Interactions on record — worth a quick check against your medications. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

Butcher's Broom Max-V Ingredients & Drug Interactions

by Douglas Laboratories

Butcher's Broom Max-V label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 9, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Butcher's Broom Max-V against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Butcher's Broom Max-V is a dietary supplement by Douglas Laboratories with 2 active ingredients. Its ingredients are commonly taken for chronic venous insufficiency, varicose veins, leg swelling and heaviness.Based on those ingredients, 158 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Butcher's Broom Herbal Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Butcher's Broom Max-V by Douglas Laboratories

Ask about any prescription or over-the-counter medication and we check it for interactions with Butcher's Broom Max-V by Douglas Laboratories — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Butcher's Broom Max-V by Douglas Laboratories

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 16, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Butcher's Broom Max-V contains 2 active ingredients — butcher's broom herbal extract and butcher's broom — both forms of the same plant. The product also includes inactive ingredients (cellulose, silica, and vegetable stearate) that serve as fillers and binders in the capsule.

Butcher's broom has been studied mainly for its effects on how blood moves through your veins, particularly in the legs. The plant contains compounds that may act on blood vessel walls and nerve signals that control blood vessel width.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: circulation and venous health.
  • We looked for evidence on: Chronic venous insufficiency (CVI), Varicose veins, Hemorrhoids, leg swelling, venous function.
  • The strongest evidence on file: Butcher's Broom is rated "Possibly Effective" for Chronic venous insufficiency (CVI) (Natural Medicines).
  • Also on file: Butcher's Broom is rated "Insufficient Reliable Evidence To Rate" for Hemorrhoids, Varicose veins.

Butcher's broom is possibly effective for chronic venous insufficiency (CVI) — a condition where blood pools in the leg veins. For other uses in this product — diabetic damage to the eye, hemorrhoids, low blood pressure when standing up, and swelling from lymph fluid — the evidence we have isn't strong enough to rate whether it works.

The evidence, ingredient by ingredient Butcher's Broom

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Butcher's broom is generally well tolerated for short-term use in healthy adults, but long-term safety data are limited. The most common side effects when taken by mouth are nausea, vomiting, diarrhea, heartburn, indigestion, and stomach irritation.

In rare cases, someone with poorly controlled diabetes reported severe vomiting and diarrhea leading to hospitalization. If applied to skin, it can cause a rash in sensitive people.

The safety data advises against use during pregnancy and breastfeeding because there isn't enough information to know it's safe. If you're pregnant, breastfeeding, or planning either, talk with your doctor or pharmacist before taking this supplement.

Side effects, ingredient by ingredient Butcher's Broom

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Butcher's Broom.
  • The most serious interaction on file is rated Moderate.
  • For scale: 158 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check with your doctor or pharmacist if you take any blood pressure or decongestant medications — especially alpha-adrenergic agonists (like pseudoephedrine or phenylephrine) or alpha-adrenergic antagonists (like doxazosin or terazosin). Butcher's broom may change how these drugs work.

Use the medication checker on this page to see your exact list.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Butcher's Broom Max-V may help with leg vein symptoms if you have chronic venous insufficiency. But it interacts with blood pressure and ADHD medications, so check your exact drug list with your pharmacist before starting.

It's best used short-term, and avoid it if you're pregnant or breastfeeding. Talk it over with your doctor or pharmacist to confirm it fits your health needs.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 2 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Jun 25, 2012.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Butcher's Broom Max-V, straight from the product label.

Brand Douglas Laboratories
Barcode (UPC) 310539001141
Net contents 60 Vegetarian Capsule(s)
Market status On market
Date entered into DSLD Jun 25, 2012
DSLD ID 9556
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Butcher's Broom Max-V by Douglas Laboratories, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Vegetarian Capsule(s)
Maximum serving Sizes:
1 Vegetarian Capsule(s)
UPC/BARCODE
310539001141
IngredientAmount% DV
Butcher's Broom Herbal Extract150 mg--
Butcher's Broom100 mg--

Other ingredients: Cellulose, Silica, Vegetable Stearate

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

Standardized Herbal Extract Supplement

Formula

Butcher's Broom (Ruscus aculeatus L.) of the Liliaceae (Lily) family, contains abundant saponin glycosides called ruscogenins. This extract is standardized at 10% saponin glycosides, calculated as ruscogenins.

10% saponin glycosides calculated as ruscogenins

Suggested/Recommended/Usage/Directions

Suggested Usage: As a dietary supplement, adults take 1 capsule daily between meals or as advised by your health care professional. If digestive irritation occurs, take with meals.

Precautions

Stop use and consult your health care professional if allergic reactions occur.

Note: If pregnant or nursing, consult your health care professional before using this product.

KEEP OUT OF REACH OF CHILDREN.

Tamper resistant package, do not use if outer seal is missing.

Storage

For optimal storage conditions, store in a cool, dry place. (59(0)-77(0)F/15(0)-25(0)C) (35-65% relative humidity)

General

Formula #77310

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Butcher's Broom Max-V by Douglas Laboratories label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Butcher's Broom Max-V label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Butcher's Broom Max-V by Douglas Laboratories

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size1 Vegetarian Capsule(s) Dosage formCapsule Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Butcher's Broom Herbal Extract

Interacts with
158 drugs
150 mg per serving Form: saponin glycosides

Butcher's broom is a plant extract most often used for circulation problems in the legs, such as chronic venous insufficiency, where some evidence sug...

Butcher's Broom Herbal Extract monograph & interactions

Butcher's Broom

Interacts with
158 drugs
100 mg per serving

Butcher's broom is a plant extract most often used for circulation problems in the legs, such as chronic venous insufficiency, where some evidence sug...

