Black Chokeberry 450 mg Ingredients & Drug Interactions
by TerraVita Premium Collection
What is this page for?
First and foremost: checking Black Chokeberry 450 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Black Chokeberry 450 mg is a dietary supplement by TerraVita Premium Collection with 1 active ingredient. Its ingredients are commonly taken for antioxidant support, heart and blood vessel health, blood pressure support.Based on those ingredients, 811 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Black Chokeberry. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Black Chokeberry 450 mg by TerraVita Premium Collection
Ask about any prescription or over-the-counter medication and we check it for interactions with Black Chokeberry 450 mg by TerraVita Premium Collection — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Black Chokeberry 450 mg by TerraVita Premium Collection
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: black chokeberry extract at 450 mg per capsule. The remaining ingredients are gelatin and water, which make up the capsule itself.
Does it work?
Couldn't assess
The evidence for black chokeberry is limited. For heart disease prevention, the data suggests it is possibly ineffective.
For age-related vision loss (macular degeneration), cognitive decline with aging, athletic performance, and cancer, there isn't enough reliable evidence yet to rate whether it works.
How safe is it?
Well-documented data
Black chokeberry is generally well tolerated when eaten as food, but safety data for concentrated supplements like this capsule is sparse. Gastrointestinal side effects — constipation, diarrhea, nausea, stomach cramps, and vomiting — show up in clinical studies.
In one small trial, around 14% of people drinking chokeberry juice daily reported constipation or diarrhea; in another, about 53% reported diarrhea, nausea, stomach upset, or vomiting over 6 weeks. We have no safety data on file for use during lactation.
Meds to double-check
Moderate interaction found
Check with your pharmacist before taking this if you're on trabectedin (a cancer drug), blood thinners or antiplatelet drugs like warfarin or aspirin, diabetes medications, or any drug metabolized by the CYP3A4 enzyme in your liver — a large group that includes many statins, blood pressure drugs, and immunosuppressants.
The bottom line
Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Black chokeberry may be worth considering if you're interested in antioxidant support, but the evidence for preventing heart disease or other conditions is weak. Be cautious if you take blood thinners, diabetes drugs, or trabectedin — and know that digestive upset is fairly common.
Talk to your pharmacist before starting, especially if you're on any prescription medication.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Mar 22, 2023.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Black Chokeberry 450 mg, straight from the product label.
| Brand | TerraVita Premium Collection |
|---|---|
| Barcode (UPC) | 064435197346 |
| Net contents | 100 Capsule(s) |
| Market status | On market |
| Date entered into DSLD | Mar 22, 2023 |
| DSLD ID | 288452 |
| Product type | Botanical |
| Supplement form | Capsule |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Black Chokeberry 450 mg by TerraVita Premium Collection, sourced from the NIH Dietary Supplement Label Database.
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity
A Dietary Supplement
Brand IP Statement(s)
Copyright 2017 TerraVita - Distributed by ZooScape LLC, All Rights Reserved.
Suggested/Recommended/Usage/Directions
Directions Take 1 capsule, 3 times daily, with meals.
General Statements
TerraVita is an exclusive line of premium natural products that use the finest, purest and most potent ingredients in the world. TerraVita's hallmarks are the highest possible standards of purity, potency, stability and freshness. All products are prepared with the greatest quality control, from raw materials through the entire manufacturing process, right up to the moment your product is sealed for freshness and shipped to you.
Please recycle!
FDA Disclaimer Statement
Statements not evaluated by FDA. Product not intended to diagnose, treat, cure, or prevent any disease.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Black Chokeberry 450 mg by TerraVita Premium Collection label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Black Chokeberry 450 mg by TerraVita Premium Collection
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Capsule(s) Dosage formCapsule Servings per container100 Amounts shown are per serving.
Black Chokeberry
Interacts with811 drugs
Chokeberry (aronia) is a dark berry rich in antioxidants called polyphenols, and it's widely eaten as juice, jam, and supplements. Early research hint...
Black Chokeberry monograph & interactionsOther (inactive) ingredients: Gelatin, Water. These complete the product’s ingredient list but are not active constituents.
Black Chokeberry 450 mg by TerraVita Premium Collection Drug Interactions
HelloPharmacist Interaction Report
Black Chokeberry 450 mg by TerraVita Premium Collection does interact with certain medications.
