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Dietary supplement

Inositol (Vitamin B8) Ingredients & Drug Interactions

by PureBulk.com

Inositol (Vitamin B8) label
See full label image
Powder Category: Non-nutrient/non-botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Inositol (Vitamin B8) against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Inositol (Vitamin B8) is a dietary supplement by PureBulk.com with 1 active ingredient. Its ingredients are commonly taken for polycystic ovary syndrome (pcos), anxiety and panic, depression and mood.Based on those ingredients, 86 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Inositol. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Inositol (Vitamin B8) by PureBulk.com

Ask about any prescription or over-the-counter medication and we check it for interactions with Inositol (Vitamin B8) by PureBulk.com — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Inositol (Vitamin B8) by PureBulk.com

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Aug 6, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains 1 active ingredient: inositol, a naturally occurring compound that plays a role in cell signaling and insulin sensitivity. The product comes as a powder with no other inactive ingredients listed.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Inositol's overall clinical evidence instead.

Moderate

Some clinical evidence supports Inositol for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Polycystic ovary syndrome (PCOS) — rated "Possibly Effective" (Natural Medicines).
  • On file: Preterm labor — rated "Possibly Effective" (Natural Medicines).
  • On file: Metabolic syndrome — rated "Possibly Effective" (Natural Medicines).

Inositol is possibly effective for polycystic ovary syndrome (PCOS) and metabolic syndrome, with some evidence it may help reduce the risk of preterm labor. The evidence is weaker for anxiety, diabetic nerve pain, and depression, where it's rated possibly ineffective.

Talk with your doctor about whether inositol makes sense for your specific situation.

The evidence, ingredient by ingredient Inositol

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Inositol is generally well tolerated at typical doses. The most common side effects are digestive — diarrhea, gas, and nausea — and they're usually mild.

In pregnancy, inositol is rated possibly safe, but safety isn't fully established, so it should only be used under medical supervision if you're pregnant or planning to become pregnant. There isn't enough reliable information about inositol during breastfeeding, so check with your doctor or pharmacist for personalized advice if you're nursing.

Side effects, ingredient by ingredient Inositol

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Inositol.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 86 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before you start inositol, double-check with your doctor or pharmacist if you take any antidiabetes drugs — blood sugar medications paired with inositol carry a Moderate risk of low blood sugar and may need dose adjustment or closer monitoring.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

Inositol may be worth considering if you have PCOS, metabolic syndrome, or are looking to reduce preterm labor risk — but it's most important to talk it over with your doctor or pharmacist first, especially if you take diabetes medication. They can help you figure out whether it's right for you and whether any dose adjustments are needed for your other medications.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jun 25, 2013.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Inositol (Vitamin B8), straight from the product label.

Brand PureBulk.com
Net contents 100 g; 3.53 oz.
Market status On market
Date entered into DSLD Jun 25, 2013
DSLD ID 23122
Product type Non-nutrient/non-botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Inositol (Vitamin B8) by PureBulk.com, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
600 mg
Maximum serving Sizes:
600 mg
Servings per container
166
IngredientAmount% DV
Inositol600 mg--

Other ingredients: None

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements

Derived from corn

US Standard Measuring Spoons Spoon Size (level) milligrams 1/8 teaspoon 341 1/4 teaspoon 683 1/2 teaspoon 1368

Storage

Storage: Keep dry, cool & dark

Formulation

Free of: sugar, soy, dairy, yeast, gluten, and additives.

Suggested/Recommended/Usage/Directions

Directions: As a dietary supplement, take 600 mg (scant 1/4 tsp) daily, or as directed by physician.

Precautions

Warning: This product is not intended for use by those with a serious medical condition or pregnant or lactating women.

Consult your physician before use.

Keep out of reach of children.

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Inositol (Vitamin B8) by PureBulk.com label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Inositol (Vitamin B8) label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Inositol (Vitamin B8) by PureBulk.com

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size600 mg Dosage formPowder Servings per container166 Amounts shown are per serving.

Inositol

Interacts with
86 drugs
600 mg per serving Form: Vitamin B8

Inositol is a sugar alcohol made naturally in the body and found in many foods, and it is sold as a supplement (often myo-inositol) mainly for PCOS, m...

Inositol monograph & interactions

Other (inactive) ingredients: None. These complete the product’s ingredient list but are not active constituents.

Interaction report

Inositol (Vitamin B8) by PureBulk.com Drug Interactions

Want to check YOUR meds against Inositol (Vitamin B8)?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
86Drugs
86 Moderate

Ingredients driving the most interactions

Inositol 86

Individual Drug Interactions

The ingredients in Inositol (Vitamin B8) interact with 86 drugs. Click any drug to see the details.

1 of the 1 ingredient in Inositol (Vitamin B8) interact with drugs. Each result below shows which ingredient is responsible. Inositol

Each ingredient & the kinds of drugs it affects

For each ingredient in Inositol (Vitamin B8) with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Inositol1 drug type · 86 drugs

Antidiabetes Drugs

Theoretically, taking inositol with antidiabetes drugs might increase the risk of hypoglycemia.
Clinical research shows that inositol lowers blood glucose levels and glycated hemoglobin (HbA1c) levels in patients with diabetes.

Likelihood Possible Evidence A
Inositol full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Inositol (Vitamin B8), from the product label.

