Buckthorn Bark Extract Ingredients & Drug Interactions
What is this page for?
First and foremost: checking Buckthorn Bark Extract against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Buckthorn Bark Extract is a dietary supplement by BulkSupplements.com with 1 active ingredient. Its ingredients are commonly taken for constipation, occasional laxative use, digestive complaints.Based on those ingredients, 99 medications have a known interaction with it, the most serious rated major. The ingredients most likely to interact are Buckthorn bark extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
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AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of Buckthorn Bark Extract by BulkSupplements.com
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: buckthorn bark extract. It's a herbal laxative that works by stimulating your bowel to move, and it's been used traditionally to help with constipation.
Does it work?
Moderate evidence
Buckthorn bark extract is possibly effective for constipation based on the evidence we hold. That means there's some data supporting its use, but the research isn't airtight — it's a reasonable option to consider if you're looking for a natural laxative, though you'll want to talk with your doctor or pharmacist about whether it's right for your situation.
How safe is it?
Well-documented data
Short-term use of buckthorn bark is generally well tolerated, but it can cause abdominal pain, cramps, or watery diarrhea. Here's what matters for longer use: chronic use or abuse can lead to potassium depletion, which disturbs heart function and causes muscle weakness.
You may also develop harmless pigment spots in your intestinal lining (pseudomelanosis coli), which usually reverse when you stop taking it. The safety data advises against using buckthorn during pregnancy or while breastfeeding — it's rated likely unsafe for both.
Because it's a harsh stimulant laxative, use it only under professional guidance.
Meds to double-check
Major interaction found
Before taking this product, double-check with your doctor or pharmacist if you take digoxin (a heart medication) — that's a Major interaction. Also flag if you're on warfarin or other blood thinners, diuretics (water pills), or other stimulant laxatives, as those carry Moderate interactions.
Overuse of buckthorn can be risky with these drugs.
The bottom line
Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Major medication interactions have been identified, and safety information is well characterized.
Buckthorn bark extract may help with constipation if you use it short-term and cautiously, but it's not for long-term regular use and carries real risks with certain medications. If you take digoxin, warfarin, diuretics, or other stimulant laxatives, check with your doctor or pharmacist before starting this product.
It's not safe in pregnancy or while nursing. Talk it over with your own healthcare provider to see if it fits your needs.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Aug 23, 2021.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Buckthorn Bark Extract, straight from the product label.
| Brand | BulkSupplements.com |
|---|---|
| Barcode (UPC) | X001BDT5N9 |
| Net contents | 500 Gram(s); 17.6 Oz(s) |
| Market status | On market |
| Date entered into DSLD | Aug 23, 2021 |
| DSLD ID | 253949 |
| Product type | Botanical |
| Supplement form | Powder |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult (18 - 50 Years), Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Buckthorn Bark Extract by BulkSupplements.com, sourced from the NIH Dietary Supplement Label Database.
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
Clean & pure bulk supplements
New - Buckthorn Bark Extract Powder by Bulksupplements (500 grams)
Formulation
Free of: Added sugar, soy, dairy, yeast, gluten, additives.
Color may vary
Suggested/Recommended/Usage/Directions
Suggested use: As a dietary supplement, take 750 mg (about 1/3 tsp) up to three times daily, or as directed by a physician.
Storage
Store in a dry, cool place.
FDA Disclaimer Statement
Warning: This product is not intended to diagnose, treat, cure, or prevent any disease.
Precautions
Always consult a physician before taking any dietary supplement.
Keep out of reach of children.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Buckthorn Bark Extract by BulkSupplements.com label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Buckthorn Bark Extract by BulkSupplements.com
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size750 mg Dosage formPowder Servings per container667 Amounts shown are per serving.
Buckthorn bark extract
Interacts with99 drugs
European Buckthorn is a shrub whose bark and berries contain compounds that act as a strong, irritant-type laxative. Because it can cause cramping, fl...
Buckthorn bark extract monograph & interactionsOther (inactive) ingredients: None. These complete the product’s ingredient list but are not active constituents.
Buckthorn Bark Extract by BulkSupplements.com Drug Interactions
HelloPharmacist Interaction Report
Buckthorn Bark Extract by BulkSupplements.com does interact with several medication types, and the most serious concern is with digoxin (Lanoxin), a heart medication.