The most serious concern is trabectedin (Yondelis), a cancer drug — chokeberry may slow how your body clears it, raising levels and side effects. One patient drinking chokeberry juice while on trabectedin developed a serious muscle breakdown condition.
If you take trabectedin, do not use this product without checking with your doctor or pharmacist first.
Read the full breakdown — every affected drug type, severity by severity
Chokeberry may also interact with blood thinners and antiplatelet drugs (like warfarin or aspirin) by increasing bleeding risk, and with diabetes medications by raising the risk of low blood sugar (hypoglycemia). Additionally, chokeberry can inhibit an enzyme (CYP3A4) in your liver that breaks down many common drugs — meaning their levels in your bloodstream could climb.
Altogether, these interactions span 800 individual medications. Please use the medication checker on this page to verify your exact prescriptions before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Black Chokeberry 450 mg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Black Chokeberry 450 mg interact with 811 drugs. Click any drug to see the details.
1 of the 1 ingredient in Black Chokeberry 450 mg interact with drugs. Each result below shows which ingredient is responsible. Black Chokeberry
Ado-trastuzumab EmtansineKadcyla
How Ado-trastuzumab Emtansine interacts with Black Chokeberry 450 mg — through 1 ingredient. Tap an ingredient for the detail:
Black ChokeberryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, chokeberry might increase levels of drugs metabolized by CYP3A4.
Read the full Black Chokeberry + Ado-trastuzumab Emtansine interactionAbciximabReoPro
How Abciximab interacts with Black Chokeberry 450 mg — through 1 ingredient. Tap an ingredient for the detail:
Black ChokeberryAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, chokeberry might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Black Chokeberry + Abciximab interactionAbemaciclibVerzenio
How Abemaciclib interacts with Black Chokeberry 450 mg — through 1 ingredient. Tap an ingredient for the detail:
Black ChokeberryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, chokeberry might increase levels of drugs metabolized by CYP3A4.
Read the full Black Chokeberry + Abemaciclib interactionAbiraterone
How Abiraterone interacts with Black Chokeberry 450 mg — through 1 ingredient. Tap an ingredient for the detail:
Black ChokeberryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, chokeberry might increase levels of drugs metabolized by CYP3A4.
Read the full Black Chokeberry + Abiraterone interactionAbiraterone AcetateYonsa, Zytiga
How Abiraterone Acetate interacts with Black Chokeberry 450 mg — through 1 ingredient. Tap an ingredient for the detail:
Black ChokeberryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, chokeberry might increase levels of drugs metabolized by CYP3A4.
Read the full Black Chokeberry + Abiraterone Acetate interactionAbrocitinibCibinqo
How Abrocitinib interacts with Black Chokeberry 450 mg — through 1 ingredient. Tap an ingredient for the detail:
Black ChokeberryAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, chokeberry might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Black Chokeberry + Abrocitinib interactionAcalabrutinibCalquence
How Acalabrutinib interacts with Black Chokeberry 450 mg — through 1 ingredient. Tap an ingredient for the detail:
Black ChokeberryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, chokeberry might increase levels of drugs metabolized by CYP3A4.
Read the full Black Chokeberry + Acalabrutinib interactionAcarboseGlucobay, Prandase, Precose
How Acarbose interacts with Black Chokeberry 450 mg — through 1 ingredient. Tap an ingredient for the detail:
Black ChokeberryAntidiabetes Drugs Moderate
Interaction Summary
Theoretically, chokeberry might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Read the full Black Chokeberry + Acarbose interactionAcenocoumarolSintrom
How Acenocoumarol interacts with Black Chokeberry 450 mg — through 1 ingredient. Tap an ingredient for the detail:
Black ChokeberryAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, chokeberry might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Black Chokeberry + Acenocoumarol interactionAcetaminophen, AspirinGemnisyn
How Acetaminophen, Aspirin interacts with Black Chokeberry 450 mg — through 1 ingredient. Tap an ingredient for the detail:
Black ChokeberryAnticoagulant/antiplatelet Drugs Moderate
Interaction Summary
Theoretically, chokeberry might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Black Chokeberry + Acetaminophen, Aspirin interactionAcetaminophen, Aspirin, CaffeineExcedrin, Excedrin Extra Strength, Excedrin Migraine
How Acetaminophen, Aspirin, Caffeine interacts with Black Chokeberry 450 mg — through 1 ingredient. Tap an ingredient for the detail:
Black ChokeberryAnticoagulant/antiplatelet Drugs, Cytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, chokeberry might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Read the full Black Chokeberry + Acetaminophen, Aspirin, Caffeine interactionAcetaminophen, Butalbital, CaffeineEsgic, Esgic Plus, Fiogesic, Fioricet, Repan, Tecnal +1 more
How Acetaminophen, Butalbital, Caffeine interacts with Black Chokeberry 450 mg — through 1 ingredient. Tap an ingredient for the detail:
Black ChokeberryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, chokeberry might increase levels of drugs metabolized by CYP3A4.