PureBulk.com

See all PureBulk.com products
Name
PureBulk.com
City
Roseburg
State
OR
ZipCode
97471
Phone Number
(541) 679-1500
Web Address
PureBulk.com
Pharmacist Counseling Corner

Inositol (Vitamin B8) by PureBulk.com: Common Questions

Does Inositol (Vitamin B8) by PureBulk.com interact with any medications?
Yes. Based on its ingredients, Inositol (Vitamin B8) has a known interaction with 86 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Inositol (Vitamin B8) contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does inositol actually work for PCOS?
There's possibly effective evidence for PCOS, which means the research is promising but not conclusive. Many people find it helpful, but talk with your doctor about whether it's right for your situation and how long you might need to take it before you notice a change.
Will inositol give me side effects?
Most people tolerate it well. The main ones are digestive — diarrhea, gas, and nausea — and they're usually mild. If you notice these, you might try a smaller dose or take it with food.
Can I take inositol if I'm pregnant?
Inositol is rated possibly safe in pregnancy, but safety isn't fully established. If you're pregnant or planning to become pregnant, only use it under medical supervision. Talk with your doctor or pharmacist about whether it's appropriate for you.
Is inositol safe to use while breastfeeding?
There isn't enough reliable information about inositol during breastfeeding. Check with your doctor or pharmacist for personalized advice if you're nursing.
What exactly is inositol?
Inositol is a naturally occurring compound in your body that helps with cell signaling and how your cells respond to insulin. You get small amounts from food too, so this supplement is just a concentrated dose.
I take a diabetes medication — can I use this?
Don't start it without checking with your doctor or pharmacist first. Inositol lowers blood sugar, so combining it with diabetes medication creates a risk of low blood sugar. Your doctor may want to monitor your levels or adjust your dose.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Inositol (Vitamin B8) is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Inositol (Vitamin B8) label
Go deeper

The Full Monographs Behind Inositol (Vitamin B8)’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Inositol

Interacts with 86 drugs

Inositol is a sugar alcohol made naturally in the body and found in many foods, and it is sold as a supplement (often myo-inositol) mainly for PCOS, mood, and metabolic concerns. The stronge...

Read the full Inositol monograph →
Sources

Sources & How We Checked

Inositol (Vitamin B8)'s label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 14 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Inositol 14 references
  1. Palatnik A, Frolov K, Fux M, Benjamin J. Double-blind, controlled, crossover trial of inositol versus fluvoxamine for the treatment of panic disorder. J Clin Psychopharmacol 2001;21:335-9.. PubMed
  2. Allan SJ, Kavanagh GM, Herd RM, Savin JA. The effect of inositol supplements on the psoriasis of patients taking lithium: a randomized, placebo-controlled trial. Br J Dermatol 2004;150:966-9. PubMed
  3. Machado-Vieira R, Viale CI, Kapczinski F. Mania associated with an energy drink: the possible role of caffeine, taurine, and inositol. Can J Psychiatry 2001;46:454-5. PubMed
  4. Kamenov Z, Kolarov G, Gateva A, Carlomagno G, Genazzani AD. Ovulation induction with myo-inositol alone and in combination with clomiphene citrate in polycystic ovarian syndrome patients with insulin resistance. Gynecol Endocrinol 2015;31(2):131-5. PubMed
  5. Matarrelli B, Vitacolonna E, D'Angelo M, et al. Effect of dietary myo-inositol supplementation in pregnancy on the incidence of maternal gestational diabetes mellitus and fetal outcomes: a randomized controlled trial. J Matern Fetal Neonatal Med 2013;26(1 PubMed
  6. Mukai T, Kishi T, Matsuda Y, Iwata N. A meta-analysis of inositol for depression and anxiety disorders. Hum Psychopharmacol 2014;29(1):55-63. PubMed
  7. Farren M, Daly N, McKeating A, Kinsley B, Turner MJ, Daly S. The Prevention of Gestational Diabetes Mellitus With Antenatal Oral Inositol Supplementation: A Randomized Controlled Trial. Diabetes Care. 2017;40(6):759-63. PubMed
  8. Zheng X, Liu Z, Zhang Y, et al. Relationship Between Myo-Inositol Supplementary and Gestational Diabetes Mellitus: A Meta-Analysis. Medicine (Baltimore). 2015;94(42):e1604. PubMed
  9. Crawford TJ, Crowther CA, Alsweiler J, Brown J. Antenatal dietary supplementation with myo-inositol in women during pregnancy for preventing gestational diabetes. Cochrane Database Syst Rev. 2015;(12):CD011507. PubMed
  10. Maurizi AR, Menduni M, Del Toro R, et al. A pilot study of D-chiro-inositol plus folic acid in overweight patients with type 1 diabetes. Acta Diabetol. 2017;54(4):361-65. PubMed
  11. Leppink EW, Redden SA, Grant JE. A double-blind, placebo-controlled study of inositol in trichotillomania. Int Clin Psychopharmacol. 2017;32(2):107-14. PubMed
  12. Lam S, Mandrekar SJ, Gesthalter Y. A Randomized Phase IIb Trial of myo-Inositol in Smokers with Bronchial Dysplasia. Cancer Prev Res (Phila). 2016;9(12):906-14.
  13. Wozniak J, Faraone SV, Chan J, et al. A randomized clinical trial of high eicosapentaenoic acid omega-3 fatty acids and inositol as monotherapy and in combination in the treatment of pediatric bipolar spectrum disorders: a pilot study. J Clin Psychiatry. PubMed
  14. Vitale SG, Corrado F, Caruso S, et al. Myo-inositol supplementation to prevent gestational diabetes in overweight non-obese women: bioelectrical impedance analysis, metabolic aspects, obstetric and neonatal outcomes - a randomized and open-label, placebo-

See these in context on the Inositol monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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