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Dietary supplement

Broccoli Extract Powder Ingredients & Drug Interactions

by PureBulk.com

Broccoli Extract Powder label
See full label image
Powder Category: Botanical
Most serious interaction: Minor
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Broccoli Extract Powder against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Minor

Broccoli Extract Powder is a dietary supplement by PureBulk.com with 1 active ingredient. Its ingredients are commonly taken for antioxidant support, detoxification support, general heart health.Based on those ingredients, 187 medications have a known interaction with it, the most serious rated minor. The ingredients most likely to interact are Broccoli sprout extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Broccoli Extract Powder by PureBulk.com

Ask about any prescription or over-the-counter medication and we check it for interactions with Broccoli Extract Powder by PureBulk.com — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Broccoli Extract Powder by PureBulk.com

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 16, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: broccoli sprout extract. Broccoli sprout extract is a concentrated form of compounds found in young broccoli plants, specifically the seedlings that sprout in the first few days of growth.

The product also contains maltodextrin, which is an inactive ingredient used as a filler to improve handling and texture of the powder.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Broccoli Sprout product and its label doesn't state a use — see Broccoli Sprout's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence isn't established for any of the conditions listed on broccoli sprout extract — including hay fever, asthma, prostate cancer, liver disease, and Helicobacter pylori infection. The data we hold shows insufficient reliable evidence to rate it for any of these uses.

That doesn't mean it doesn't work; it means the research so far isn't solid enough to say one way or the other.

The evidence, ingredient by ingredient Broccoli Sprout

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Broccoli sprout extract is generally well tolerated when eaten as food, but concentrated supplements are less studied and quality varies — concentrated forms haven't been as thoroughly researched as the whole vegetable. At higher doses, loose stools, diarrhea, abdominal pain, and cramping have been reported.

Raw broccoli sprouts that aren't grown properly can carry bacteria like Listeria, Salmonella, or E. coli O157:H7; cooking eliminates this risk. For pregnancy, the safety data shows it's likely safe.

For breastfeeding, the safety data shows it's possibly unsafe — there isn't enough information to know either way, so talk with your doctor or pharmacist before using this supplement while breastfeeding.

Side effects, ingredient by ingredient Broccoli Sprout

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Broccoli Sprout.
  • The most serious interaction on file is rated Minor.
  • For scale: 187 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take any medications broken down by CYP1A2 or CYP2A6 enzymes in your liver, double-check with your doctor or pharmacist before adding this supplement. Both interactions are Minor in severity, but they can reduce medication levels.

The interaction checker on this page can help you identify your specific drugs.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Only minor medication interactions are documented, and safety information is well characterized.

Broccoli sprout extract may be worth trying if you're interested in plant-based nutrition, but the evidence for specific health claims isn't solid yet. The main caution is that it can speed up how your liver clears certain medications, potentially making them less effective.

Before you start, check your exact medications with your doctor or pharmacist — especially if you take any drug that depends on liver enzymes to work.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 25, 2013.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Broccoli Extract Powder, straight from the product label.

Brand PureBulk.com
Net contents 250 g; 8.82 oz.
Market status On market
Date entered into DSLD Jun 25, 2013
DSLD ID 23036
Product type Botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Broccoli Extract Powder by PureBulk.com, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
500 mg
Maximum serving Sizes:
500 mg
Servings per container
500
IngredientAmount% DV
Broccoli sprout extract500 mg--

Other ingredients: Maltodextrin

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions

Keep out of reach of children.

Warning: This product is not intended for use by those with a serious medical condition or pregnant or lactating women.

Consult with your physician before use.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

General Statements

Derived from Brassica Oleracea sprouts (10:1)

US Standard Measuring Spoons Spoon Size (level) milligrams 1/16 teaspoon 228 1/8 teaspoon 456 1/4 teaspoon 912

Storage

Storage: Keep dry, cool & dark

Formulation

Free of: soy, dairy, yeast and gluten.

Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, take 500 mg (1/8 tsp) daily, or as directed by physician.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Broccoli Extract Powder by PureBulk.com label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Broccoli Extract Powder label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Broccoli Extract Powder by PureBulk.com

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size500 mg Dosage formPowder Servings per container500 Amounts shown are per serving.

Broccoli sprout extract

Interacts with
187 drugs
500 mg per serving

Broccoli sprouts are young broccoli seedlings rich in a compound called sulforaphane, which is being studied for antioxidant, anti-inflammatory, and d...

Broccoli sprout extract monograph & interactions

Other (inactive) ingredients: Maltodextrin. These complete the product’s ingredient list but are not active constituents.

Interaction report

Broccoli Extract Powder by PureBulk.com Drug Interactions

Want to check YOUR meds against Broccoli Extract Powder?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
187Drugs
187 Minor

Ingredients driving the most interactions

Broccoli sprout extract 187

Individual Drug Interactions

The ingredients in Broccoli Extract Powder interact with 187 drugs. Click any drug to see the details.