Read the full Black Chokeberry + Acetaminophen, Butalbital, Caffeine interactionAcetaminophen, Butalbital, Caffeine, CodeineEsgic with Codeine, Fioricet w/ Codeine
How Acetaminophen, Butalbital, Caffeine, Codeine interacts with Black Chokeberry 450 mg — through 1 ingredient. Tap an ingredient for the detail:
Black ChokeberryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, chokeberry might increase levels of drugs metabolized by CYP3A4.
Read the full Black Chokeberry + Acetaminophen, Butalbital, Caffeine, Codeine interactionAcetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, PhenylephrineHycomine Compound
How Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interacts with Black Chokeberry 450 mg — through 1 ingredient. Tap an ingredient for the detail:
Black ChokeberryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, chokeberry might increase levels of drugs metabolized by CYP3A4.
Read the full Black Chokeberry + Acetaminophen, Caffeine, Chlorpheniramine, Hydrocodone, Phenylephrine interactionAcetaminophen, Caffeine, CodeineGesic C15, Gesic C30, Gesic C8, Lenoltec 1, Lenoltec 2, Lenoltec 3 +1 more
How Acetaminophen, Caffeine, Codeine interacts with Black Chokeberry 450 mg — through 1 ingredient. Tap an ingredient for the detail:
Black ChokeberryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, chokeberry might increase levels of drugs metabolized by CYP3A4.
Read the full Black Chokeberry + Acetaminophen, Caffeine, Codeine interactionAcetaminophen, Caffeine, Codeine, SalicylamideCodalan No.1, Codalan No.2, Codalan No.3
How Acetaminophen, Caffeine, Codeine, Salicylamide interacts with Black Chokeberry 450 mg — through 1 ingredient. Tap an ingredient for the detail:
Black ChokeberryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, chokeberry might increase levels of drugs metabolized by CYP3A4.
Read the full Black Chokeberry + Acetaminophen, Caffeine, Codeine, Salicylamide interactionAcetaminophen, Caffeine, DihydrocodeineDHC Plus, Panlor DC, Panlor SS
How Acetaminophen, Caffeine, Dihydrocodeine interacts with Black Chokeberry 450 mg — through 1 ingredient. Tap an ingredient for the detail:
Black ChokeberryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, chokeberry might increase levels of drugs metabolized by CYP3A4.
Read the full Black Chokeberry + Acetaminophen, Caffeine, Dihydrocodeine interactionAcetaminophen, Caffeine, IsomethepteneMigralam
How Acetaminophen, Caffeine, Isometheptene interacts with Black Chokeberry 450 mg — through 1 ingredient. Tap an ingredient for the detail:
Black ChokeberryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, chokeberry might increase levels of drugs metabolized by CYP3A4.
Read the full Black Chokeberry + Acetaminophen, Caffeine, Isometheptene interactionAcetaminophen, Caffeine, PyrilamineMidol Max Strength Menstrual
How Acetaminophen, Caffeine, Pyrilamine interacts with Black Chokeberry 450 mg — through 1 ingredient. Tap an ingredient for the detail:
Black ChokeberryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, chokeberry might increase levels of drugs metabolized by CYP3A4.
Read the full Black Chokeberry + Acetaminophen, Caffeine, Pyrilamine interactionAcetaminophen, Chlorpheniramine Maleate, Dextromethorphan HbrVicks Formula 44M Cough, Cold & Flu Relief
How Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interacts with Black Chokeberry 450 mg — through 1 ingredient. Tap an ingredient for the detail:
Black ChokeberryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, chokeberry might increase levels of drugs metabolized by CYP3A4.
