C2K Ingredients & Drug Interactions
by LG Sciences
What is this page for?
First and foremost: checking C2K against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
C2K is a dietary supplement by LG Sciences with 3 active ingredients. Its ingredients are commonly taken for exercise performance and recovery, heart health, weight management.Based on those ingredients, 191 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Raspberry Ketones, L-Carnitine L-Tartrate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against C2K by LG Sciences
Ask about any prescription or over-the-counter medication and we check it for interactions with C2K by LG Sciences — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of C2K by LG Sciences
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
C2K is a 3-ingredient liquid supplement. The active ingredients are L-carnitine L-tartrate, a compound your body uses to help convert fat into energy; raspberry ketones, a naturally occurring compound in raspberries; and chlorogenic acid, a polyphenol found in coffee and other plants.
The product also contains several inactive ingredients—water, glycerol, citric acid, sodium benzoate, and others—that serve as preservatives, flavor agents, and thickeners.
Does it work?
Strong evidence
L-carnitine is rated effective for L-carnitine deficiency (a condition where your body doesn't have enough of this compound). It's rated possibly effective for high cholesterol, heart failure, and chest pain (angina).
Raspberry ketones and chlorogenic acid don't have established evidence in our data—the evidence for obesity and hair loss with raspberry ketones is insufficient to rate, and we hold no effectiveness data for chlorogenic acid in this product.
How safe is it?
Well-documented data
L-carnitine is generally well tolerated at typical doses, though high doses can cause stomach upset and a fishy body odor. The most common side effects are abdominal cramps, diarrhea, nausea, and heartburn.
Seizures are rare but serious. L-carnitine safety during pregnancy is not well studied—there isn't enough data—and it's possibly safe while breastfeeding, though caution is advised.
Raspberry ketone has very limited human safety data at supplement doses. Because it resembles a stimulant compound, heart palpitations, elevated blood pressure, and dangerous heart rhythms have been reported.
Pregnancy and breastfeeding safety data are not adequate; the safety information advises against supplement use in both. Chlorogenic acid safety information is not on file for this product.
Meds to double-check
Moderate interaction found
Check with your pharmacist before taking C2K if you take blood thinners (warfarin, acenocoumarol), thyroid hormone replacement, or stimulant medications—including some decongestants and ADHD drugs. These interactions are rated Moderate and could change how well your medications work or raise your risk of bleeding or heart problems.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with strong clinical evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.
C2K may be worth considering if you have L-carnitine deficiency or are interested in possible support for cholesterol or heart conditions—but you need to check your medications first. If you take a blood thinner, thyroid medication, or stimulant, talk to your pharmacist before starting.
The raspberry ketone component carries real cardiovascular risks, especially if you have heart disease or take stimulant drugs.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 2 of 3 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated May 23, 2014.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about C2K, straight from the product label.
| Brand | LG Sciences |
|---|---|
| Barcode (UPC) | 616641665814 |
| Net contents | 120 Serving(s); 6 Oz(s); 180 mL |
| Market status | On market |
| Date entered into DSLD | May 23, 2014 |
| DSLD ID | 33485 |
| Product type | Other Combinations |
| Supplement form | Liquid |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Adult Male (18-50 Years) |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for C2K by LG Sciences, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Proprietary Blend | 200 mg | -- |
| L-Carnitine L-Tartrate | 0 NP | -- |
| Raspberry Ketones | 0 NP | -- |
| Chlorogenic Acid | 0 NP | -- |
Other ingredients: Water, Glycerol, HPBCD, Citric Acid, Na Benzoate, Ca EDTA, K Sorbate, N&A Flavor, Sucralose, Ace K, Stevia, Xanthan Gum
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Precautions
KEEP OUT OF REACH OF CHILDREN
WARNING: NOT FOR USE BY INDIVIDUALS UNDER THE AGE OF 18 YEARS WITHOUT CONSENT FROM A PARENT.
Consult a physician or licensed qualified health care professional before using this product if you are using any other dietary supplement, prescription drug, or over-the-counter drug.
Do not exceed recommended serving. Discontinue use and call a physician or licensed qualified health care professional immediately if you experience rapid heart beat, dizziness, blurred vision, or other similar symptoms.
Made in a facility that may process: dairy, peanuts, tree nuts, wheat, fish, barley and shellfish.
Made in a facility that may process: dairy, peanuts, tree nuts, wheat, fish, barley and shellfish.
