Interactions on record — worth a quick check against your medications. Based on 4 of 6 ingredients. Check your meds →
Dietary supplement

Bladder Health Ingredients & Drug Interactions

by Emerald Labs

Bladder Health label
See full label image
Capsule Category: Botanical With Nutrients
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Bladder Health against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Bladder Health is a dietary supplement by Emerald Labs with 6 active ingredients. Its ingredients are commonly taken for heart and cholesterol support, antioxidant support, liver health (fatty liver).Based on those ingredients, 935 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are PACran, Horsetail, Tocotriene Complex. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

Jump to a section

Check Your Meds Against Bladder Health by Emerald Labs

Ask about any prescription or over-the-counter medication and we check it for interactions with Bladder Health by Emerald Labs — and tell you which ingredient is responsible.

Pharmacist-reviewed data Checks every ingredient Answer in seconds
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HelloPharmacist Scorecard of Bladder Health by Emerald Labs

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 16, 2026

What’s inside

Partial disclosure
Ingredient Transparency · database check
Partial

Most active ingredients list an amount, but at least one is hidden in a blend or missing.

Why this rating?
  • The label discloses an exact amount for 3 of its 6 active ingredients.
  • “Urox Blend” is a proprietary blend — the label gives one combined amount (840 mg) without saying how much of each component you get.

Bladder Health contains 6 ingredients. The active ones are Tocotriene Complex (a form of vitamin E), Pumpkin seed extract, Urox Blend, Lindera aggregata, Horsetail, and PACran (cranberry).

The product also contains a vegetable capsule as an inactive ingredient. Each of these plays a role in supporting bladder function, though the strength of the evidence varies.

Pumpkin seed extract is possibly effective for benign prostatic hyperplasia (BPH), and cranberry is possibly effective for urinary tract infections (UTIs). The others have insufficient evidence for their intended use, or we lack reliable data on their effectiveness.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: support muscle tone and bladder comfort.
  • We looked for evidence on: Overactive bladder, Benign prostatic hyperplasia (BPH), Urinary incontinence, Urinary tract infections (UTIs), Interstitial cystitis, Radiation-induced cystitis — and 2 related terms.
  • The strongest evidence on file: Pumpkin is rated "Possibly Effective" for Benign prostatic hyperplasia (BPH) (Natural Medicines).
  • Also on file: Cranberry is rated "Possibly Effective" for Urinary tract infections (UTIs).
  • Also on file: Pumpkin is rated "Insufficient Reliable Evidence To Rate" for Interstitial cystitis, Urinary tract infections (UTIs), Overactive bladder.

The evidence for this product's ingredients is mixed. Cranberry (PACran) is possibly effective for urinary tract infections, making it the strongest-supported ingredient here.

Pumpkin seed extract is possibly effective for benign prostatic hyperplasia (enlarged prostate). For the other ingredients — Tocotriene Complex, Horsetail, and the two we cannot fully assess (Lindera aggregata and Cratevox) — we either lack sufficient reliable evidence or hold no data on file to rate their effectiveness for bladder health.

The evidence, ingredient by ingredient Tocotrienols Pumpkin Horsetail Cranberry

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 4 of the 4 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 4 of 4.
  • General safety write-ups exist for 4 of 4.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Orally, the ingredients in this product are generally well tolerated. Cranberry and pumpkin products are well tolerated as food or supplement doses, though large amounts of cranberry juice can cause diarrhea and gastrointestinal upset.

Horsetail has limited clinical safety data; the most common side effects reported are abdominal bloating, increased bowel movements, and nausea. Long-term safety at supplement doses is not well established for tocotrienols, and crude horsetail can contain thiaminase, which may lead to thiamine deficiency with prolonged use — though Canadian products are required to be certified free of this.

For pregnancy, there is not enough safety data for horsetail or pumpkin seed concentrates, so they should be avoided unless your doctor approves. Tocotrienols should be avoided during pregnancy.

Cranberry in normal food amounts is likely fine, but concentrated supplements have not been well studied during pregnancy or breastfeeding — check with your provider before using.