Read the full Black Chokeberry + Acetaminophen, Chlorpheniramine Maleate, Dextromethorphan Hbr interactionAcetaminophen, Chlorpheniramine, Codeine, PhenylephrineColrex
How Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interacts with Black Chokeberry 450 mg — through 1 ingredient. Tap an ingredient for the detail:
Black ChokeberryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, chokeberry might increase levels of drugs metabolized by CYP3A4.
Read the full Black Chokeberry + Acetaminophen, Chlorpheniramine, Codeine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, DextromethorphanCoricidin II Extra Strength Cold and Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan interacts with Black Chokeberry 450 mg — through 1 ingredient. Tap an ingredient for the detail:
Black ChokeberryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, chokeberry might increase levels of drugs metabolized by CYP3A4.
Read the full Black Chokeberry + Acetaminophen, Chlorpheniramine, Dextromethorphan interactionAcetaminophen, Chlorpheniramine, Dextromethorphan HydrobromideCoricidin HBP Maximum Strength Flu
How Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interacts with Black Chokeberry 450 mg — through 1 ingredient. Tap an ingredient for the detail:
Black ChokeberryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, chokeberry might increase levels of drugs metabolized by CYP3A4.
Read the full Black Chokeberry + Acetaminophen, Chlorpheniramine, Dextromethorphan Hydrobromide interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PhenylpropanolamineMulti Symptom Cold Relief
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interacts with Black Chokeberry 450 mg — through 1 ingredient. Tap an ingredient for the detail:
Black ChokeberryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, chokeberry might increase levels of drugs metabolized by CYP3A4.
Read the full Black Chokeberry + Acetaminophen, Chlorpheniramine, Dextromethorphan, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Dextromethorphan, PseudoephedrineChildren's Tylenol Cold Plus Cough, Tylenol Cold Ex Strength
How Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interacts with Black Chokeberry 450 mg — through 1 ingredient. Tap an ingredient for the detail:
Black ChokeberryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, chokeberry might increase levels of drugs metabolized by CYP3A4.
Read the full Black Chokeberry + Acetaminophen, Chlorpheniramine, Dextromethorphan, Pseudoephedrine interactionAcetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, SalicylamideRhinogesic GG
How Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interacts with Black Chokeberry 450 mg — through 1 ingredient. Tap an ingredient for the detail:
Black ChokeberryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, chokeberry might increase levels of drugs metabolized by CYP3A4.
Read the full Black Chokeberry + Acetaminophen, Chlorpheniramine, Guaifenesin, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylephrineAlka-Seltzer PLUS, Histex SR, Protid
How Acetaminophen, Chlorpheniramine, Phenylephrine interacts with Black Chokeberry 450 mg — through 1 ingredient. Tap an ingredient for the detail:
Black ChokeberryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, chokeberry might increase levels of drugs metabolized by CYP3A4.
Read the full Black Chokeberry + Acetaminophen, Chlorpheniramine, Phenylephrine interactionAcetaminophen, Chlorpheniramine, Phenylephrine, SalicylamideRhinogesic, Rhinogesic JR
How Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interacts with Black Chokeberry 450 mg — through 1 ingredient. Tap an ingredient for the detail:
Black ChokeberryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, chokeberry might increase levels of drugs metabolized by CYP3A4.
Read the full Black Chokeberry + Acetaminophen, Chlorpheniramine, Phenylephrine, Salicylamide interactionAcetaminophen, Chlorpheniramine, PhenylpropanolamineAlumadrine, Conex, Sinadrin Max Strength, Sinulin
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine interacts with Black Chokeberry 450 mg — through 1 ingredient. Tap an ingredient for the detail:
Black ChokeberryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, chokeberry might increase levels of drugs metabolized by CYP3A4.
Read the full Black Chokeberry + Acetaminophen, Chlorpheniramine, Phenylpropanolamine interactionAcetaminophen, Chlorpheniramine, Phenylpropanolamine, OpiumHista-Derfule
How Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interacts with Black Chokeberry 450 mg — through 1 ingredient. Tap an ingredient for the detail:
Black ChokeberryCytochrome P450 3a4 (cyp3a4) Substrates Moderate
Interaction Summary
Theoretically, chokeberry might increase levels of drugs metabolized by CYP3A4.
Read the full Black Chokeberry + Acetaminophen, Chlorpheniramine, Phenylpropanolamine, Opium interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Black Chokeberry 450 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Black Chokeberry
Anticoagulant/Antiplatelet Drugs
Theoretically, chokeberry might increase the risk of bleeding when taken with anticoagulant or antiplatelet drugs.
Clinical and in vitro research suggests that chokeberry extract can temporarily inhibit platelet aggregation and decrease clot formation.
Antidiabetes Drugs
Theoretically, chokeberry might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Some clinical research shows that chokeberry decreases levels of blood glucose in some patients with diabetes. However, other clinical research suggests that chokeberry has no significant effect on blood glucose levels.
Cytochrome P450 3A4 (Cyp3A4) Substrates
Theoretically, chokeberry might increase levels of drugs metabolized by CYP3A4.
In vitro research shows that chokeberry inhibits CYP3A4. In humans, there is one case report of a drug interaction with trabectedin, a CYP3A4 substrate, which is hypothesized to have been caused by chokeberry inhibition of CYP3A4.
Trabectedin (Yondelis)
Theoretically, chokeberry might increase the effects and adverse effects of trabectedin.
In one case report, a patient drinking chokeberry juice developed rhabdomyolysis induced by trabectedin, a cytochrome P450 3A4 (CYP3A4) substrate. It is possible that inhibition of CYP3A4 by chokeberry juice might have inhibited the metabolism of trabectedin and increased trabectedin levels in this patient.
Brand information
Manufacturer and brand details for Black Chokeberry 450 mg, from the product label.
TerraVita Premium Collection
See all TerraVita Premium Collection products- Name
- TerraVita Fine Whole Herbs
- City
- Brampton
- State
- Ontario
Black Chokeberry 450 mg by TerraVita Premium Collection: Common Questions
Does Black Chokeberry 450 mg by TerraVita Premium Collection interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Will black chokeberry help prevent heart disease?
What side effects should I expect?
Is it safe to take while breastfeeding?
What exactly is black chokeberry?
Is the 450 mg dose safe?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Black Chokeberry 450 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Black Chokeberry 450 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Black Chokeberry 450 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 8 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Chokeberry 8 references
- Sikora J, Broncel M, Markowicz M, Chalubinski M, Wojdan K, Mikiciuk-Olasik E. Short-term supplementation with Aronia melanocarpa extract improves platelet aggregation, clotting, and fibrinolysis in patients with metabolic syndrome. Eur J Nutr. 2012 Aug;51 PubMed
- Simeonov SB, Botushanov NP, Karahanian EB, Pavlova MB, Husianitis HK, Troev DM. Effects of Aronia melanocarpa juice as part of the dietary regimen in patients with diabetes mellitus. Folia Med (Plovdiv). 2002;44(3):20-3.
- Savikin K, Menkovic N, Zdunic G, Pljevljakusic D, Spasic S, Kardum N, Konic-Ristic A. Dietary supplementation with polyphenol-rich chokeberry juice improves skin morphology in cellulite. J Med Food. 2014 May;17(5):582-7. PubMed
- Bräunlich M, Christensen H, Johannesen S, Slimestad R, Wangensteen H, Malterud KE, Barsett H. In vitro inhibition of cytochrome P450 3A4 by Aronia melanocarpa constituents. Planta Med. 2013 Jan;79(2):137-41. PubMed
- Strippoli S, Lorusso V, Albano A, Guida M. Herbal-drug interaction induced rhabdomyolysis in a liposarcoma patient receiving trabectedin. BMC Complement Altern Med. 2013 Jul 30;13:199. PubMed
- Ryszawa N, Kawczynska-Drózdz A, Pryjma J, Czesnikiewicz-Guzik M, Adamek-Guzik T, Naruszewicz M, Korbut R, Guzik TJ. Effects of novel plant antioxidants on platelet superoxide production and aggregation in atherosclerosis. J Physiol Pharmacol. 2006 Dec;57(
- Milutinovic M, Velickovic Radovanovic R, Savikin K, et al. Chokeberry juice supplementation in type 2 diabetic patients - impact on health status. J Appl Biomed 2019;17(4):218-224. PubMed
- Lackner S, Sconocchia T, Ziegler T, et al. Immunomodulatory effects of aronia juice polyphenols-results of a randomized placebo-controlled human intervention study and cell culture experiments. Antioxidants (Basel) 2022;11(7):1283. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC