No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Black Walnut Hulls Ingredients & Drug Interactions

by Pure Herbs

Black Walnut Hulls label
See full label image
Liquid Category: Botanical
No known interaction
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Black Walnut Hulls against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line No known interaction

Black Walnut Hulls is a dietary supplement by Pure Herbs with 1 active ingredient. Its ingredients are commonly taken for intestinal parasites and worms, digestive complaints, antimicrobial and antifungal support.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

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HelloPharmacist Scorecard of Black Walnut Hulls by Pure Herbs

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 16, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: Black Walnut Husk Extract. The husk — the outer covering of the black walnut — is what's being used here.

The product comes as a liquid, which makes it easy to dose and absorb.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

We hold no graded evidence for this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: healthy nerve function.
  • We looked for evidence on: neuropathy, nerve health, neurological function, peripheral nerve disease.
  • Our graded evidence for these ingredients doesn't cover that particular purpose.

The evidence isn't established in the data we hold. We have insufficient reliable evidence to rate Black Walnut Husk Extract for coronary heart disease or wound healing.

That doesn't mean it doesn't work; it means the studies we can point to aren't solid enough yet to make a confident claim either way.

The evidence, ingredient by ingredient Black Walnut

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Black Walnut Husk Extract is generally well tolerated for short-term use in most adults, but human safety data are limited and long-term use hasn't been well studied. The hull contains high quantities of tannins, which can trigger gastrointestinal upset — nausea, stomach discomfort, or changes in bowel habits — when you take it by mouth.

Tree nuts, including black walnuts, can cause allergic reactions in people with a tree nut allergy, which is fairly common. During pregnancy, there isn't enough safety information; the data advises against it.

While breastfeeding, the same caution applies — avoid it unless you've talked it over with your doctor or pharmacist.

Side effects, ingredient by ingredient Black Walnut

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for Black Walnut Husk Extract.

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. No medication interactions are currently documented, and safety information is well characterized.

This product is an option if you're exploring Black Walnut for short-term use and you don't have a tree nut allergy, but the evidence for what it does isn't established yet, and long-term safety isn't well understood. If you're pregnant, breastfeeding, or taking any medications, talk it over with your own doctor or pharmacist before starting.

Stop and reach out if you notice stomach upset or any sign of an allergic reaction.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Dec 13, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Black Walnut Hulls, straight from the product label.

Brand Pure Herbs
Net contents 4 Fluid Ounce(s); 120 mL
Market status On market
Date entered into DSLD Dec 13, 2022
DSLD ID 279177
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Black Walnut Hulls by Pure Herbs, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 mL
Maximum serving Sizes:
2 mL
Servings per container
60
IngredientAmount% DV
Black Walnut Husk Extract1866 mg--

Other ingredients: None

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions: For adults, mix 2 mL (abt. 1/2 tsp) of extract in 2 fl. oz (60 mL) water one time daily preferably with a meal.

Shake well before use

Formulation

Beneficial for healthy nerve function.

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Precautions

Warning: Not intended for use by pregnant or nursing women. If you have a medical condition or are taking medication, consult your doctor prior to use.

Discontinue use and consult with your doctor if any adverse reactions occur.

Keep out of reach of children

Contains: Walnuts

Brand IP Statement(s)

Pure Herbs, Ltd. Natural Herbal Extracts

FDA Statement of Identity

Dietary Supplement

General Statements

"No expense has been spared to provide the finest nature has to offer."

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Black Walnut Hulls by Pure Herbs label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Black Walnut Hulls label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Black Walnut Hulls by Pure Herbs

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 mL Dosage formLiquid Servings per container60 Amounts shown are per serving.

Black Walnut Husk Extract

No known
interactions
1866 mg per serving

Black walnut is a tree whose green hulls are traditionally used as a natural antiparasitic and digestive remedy, but solid human evidence for these us...

Black Walnut Husk Extract monograph & interactions

Other (inactive) ingredients: None. These complete the product’s ingredient list but are not active constituents.

Interaction report

Black Walnut Hulls by Pure Herbs Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Black Walnut Hulls. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Black Walnut Hulls, from the product label.

Pure Herbs

See all Pure Herbs products
Name
Pure Herbs, Ltd.
City
Sterling Heights
State
MI
Phone Number
(800) 860-4372
Web Address
www.pureherbs.com
Pharmacist Counseling Corner

Black Walnut Hulls by Pure Herbs: Common Questions

Does Black Walnut Hulls by Pure Herbs interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Black Walnut Hulls. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Black Walnut Hulls contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this while pregnant?
There isn't enough safety information for pregnancy. The data advises against it. Talk with your own doctor or pharmacist about whether it's right for you.
Can I take this while breastfeeding?
There isn't enough safety information for breastfeeding either. The same caution applies — avoid it unless you've cleared it with your own doctor or pharmacist first.
Does black walnut husk cause side effects?
The most common one is gastrointestinal upset — stomach discomfort or changes in bowel habits — because the hull is high in tannins. Tree nuts can also trigger allergic reactions in sensitive people. Stop and seek care if you notice signs of an allergy or severe stomach symptoms.
How long can I safely take this?
Short-term use is generally okay for most adults, but human safety data are limited and long-term use hasn't been well studied. If you're thinking about using it beyond a few weeks, check in with your own pharmacist or doctor first.
Does this help with heart health or wound healing?
The evidence isn't established yet. We have insufficient reliable evidence to rate Black Walnut Husk Extract for either coronary heart disease or wound healing, so we can't say whether it works for those uses.
Is this safe if I have a tree nut allergy?
No — black walnuts are tree nuts, and they can cause allergic reactions in sensitive people. If you have a tree nut allergy, avoid this product and talk with your own doctor or pharmacist.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Black Walnut Hulls is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Black Walnut Hulls label
Go deeper

The Full Monographs Behind Black Walnut Hulls’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Black Walnut

Black walnut is a tree whose green hulls are traditionally used as a natural antiparasitic and digestive remedy, but solid human evidence for these uses is lacking. It contains a compound ca...

Read the full Black Walnut monograph →
Sources

Sources & How We Checked

Black Walnut Hulls's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 3 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Black Walnut 3 references
  1. Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
  2. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  3. Food and Drug Administration. Food Allergen Labeling and Consumer Protection Act of 2004 (FALCPA); Public Law 108-282, Title II. Accessed on May 19, 2021. Available at: https://www.fda.gov/food/food-allergensgluten-free-guidance-documents-regulatory-infor

See these in context on the Black Walnut monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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