Side effects, ingredient by ingredient Tocotrienols Pumpkin Horsetail Cranberry

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 4 of the 4 matched ingredients can interact with medications — Pumpkin, Horsetail, Cranberry, Tocotrienols.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications; lithium.
  • For scale: 936 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check with your doctor or pharmacist if you take any of these: nucleoside reverse transcriptase inhibitors (NRTIs) or efavirenz (HIV medications), blood thinners or antiplatelet drugs, antidiabetes drugs, diuretics, lithium, or medications affected by liver metabolism like atorvastatin or nifedipine. Horsetail and cranberry may change how these drugs work.

No interactions are documented for the ingredients we could not check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glancePartially disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

This product may be worth considering if you're dealing with urinary tract infections (cranberry is possibly effective) or prostate concerns (pumpkin seed extract is possibly effective). However, if you take any prescription medications — especially blood thinners, HIV drugs, diabetes medications, diuretics, or lithium — check your exact medications with the tool on this page before starting.

Talk it over with your doctor or pharmacist, particularly if you're pregnant, breastfeeding, or taking long-term medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 4 of 6 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 22, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Bladder Health, straight from the product label.

Brand Emerald Labs
Barcode (UPC) 743650003648
Net contents 60 Vegetable Cap(s)
Market status On market
Date entered into DSLD Feb 22, 2024
DSLD ID 302539
Product type Botanical With Nutrients
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Bladder Health by Emerald Labs, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
30
UPC/BARCODE
743650003648
IngredientAmount% DV
Tocotriene Complex50 mg--
Pumpkin seed extract100 mg--
Urox Blend840 mg--
Lindera aggregata0 NP--
Horsetail0 NP--
Cratevox0 NP--
PACran50 mg--

Other ingredients: Vegetable Capsule

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Urox is a proprietary blend of clinically-proven herbal plant ingredients combined with pumpkin seed extract and PACran, which may help to support muscle tone and ease the discomfort associated with overactive frequency and urgency in both men and women. 1. Schoendorfer et al. BMC-CAM, 2018.

Bladder Health for Men & Women with Urox Blend + PACran and Pumpkin Seed

Bladder Health for Men & Women with Urox Blend + PACran and Pumpkin Seed

With Urox With PACran Standardized Extract

General Statements

Emerald Labs is family owned and operated since our beginnings in 1996. We are committed to providing your family with additive-free formulas and superior nutrient forms in therapeutic amounts.

Doctor-Formulated

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent disease.

Brand IP Statement(s)

PACran is a Registered trademark of Decas Botanical Synergies Urox an Cratevox are trademarks of Seipel Group Pty Ltd. U.S. Patent No. 9,452,191. Canadian Patent Pending No. 2859462 Copyright 2021 Emerald Labs, Inc. Emerald Labs The Additive-Free Company

Formulation

Clinical Potency

Made with Non-GMO Ingredients No Magnesium Stearate Gluten-Free

Vegan Formula

This product is free of: Corn protein, milk, salt, yeast, soy, added sugar, wheat, artificial flavors and preservatives.

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested Use: Adults, take two (2) capsules daily with food or as directed by a health care practitioner.

Precautions

Keep out of reach of children.

Do not use if safety seal on cap or printed inner seal is missing or broken.

Consult a physician if pregnant, lactating, currently on prescription medication or diagnosed with a medical condition.

Storage

Store in a cool, dry place.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Bladder Health by Emerald Labs label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Bladder Health label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Bladder Health by Emerald Labs

These are the 6 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Tocotriene Complex

Interacts with
122 drugs
50 mg per serving

Tocotrienols are a less common form of vitamin E with strong antioxidant activity studied mostly for cholesterol, liver, and heart health. Early resea...

Tocotriene Complex monograph & interactions

Pumpkin seed extract

Interacts with
1 drug
100 mg per serving

Pumpkin is a nutritious squash, and its seeds and seed oil are the parts most often used as supplements, mainly for urinary and prostate symptoms. The...

