends. For benfotiamine, we don't have enough safety data during pregnancy or breastfeeding, so check with your healthcare provider before taking this product if you're pregnant or nursing.
What is benfotiamine, and how is it different from regular thiamine?
Benfotiamine is a fat-soluble form of thiamine (a B vitamin). Because it dissolves in fat rather than water, some research suggests your body may absorb and use it more readily, especially in nerve tissue. This product gives you both forms.
Does this product help with diabetic nerve pain?
Benfotiamine is possibly effective for diabetic nerve damage (diabetic neuropathy). The evidence is still developing, so talk with your doctor about whether it makes sense for you alongside your other treatments.
What side effects might I notice?
Both ingredients are generally well tolerated. Allergic skin reactions are rare with thiamine. In trials of benfotiamine, a small number of people reported allergic skin reactions or mild stomach discomfort, but these occurred at the same rate as placebo.
I take trimethoprim for an infection. Can I use this supplement?
Trimethoprim can raise thiamine blood levels by slowing how your body clears it. This is a Minor interaction, but mention this supplement to your doctor or pharmacist so they can monitor you if needed.
How much thiamine am I actually getting from this 150 mg capsule?
The product label says 150 mg, but we don't have a breakdown of how much comes from thiamine alone versus benfotiamine alone. Check the label or contact the manufacturer for that detail.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Benfotiamine 150 mg is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Benfotiamine 150 mg label
Go deeper

The Full Monographs Behind Benfotiamine 150 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Thiamine

Interacts with 3 drugs

Thiamine (vitamin B1) is an essential nutrient your body needs to turn food into energy and to keep your nerves and heart healthy. Most people get enough from food, but supplements are clear...

Read the full Thiamine monograph → Herb & supplement monograph

Benfotiamine

Benfotiamine is a man-made, fat-soluble form of vitamin B1 (thiamine) that the body may absorb more easily than regular thiamine. It is mostly studied for diabetic nerve problems, but the ev...

Read the full Benfotiamine monograph →
Sources

Sources & How We Checked

Benfotiamine 150 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 8 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Thiamine 7 references
  1. McEvoy GK, ed. AHFS Drug Information. Bethesda, MD: American Society of Health-System Pharmacists, 1998.
  2. Yates AA, Schlicker SA, Suitor CW. Dietary reference intakes: The new basis for recommendations for calcium and related nutrients, B vitamins, and choline. J Am Diet Assoc 1998;98:699-706. PubMed
  3. Food and Nutrition Board, Institute of Medicine. Dietary Reference Intakes for Thiamin, Riboflavin, Niacin, Vitamin B6, Folate, Vitamin B12, Pantothenic Acid, Biotin, and Choline (2000). Washington, DC: National Academy Press, 2000. Available at: http://b
  4. Rogovik, A. L., Vohra, S., and Goldman, R. D. Safety considerations and potential interactions of vitamins: should vitamins be considered drugs? Ann.Pharmacother. 2010;44(2):311-324. PubMed
  5. Arruti N, Bernedo N, Audicana MT, Villarreal O, Uriel O, Muñoz D. Systemic allergic dermatitis caused by thiamine after iontophoresis. Contact Dermatitis. 2013 Dec;69(6):375-6. PubMed
  6. Thiamine hydrochloride injection package insert. Lake Zurich, IL: Fresenius Kabi, LLC; September 2019.
  7. Vora B, Wen A, Yee SW, et al. The Effect of Trimethoprim on Thiamine Absorption: A Transporter-Mediated Drug-Nutrient Interaction. Clin Pharmacol Ther 2023;114(2):381-392.

See these in context on the Thiamine monograph →

Benfotiamine 1 reference
  1. Stracke H, Gaus W, Achenbach U, Federlin K, Bretzel RG. Benfotiamine in diabetic polyneuropathy (BENDIP): results of a randomised, double blind, placebo-controlled clinical study. Exp Clin Endocrinol Diabetes 2008;116(10):600-5. PubMed

See these in context on the Benfotiamine monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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