Interactions on record — worth a quick check against your medications. Based on 7 of 9 ingredients. Check your meds →
Dietary supplement

Birth-Prep Six Week Formula Ingredients & Drug Interactions

by Christopher's Original Formulas

Birth-Prep Six Week Formula label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Birth-Prep Six Week Formula against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Birth-Prep Six Week Formula is a dietary supplement by Christopher's Original Formulas with 9 active ingredients. Its ingredients are commonly taken for cough and sore throat, dry mouth and throat irritation, digestive upset and heartburn.Based on those ingredients, 2,166 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Marshmallow, False Unicorn, Black Cohosh. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Birth-Prep Six Week Formula by Christopher's Original Formulas

Ask about any prescription or over-the-counter medication and we check it for interactions with Birth-Prep Six Week Formula by Christopher's Original Formulas — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Birth-Prep Six Week Formula by Christopher's Original Formulas

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 11, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 9 active ingredients.
  • “Proprietary Blend” is a proprietary blend — the label gives one combined amount (840 mg) without saying how much of each component you get.

Birth-Prep Six Week Formula contains nine ingredients, seven of which are herbal extracts or powders: marshmallow root and leaf (for their soothing mucilage), lobelia, black cohosh, false unicorn root, blessed thistle, red raspberry leaf, pennyroyal extract, and squaw vine powder and extract. The capsules themselves are made from plant-derived material.

There are no inactive fillers listed beyond the capsule material itself.

Does it work?

Insufficient evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Insufficient

There isn't enough reliable clinical evidence to rate this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: pregnancy and labor support during last 6 weeks.
  • We looked for evidence on: Labor pain, Parturition, Pregnancy-induced nausea and vomiting, Uterine toning, Childbirth preparation, Birth support.
  • The closest evidence on file: Red Raspberry is rated "Insufficient Reliable Evidence To Rate" for Pregnancy-induced nausea and vomiting (Natural Medicines).
  • Also on file: Red Raspberry is rated "Insufficient Reliable Evidence To Rate" for Labor pain, Parturition.
  • Also on file: Black Cohosh is rated "Insufficient Reliable Evidence To Rate" for Parturition.

The evidence supporting these ingredients is sparse. Black cohosh has been rated possibly effective for menopausal symptoms, but the other ingredients—marshmallow, lobelia, false unicorn, blessed thistle, red raspberry leaf, and pennyroyal—all lack reliable evidence to support claims about the conditions listed in our data.

We hold no effectiveness ratings for squaw vine. In short, the data we have do not establish that this formula works for its intended purpose.

The evidence, ingredient by ingredient Marshmallow Lobelia Black Cohosh False Unicorn Blessed Thistle Red Raspberry Pennyroyal

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 6 of the 7 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 7 of 7.
  • General safety write-ups exist for 7 of 7.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Several ingredients in this formula carry serious safety concerns. Pennyroyal is highly toxic—its essential oil has caused liver failure and death, and it should never be used in pregnancy or while breastfeeding.

Lobelia can be toxic at higher doses and cause nausea, vomiting, diarrhea, tremors, and at severe doses, seizures, dangerously low heart rate, and death; it is unsafe in pregnancy and lactation. Black cohosh is generally well tolerated for short-term use, but rare cases of liver damage have been reported, and it should be avoided in pregnancy and lactation.

Marshmallow, false unicorn, and blessed thistle are poorly studied in humans—marshmallow and blessed thistle should be avoided in pregnancy, and false unicorn is considered likely unsafe in pregnancy. Red raspberry leaf is often used late in pregnancy, but its safety is not well established; talk with your provider before use.

Blessed thistle is traditionally used to support milk supply, but safety has not been well studied. We could not find safety data on squaw vine.

Side effects, ingredient by ingredient Marshmallow Lobelia Black Cohosh False Unicorn Blessed Thistle Red Raspberry Pennyroyal

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 7 of the 7 matched ingredients can interact with medications — Blessed Thistle, False Unicorn, Lobelia, Red Raspberry, Pennyroyal, among others.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications; lithium.
  • For scale: 2,167 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take lithium, do not start this product without talking to your prescriber—marshmallow, lobelia, and false unicorn may raise lithium levels to toxic ranges. Similarly, check with your doctor before combining this with acetaminophen, particularly because of pennyroyal.

Also flag anticoagulants or antiplatelet drugs (red raspberry leaf may increase bleeding), insulin (red raspberry leaf may lower blood sugar), drugs that your liver processes as CYP2D6 or CYP3A4 substrates (black cohosh and false unicorn), serotonergic antidepressants (black cohosh), estrogen therapy, cisplatin, or acid-blocking medications (blessed thistle).

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with insufficient evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This is a specialized prenatal formula, and because it contains pennyroyal (highly toxic) and lobelia (which can cause serious effects), we'd strongly recommend talking with your obstetrician or midwife before starting it. If you take any prescription medications—especially lithium, heart medications, antidepressants, blood thinners, insulin, acid blockers, or acetaminophen—check them against this product with the tool below before taking your first dose.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 7 of 9 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 25, 2019.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Birth-Prep Six Week Formula, straight from the product label.

Brand Christopher's Original Formulas
Barcode (UPC) 084783891277
Net contents 100 Vegetarian Cap(s)
Market status On market
Date entered into DSLD Feb 25, 2019
DSLD ID 199885
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Pregnant Women
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Birth-Prep Six Week Formula by Christopher's Original Formulas, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Pregnant and Lactating
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
50
UPC/BARCODE
084783891277
IngredientAmount% DV
Marshmallow0 NP--
Proprietary Blend840 mg--
Lobelia0 NP--
Black Cohosh0 NP--
False Unicorn0 NP--
Blessed Thistle0 NP--
Red Raspberry0 NP--
Squaw Vine powder0 NP--
Pennyroyal 4:1 extract powder0 NP--
Squaw Vine 4:1 extract powder0 NP--

Other ingredients: plant-derived Capsule

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Recommend Dosage: This product is only to be used under a Professional Health Care Provider during the last 6 weeks of pregnancy. Take 1 capsule daily for the 1st week, 2 capsules daily during the 2nd week, and 2 capsules 3 times a day for the 3rd week and thereafter, or as directed by your health care professional. 6 capsules daily is the maximum dosage suggested.

Precautions

Recommend Dosage: This product is only to be used under a Professional Health Care Provider during the last 6 weeks of pregnancy.

Warning: Do not use during pregnancy unless supervised by a Professional Health Care Provider.

Brand IP Statement(s)

2010 Wholistic Botanicals L.L.C All Rights Reserved

John R. Christopher

FDA Statement of Identity

Dietary Supplement

General Statements

425 mg each

Formulation

No Fillers or Chemicals.

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Birth-Prep Six Week Formula by Christopher's Original Formulas label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Birth-Prep Six Week Formula label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Birth-Prep Six Week Formula by Christopher's Original Formulas

These are the 9 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container50 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Blend

840 mg per serving

Other (inactive) ingredients: Plant-derived Capsule. These complete the product’s ingredient list but are not active constituents.

Interaction report

Birth-Prep Six Week Formula by Christopher's Original Formulas Drug Interactions

Want to check YOUR meds against Birth-Prep Six Week Formula?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
2,166Drugs
1,084 Moderate 1,082 Minor

Ingredients driving the most interactions

Marshmallow 2,040
False Unicorn 740
Black Cohosh 652
Red Raspberry 135
Pennyroyal 4:1 extract powder 69

Individual Drug Interactions

The ingredients in Birth-Prep Six Week Formula interact with 2,166 drugs. Click any drug to see the details.

7 of the 9 ingredients in Birth-Prep Six Week Formula interact with drugs. Each result below shows which ingredient is responsible. Marshmallow False Unicorn Black Cohosh Red Raspberry Pennyroyal 4:1 extract powder Blessed Thistle Lobelia

Each ingredient & the kinds of drugs it affects

For each ingredient in Birth-Prep Six Week Formula with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Marshmallow3 drug types · 2,040 drugs

Lithium

Theoretically, due to potential diuretic effects, marshmallow might reduce excretion and increase levels of lithium.
Marshmallow is thought to have diuretic properties. To avoid lithium toxicity, the dose of lithium might need to be decreased when used with marshmallow.

