Advantage Plus II By Douglas Laboratories Overview & Drug Interactions

Niacin, also known as vitamin B3, is a water-soluble vitamin found in a variety of foods, including meat, poultry, fish, and fortified grains. It plays a variety of roles in the body, including in the metabolism of carbohydrates, fats, and proteins. It is also necessary for the production of energy in the body and in the synthesis of different hormones. Niacin deficiency is rare in developed countries, however, supplementation has been shown to have several positive benefits. For example, it can reduce the risk of diabetic neuropathy (i.e., nerve pain) and has been shown effective for treating some types of high cholesterol (extended-release niacin is used as a prescription drug in the United States for this purpose). There is a multitude of niacin forms available as dietary supplements, including NADH, niacinamide, and nicotinamide riboside, all with different properties.

Choline is an essential nutrient that is found in many foods, including eggs, and is important for a number of bodily functions, including liver function, brain development, and nerve function. Choline is a precursor to acetylcholine, a neurotransmitter that plays a role in memory, mood, and muscle control. Choline also helps to transport fats out of the liver, which may help to reduce the risk of liver disease. Choline supplements are available in different forms, including choline bitartrate, choline chloride, and phosphatidylcholine. Choline bitartrate is the most common form of choline supplement, but phosphatidylcholine is the form that is found naturally in foods.

Papain is a proteolytic enzyme that is extracted from the papaya fruit. It is also known as papaya proteinase. Proteolytic enzymes are enzymes that break down proteins into smaller peptides and amino acids. Papain specifically breaks down proteins by hydrolyzing the peptide bonds that link amino acids together. Papain is used in a variety of applications, including food production, medicine, and biotechnology. Medically, papain can be used to remove dead tissue from wounds and to treat certain skin conditions. It has also been used to treat sports injuries, such as sprains and strains. Additionally, it is a common ingredient in digestive enzyme dietary supplements to aid in the digestion of proteins.