Buckthorn is a stimulant laxative, and overuse could theoretically increase how toxic digoxin becomes in your body.
Read the full breakdown — every affected drug type, severity by severity
It also has Moderate interactions with blood thinners like warfarin (Coumadin) — the diarrhea buckthorn can cause may increase warfarin's effects and raise your bleeding risk. Diuretics (water pills) are another concern: buckthorn might worsen the potassium loss these drugs can cause, which could affect your heart rhythm and muscle function.
Don't combine it with other stimulant laxatives, as that would compound fluid and electrolyte loss.
Altogether, these interactions span 99 individual medications. If you take any of these drug types — or any prescription medication — check your exact medications with the search tool below before you start this product.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Buckthorn Bark Extract?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Buckthorn Bark Extract interact with 99 drugs. Click any drug to see the details.
1 of the 1 ingredient in Buckthorn Bark Extract interact with drugs. Each result below shows which ingredient is responsible. Buckthorn bark extract
DigoxinDigitek, Lanoxicaps, Lanoxin
How Digoxin interacts with Buckthorn Bark Extract — through 1 ingredient. Tap an ingredient for the detail:
Buckthorn Bark ExtractDigoxin (lanoxin) Major
Interaction Summary
European buckthorn has stimulant laxative effects.
Read the full Buckthorn Bark Extract + Digoxin interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Buckthorn Bark Extract with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Buckthorn bark extract
Digoxin (Lanoxin)
European buckthorn has stimulant laxative effects. Theoretically, the overuse or abuse of European buckthorn might increase the toxicity of cardiac glycoside drugs.
Diuretic Drugs
European buckthorn has stimulant laxative effects. Theoretically, overuse of European buckthorn might compound diuretic-induced potassium loss. There is some concern that taking European buckthorn along with potassium-depleting diuretics might increase the risk for hypokalemia.
Some diuretics that can deplete potassium include chlorothiazide (Diuril), chlorthalidone (Thalitone), furosemide (Lasix), hydrochlorothiazide (HCTZ, Hydrodiuril, Microzide), and others.
Stimulant Laxatives
European buckthorn has stimulant laxative effects. Concomitant use with stimulant laxative medications might compound fluid and electrolyte loss.
Warfarin (Coumadin)
European buckthorn has stimulant laxative effects, which can cause diarrhea in some people. Diarrhea can increase the effects of warfarin, which can increase the international normalized ratio (INR) and the risk of bleeding. Advise patients who take warfarin not to take excessive amounts of European buckthorn.
Brand information
Manufacturer and brand details for Buckthorn Bark Extract, from the product label.
BulkSupplements.com
See all BulkSupplements.com products- Name
- BulkSupplements.com
- Street Address
- 7511 Eastgate Rd
- City
- Henderson
- State
- NV
- ZipCode
- 89011
- Web Address
- BulkSupplements.com
Buckthorn Bark Extract by BulkSupplements.com: Common Questions
Does Buckthorn Bark Extract by BulkSupplements.com interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Can I take buckthorn bark while I'm pregnant or breastfeeding?
What side effects should I watch for?
How well does buckthorn work for constipation?
Why does the label say to use it only with professional guidance?
What's in this powder besides the active ingredient?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Buckthorn Bark Extract is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Buckthorn Bark Extract’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Buckthorn Bark Extract's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 7 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
European Buckthorn 7 references
- Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
- Tyler VE. Herbs of Choice. Binghamton, NY: Pharmaceutical Products Press, 1994.
- Newall CA, Anderson LA, Philpson JD. Herbal Medicine: A Guide for Healthcare Professionals. London, UK: The Pharmaceutical Press, 1996.
- Schulz V, Hansel R, Tyler VE. Rational Phytotherapy: A Physician's Guide to Herbal Medicine. Terry C. Telger, transl. 3rd ed. Berlin, GER: Springer, 1998.
- McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
- Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
- Nusko G, Schneider B, Schneider I, et al. Anthranoid laxative use is not a risk factor for colorectal neoplasia: results of a prospective case control study. Gut 2000;46:651-5. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC