No known drug interactions for the matched ingredients — not a guarantee none exist. Check your meds →
Dietary supplement

Black Walnut Hulls Ingredients & Drug Interactions

by Pure Herbs

Black Walnut Hulls label
See full label image
Liquid Category: Botanical
No known interaction
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Black Walnut Hulls against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line No known interaction

Black Walnut Hulls is a dietary supplement by Pure Herbs with 1 active ingredient. Its ingredients are commonly taken for intestinal parasites and worms, digestive complaints, antimicrobial and antifungal support.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.

Jump to a section

HelloPharmacist Scorecard of Black Walnut Hulls by Pure Herbs

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 16, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: Black Walnut Husk Extract. Black walnut hulls have been used traditionally, though the evidence for specific health claims remains limited.

The product is a liquid form, which may aid absorption. There are no inactive ingredients listed.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

We hold no graded evidence for this product's ingredients for its stated purpose.

Why this rating?
  • The label markets this product for: healthy nerve function.
  • We looked for evidence on: neuropathy, peripheral nerve health, neurological function.
  • Our graded evidence for these ingredients doesn't cover that particular purpose.

The evidence for Black Walnut Husk Extract is not yet established in the data we hold. For both coronary heart disease and wound healing — the uses we have ratings for — the evidence is insufficient to make a reliable assessment.

If you're considering this for a specific health goal, talk with your doctor or pharmacist about whether the current evidence supports it for your situation.

The evidence, ingredient by ingredient Black Walnut

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Black walnut hulls are generally well tolerated when taken by mouth, but safety data in humans are limited and long-term use hasn't been well studied. The hull contains high quantities of tannins, which can cause gastrointestinal upset — nausea, stomach discomfort, or other digestive symptoms — in some people.

Tree nuts, including black walnuts, can trigger allergic reactions in sensitive individuals; if you have a tree nut allergy, avoid this product. Daily use of walnut bark (a related part of the plant) has been linked to an increased risk of tongue cancer and lip leukoplakia, so prolonged daily use warrants caution.

Side effects, ingredient by ingredient Black Walnut

Meds to double-check

No known interactions
Known Interaction Concern · database check
No known interactions

No medication interactions are currently documented for the matched ingredients — that isn't a guarantee none exist.

Why this rating?
  • None of the 1 matched ingredient has a documented medication interaction on file.

No interactions are documented in our data for the ingredient we checked. This is not a guarantee that none exist — it means we hold no interaction monograph for Black Walnut Husk Extract.

If you take any medications, run them through the checker on this page to confirm.

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. No medication interactions are currently documented, and safety information is well characterized.

Black Walnut Hulls may appeal to those interested in traditional herbal use, but the health evidence is limited and long-term safety isn't well studied. If you have a tree nut allergy or are pregnant or breastfeeding, talk with your doctor or pharmacist first — the safety data don't support use in those situations.

For everyone, discuss this with your own healthcare provider before starting, especially if you plan to take it daily for an extended time.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Dec 13, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Black Walnut Hulls, straight from the product label.

Brand Pure Herbs
Net contents 1 Fluid Ounce(s); 30 mL
Market status On market
Date entered into DSLD Dec 13, 2022
DSLD ID 278743
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Women (not pregnant or lactating)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Black Walnut Hulls by Pure Herbs, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 mL
Maximum serving Sizes:
2 mL
Servings per container
15
IngredientAmount% DV
Black Walnut Husk Extract1866 mg--

Other ingredients: None

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Directions: For adults, mix 2 mL (abt. 1/2 tsp) of extract in 2 fl. oz (60 mL) water one time daily preferably with a meal.

Shake well before use

Formulation

Beneficial for healthy nerve function.

FDA Disclaimer Statement

This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Precautions

Warning: Not intended for use by pregnant or nursing women. If you have a medical condition or are taking medication, consult your doctor prior to use.

Discontinue use and consult with your doctor if any adverse reactions occur.