1 of the 1 ingredient in Broccoli Extract Powder interact with drugs. Each result below shows which ingredient is responsible. Broccoli sprout extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Broccoli Extract Powder with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Broccoli sprout extract2 drug types · 187 drugs

Cytochrome P450 1A2 (Cyp1A2) Substrates

Theoretically, broccoli sprout might reduce levels and effects of drugs metabolized by CYP1A2.
Animal research shows that broccoli sprout extract can increase CYP1A2 gene expression. Also, pharmacokinetic research in humans shows that eating 500 grams of fresh broccoli daily for 6-12 days can increase CYP1A2 activity by 10% to 200%. Induction of CYP1A2 activity by broccoli is attributed to glucosinolate constituents, which are also found in broccoli sprout.

Likelihood Possible Evidence D
Cytochrome P450 2A6 (Cyp2A6) Substrates

Theoretically, broccoli sprout might reduce levels and effects of drugs metabolized by CYP2A6.
Pharmacokinetic research in humans shows that eating broccoli 500 grams daily for 6 days increases CYP2A6 activity by 135% to 550%. Induction of CYP2A6 is attributed to glucosinolate constituents, which are also found in broccoli sprout.

Likelihood Possible Evidence D
Broccoli sprout extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Broccoli Extract Powder, from the product label.

PureBulk.com

See all PureBulk.com products
Name
PureBulk.com
City
Roseburg
State
OR
ZipCode
97471
Phone Number
(541) 679-1500
Web Address
PureBulk.com
Pharmacist Counseling Corner

Broccoli Extract Powder by PureBulk.com: Common Questions

Does Broccoli Extract Powder by PureBulk.com interact with any medications?
Yes. Based on its ingredients, Broccoli Extract Powder has a known interaction with 187 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Broccoli Extract Powder contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
Broccoli sprout extract is likely safe during pregnancy. For breastfeeding, there isn't enough data to say either way — talk with your doctor or pharmacist for personalized advice before using it while nursing.
What side effects might I get from this?
At higher doses, loose stools, diarrhea, belly pain, and cramping have been reported. If you use raw sprouts that haven't been properly grown, there's a small risk of food-borne illness from bacteria, but cooking the sprouts eliminates that risk.
Does broccoli sprout extract actually work for any conditions?
The research so far isn't reliable enough to say it works for hay fever, asthma, prostate cancer, liver disease, or H. pylori infection. The evidence is insufficient to rate it for these uses.
Why should I worry about this speeding up my liver?
When this supplement speeds up how your liver breaks down certain medications, those drugs may not stay in your system long enough to work well. If you take a medication that depends on one of these liver pathways, the effect could be meaningful.
Is this powder safe as a food versus as a supplement?
Broccoli sprouts as food are likely fine, but concentrated supplements like this one are less well studied and quality varies. Unless your doctor approves, concentrated supplements are best avoided.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Broccoli Extract Powder is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Broccoli Extract Powder label
Go deeper

The Full Monographs Behind Broccoli Extract Powder’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Broccoli Sprout

Interacts with 187 drugs

Broccoli sprouts are young broccoli seedlings rich in a compound called sulforaphane, which is being studied for antioxidant, anti-inflammatory, and detoxification effects. Early research is...

Read the full Broccoli Sprout monograph →
Sources

Sources & How We Checked

Broccoli Extract Powder's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 8 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Broccoli Sprout 8 references
  1. Hakooz, N. and Hamdan, I. Effects of dietary broccoli on human in vivo caffeine metabolism: a pilot study on a group of Jordanian volunteers. Curr Drug Metab 2007;8(1):9-15. PubMed
  2. Pezdirc KB, Hure AJ, Blumfield ML, Collins CE. Listeria monocytogenes and diet during pregnancy; balancing nutrient intake adequacy v. adverse pregnancy outcomes. Public Health Nutr 2012;15(12):2202-9.
  3. Gorski L, Flaherty D, Duhe JM. Comparison of the stress response of Listeria monocytogenes strains with sprout colonization. J Food Prot 2008;71(8):1556-1562. PubMed
  4. Fahey JW, Ourisson PJ, Degnan FH. Pathogen detection, testing, and control in fresh broccoli sprouts. Nutr J 2006;5:13. PubMed
  5. Rajkowski KT, Boyd G, Thayer DW. Irradiation D-values for Escherichia coli O157:H7 and Salmonella sp. on inoculated broccoli seeds and effects of irradiation on broccoli sprout keeping quality and seed viability. J Food Prot 2003;66(5):760-766. PubMed
  6. Yoshida K, Ushida Y, Ishijima T, et al. Broccoli sprout extract induces detoxification-related gene expression and attenuates acute liver injury. World J Gastroenterol. 2015;21(35):10091-103. PubMed
  7. Kall MA, Vang O, Clausen J. Effects of dietary broccoli on human drug metabolising activity. Cancer Lett. 1997;114(1-2):169-70. PubMed
  8. Bauman JE, Hsu CH, Centuori S, et al. Randomized Crossover Trial Evaluating Detoxification of Tobacco Carcinogens by Broccoli Seed and Sprout Extract in Current Smokers. Cancers (Basel). 2022;14(9):2129. Published 2022 Apr 24. PubMed

See these in context on the Broccoli Sprout monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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