Likelihood Probable Evidence D
Anticoagulant/Antiplatelet Drugs

Theoretically, marshmallow flower might have antiplatelet effects.
Animal research suggests that marshmallow flower extract has antiplatelet effects. However, the root and leaf of marshmallow, not the flower, are the plant parts most commonly found in dietary supplements. Theoretically, use of marshmallow flower with anticoagulant/antiplatelet drugs can have additive effects, and might increase the risk for bleeding in some patients.

Likelihood Unlikely Evidence D
Oral Drugs

Theoretically, mucilage in marshmallow might impair absorption of oral drugs.
Marshmallow contains mucilage which can affect oral drug absorption. To avoid changes in absorption, take marshmallow 30-60 minutes after oral medications.

Likelihood Possible Evidence D
Marshmallow full monograph & interactions

False Unicorn3 drug types · 740 drugs

Cytochrome P450 2D6 (Cyp2D6) Substrates

In vitro, false unicorn extract inhibits cytochrome P450 2D6 (CYP2D6) activity. Theoretically, false unicorn might increase the levels of CYP2D6 substrates. Some of drugs that are CYP2D6 substrates include amitriptyline (Elavil), clozapine (Clozaril), codeine, desipramine (Norpramin), donepezil (Aricept), fentanyl (Duragesic), flecainide (Tambocor), fluoxetine (Prozac), meperidine (Demerol), methadone (Dolophine), metoprolol (Lopressor, Toprol XL), olanzapine (Zyprexa), ondansetron (Zofran), tramadol (Ultram), trazodone (Desyrel), and others.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

In vitro, false unicorn extract inhibits cytochrome P450 3A4 (CYP3A4) activity. Theoretically, false unicorn might increase the levels of CYP3A4 substrates. Drugs that might be affected include some calcium channel blockers (diltiazem, nicardipine, verapamil), chemotherapeutic agents (etoposide, paclitaxel, vinblastine, vincristine, vindesine), antifungals (ketoconazole, itraconazole), glucocorticoids, cisapride (Propulsid), alfentanil (Alfenta), fentanyl (Sublimaze), losartan (Cozaar), fluoxetine (Prozac), midazolam (Versed), omeprazole (Prilosec), ondansetron (Zofran), propranolol (Inderal), fexofenadine (Allegra), and numerous others.

Likelihood Possible Evidence D
Lithium

False unicorn is thought to have diuretic properties. Theoretically, due to these potential diuretic effects, false unicorn might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.

Likelihood Probable Evidence D
False Unicorn full monograph & interactions

Black Cohosh7 drug types · 652 drugs

Atorvastatin (Lipitor)

Taking black cohosh with atorvastatin might increase the risk for elevated liver function tests.
In one case report, a patient taking atorvastatin (Lipitor) developed significantly elevated liver function enzymes after starting black cohosh 100 mg four times daily. Liver enzymes returned to normal when black cohosh was discontinued. It is unclear whether the elevated liver enzymes were due to black cohosh itself or an interaction between atorvastatin and black cohosh.

Likelihood Possible Evidence D
Cisplatin (Platinol-Aq)

Theoretically, black cohosh may reduce the clinical effects of cisplatin.
Animal research suggests that black cohosh might decrease the cytotoxic effect of cisplatin on breast cancer cells.

Likelihood Possible Evidence D
Cytochrome P450 2D6 (Cyp2D6) Substrates

Some research suggests that black cohosh might inhibit CYP2D6, but there is conflicting evidence.
Some clinical research suggests that black cohosh might modestly inhibit CYP2D6 and increase levels of drugs metabolized by this enzyme. However, contradictory clinical research shows a specific black cohosh product (Remifemin, Enzymatic Therapy) 40 mg twice daily does not significantly inhibit metabolism of a CYP2D6 substrate in healthy study volunteers. Until more is known, use black cohosh cautiously in patients taking drugs metabolized by CYP2D6.