Pumpkin seed extract monograph & interactions

Urox Blend

840 mg per serving
  • › Lindera aggregata
  • › Horsetail
  • › Cratevox

PACran

Interacts with
712 drugs
50 mg per serving Form: Cranberry Extract, Powder

Cranberry is best known for helping to prevent repeated urinary tract infections (UTIs) in some people, and the evidence here is moderate but mixed. I...

PACran monograph & interactions

Other (inactive) ingredients: Vegetable Capsule. These complete the product’s ingredient list but are not active constituents.

Interaction report

Bladder Health by Emerald Labs Drug Interactions

Want to check YOUR meds against Bladder Health?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
935Drugs
813 Moderate 122 Minor

Ingredients driving the most interactions

PACran 712
Horsetail 188
Tocotriene Complex 122
Pumpkin seed extract 1

Individual Drug Interactions

The ingredients in Bladder Health interact with 935 drugs. Click any drug to see the details.

4 of the 6 ingredients in Bladder Health interact with drugs. Each result below shows which ingredient is responsible. PACran Horsetail Tocotriene Complex Pumpkin seed extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Bladder Health with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

PACran6 drug types · 712 drugs

Atorvastatin (Lipitor)

Theoretically, cranberry might increase levels and adverse effects of atorvastatin.
In one case report, a patient taking atorvastatin experienced upper back pain, rhabdomyolysis, and abnormal liver function after drinking cranberry juice 16 ounces daily for 2 weeks. Theoretically, this may have been caused by inhibition of cytochrome P450 3A4 (CYP3A4) enzymes by cranberry juice, as atorvastatin is a CYP3A4 substrate. Creatinine kinase and liver enzymes normalized within 2 weeks of stopping cranberry juice. Patients taking atorvastatin should avoid large quantities of cranberry juice.

Likelihood Possible Evidence D
Cytochrome P450 3A4 (Cyp3A4) Substrates

Theoretically, cranberry might increase the levels and adverse effects of CYP3A4 substrates.
A case of upper back pain, rhabdomyolysis, and abnormal liver function has been reported for a patient taking atorvastatin, a CYP3A4 substrate, in combination with cranberry juice 16 ounces daily for 2 weeks. Creatinine kinase and liver enzymes normalized within 2 weeks of stopping cranberry juice. Also, animal research suggests that cranberry juice, administered intraduodenally 30 minutes prior to nifedipine, a CYP3A4 substrate, inhibits nifedipine metabolism and increases the area under the concentration-time curve by 1.6-fold compared to control.

Likelihood Possible Evidence D
Nifedipine (Procardia)

Theoretically, cranberry might increase the levels and adverse effects of nifedipine.
Animal research suggests that cranberry juice, administered intraduodenally 30 minutes prior to nifedipine treatment, inhibits nifedipine metabolism and increases the area under the concentration-time curve by 1.6-fold compared to control. This interaction has not been reported in humans.

Likelihood Possible Evidence D
Warfarin (Coumadin)

Theoretically, cranberry might increase the levels and adverse effects of warfarin. However, research is conflicting.
There is contradictory evidence about the effect of cranberry juice on warfarin. Case reports have linked cranberry juice consumption to increases in the international normalized ratio (INR) in patients taking warfarin, resulting in severe spontaneous bleeding and excessive postoperative bleeding. Daily consumption of cranberry sauce for one week has also been linked to an increase in INR in one case report. In a small study in healthy young males, taking a high dose of 3 grams of cranberry juice concentrate capsules, equivalent to 57 grams of fruit daily, for 2 weeks produced a 30% increase in the area under the INR-time curve after a single 25-mg dose of warfarin. However, 3 very small clinical studies in patients stabilized on warfarin reported that cranberry juice 250 mL once or twice daily for 7 days (27% cranberry juice or pure cranberry juice) or 240 mL once daily for 14 days does not significantly increase INR or affect plasma warfarin levels. The reasons for these discrepant findings are unclear. It is possible that the form and dose of cranberry may play a role, as cranberry extracts and juices contain different constituents. Additionally, an in vitro study evaluating 5 different cranberry juices found varying effects, with only a cranberry concentrate, and not diluted cranberry juices, inhibiting CYP2C9. However, this concentrate did not inhibit CYP2C9 activity in humans.

Likelihood Possible Evidence B
Cytochrome P450 2C9 (Cyp2C9) Substrates

Theoretically, cranberry might increase the levels and adverse effects of CYP2C9 substrates. However, research is conflicting.
There is contradictory evidence about the effect of cranberry on CYP2C9 enzymes. In vitro evidence suggests that flavonoids in cranberry inhibit CYP2C9 enzymes. However, clinical research shows that cranberry juice does not significantly affect the levels, metabolism, or elimination of the CYP2C9 substrates flurbiprofen or diclofenac. Also, in patients stabilized on warfarin, drinking cranberry juice 250 mL daily for 7 days does not significantly increase the anticoagulant activity of warfarin, a CYP2C9 substrate. Additional pharmacokinetic research shows that cranberry juice does not increase peak plasma concentrations or area under the concentration-time curve of warfarin.

Likelihood Unlikely Evidence B
Diclofenac (Voltaren, Others)

Theoretically, cranberry might modestly increase the levels and adverse effects of diclofenac.
In vitro evidence suggests that cranberry juice inhibits diclofenac metabolism by human liver microsomes. However, drinking cranberry juice does not seem to affect diclofenac metabolism in humans.

Likelihood Unlikely Evidence B
PACran full monograph & interactions

Horsetail5 drug types · 188 drugs

Antidiabetes Drugs

Theoretically, taking horsetail with antidiabetes drugs might increase the risk of hypoglycemia.
Equisetum myriochaetum has demonstrated hypoglycemic activity in clinical research. In an animal diabetic model, Equisetum giganteum had hypoglycemic effects. It is unclear whether other horsetail species have hypoglycemic effects.

Likelihood Possible Evidence D
Diuretic Drugs

Theoretically, taking horsetail with diuretic drugs might increase potassium loss and the risk of hypokalemia.
Laboratory research shows that various species of horsetail have diuretic properties. Due to its diuretic effects, there has been concern that taking horsetail along with potassium-depleting diuretics might increase the risk for hypokalemia. However, pharmacokinetic research in humans shows that taking horsetail 900 mg daily for 4 days does not affect urinary excretion of electrolytes, including potassium and sodium, despite having a diuretic effect similar to taking hydrochlorothiazide 25 mg daily. It is unclear if taking horsetail for a longer duration would affect electrolyte levels. Until more is known, use with caution.

Likelihood Possible Evidence D
Efavirenz (Sustiva)

Theoretically, horsetail might decrease the levels and clinical effects of efavirenz.
In two case reports, patients were found to have detectable viral loads when taking horsetail-containing supplements along with an antiretroviral regimen that included efavirenz. In one case, the antiretroviral regimen included zidovudine, lamivudine, and efavirenz; in the other case, the regimen consisted of emtricitabine, tenofovir disoproxil fumarate, and efavirenz. One month after discontinuing horsetail, the viral loads became undetectable in both cases. The exact mechanism of this interaction is unknown. It is also unclear if this interaction is specific to efavirenz or if it is related to various components of antiretroviral therapy.

Likelihood Possible Evidence D
Lithium

Theoretically, horsetail might increase the levels and adverse effects of lithium.
Animal research suggests that horsetail has diuretic properties. Theoretically, due to these potential diuretic effects, horsetail might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.

Likelihood Possible Evidence D
Nucleoside Reverse Transcriptase Inhibitors (Nrtis)

Theoretically, horsetail might decrease the levels and clinical effects of NRTIs.
In two case reports, patients were found to have detectable viral loads when taking horsetail-containing supplements along with an antiretroviral therapy. In one case, the antiretroviral regimen included zidovudine, lamivudine, and efavirenz; in the other case, the regimen consisted of emtricitabine, tenofovir disoproxil fumarate, and efavirenz. One month after discontinuing the supplement, the viral loads became undetectable in both cases. The exact mechanism of these interactions is unknown. It is also unclear if these interactions are specific to NRTIs or if they are related to various components of antiretroviral therapy.

Likelihood Possible Evidence D
Horsetail full monograph & interactions

Tocotriene Complex1 drug type · 122 drugs

Anticoagulant/Antiplatelet Drugs

Concomitant use of tocotrienols with anticoagulant or antiplatelet agents might increase the risk of bleeding. However, this has not been reported in humans.
Taking tocotrienols orally inhibits experimentally-induced platelet aggregation in humans. Theoretically tocotrienols might increase the risk of bleeding if taken with antiplatelet or anticoagulant drugs. However, tocotrienols 400-800 mg daily have been used with aspirin and/or clopidogrel for 1 year with no clear cumulative antiplatelet effects and no reports of bleeding.

Likelihood Unlikely Evidence B
Tocotriene Complex full monograph & interactions

Pumpkin seed extract1 drug type · 1 drug

Lithium

Pumpkin might reduce excretion and increase levels of lithium.
Pumpkin is thought to have diuretic properties. Theoretically, this might reduce excretion and increase levels of lithium. The dose of lithium might need to be decreased.

Likelihood Probable Evidence D
Pumpkin seed extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Bladder Health, from the product label.

Emerald Labs

See all Emerald Labs products
Name
Emerald Labs
Street Address
20600 Belshaw Ave.
City
Carson
State
CA
ZipCode
90746
Phone Number
800-436-4366
Web Address
www.emeraldlabs.com
Pharmacist Counseling Corner

Bladder Health by Emerald Labs: Common Questions

Does Bladder Health by Emerald Labs interact with any medications?
Yes. Based on its ingredients, Bladder Health has a known interaction with 935 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Bladder Health contains 6 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Will this interact with my blood thinner?
Cranberry in this product may interact with warfarin (a blood thinner) at Moderate severity, and tocotriene may interact with anticoagulants and antiplatelets at Minor severity. Check your specific medication with the search tool on this page, then talk to your doctor or pharmacist before starting.
Is cranberry in this product safe during pregnancy?
Cranberry in normal food amounts is likely fine during pregnancy, but concentrated supplement doses — like what's in this product — have not been well studied. Check with your doctor or pharmacist before using during pregnancy.
Does this really help with UTIs?
The cranberry ingredient (PACran) is possibly effective for urinary tract infections based on the data we hold. However, cranberry is not a substitute for medical treatment — if you have a UTI, see your doctor.
Can I take this long-term?
Horsetail should be used short-term by healthy adults; long-term safety is not well established. Long-term safety of tocotrienols at supplement doses is also not well established. Talk to your doctor about how long to take this product.
What are the most common side effects?
From cranberry and pumpkin seed, you might experience mild gastrointestinal discomfort, diarrhea, or nausea. Horsetail may cause abdominal bloating and increased bowel movements. These are generally mild and well tolerated.
Is this safe while breastfeeding?
Cranberry in normal food amounts is likely fine, but safety of concentrated supplements while breastfeeding is not well studied. Horsetail should be avoided while breastfeeding. Talk with your doctor or pharmacist before using.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Bladder Health label
Go deeper

The Full Monographs Behind Bladder Health’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Tocotrienols

Interacts with 122 drugs

Tocotrienols are a less common form of vitamin E with strong antioxidant activity studied mostly for cholesterol, liver, and heart health. Early research is interesting but far from conclusi...

Read the full Tocotrienols monograph → Herb & supplement monograph

Pumpkin

Interacts with 1 drug

Pumpkin is a nutritious squash, and its seeds and seed oil are the parts most often used as supplements, mainly for urinary and prostate symptoms. The evidence for these uses is limited and...

Read the full Pumpkin monograph → Herb & supplement monograph

Horsetail

Interacts with 188 drugs

Horsetail is a traditional herb most often used as a mild diuretic and for hair, nail, and bone support, but high-quality human evidence is limited. It can cause thiamine (vitamin B1) loss w...

Read the full Horsetail monograph → Herb & supplement monograph

Cranberry

Interacts with 712 drugs

Cranberry is best known for helping to prevent repeated urinary tract infections (UTIs) in some people, and the evidence here is moderate but mixed. It is not a reliable treatment for an act...

Read the full Cranberry monograph →
Sources

Sources & How We Checked

Bladder Health's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 56 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Tocotrienols 4 references
  1. Mensink RP, van Houwelingen AC, Kromhout D, Hornstra G. A vitamin E concentrate rich in tocotrienols had no effect on serum lipids, lipoproteins, or platelet function in men with mildly elevated serum lipid concentrations. Am J Clin Nutr 1999;69:213-9. PubMed
  2. Baumann LS, Spencer JS. The effects of topical vitamin E on the cosmetic appearance of scars. Dermatol Surg 1999;25:311-5. PubMed
  3. Khoo TL, Halim AS, Zakaria Z, Mat Saad AZ, Wu LY, Lau HY. A prospective, randomised, double-blinded trial to study the efficacy of topical tocotrienol in the prevention of hypertrophic scars. J Plast Reconstr Aesthet Surg. 2011 Jun;64(6):e137-45. Epub 201 PubMed
  4. Slivka A, Rink C, Paoletto D, Sen CK. Platelet function in stroke/transient ischemic attack patients treated with tocotrienol. FASEB J. 2020;34(9):11838-11843. PubMed

See these in context on the Tocotrienols monograph →

Pumpkin 5 references
  1. Marks L, Partin AW, Epstein JI, et al. Effects of a saw palmetto herbal blend in men with symptomatic benign prostatic hyperplasia. J Urol 2000;163:1451-6. DOI
  2. Cho YH, Lee SY, Jeong DW, et al. Effect of pumpkin seed oil on hair growth in men with androgenetic alopecia: a randomized, double-blind, placebo-controlled trial. Evid Based Complement Alternat Med 2014;2014:549721. PubMed
  3. Vahlensieck W, Theurer C, Pfitzer E, Patz B, Banik N, Engelmann U. Effects of pumpkin seed in men with lower urinary tract symptoms due to benign prostatic hyperplasia in the one-year, randomized, placebo-controlled GRANU study. Urol Int 2015;94(3):286-95 PubMed
  4. Assouly P. Hair loss associated with cucurbit poisoning. JAMA Dermatol. 2018 May 1;154(5):617-618. PubMed
  5. Gawryjolek J, Ludwig H, Zbikowska-Götz M, Bartuzi Z, Krogulska A. Anaphylaxis after consumption of pumpkin seeds in a 2-y-old child tolerant to its pulp: A case study. Nutrition 2021;89:111272. PubMed

See these in context on the Pumpkin monograph →

Horsetail 14 references
  1. Sudan BJ. Seborrhoeic dermatitis induced by nicotine of horsetails (Equisetum arvense L.). Contact Dermatitis 1985;13:201-2.
  2. Perez Gutierrez RM, Laguna GY, Walkowski A. Diuretic activity of Mexican equisetum. J Ethnopharmacol 1985;14:269-72. PubMed
  3. Lemus I, Garcia R, Erazo S, et al. Diuretic activity of an Equisetum bogotense tea (Platero herb): evaluation in healthy volunteers. J Ethnopharmacol 1996;54:55-8. PubMed
  4. Revilla MC, Andrade-Cetto A, Islas S, Wiedenfeld H. Hypoglycemic effect of Equisetum myriochaetum aerial parts on type 2 diabetic patients. J Ethnopharmacol 2002;81:117-20. PubMed
  5. Tiktinskii, O. L. and Bablumian, I. A. [Therapeutic action of Java tea and field horsetail in uric acid diathesis]. Urol.Nefrol.(Mosk) 1983;3(1):47-50.
  6. Henderson JA, Evans EV, and McIntosh RA. The antithiamine action of Equisetum. J Amer Vet Med Assoc 1952;120:375-378.
  7. Carneiro DM, Freire RC, Honório TC, Zoghaib I, Cardoso FF, Tresvenzol LM, de Paula JR, Sousa AL, Jardim PC, da Cunha LC. Randomized, Double-Blind Clinical Trial to Assess the Acute Diuretic Effect of Equisetum arvense (Field Horsetail) in Healthy Voluntee
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See these in context on the Horsetail monograph →

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See these in context on the Cranberry monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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