Keep out of reach of children

Contains: Walnuts

Brand IP Statement(s)

Pure Herbs, Ltd. Natural Herbal Extracts

FDA Statement of Identity

Dietary Supplement

General Statements

"No expense has been spared to provide the finest nature has to offer."

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Black Walnut Hulls by Pure Herbs label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Black Walnut Hulls label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Black Walnut Hulls by Pure Herbs

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 mL Dosage formLiquid Servings per container15 Amounts shown are per serving.

Black Walnut Husk Extract

No known
interactions
1866 mg per serving

Black walnut is a tree whose green hulls are traditionally used as a natural antiparasitic and digestive remedy, but solid human evidence for these us...

Black Walnut Husk Extract monograph & interactions

Other (inactive) ingredients: None. These complete the product’s ingredient list but are not active constituents.

Interaction report

Black Walnut Hulls by Pure Herbs Drug Interactions

We don’t currently list any known drug interactions for the mapped ingredients in Black Walnut Hulls. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.

The maker

Brand information

Manufacturer and brand details for Black Walnut Hulls, from the product label.

Pure Herbs

See all Pure Herbs products
Name
Pure Herbs, Ltd.
City
Sterling Heights
State
MI
Phone Number
(800) 860-4372
Web Address
www.pureherbs.com
Pharmacist Counseling Corner

Black Walnut Hulls by Pure Herbs: Common Questions

Does Black Walnut Hulls by Pure Herbs interact with any medications?
We do not currently list a known interaction for the mapped ingredients in Black Walnut Hulls. This does not guarantee none exist, so confirm with your pharmacist.
How can one product interact with so many drugs?
Black Walnut Hulls contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take Black Walnut Hulls if I have a tree nut allergy?
No. Black walnuts are tree nuts, and they can trigger allergic reactions in people with tree nut allergies. Tree nut allergy is common in the U.S. population, so if you have one, this product should be avoided. Talk to your allergist or pharmacist to be sure.
Will Black Walnut Hulls help my digestion or upset my stomach?
The opposite is likely. Black walnut hulls contain high amounts of tannins, which may cause gastrointestinal upset — nausea, discomfort, or other digestive problems — when taken by mouth. If you have a sensitive stomach, this is something to be cautious about.
Is it safe to take Black Walnut Hulls while pregnant or breastfeeding?
The safety data advise against it. During pregnancy, there isn't enough information to know whether it's safe, so it's best avoided. While breastfeeding, the same applies — there's not enough data, so it's recommended to avoid it. Talk with your doctor or midwife before considering it.
Does Black Walnut Hull Extract really help with heart disease or wound healing?
The evidence isn't established yet in the data we hold. For both coronary heart disease and wound healing, the research is insufficient to make a reliable claim. If you're thinking about using it for one of these purposes, ask your doctor whether the current evidence supports it for you.
How long can I safely take Black Walnut Hulls?
Short-term use is generally acceptable for most adults, but long-term safety hasn't been well studied. If you're planning to take it regularly for weeks or months, talk with your pharmacist or doctor about whether that's appropriate for you.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Black Walnut Hulls is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Black Walnut Hulls label
Go deeper

The Full Monographs Behind Black Walnut Hulls’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Black Walnut

Black walnut is a tree whose green hulls are traditionally used as a natural antiparasitic and digestive remedy, but solid human evidence for these uses is lacking. It contains a compound ca...

Read the full Black Walnut monograph →
Sources

Sources & How We Checked

Black Walnut Hulls's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 3 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Black Walnut 3 references
  1. Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
  2. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  3. Food and Drug Administration. Food Allergen Labeling and Consumer Protection Act of 2004 (FALCPA); Public Law 108-282, Title II. Accessed on May 19, 2021. Available at: https://www.fda.gov/food/food-allergensgluten-free-guidance-documents-regulatory-infor

See these in context on the Black Walnut monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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