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Dietary supplement

Black Walnut Wormwood Complex Ingredients & Drug Interactions

by LuckyHerbs

Liquid Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Black Walnut Wormwood Complex is a dietary supplement by LuckyHerbs with 1 active ingredient. Its ingredients are commonly taken for intestinal parasites and worms, digestive complaints, antimicrobial and antifungal support.Based on those ingredients, 1,014 medications have a known interaction with it, the most serious rated moderate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Black Walnut Wormwood Complex by LuckyHerbs

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 3 active ingredients.
  • “Black Walnut Wormwood Complex” is a proprietary blend — the label gives one combined amount (1.60 mL) without saying how much of each component you get.

Black Walnut Wormwood Complex contains three active ingredients. Black walnut husk extract is included for its traditional use, though evidence for its effectiveness in coronary heart disease or wound healing is insufficient.

Wormwood herb extract is a traditional digestive and anti-inflammatory botanical, but again evidence for conditions like dyspepsia, Crohn disease, or osteoarthritis is insufficient at this time. Clove bud extract rounds out the formula; there is possibly effective evidence for its use in ventilator-associated pneumonia, though evidence for cough, acute pain, and dyspepsia is insufficient.

The liquid also contains grain alcohol and water as inactive ingredients.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded its ingredients' overall clinical evidence instead.

Moderate

Some clinical evidence supports its ingredients for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredients' overall clinical evidence instead.
  • On file: Ventilator-associated pneumonia (VAP) — rated "Possibly Effective" (Clove) (Natural Medicines).

The evidence on file for the active ingredients in this product is limited. Black walnut husk and wormwood have insufficient reliable evidence to support their use for the conditions they're traditionally marketed for — coronary heart disease, wound healing, dyspepsia, Crohn disease, depression, osteoarthritis, and biliary disorders are all listed as insufficiently studied.

Clove bud extract has possibly effective evidence for ventilator-associated pneumonia, but insufficient evidence for cough, acute pain, and dyspepsia. If you're considering this product for a specific health concern, talk with your pharmacist about what the actual evidence shows.

The evidence, ingredient by ingredient Black Walnut Wormwood Clove

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 3 of the 3 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 3 of 3.
  • General safety write-ups exist for 3 of 3.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Black walnut husk extract is well tolerated orally when the nut meat is consumed, but the hull contains high tannins that may cause gastrointestinal upset. Short-term use is likely acceptable for most adults, though long-term safety isn't well studied.

The safety data advises against use during pregnancy and breastfeeding. Wormwood contains thujone, a neurotoxin, and short-term use of properly prepared products may be acceptable, but higher amounts can be toxic.

Oral wormwood oil can cause muscle aches, nausea, and vomiting; rare serious effects include kidney toxicity, rhabdomyolysis, and seizures. The safety data advises against use during pregnancy and breastfeeding.

Clove is safe as a food spice but concentrated oils and supplements can be irritating or toxic in large amounts — even 5–10 mL of clove oil can be toxic in children. Topical use generally causes mild irritation; serious effects like liver failure are rare.

Food amounts during pregnancy and breastfeeding are likely safe, but medicinal doses lack sufficient data.

Side effects, ingredient by ingredient Black Walnut Wormwood Clove

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 2 of the 3 matched ingredients can interact with medications — Clove, Wormwood.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; seizure medications; diabetes medications.
  • For scale: 1,015 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check anticonvulsant drugs (seizure medications) with your pharmacist — wormwood may reduce their effectiveness (Moderate). Also verify diabetes medications, because clove may increase low blood sugar risk (Moderate).

Check any medications metabolized by the liver enzymes CYP2D6, CYP1A2, CYP3A4, or CYP2C9 — clove may theoretically raise their levels (Moderate). Finally, let your pharmacist know if you take blood thinners, antiplatelet drugs, or topical ibuprofen, as clove has minor theoretical interactions with these (Minor).

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

This product is a blend of three traditional botanicals with limited evidence of effectiveness and several medication interactions you should check first — especially if you take seizure drugs, diabetes medications, or blood thinners. Black walnut is best used short-term, and wormwood should be avoided in pregnancy and breastfeeding.