Butcher's Broom monograph & interactions

Other (inactive) ingredients: Cellulose, Silica, Vegetable Stearate. These complete the product’s ingredient list but are not active constituents.

Interaction report

Butcher's Broom Max-V by Douglas Laboratories Drug Interactions

Want to check YOUR meds against Butcher's Broom Max-V?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
158Drugs
158 Moderate

Ingredients driving the most interactions

Butcher's Broom Herbal Extract 158

Individual Drug Interactions

The ingredients in Butcher's Broom Max-V interact with 158 drugs. Click any drug to see the details.

1 of the 2 ingredients in Butcher's Broom Max-V interact with drugs. Each result below shows which ingredient is responsible. Butcher's Broom Herbal Extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Butcher's Broom Max-V with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Butcher's Broom Herbal Extract2 drug types · 158 drugs

Alpha-Adrenergic Agonists

Theoretically, butcher's broom might increase the effects and adverse effects of alpha-adrenergic agonists.
Animal and in vitro studies show that butcher's broom has alpha-adrenergic agonist effects.

Likelihood Possible Evidence D
Alpha-Adrenergic Antagonists

Theoretically, butcher's broom might reduce the effects of alpha-adrenergic antagonists.
Animal and in vitro studies show that butcher's broom has alpha-adrenergic agonist effects.

Likelihood Possible Evidence D
Butcher's Broom Herbal Extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Butcher's Broom Max-V, from the product label.

Douglas Laboratories

See all Douglas Laboratories products
Name
Douglas Laboratories
Street Address
600 Boyce Road
City
Pittsburgh
State
PA
ZipCode
15205
Web Address
www.douglaslabs.com
Pharmacist Counseling Corner

Butcher's Broom Max-V by Douglas Laboratories: Common Questions

Does Butcher's Broom Max-V by Douglas Laboratories interact with any medications?
Yes. Based on its ingredients, Butcher's Broom Max-V has a known interaction with 158 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Butcher's Broom Max-V contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take Butcher's Broom Max-V while pregnant or breastfeeding?
The safety data advise against it during pregnancy because there isn't enough information to know it's safe. The same applies to breastfeeding. Talk with your doctor or pharmacist before using this supplement if you're pregnant, breastfeeding, or planning either.
What are the most common side effects?
When taken by mouth, the most common are nausea, vomiting, diarrhea, heartburn, indigestion, and stomach irritation. These tend to be mild and short-term. If you apply it to skin, it can cause a rash in people with sensitive skin.
How long can I safely take this supplement?
The evidence shows it's well tolerated for short-term use in healthy adults, but we don't have good data on long-term safety. Talk with your doctor or pharmacist about how long to take it.
What does butcher's broom actually do?
It's possibly effective for chronic venous insufficiency — a condition where blood pools in leg veins and causes symptoms like swelling and heaviness. For other uses like hemorrhoids or low blood pressure when standing, the evidence isn't strong enough to say whether it works.
Why does this product have two 'butcher's broom' ingredients listed?
Both ingredients are forms of the same plant — one is an herbal extract and one is the plant material itself. Together they make up the active content of the supplement.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Butcher's Broom Max-V is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Butcher's Broom Max-V label
Go deeper

The Full Monographs Behind Butcher's Broom Max-V’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Butcher's Broom

Interacts with 158 drugs

Butcher's broom is a plant extract most often used for circulation problems in the legs, such as chronic venous insufficiency, where some evidence suggests it may help reduce swelling and di...

Read the full Butcher's Broom monograph →
Sources

Sources & How We Checked

Butcher's Broom Max-V's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 8 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Butcher's Broom 8 references
  1. Beltramino R, Penenory A, Buceta AM. An open-label, randomized multicenter study comparing the efficacy and safety of Cyclo 3 Fort versus hydroxyethyl rutoside in chronic venous lymphatic insufficiency. Angiology 2000;51:535-44.. PubMed
  2. Redman DA. Ruscus aculeatus (butcher's broom) as a potential treatment for orthostatic hypotension, with a case report. J Altern Complement Med 2000;6:539-49..
  3. Landa, N., Aguirre, A., Goday, J., Raton, J. A., and Diaz-Perez, J. L. Allergic contact dermatitis from a vasoconstrictor cream. Contact Dermatitis 1990;22(5):290-291. PubMed
  4. Cluzan, R. V., Alliot, F., Ghabboun, S., and Pascot, M. Treatment of secondary lymphedema of the upper limb with CYCLO 3 FORT. Lymphology 1996;29(1):29-35.
  5. Parrado F, Buzzi A. A study of the efficacy and tolerability of a preparation containing Ruscus aculeatus in the treatment of chronic venous insufficiency of the lower limbs. Clin Drug Invest 1999;18(4):255-61. DOI
  6. Sadarmin PP, Timperley J. An unusual case of Butcher's Broom precipitating diabetic ketoacidosis. J Emerg Med 2013;45(3):e63-e65. PubMed
  7. Ramirez-Hernandez M, Garcia-Selles J, Merida-Fernandez C, Martinez-Escribano JA. Allergic contact dermatitis to ruscogenins. Contact Dermatitis 2006;54(1):60. PubMed
  8. European Medicines Agency. Assessment report on Ruscus Aculeatus L rhizome. EMEA/HMPC/261939/2007. London, September 4, 2008. Available at: http://www.ema.europa.eu/docs/en_GB/document_library/Herbal_-_HMPC_assessment_report/2009/12/WC500018288.pdf. Acces

See these in context on the Butcher's Broom monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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