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Dietary supplement

BergaCor Ingredients & Drug Interactions

by XYMOGEN

Tablet Or Pill Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

BergaCor is a dietary supplement by XYMOGEN with 1 active ingredient. Its ingredients are commonly taken for high cholesterol, heart and metabolic health, anxiety and stress (aromatherapy).Based on those ingredients, 410 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Bergamot Polyphenolic Fraction Gold. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of BergaCor by XYMOGEN

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

BergaCor contains one active ingredient: bergamot polyphenolic fraction gold, a concentrated extract from bergamot fruit. The tablet also contains several inactive ingredients — croscarmellose sodium, microcrystalline cellulose, ascorbyl palmitate, silica, hydroxypropyl methylcellulose, and medium chain triglyceride — that serve as binders and fillers to hold the tablet together.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: cardiovascular and metabolic health support.
  • We looked for evidence on: Hyperlipidemia, Metabolic syndrome, Impaired glucose tolerance (prediabetes), Nonalcoholic fatty liver disease (NAFLD), Obesity, dyslipidemia — and 1 related terms.
  • The strongest evidence on file: Bergamot is rated "Possibly Effective" for Hyperlipidemia (Natural Medicines).
  • Also on file: Bergamot is rated "Insufficient Reliable Evidence To Rate" for Nonalcoholic fatty liver disease (NAFLD), Obesity, Impaired glucose tolerance (prediabetes), Metabolic syndrome.

Bergamot has possibly effective evidence for high cholesterol (hyperlipidemia). For mental alertness, the evidence leans possibly ineffective.

For nonalcoholic fatty liver disease and autism spectrum disorder, there isn't enough reliable evidence in the data we hold to rate its effectiveness either way.

The evidence, ingredient by ingredient Bergamot

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

The oral extract in BergaCor appears generally well tolerated when used short-term, though one person in clinical research reported heartburn. The bergamot essential oil itself can be toxic if swallowed and may cause sun-related skin reactions, so this product's form and dose matter.

The safety data advises against bergamot during pregnancy and breastfeeding — there isn't enough information to know it's safe in either situation, so talk with your doctor or pharmacist if you're pregnant, planning pregnancy, or nursing before taking this product.

Side effects, ingredient by ingredient Bergamot

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Bergamot.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 410 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking BergaCor, double-check with your doctor or pharmacist if you take photosensitizing drugs (Moderate severity) or antidiabetes medications (Moderate severity). Bergamot can theoretically raise the risk of sun sensitivity with the first group and low blood sugar with the second.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

BergaCor may be worth considering if you have high cholesterol and want to explore natural support, but it's not the right fit if you take diabetes medications or drugs that increase sun sensitivity without checking first. The oral extract is generally tolerated short-term, though pregnancy and breastfeeding are reasons to skip it.

Talk with your own doctor or pharmacist before starting, especially if you're on any prescription medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Dec 14, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about BergaCor, straight from the product label.

Brand XYMOGEN
Barcode (UPC) 871149007287
Net contents 60 Tablet(s)
Market status On market
Date entered into DSLD Dec 14, 2023
DSLD ID 303647
Product type Botanical
Supplement form Tablet Or Pill
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for BergaCor by XYMOGEN, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Tablet(s)
Maximum serving Sizes:
2 Tablet(s)
Servings per container
30
UPC/BARCODE
871149007287
IngredientAmount% DV
Bergamot Polyphenolic Fraction Gold1.3 Gram(s)--

Other ingredients: Croscarmellose Sodium, Microcrystalline Cellulose, Ascorbyl Palmitate, Silica, Hydroxypropyl Methylcellulose, Medium Chain Triglyceride

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

DIRECTIONS: Take one to two tablets twice daily, or as directed by your healthcare professional.

Precautions

Consult your healthcare professional before use.

Individuals taking medication should discuss potential interactions with their healthcare professional.

Do not use if tamper seal is damaged.

STORAGE: Keep closed in a cool, dry place out of reach of children.

Formula

BergaCor features a highly concentrated source of polyphenolic antioxidants derived from bergamot (Citrus bergamia), a flavonoid-rich fruit originating from the Calabria region in southern Italy and traditionally used to support cardiovascular wellness. Research has suggested that Bergamot Polyphenolic Fraction Gold (BPFG) is utilized hepatically to help maintain healthy cholesterol levels already within normal range and to support healthy blood glucose metabolism.

Cardiovascular and Blood Sugar Support from Bergamot and Amla

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Storage

STORAGE: Keep closed in a cool, dry place out of reach of children.

Formulation

FORMULATED TO EXCLUDE: Wheat, gluten, corn, yeast, soy, animal and dairy products, fish, shellfish, peanuts, tree nuts, egg, ingredients derived from genetically modified organisms (GMOs), artificial colors, artificial sweeteners, and artificial preservatives.

Brand IP Statement(s)

S1. Bergamot Polyphenolic Fraction Gold (BPFG) is a registered trademark of H&AD S.R.L.

Copyright 2020 XYMOGEN

XYMOGEN Exclusive Professional Formulas

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

ePV (ePedigree Verification)

GMP compliant third-party verified

General Statements

Scan to learn more! This package is completely recyclable

See for yourself

BergaCor by XYMOGEN label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in BergaCor by XYMOGEN

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container30 Amounts shown are per serving.

Bergamot Polyphenolic Fraction Gold

Interacts with
410 drugs
1.3 Gram(s) per serving Form: Bergamot Fruit Juice Extract

Bergamot is a Mediterranean citrus fruit, and its standardized extract is most often used to support cholesterol and heart health, with some early but...

Bergamot Polyphenolic Fraction Gold monograph & interactions

Other (inactive) ingredients: Croscarmellose Sodium, Microcrystalline Cellulose, Ascorbyl Palmitate, Silica, Hydroxypropyl Methylcellulose, Medium Chain Triglyceride. These complete the product’s ingredient list but are not active constituents.

Interaction report

BergaCor by XYMOGEN Drug Interactions

Want to check YOUR meds against BergaCor?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
410Drugs
410 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in BergaCor with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Bergamot Polyphenolic Fraction Gold2 drug types · 410 drugs

Antidiabetes Drugs

Theoretically, taking bergamot with antidiabetes drugs might increase the risk of hypoglycemia.
Animal research suggests that bergamot juice has hypoglycemic effects.

Likelihood Possible Evidence D
Photosensitizing Drugs

Theoretically, topical bergamot essential oil might increase the risk of side effects when used along with photosensitizing drugs.
Bergamot contains bergapten, which has photosensitizing effects.

Likelihood Probable Evidence D
The maker

Brand information

Manufacturer and brand details for BergaCor, from the product label.

XYMOGEN

See all XYMOGEN products
Name
XYMOGEN Exclusive Professional Formulas
Street Address
6900 Kingspointe Pkwy.
City
Orlando
State
FL
ZipCode
32819
Phone Number
800-647-6100
Web Address
www.xymogen.com
Pharmacist Counseling Corner

BergaCor by XYMOGEN: Common Questions

Does BergaCor by XYMOGEN interact with any medications?
Yes. Based on its ingredients, BergaCor has a known interaction with 410 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
BergaCor contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take BergaCor if I'm pregnant or breastfeeding?
The safety data advises against bergamot during pregnancy and while breastfeeding — there isn't enough information to know it's safe in either situation. Talk with your doctor or pharmacist before taking it if you're pregnant, planning pregnancy, or nursing.
What is bergamot polyphenolic fraction, and what's it for?
Bergamot polyphenolic fraction is a concentrated extract from bergamot fruit. The evidence suggests it may help with high cholesterol, though it hasn't been proven to improve mental alertness.
Will BergaCor make my skin more sensitive to the sun?
Bergamot contains bergapten, which has photosensitizing effects. If you take drugs that increase sun sensitivity, bergamot could theoretically add to that risk. Even topically, bergamot can cause blisters, redness, and pigment spots in some people, especially those with fair skin.
What side effects might I get from taking BergaCor orally?
The oral extract is generally well tolerated short-term. One person in a clinical study reported heartburn, but serious side effects are uncommon when taken by mouth — unlike the essential oil, which can be toxic if swallowed.
Could BergaCor cause low blood sugar?
Animal research suggests bergamot lowers blood sugar. If you take diabetes medications, combining BergaCor with them might raise your risk of low blood sugar (hypoglycemia), so check with your doctor or pharmacist first.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if BergaCor is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