Talk to your pharmacist before starting, particularly if you take any prescription or over-the-counter medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 3 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Mar 22, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Black Walnut Wormwood Complex, straight from the product label.

Brand LuckyHerbs
Barcode (UPC) 810026421792
Net contents 2 Fluid Ounce(s); 59 mL
Market status On market
Date entered into DSLD Mar 22, 2023
DSLD ID 283126
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Women (not pregnant or lactating), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Black Walnut Wormwood Complex by LuckyHerbs, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
0.4 mL
Maximum serving Sizes:
1.6 mL
Servings per container
37
UPC/BARCODE
810026421792
IngredientAmount% DV
Black Walnut Wormwood Complex1.6 mL--
Black Walnut Husk Extract0 NP--
Wormwood herb extract0 NP--
Clove bud extract0 NP--

Other ingredients: Grain Alcohol, Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Usage: Take 1/2 to 2 droppersful 2 times daily in juice or water before meals and/or at bedtime. This product is best used by gradually increasing dosage over a two week period with a one week break before repeating.

Precautions

Caution: For adults only.

Not for pregnant/nursing women. Consult physician if taking medication or have a medical condition.

Individuals with kidney or liver dysfunction should avoid taking this supplement. May cause gastrointestinal disturbance. Contains alcohol.

Keep out of reach of children.

Contains tree nut (black walnut).

Not manufactured with yeast, wheat, gluten, soy, milk, egg, fish or shellfish ingredients. Produced in a GMP facility that processes other ingredients containing these allergens.

Formulation

Natural color variation may occur in this product.

Not manufactured with yeast, wheat, gluten, soy, milk, egg, fish or shellfish ingredients.

Non-GMO

Vegan

Storage

Store in a cool, dry place after opening.

General Statements

1 year happiness guarantee

Brand IP Statement(s)

Lucky Herbs Herbal Supplements by Lucky Vitamin

FDA Statement of Identity

Dietary Supplement

Seals/Symbols

Guaranteed Quality & Potency

See for yourself

Black Walnut Wormwood Complex by LuckyHerbs label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Black Walnut Wormwood Complex by LuckyHerbs

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size0.4 mL Dosage formLiquid Servings per container37 Amounts shown are per serving.

Black Walnut Wormwood Complex

No known
interactions
1.6 mL per serving

Black walnut is a tree whose green hulls are traditionally used as a natural antiparasitic and digestive remedy, but solid human evidence for these us...

Black Walnut Wormwood Complex monograph & interactions

Other (inactive) ingredients: Grain Alcohol, Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Black Walnut Wormwood Complex by LuckyHerbs Drug Interactions

Want to check YOUR meds against Black Walnut Wormwood Complex?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
1,014Drugs
954 Moderate 60 Minor

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Black Walnut Wormwood Complex with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

The maker

Brand information

Manufacturer and brand details for Black Walnut Wormwood Complex, from the product label.

LuckyHerbs

See all LuckyHerbs products
Name
Lucky Health Group Inc.
City
Conshohocken
State
PA
ZipCode
19428
Phone Number
1-888-635-0474
Web Address
www.LuckyVitamin.com
Pharmacist Counseling Corner

Black Walnut Wormwood Complex by LuckyHerbs: Common Questions

Does Black Walnut Wormwood Complex by LuckyHerbs interact with any medications?
Yes. Based on its ingredients, Black Walnut Wormwood Complex has a known interaction with 1,014 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Black Walnut Wormwood Complex contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe during pregnancy or while breastfeeding?
No — both wormwood and black walnut are advised against during pregnancy and breastfeeding due to insufficient safety data. Wormwood is specifically considered unsafe in pregnancy because it may stimulate the uterus. Talk with your doctor or pharmacist before using any herbal product during pregnancy or lactation.
What's in this that could cause side effects?
Wormwood contains thujone, a compound that can cause nausea, vomiting, and muscle aches, especially at higher doses. Black walnut husk has tannins that may upset your stomach. Clove oil in large amounts can irritate your mouth and throat. Food-level amounts of clove are generally fine, but this is a concentrated supplement.
Can I take this if I have a tree nut allergy?
Black walnut is a tree nut and can trigger allergic reactions in sensitive individuals. If you have a tree nut allergy, you should avoid this product and talk with your pharmacist or allergist first.
Does this product actually work?
The evidence on file is very limited. Black walnut and wormwood lack sufficient reliable evidence for the conditions they're traditionally used for. Clove has possibly effective evidence only for ventilator-associated pneumonia, not for cough, pain, or digestion. This is a traditional blend, but the science doesn't back most uses.
How long is it safe to use this?
Black walnut and wormwood are best used short-term — long-term safety isn't well studied. Wormwood is especially concerning because thujone can build up and become toxic with chronic use. Clove as a food spice is fine long-term, but medicinal doses lack sufficient data. Talk with your pharmacist about duration before starting.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Black Walnut Wormwood Complex is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Black Walnut Wormwood Complex label
Sources