Likelihood Possible Evidence B
Estrogens

Theoretically, black cohosh may alter the effects of estrogen therapy.
Some research suggests that black cohosh has estrogenic effects. This may enhance or inhibit the effects of estrogen therapy.

Likelihood Possible Evidence D
Hepatotoxic Drugs

Theoretically, taking black cohosh with hepatotoxic drugs may increase the risk of liver damage.
There is concern that black cohosh might be linked to cases of liver failure and autoimmune hepatitis.

Likelihood Possible Evidence D
Serotonergic Drugs

Combining serotonergic drugs with black cohosh might cause additive serotonergic effects.
Black cohosh might increase the risk of serotonin syndrome when combined with other serotonergic drugs. Black cohosh acts as an agonist at several serotonin receptor subtypes and might interact with other serotonergic medications. In one case, a 55-year-old female who had been on stable treatment with sertraline 50 mg and duloxetine 60 mg daily developed serotonin syndrome after taking black cohosh extract 40 mg daily for 3 days.

Likelihood Possible Evidence D
Organic Anion-Transporting Polypeptide Substrates (Oatp)

Black cohosh may inhibit one form of OATP, OATP2B1, which could reduce the bioavailability and clinical effects of OATP2B1 substrates.
In vitro research shows that black cohosh modestly inhibits OATP2B1. OATPs are expressed in the small intestine and liver and are responsible for the uptake of drugs and other compounds into the body. Inhibition of OATP may reduce the bioavailability of oral drugs that are substrates of OATP.

Likelihood Possible Evidence D
Black Cohosh full monograph & interactions

Red Raspberry2 drug types · 135 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, taking red raspberry leaf with anticoagulant/antiplatelet drugs might increase the risk of bleeding.
In vitro research suggests that red raspberry leaf extract has antiplatelet activity and enhances the in vitro effects of the antiplatelet medication cangrelor. This interaction has not been reported in humans.

Likelihood Possible Evidence D
Insulin

Red raspberry leaf might reduce glucose levels in patients being treated with insulin.
In one case report, a 38-year-old patient with gestational diabetes, whose blood glucose was being controlled with medical nutrition therapy and insulin, developed hypoglycemia after consuming two servings of raspberry leaf tea daily for 3 days beginning at 32 weeks' gestation. The patient required an insulin dose reduction. The hypoglycemia was considered to be probably related to use of red raspberry leaf tea.

Likelihood Possible Evidence D
Red Raspberry full monograph & interactions

Pennyroyal 4:1 extract powder1 drug type · 69 drugs

Acetaminophen (Tylenol, Others)

Concomitant use of pennyroyal essential oil and acetaminophen might increase the risk of acetaminophen-induced hepatotoxicity.
Pennyroyal is hepatotoxic and depletes hepatic glutathione levels in a similar manner to acetaminophen. A case report describes hepatic failure in a female who took pennyroyal and acetaminophen concurrently.

Likelihood Possible Evidence D
Pennyroyal 4:1 extract powder full monograph & interactions

Blessed Thistle3 drug types · 36 drugs

Antacids

Theoretically, blessed thistle might decrease the effectiveness of antacids.
There are reports that blessed thistle increases stomach acid.

Likelihood Possible Evidence D
H2-Blockers

Theoretically, blessed thistle might decrease the effectiveness of H2-blockers.
There are reports that blessed thistle increases stomach acid.

Likelihood Possible Evidence D
Proton Pump Inhibitors (Ppis)

Theoretically, blessed thistle might decrease the effectiveness of PPIs.
There are reports that blessed thistle increases stomach acid.

Likelihood Possible Evidence D
Blessed Thistle full monograph & interactions

Lobelia1 drug type · 1 drug

Lithium

Lobelia is thought to have diuretic properties. Theoretically, due to these potential diuretic effects, lobelia might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.

Likelihood Probable Evidence D
Lobelia full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Birth-Prep Six Week Formula, from the product label.