BergaCor label
Sources

Sources & How We Checked

BergaCor's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 17 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Bergamot 17 references
  1. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  2. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  3. Naganuma M, Hirose S, Nakayama Y, et al. A study of the phototoxicity of lemon oil. Arch Dermatol Res 1985;278:31-6. . PubMed
  4. Kaddu, S., Kerl, H., and Wolf, P. Accidental bullous phototoxic reactions to bergamot aromatherapy oil. J.Am.Acad.Dermatol. 2001;45(3):458-461. PubMed
  5. Finsterer, J. Earl Grey tea intoxication. Lancet 4-27-2002;359(9316):1484. PubMed
  6. Gruson, L. M. and Chang, M. W. Berloque dermatitis mimicking child abuse. Arch.Pediatr.Adolesc.Med. 2002;156(11):1091-1093. PubMed
  7. Weisenseel, P. and Woitalla, S. [Toxic mustard plaster dematitis and phototoxic dematitis after application of bergamot oil]. MMW.Fortschr.Med. 12-15-2005;147(51-52):53, 55.
  8. Placzek, M., Fromel, W., Eberlein, B., Gilbertz, K. P., and Przybilla, B. Evaluation of phototoxic properties of fragrances. Acta Derm.Venereol. 2007;87(4):312-316. PubMed
  9. Mollace, V., Sacco, I., Janda, E., Malara, C., Ventrice, D., Colica, C., Visalli, V., Muscoli, S., Ragusa, S., Muscoli, C., Rotiroti, D., and Romeo, F. Hypolipemic and hypoglycaemic activity of bergamot polyphenols: from animal models to human studies. F PubMed
  10. Morliere, P., Huppe, G., Averbeck, D., Young, A. R., Santus, R., and Dubertret, L. In vitro photostability and photosensitizing properties of bergamot oil. Effects of a cinnamate sunscreen. J.Photochem.Photobiol.B 1990;7(2-4):199-208. PubMed
  11. Young, A. R., Walker, S. L., Kinley, J. S., Plastow, S. R., Averbeck, D., Morliere, P., and Dubertret, L. Phototumorigenesis studies of 5-methoxypsoralen in bergamot oil: evaluation and modification of risk of human use in an albino mouse skin model. J.P PubMed
  12. Girard, J., Unkovic, J., Delahayes, J., and Lafille, C. [Phototoxicity of Bergamot oil. Comparison between humans and guinea pigs]. Dermatologica 1979;158(4):229-243.
  13. Zaynoun, S. T., Johnson, B. E., and Frain-Bell, W. A study of oil of bergamot and its importance as a phototoxic agent. II. Factors which affect the phototoxic reaction induced by bergamot oil and psoralen derivatives. Contact Dermatitis 1977;3(5):225-23 PubMed
  14. Zacher, K. D. and Ippen, H. [Contact dermatitis caused by bergamot oil]. Derm.Beruf.Umwelt. 1984;32(3):95-97.
  15. Yasui, Y. and Hirone, T. Action spectrum for bergamot-oil phototoxicity measured by sunburn cell counting. J.Dermatol. 1994;21(5):319-322. PubMed
  16. Zaynoun, S. T., Johnson, B. E., and Frain-Bell, W. A study of oil of bergamot and its importance as a phototoxic agent. I. Characterization and quantification of the photoactive component. Br.J.Dermatol. 1977;96(5):475-482. PubMed
  17. Bruno A, Pandolfo G, Crucitti M, Cedro C, Zoccali RA, Muscatello MRA. Bergamot Polyphenolic Fraction Supplementation Improves Cognitive Functioning in Schizophrenia: Data From an 8-Week, Open-Label Pilot Study. J Clin Psychopharmacol 2017;37(4):468-71. PubMed

See these in context on the Bergamot monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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