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Dietary supplement

Broccoli/Cruciferous Max-V Extract Ingredients & Drug Interactions

by Douglas Laboratories

Broccoli/Cruciferous Max-V Extract label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Broccoli/Cruciferous Max-V Extract against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Broccoli/Cruciferous Max-V Extract is a dietary supplement by Douglas Laboratories with 4 active ingredients. Its ingredients are commonly taken for general nutrition and a low-carb vegetable, source of vitamin c and fiber, antioxidant support.Based on those ingredients, 273 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Broccoli, Cauliflower, Radish. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Broccoli/Cruciferous Max-V Extract by Douglas Laboratories

Ask about any prescription or over-the-counter medication and we check it for interactions with Broccoli/Cruciferous Max-V Extract by Douglas Laboratories — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Broccoli/Cruciferous Max-V Extract by Douglas Laboratories

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 16, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 4 active ingredients.
  • “Proprietary Herbal Blend” is a proprietary blend — the label gives one combined amount (100 mg) without saying how much of each component you get.
  • “Proprietary Blend Herbal Extract” is a proprietary blend — the label gives one combined amount (250 mg) without saying how much of each component you get.

This product contains 4 active ingredients: broccoli, kale, radish, and cauliflower — all cruciferous or related vegetables in concentrated extract form. Broccoli and cauliflower contain glucosinolates, compounds that can influence how your liver processes drugs.

Kale and radish round out the blend. The capsules also contain cellulose and vegetable stearate as inactive ingredients (binders and fillers).

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded its ingredients' overall clinical evidence instead.

Moderate

Some clinical evidence supports its ingredients for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredients' overall clinical evidence instead.
  • On file: Colorectal cancer — rated "Possibly Effective" (Broccoli) (Natural Medicines).

The evidence for what this product actually does is sparse. Broccoli is rated possibly effective for colorectal cancer, but for bladder cancer, breast cancer, fibromyalgia, and gastric cancer, there isn't enough reliable evidence to rate it.

Kale, radish, and cauliflower all have insufficient evidence for the conditions they've been studied in — including bladder cancer, breast cancer, inflammatory bowel disease, menopausal symptoms, biliary disorders, diabetes, lung cancer, and prostate cancer. In short, we don't have solid proof this supplement works for most claimed uses.

The evidence, ingredient by ingredient Cauliflower Broccoli Kale Radish

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 2 of the 4 matched ingredients.
  • Pregnancy & breastfeeding safety ratings cover 4 of 4.
  • General safety write-ups exist for 4 of 4.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Broccoli, kale, radish, and cauliflower are all common foods and are rated likely safe in pregnancy and lactation when eaten as food. However, concentrated supplement forms — which is what you have here — are much less studied.

The safety data advises caution with concentrated broccoli, radish, and cauliflower extracts unless your doctor approves. Adverse effects reported with concentrated extracts include loose stools, diarrhea, abdominal pain, and cramping, especially at higher doses.

Radish can cause allergic reactions and throat tightness in sensitive people, and large amounts may irritate your stomach.

Side effects, ingredient by ingredient Cauliflower Broccoli Kale Radish

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 3 of the 4 matched ingredients can interact with medications — Radish, Broccoli, Cauliflower.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 273 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, double-check any medications metabolized by CYP1A2 (Moderate severity) — a large group that includes some antidepressants, certain heart medications, and others. Also check CYP2A6 substrates (Moderate severity), another set of drugs that this product can make less effective.

If you take antidiabetes medications, be aware radish may increase your risk of low blood sugar. Use the interaction tool below with your specific drug names.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

This is a cruciferous vegetable extract that can speed up your liver's processing of certain medications — potentially making them less effective. If you take any prescription drugs metabolized by the liver, especially antidiabetes medications, you need to check with your doctor or pharmacist before starting this product.

Concentrated forms of these vegetables aren't as well studied as the foods themselves, and the evidence that this supplement actually works for its claimed uses is weak or missing.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 4 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 25, 2012.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Broccoli/Cruciferous Max-V Extract, straight from the product label.

Brand Douglas Laboratories
Barcode (UPC) 310539001134
Net contents 60 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Jun 25, 2012
DSLD ID 9555
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Broccoli/Cruciferous Max-V Extract by Douglas Laboratories, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Vegetarian Capsule(s)
Maximum serving Sizes:
1 Vegetarian Capsule(s)
Servings per container
60
UPC/BARCODE
310539001134
IngredientAmount% DV
Broccoli0 NP--
Kale0 NP--
Proprietary Herbal Blend100 mg--
Proprietary Blend Herbal Extract250 mg--
Radish0 NP--
Cauliflower0 NP--

Other ingredients: Cellulose, Vegetable Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Broccoli (Brassica oleracea Botrytis cymosa), Kale (Bras-sica oleracea var. acephala), and Radish (Raphanus sativus) are rich in isothiocyanates, especially sulforaphane; broccoli contains indoles, notably indole-3-carbinol. This extract is standardized at 0.04% sulforaphane.

Suggested/Recommended/Usage/Directions

Suggested Usage: As a dietary supplement, adults take 1 capsule daily between meals or as advised by your healthcare professional.

Precautions

Stop use and consult your health care professional if allergic reactions occur.

Note: If pregnant or nursing consult your health care professional before using this product.

KEEP OUT OF REACH OF CHILDREN.

Tamper resistant package, do not use if outer seal is missing.

Storage

For optimal storage conditions, store in a cool, dry place. (59(0)-77(0)F/15(0)-25(0)C) (35-65% relative humidity)

General

Formula #77308

FDA Statement of Identity

Standardized Herbal Extract Supplement

Formula

0.04% sulforaphane

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Broccoli/Cruciferous Max-V Extract by Douglas Laboratories label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Broccoli/Cruciferous Max-V Extract label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Broccoli/Cruciferous Max-V Extract by Douglas Laboratories

These are the 4 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Vegetarian Capsule(s) Dosage formCapsule Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Proprietary Herbal Blend

100 mg per serving

Proprietary Blend Herbal Extract

250 mg per serving Form: Sulforaphane

Other (inactive) ingredients: Cellulose, Vegetable Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Broccoli/Cruciferous Max-V Extract by Douglas Laboratories Drug Interactions

Want to check YOUR meds against Broccoli/Cruciferous Max-V Extract?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
273Drugs
273 Moderate

Ingredients driving the most interactions

Broccoli 187
Cauliflower 186
Radish 86

Individual Drug Interactions

The ingredients in Broccoli/Cruciferous Max-V Extract interact with 273 drugs. Click any drug to see the details.

3 of the 4 ingredients in Broccoli/Cruciferous Max-V Extract interact with drugs. Each result below shows which ingredient is responsible. Broccoli Cauliflower Radish

Each ingredient & the kinds of drugs it affects

For each ingredient in Broccoli/Cruciferous Max-V Extract with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.

Broccoli2 drug types · 187 drugs

Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, broccoli might reduce the levels and effects of drugs metabolized by CYP1A2.
Pharmacokinetic research in humans shows that eating 500 grams of fresh broccoli daily for 6-12 days can increase CYP1A2 activity by 10% to 200%. Induction of CYP1A2 activity by broccoli is attributed to its glucosinolate constituents.

Likelihood Possible Evidence B
Cytochrome P450 2A6 (Cyp2A6) Substrates

Theoretically, broccoli might reduce the levels and effects of drugs metabolized by CYP2A6.
Pharmacokinetic research in humans shows that eating 500 grams of broccoli daily for 6 days increases CYP2A6 activity by 135% to 550%. Induction of CYP2A6 activity is attributed to its glucosinolate constituents.

Likelihood Possible Evidence B
Broccoli full monograph & interactions

Cauliflower1 drug type · 186 drugs

Cytochrome P450 1A2 (Cyp1A2) Substrates

Preliminary clinical evidence suggests that eating cruciferous vegetables, including broccoli, cauliflower, daikon radish sprouts, and cabbage, can increase cytochrome P450 1A2 (CYP1A2) activity by 14% to 27%. Theoretically, cauliflower might increase the clearance and decrease the effects of drugs metabolized by CYP1A2. Some drugs metabolized by CYP1A2 include clozapine (Clozaril), cyclobenzaprine (Flexeril), fluvoxamine (Luvox), haloperidol (Haldol), imipramine (Tofranil), mexiletine (Mexitil), olanzapine (Zyprexa), pentazocine (Talwin), propranolol (Inderal), tacrine (Cognex), theophylline, zileuton (Zyflo), zolmitriptan (Zomig), and others.

Likelihood Possible Evidence B
Cauliflower full monograph & interactions

Radish1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, radish might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Animal research shows that radish extract, juice, and sprouts can reduce glucose levels. Animal research also shows that radish root juice 300 mg/kg reduces fasting and postprandial blood glucose in a rat model of diabetes, with effects similar to glibenclamide.

Likelihood Possible Evidence D
Radish full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Broccoli/Cruciferous Max-V Extract, from the product label.

Douglas Laboratories

See all Douglas Laboratories products
Name
Douglas Laboratories
Street Address
600 Boyce Road
City
Pittsburgh
State
PA
ZipCode
15205
Phone Number
1.800.245.4440
Web Address
www.douglaslabs.com
Pharmacist Counseling Corner

Broccoli/Cruciferous Max-V Extract by Douglas Laboratories: Common Questions

Does Broccoli/Cruciferous Max-V Extract by Douglas Laboratories interact with any medications?
Yes. Based on its ingredients, Broccoli/Cruciferous Max-V Extract has a known interaction with 273 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Broccoli/Cruciferous Max-V Extract contains 4 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does this work to prevent cancer?
Broccoli is rated possibly effective for colorectal cancer based on available evidence, but for bladder, breast, gastric, lung, and prostate cancers, there isn't enough reliable research to say whether it helps. The other ingredients don't have established evidence for cancer prevention either.
Is it safe to take while pregnant or breastfeeding?
Broccoli and kale are rated likely safe in pregnancy and lactation when eaten as food. However, this is a concentrated extract, which is less studied in pregnancy and breastfeeding, so talk with your doctor about whether concentrated supplement forms are right for you.
What side effects might I notice?
Loose stools, diarrhea, abdominal pain, and cramping have been reported with broccoli and radish extracts, particularly at higher doses. Radish can rarely cause allergic reactions like throat tightness. Large amounts may also cause stomach irritation.
Can I take this if I have diabetes and use blood sugar medication?
Radish in this product may lower blood glucose and increase your risk of hypoglycemia when combined with antidiabetes drugs. Check with your doctor or pharmacist before taking this product if you use diabetes medication.
Will this affect my prescription medications?
Yes — broccoli and cauliflower can speed up your liver's processing of certain medications, making them less effective. Use the interaction checker on this page with your specific drug names, and confirm with your doctor or pharmacist before starting.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Broccoli/Cruciferous Max-V Extract label
Go deeper

The Full Monographs Behind Broccoli/Cruciferous Max-V Extract’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Cauliflower

Interacts with 186 drugs

Cauliflower is a nutritious cruciferous vegetable that provides vitamin C, fiber, and plant compounds called glucosinolates. As a food it is healthy and safe for most people, but there is no...

Read the full Cauliflower monograph → Herb & supplement monograph

Broccoli

Interacts with 187 drugs

Broccoli is a nutritious cruciferous vegetable rich in fiber, vitamins, and plant compounds like sulforaphane that have drawn scientific interest for health benefits. Eating broccoli as food...

Read the full Broccoli monograph → Herb & supplement monograph

Kale

Kale is a nutrient-dense leafy green vegetable that is rich in vitamins, minerals, fiber, and antioxidants. Eaten as a normal food it is very healthy for most people, but it is a whole food...

Read the full Kale monograph → Herb & supplement monograph

Radish

Interacts with 86 drugs

Radish is a common edible root vegetable that is nutritious and generally safe to eat as food. Some people use radish (especially black radish) and its extracts for digestion and liver suppo...

Read the full Radish monograph →
Sources

Sources & How We Checked

Broccoli/Cruciferous Max-V Extract's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 21 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Broccoli 5 references
  1. Kristal AR, Lampe JW. Brassica vegetables and prostate cancer risk: a review of the epidemiological evidence. Nutr Cancer 2002;42:1-9. PubMed
  2. Chakrabarti A, Prais L, Foulds IS. Allergic contact dermatitis to broccoli. Br J Dermatol 2003;148:172-3. PubMed
  3. Hakooz, N. and Hamdan, I. Effects of dietary broccoli on human in vivo caffeine metabolism: a pilot study on a group of Jordanian volunteers. Curr Drug Metab 2007;8(1):9-15. PubMed
  4. Kall MA, Vang O, Clausen J. Effects of dietary broccoli on human drug metabolising activity. Cancer Lett. 1997;114(1-2):169-70. PubMed
  5. Bauman JE, Hsu CH, Centuori S, et al. Randomized Crossover Trial Evaluating Detoxification of Tobacco Carcinogens by Broccoli Seed and Sprout Extract in Current Smokers. Cancers (Basel). 2022;14(9):2129. Published 2022 Apr 24. PubMed

See these in context on the Broccoli monograph →

Kale 2 references
  1. Vitamin K - Health Professional Fact Sheet — NIH Office of Dietary Supplements Source
  2. Lutein and Zeaxanthin — NIH Office of Dietary Supplements Source

See these in context on the Kale monograph →

Radish 5 references
  1. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  2. Damiani E, Aloia AM, Priore MG, Nardulli S, Ferrannini A. Generalized urticaria after ingestion of Raphanus sativus. Ann Allergy Asthma Immunol. 2011 Feb;106(2):168. PubMed
  3. Evans M, Paterson E, Barnes DM. An open label pilot study to evaluate the efficacy of Spanish black radish on the induction of phase I and phase II enzymes in healthy male subjects. BMC Complement Altern Med. 2014 Dec 9;14:475. PubMed
  4. Banihani SA. Radish (Raphanus sativus) and diabetes. Nutrients. 2017;9(9). pii: E1014. PubMed
  5. Shukla S, Chatterji S, Mehta S, Rai PK, Singh RK, Yadav DK, Watal G. Antidiabetic effect of Raphanus sativus root juice. Pharm Biol. 2011 Jan;49(1):32-7.

See these in context on the Radish monograph →

Cauliflower 9 references
  1. Joshipura KJ, Ascherio A, Manson JE, et al. Fruit and vegetable intake in relation to risk of ischemic stroke. JAMA 1999;282:1233-39. PubMed
  2. Zhao H, Lin J, Grossman HB, et al. Dietary isothiocyanates, GSTM1, GSTT1, NAT2 polymorphisms and bladder cancer risk. Int J Cancer 2007;120:2208-13.
  3. Cohen, J. H., Kristal, A. R., and Stanford, J. L. Fruit and vegetable intakes and prostate cancer risk. J Natl.Cancer Inst. 1-5-2000;92(1):61-68. PubMed
  4. Michaud DS, Spiegelman D, Clinton SK, et al. Fruit and vegetable intake and incidence of bladder cancer in a male prospective cohort. J Natl Cancer Inst 1999;91(7):605-13. PubMed
  5. Feskanich D, Ziegler RG, Michaud DS, et al. Prospective study of fruit and vegetable consumption and risk of lung cancer among men and women. J Natl Cancer Inst 2000;92(22):1812-23. PubMed
  6. Chang ET, Smedby KE, Zhang SM, et al. Dietary factors and risk of non-Hodgkin lymphoma in men and women. Cancer Epidemiol Biomarkers Prev 2005;14(2):512-20. PubMed
  7. Liu S, Serdula M, Janket SJ, et al. A prospective study of fruit and vegetable intake and the risk of type 2 diabetes in women. Diabetes Care 2004;27(12):2993-6. PubMed
  8. Gaudet MM, Britton JA, Kabat GC, et al. Fruits, vegetables, and micronutrients in relation to breast cancer modified by menopause and hormone receptor status. Cancer Epidemiol Biomarkers Prev 2004;13(9):1485-94. DOI
  9. Peterson S, Schwarz Y, Li SS, et al. CYP1A2, GSTM1, and GSTT1 polymorphisms and diet effects on CYP1A2 activity in a crossover feeding trial. Cancer Epidemiol Biomarkers Prev 2009;18(11):3118-25.

See these in context on the Cauliflower monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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