No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Black Walnut 500 mg Ingredients & Drug Interactions

by Solaray

Capsule Category: Botanical
No known interaction
The interaction bottom line No known interaction

Black Walnut 500 mg is a dietary supplement by Solaray with 1 active ingredient. Its ingredients are commonly taken for intestinal parasites and worms, digestive complaints, antimicrobial and antifungal support.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

HelloPharmacist Scorecard of Black Walnut 500 mg by Solaray

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: Black Walnut at 500 mg per capsule. The inactive ingredients are cellulose and rice bran extract, which serve as a capsule filler and binder.

Does it work?

No specific claim
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
General wellness

This Black Walnut product is marketed for general wellness, not a specific health condition, so there's no single claim to grade — see Black Walnut's own graded uses on its monograph.

Why this rating?
  • The label markets general wellness (“digestive support”), not a specific health condition, so there is no single claim to grade against clinical-evidence data.

The evidence for Black Walnut's effectiveness isn't established in the data we hold. For coronary heart disease and wound healing — the uses studied — we have insufficient reliable evidence to rate whether it works.

That doesn't mean it's ineffective, only that the clinical picture isn't clear enough yet to say.

The evidence, ingredient by ingredient Black Walnut

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Black Walnut is generally well tolerated when taken orally as a nut, though human safety data are limited and long-term use hasn't been well studied — so short-term use is what we know most about. The leaf, bark, and hull of the plant contain high quantities of tannins, which can cause gastrointestinal upset if ingested.

Tree nuts, including black walnuts, can trigger allergic reactions in sensitive people; tree nuts are a major food allergen in the United States. Because of limited safety information, Black Walnut is best avoided during pregnancy and while breastfeeding.

Side effects, ingredient by ingredient Black Walnut

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for Black Walnut. Check your exact medications with the tool on this page to be thorough.

The bottom line

Scorecard at a glanceFully disclosed formula marketed for general wellness rather than one specific gradeable purpose. No medication interactions are currently documented, and safety information is well characterized.

Black Walnut may be worth trying short-term if you're exploring its traditional uses, but understand that evidence for its effectiveness isn't established yet. If you're pregnant, breastfeeding, or allergic to tree nuts, steer clear.

Talk to your pharmacist if you have questions about whether it's right for your situation.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Sep 25, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Black Walnut 500 mg, straight from the product label.

Brand Solaray
Barcode (UPC) 076280001808
Net contents 100 VegCap(s)
Market status On market
Date entered into DSLD Sep 25, 2025
DSLD ID 338859
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Black Walnut 500 mg by Solaray, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 VegCap(s)
Maximum serving Sizes:
1 VegCap(s)
Servings per container
100
UPC/BARCODE
076280001808
IngredientAmount% DV
Black Walnut500 mg--

Other ingredients: Cellulose, Rice Bran Extract

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

Solaray Est. 1973 A Brighter Way 1973

General Statements

True Herbs

Since 1973, we've scoured the globe for the highest quality ingredients, connecting you with the most efficacious supplements that help you live brighter & embrace the moments that matter most.

100% PCR Bottles

Formulation

Digestive support

Vegan

FDA Statement of Identity

Dietary Supplements

Seals/Symbols

Lab Verified Vegan

Precautions

Warning: Do not use if safety seal is broken or missing. Keep your licensed health care practitioner informed when using this product. Not recommended for excessive or long term use.

Keep out of reach of children.

California Residents Only Warning: Reproductive harm - www.P65Warning.ca.gov

Suggested/Recommended/Usage/Directions

Directions: Use only as directed. Take 1 VegCap daily with a meal or glass of water.

Storage

Store in a cool, dry place.

Formula

Discussion: Originating ancient in Persia, black walnut hulls have a long history of use throughout the world. Black walnut hulls contain a phytochemical known as juglone, believed be the source of its health benefits. Black walnut may provide nutritive support for intestinal wellness.

FDA Disclaimer Statement

These statements have not been evaluated by the FDA. This product is not intended to diagnose, treat, cure or prevent any disease.

See for yourself

Black Walnut 500 mg by Solaray label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Black Walnut 500 mg by Solaray

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 VegCap(s) Dosage formCapsule Servings per container100 Amounts shown are per serving.

Black Walnut

No known
interactions
500 mg per serving

Black walnut is a tree whose green hulls are traditionally used as a natural antiparasitic and digestive remedy, but solid human evidence for these us...

Black Walnut monograph & interactions

Other (inactive) ingredients: Cellulose, Rice Bran Extract. These complete the product’s ingredient list but are not active constituents.

Interaction report

Black Walnut 500 mg by Solaray Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Black Walnut 500 mg. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Black Walnut 500 mg, from the product label.

Solaray

See all Solaray products
Name
Nutraceutical Corp.
Web Address
www.nutraceutical.com
Pharmacist Counseling Corner

Black Walnut 500 mg by Solaray: Common Questions

Does Black Walnut 500 mg by Solaray interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Black Walnut 500 mg. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Black Walnut 500 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will Black Walnut interact with my medications?
No interactions are documented in our data for Black Walnut. That said, run your specific medications through the checker on this page to be certain — the absence of documented interactions isn't a guarantee none exist.
Can I take Black Walnut if I'm pregnant or breastfeeding?
No. Safety data advise against Black Walnut during pregnancy and while breastfeeding due to insufficient information. Talk with your doctor or pharmacist before use if you're pregnant or nursing.
Can Black Walnut cause side effects?
The nut itself is well tolerated, but the leaf, bark, and hull contain high quantities of tannins and can cause stomach upset. Tree nuts are also a common allergen, so allergic reactions are possible in sensitive individuals.
Does Black Walnut actually work for heart health or wound healing?
The evidence isn't clear yet. For both coronary heart disease and wound healing, we have insufficient reliable evidence to rate whether Black Walnut is effective — so it's not yet established whether it works for these purposes.
How long is it safe to take Black Walnut?
Short-term use is what we know most about; human safety data are limited and long-term use hasn't been well studied. Chat with your pharmacist about how long is right for you.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Black Walnut 500 mg is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Black Walnut 500 mg label
Go deeper

The Full Monographs Behind Black Walnut 500 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Black Walnut 500 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 3 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Black Walnut 3 references
  1. Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
  2. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  3. Food and Drug Administration. Food Allergen Labeling and Consumer Protection Act of 2004 (FALCPA); Public Law 108-282, Title II. Accessed on May 19, 2021. Available at: https://www.fda.gov/food/food-allergensgluten-free-guidance-documents-regulatory-infor

See these in context on the Black Walnut monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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