Christopher's Original Formulas

See all Christopher's Original Formulas products
Name
Wholistic Botanicals L.L.C.
City
Spanish Fork
State
UT
ZipCode
84660
Phone Number
1-800-453-1406
Web Address
www.drchristopher.com
Pharmacist Counseling Corner

Birth-Prep Six Week Formula by Christopher's Original Formulas: Common Questions

Does Birth-Prep Six Week Formula by Christopher's Original Formulas interact with any medications?
Yes. Based on its ingredients, Birth-Prep Six Week Formula has a known interaction with 2,166 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Birth-Prep Six Week Formula contains 9 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this while pregnant?
The safety data advise against several ingredients in pregnancy—marshmallow, false unicorn, blessed thistle, and pennyroyal should be avoided. Black cohosh is rated possibly unsafe, and red raspberry leaf's safety is not well established despite traditional use late in pregnancy. Talk with your obstetrician or midwife before starting this formula, as it's designed for pregnancy but contains ingredients the data flag as risky.
Can I take this while breastfeeding?
Marshmallow, lobelia, black cohosh, false unicorn, and pennyroyal should all be avoided while breastfeeding. Blessed thistle is traditionally used to support milk supply, but safety has not been well studied—check with your doctor first. Red raspberry leaf's safety while breastfeeding is unknown.
What does pennyroyal do in this formula?
According to our data, pennyroyal is listed for gallbladder disease, gout, insect repellent, common cold, pneumonia, and canker sores, but the evidence for any of these is insufficient. What matters is that pennyroyal essential oil is highly toxic and has caused liver failure and death—using an extract in a supplement does not make it safe, especially near pregnancy.
Does lobelia actually help with smoking cessation?
No—our data rate lobelia as possibly ineffective for smoking cessation. Beyond that, lobelia is toxic and can cause nausea, vomiting, diarrhea, tremors, and at higher doses, seizures and death. The adverse effects have been reported at doses as low as 50 mg.
What side effects might I experience?
Black cohosh commonly causes breast tenderness, dizziness, headache, and gastrointestinal upset. Lobelia can cause nausea, vomiting, diarrhea, throat irritation, and dizziness. Blessed thistle at high doses can cause stomach irritation and vomiting. Red raspberry leaf may cause diarrhea or stomach upset. Pennyroyal leaf tea is associated with dizziness, nausea, and abdominal cramping, though pennyroyal essential oil causes far more severe effects.
Is this formula safe to use long-term?
The data indicate limited human safety for most of these ingredients when used long-term. Marshmallow and black cohosh are noted as generally well tolerated for short-term use, but longer-term safety is unclear. Given the known toxicity of pennyroyal and lobelia, this formula is not suitable for extended use without medical supervision.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Birth-Prep Six Week Formula label
Go deeper

The Full Monographs Behind Birth-Prep Six Week Formula’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Marshmallow

Interacts with 2,040 drugs

Marshmallow root is a traditional herb rich in soothing, gel-like fibers called mucilage, which is why it has long been used for coughs, sore throats, and stomach irritation. Evidence for th...

Read the full Marshmallow monograph → Herb & supplement monograph

Lobelia

Interacts with 1 drug

Lobelia is a traditional herb once used for breathing problems and to help people quit smoking, but reliable evidence supporting these uses is lacking. It can be toxic in higher amounts, cau...

Read the full Lobelia monograph → Herb & supplement monograph

Black Cohosh

Interacts with 652 drugs

Black cohosh is a North American plant most often used to ease menopause symptoms like hot flashes, but the research is mixed and far from settled. It is generally well tolerated for short-t...

Read the full Black Cohosh monograph → Herb & supplement monograph

False Unicorn

Interacts with 740 drugs

False Unicorn is a North American plant whose root has long been used in traditional medicine for women's reproductive and menstrual concerns. There is very little reliable human research to...

Read the full False Unicorn monograph → Herb & supplement monograph

Blessed Thistle

Interacts with 36 drugs

Blessed thistle is a bitter herb traditionally used to stimulate appetite and ease mild digestive complaints. High-quality human studies are lacking, so its benefits are not well proven. It...