Sources & How We Checked

Black Walnut Wormwood Complex's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 39 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Black Walnut 3 references
  1. Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
  2. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  3. Food and Drug Administration. Food Allergen Labeling and Consumer Protection Act of 2004 (FALCPA); Public Law 108-282, Title II. Accessed on May 19, 2021. Available at: https://www.fda.gov/food/food-allergensgluten-free-guidance-documents-regulatory-infor

See these in context on the Black Walnut monograph →

Wormwood 10 references
  1. Weisbord SD, Soule JB, Kimmel PL. Poison on line-acute renal failure caused by oil of wormwood purchased through the internet. N Engl J Med 1997;337:825-7. PubMed
  2. Gambelunghe C, Melai P. Absinthe: enjoying a new popularity among young people? Forensic Sci Int 2002;130:183-6.
  3. Hold KM, Sirisoma NS, Casida JE. Detoxification of alpha- and beta-Thujones (the active ingredients of absinthe): site specificity and species differences in cytochrome P450 oxidation in vitro and in vivo. Chem Res Toxicol 2001;14:589-95.
  4. Lachenmeier DW, Walch SG, Padosch SA, Kroner LU. Absinthe--a review. Crit Rev Food Sci Nutr 2006;46:365-77.
  5. Padosch SA, Lachenmeier DW, Kroner LU. Absinthism: a fictitious 19th century syndrome with present impact. Subst Abuse Treat Prev Policy 2006;1:14. PubMed
  6. Lachenmeier DW, Emmert J, Kuballa T, Sartor G. Thujone--cause of absinthism? Forensic Sci Int 2006;158:1-8. PubMed
  7. Dettling, A., Grass, H., Schuff, A., Skopp, G., Strohbeck-Kuehner, P., and Haffner, H. T. Absinthe: attention performance and mood under the influence of thujone. J Stud.Alcohol 2004;65(5):573-581. PubMed
  8. Benezet-Mazuecos, J. and de la Fuente, A. Electrocardiographic findings after acute absinthe intoxication. Int J Cardiol. 11-10-2006;113(2):e48-e50. PubMed
  9. El Makrini NI, Hassam B. Artemisia absinthium: burning plant! Pan Afr Med J. 2016 Jan 22;23:10. PubMed
  10. Kocaoglu C, Ozel A. Persistent metabolic acidosis and severe diarrhoea due to Artemisia absinthium poisoning. J Pak Med Assoc. 2014 Sep;64(9):1081-3.

See these in context on the Wormwood monograph →

Clove 26 references
  1. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  2. Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
  3. Kanerva L, Estlander T, Jolanki R. Occupational allergic contact dermatitis from spices. Contact Dermatitis 1996;35:157-62. PubMed
  4. Chen SJ, Wang MH, Chen IJ. Antiplatelet and calcium inhibitory properties of eugenol and sodium eugenol acetate. Gen Pharmacol 1996;27:629-33. PubMed
  5. Malson JL, Lee EM, Murty R, et al. Clove cigarette smoking: biochemical, physiological, and subjective effects. Pharmacol Biochem Behav 2003;74:739-45. PubMed
  6. Kirsch CM, Yenokida GG, Jensen WA, et al. Non-cardiogenic pulmonary oedema due to the intravenous administration of clove oil. Thorax 1990;45:235-6. PubMed
  7. Pallares, D. E. Link between clove cigarettes and urticaria? Postgrad.Med 10-1-1999;106(4):153. PubMed
  8. Barnard, D. R. Repellency of essential oils to mosquitoes (Diptera: Culicidae). J Med Entomol. 1999;36(5):625-629. PubMed
  9. Sanchez-Perez, J. and Garcia-Diez, A. Occupational allergic contact dermatitis from eugenol, oil of cinnamon and oil of cloves in a physiotherapist. Contact Dermatitis 1999;41(6):346-347. PubMed
  10. Andersen, K. E., Johansen, J. D., Bruze, M., Frosch, P. J., Goossens, A., Lepoittevin, J. P., Rastogi, S., White, I., and Menne, T. The time-dose-response relationship for elicitation of contact dermatitis in isoeugenol allergic individuals. Toxicol.Appl PubMed
  11. Alqareer, A., Alyahya, A., and Andersson, L. The effect of clove and benzocaine versus placebo as topical anesthetics. J Dent 2006;34(10):747-750. PubMed
  12. Lane, B. W., Ellenhorn, M. J., Hulbert, T. V., and McCarron, M. Clove oil ingestion in an infant. Hum.Exp Toxicol. 1991;10(4):291-294. PubMed
  13. Quirce, S., Fernandez-Nieto, M., del, Pozo, V, Sastre, B., and Sastre, J. Occupational asthma and rhinitis caused by eugenol in a hairdresser. Allergy 2008;63(1):137-138. PubMed
  14. Srivastava, K. C. and Malhotra, N. Acetyl eugenol, a component of oil of cloves (Syzygium aromaticum L.) inhibits aggregation and alters arachidonic acid metabolism in human blood platelets. Prostaglandins Leukot.Essent.Fatty Acids 1991;42(1):73-81. PubMed
  15. Dyrbye, B. A., Dubois, L., Vink, R., and Horn, J. A patient with clove oil intoxication. Anaesth.Intensive Care 2012;40(2):365-366.
  16. Guidotti, T. L., Laing, L., and Prakash, U. B. Clove cigarettes. The basis for concern regarding health effects. West J Med 1989;151(2):220-228.
  17. Anonymous. Evaluation of the health hazard of clove cigarettes. Council on Scientific Affairs. JAMA 12-23-1988;260(24):3641-3644. DOI
  18. Romaguera, C., Alomar, A., Camarasa, J. M., Garcia, Bravo B., Garcia, Perez A., Grimalt, F., Guerra, P., Lopez, Gorretcher B., Pascual, A. M., Miranda, A., and . Contact dermatitis in children. Contact Dermatitis 1985;12(5):283-284. PubMed
  19. Hackett, P. H., Rodriguez, G., and Roach, R. C. Clove cigarettes and high-altitude pulmonary edema. JAMA 6-28-1985;253(24):3551-3552. DOI
  20. Isaacs, G. Permanent local anaesthesia and anhidrosis after clove oil spillage. Lancet 4-16-1983;1(8329):882. PubMed
  21. Saeed, S. A. and Gilani, A. H. Antithrombotic activity of clove oil. J Pak Med Assoc 1994;44(5):112-115.
  22. Hartnoll, G., Moore, D., and Douek, D. Near fatal ingestion of oil of cloves. Arch.Dis Child 1993;69(3):392-393. PubMed
  23. Srivastava, K. C. Antiplatelet principles from a food spice clove (Syzygium aromaticum L) [corrected]. Prostaglandins Leukot.Essent.Fatty Acids 1993;48(5):363-372.
  24. Jiang Q, Wu Y, Zhang H, et al. Development of essential oils as skin permeation enhancers: penetration enhancement effect and mechanism of action. Pharmaceutical Biol. 2017;55(1):1592-1600. PubMed
  25. Mohan R, Jose S, Mulakkal J, Karpinsky-Semper D, Swick AG, Krishnakumar IM. Water-soluble polyphenol-rich clove extract lowers pre- and post-prandial blood glucose levels in healthy and prediabetic volunteers: an open label pilot study. BMC Complement Alt PubMed
  26. Alharbi NFM, Ahad A, Bin Jardan YA, Al-Jenoobi FI. Effect of eugenol on cytochrome P450 1A2, 2C9, 2D6, and 3A4 activity in human liver microsomes. Saudi Pharm J 2024;32(7):102118. PubMed

See these in context on the Clove monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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