Read the full Blessed Thistle monograph → Herb & supplement monograph

Red Raspberry

Interacts with 135 drugs

Red raspberry leaf is a traditional herbal remedy most often used as a tea in late pregnancy and for menstrual discomfort, but solid scientific evidence for these uses is limited. It is gene...

Read the full Red Raspberry monograph → Herb & supplement monograph

Pennyroyal

Interacts with 69 drugs

Pennyroyal is a mint-family plant whose essential oil is highly toxic and has caused serious poisonings and deaths, especially when used to try to bring on a period or end a pregnancy. There...

Read the full Pennyroyal monograph →
Sources

Sources & How We Checked

Birth-Prep Six Week Formula's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 101 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Marshmallow 5 references
  1. Monographs on the medicinal uses of plant drugs. Exeter, UK: European Scientific Co-op Phytother, 1997.
  2. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
  3. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  4. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  5. Hage-Sleiman R, Mroueh M, Daher CF. Pharmacological evaluation of aqueous extract of Althaea officinalis flower grown in Lebanon. Pharm Biol 2011;49(3):327-33.

See these in context on the Marshmallow monograph →

Lobelia 6 references
  1. Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
  2. Leung AY, Foster S. Encyclopedia of Common Natural Ingredients Used in Food, Drugs and Cosmetics. 2nd ed. New York, NY: John Wiley & Sons, 1996.
  3. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  4. McChargue DE, Collins FL Jr, Cohen LM. Effect of non-nicotinic moist snuff replacement and lobeline on withdrawal symptoms during 48-h smokeless tobacco deprivation. Nicotine Tob Res 2002;4:195-200. PubMed
  5. Stead LF, Hughes JR. Lobeline for smoking cessation. Cochrane Database Syst Rev 2000;2:CD000124. PubMed
  6. Plakun, A. L., Ambrus, J., Bross, I., Graham, S., Levin, M. L., and Ross, C. A. Clinical factors in smoking withdrawal: preliminary report. Am J Public Health Nations.Health 1966;56(3):434-441. PubMed

See these in context on the Lobelia monograph →

Black Cohosh 68 references
  1. McFarlin BL, Gibson MH, O'Rear J, Harman P. A national survey of herbal preparation use by nurse-midwives for labor stimulation. Review of the literature and recommendations for practice. J Nurse Midwifery 1999;44:205-16. PubMed
  2. Whiting PW, Clouston A, Kerlin P. Black cohosh and other herbal remedies associated with acute hepatitis. Med J Aust 2002;177:440-3. PubMed
  3. Pepping J. Black cohosh: Cimicifuga racemosa. Am J Health Syst Pharm 1999;56:1400-2. PubMed
  4. Liske E. Therapeutic efficacy and safety of Cimicifuga racemosa for gynecologic disorders. Adv Ther 1998;15:45-53.
  5. Kruse SO, Lohning A, Pauli GF, et al. Fukiic and piscidic acid esters from the rhizome of Cimicifuga racemosa and the in vitro estrogenic activity of fukinolic acid. Planta Med 1999;65:763-4.
  6. Jacobson JS, Troxel AB, Evans J, et al. Randomized trial of black cohosh for the treatment of hot flashes among women with a history of breast cancer. J Clin Oncol 2001;19:2739-45. PubMed
  7. Gunn TR, Wright IM. The use of black and blue cohosh in labour. N Z Med J 1996;109:410-1.
  8. Baillie N, Rasmussen P. Black and blue cohosh in labour. N Z Med J 1997;110:20-1.
  9. Lontos S, Jones RM, Angus PW, Gow PJ. Acute liver failure associated with the use of herbal preparations containing black cohosh. Med J Aust 2003;179:390-1.. DOI
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False Unicorn 4 references
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Blessed Thistle 2 references
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See these in context on the Blessed Thistle monograph →

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Pennyroyal 8 references
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See these in context on the Pennyroyal monograph →

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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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