FDA Disclaimer Statement
THESE STATEMENTS HAVE NOT BEEN EVALUATED BY THE FDA. NOT INTENDED TO DIAGNOSE, TREAT, CURE OR PREVENT ANY DISEASE.
General Statements
all claims are dependant on proper diet and exercise and are only theories based on preliminary scientific studies.
Report An Event 586-933-5781
PLATINUM SERIES
SUPPORTS HEALTHY WEIGHT CONTROL
IMPORTANT LEGAL INFORMATION By purchasing this product you agree:(1)all disputes, claims, and causes of action arising out of or in connection with this product shall be resolved individually, without resort to any form of class action, by binding arbitration to take place in Detroit, MI pursuant to the rules of the American Arbitration Association; (2) all claims, judgments, and awards shall be limited to the actual out-of-pocket amount paid by you to LG Supplements LLC. to purchase the product, but in no event attorney's fees; and (3) under no circumstances will you be allowed to obtain awards for, and you hereby waive all rights to claim punitive, incidental, or consequential damages, any other damages other than actual out-of-pocket expenses, and all rights to have damages multiplied or otherwise increased. A judgment of any circuit court may be rendered upon the arbitration award made pursuant to this agreement. The construction, validity, interpretation and enforceability of this agreement, or the rights and obligations of users and us in connection with this product, shall be governed by and construed in accordance with the laws of Michigan, without giving effect to any choice of law or conflict of law rules or provisions (whether of MI or any other jurisdiction) that would cause the application of the laws of any jurisdiction other than the MI. If any of these terms are found unlawful, void, or for any reason unenforceable, the provision will be considered severable from the remaining terms, and will not affect the validity and enforceability of the remaining provisions. CA Residents ONLY: Arbitration occurs in Redding, CA and the laws of California apply
Formula
GREEN COFFEE BEAN RASPBERRY KETONES
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
Directions: Shake well. Snap down the syringe dispenser or use the dropper. Dispense 1.5 ml under the tongue. Hold the contents under your tongue for 60 seconds, then swish the contents around your mouth and swallow completely. Use 4 doses spread out during the day with at least 30 minutes between doses or whenever you feel hungry.
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
C2K by LG Sciences label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in C2K by LG Sciences
These are the 3 active ingredients this product is made of. Select any to open its full monograph.
Serving size1.5 mL Dosage formLiquid Servings per container120 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Proprietary Blend
- › L-Carnitine L-Tartrate
- › Raspberry Ketones
- › Chlorogenic Acid
Other (inactive) ingredients: Water, Glycerol, HPBCD, Citric Acid, Na Benzoate, Ca EDTA, K Sorbate, N&A Flavor, Sucralose, Ace K, Stevia, Xanthan Gum. These complete the product’s ingredient list but are not active constituents.
C2K by LG Sciences Drug Interactions
HelloPharmacist Interaction Report
LG Sciences' C2K contains L-carnitine and raspberry ketones, both of which have documented interactions with medications.
The most serious concern is L-carnitine's Moderate interaction with blood thinners (anticoagulants): it may increase the anticoagulant effects of warfarin (Coumadin) and acenocoumarol (Sintrom), raising your bleeding risk. There are case reports of INR elevation (a measure of how thin your blood is) when these were combined.
Read the full breakdown — every affected drug type, severity by severity
L-carnitine also has a Moderate interaction with thyroid hormone replacement — it may decrease how well the medication works by blocking thyroid hormone from entering your cells. Raspberry ketones carry a Moderate interaction with stimulant drugs (including some decongestants and ADHD medications), theoretically raising your risk of heart palpitations, high blood pressure, and dangerous heart rhythms.
There's also a case report of raspberry ketone interfering with warfarin, requiring a dose increase to maintain its effect.
We could not check chlorogenic acid — we hold no interaction data for it. Altogether, these interactions span 191 individual medications.
Before you start C2K, run your exact medications through the checker on this page, especially if you take a blood thinner, thyroid medication, or stimulant.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against C2K?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in C2K interact with 191 drugs. Click any drug to see the details.
2 of the 3 ingredients in C2K interact with drugs. Each result below shows which ingredient is responsible. Raspberry Ketones L-Carnitine L-Tartrate
Chlorpheniramine, Phenindamine, PhenylpropanolamineNolamine
How Chlorpheniramine, Phenindamine, Phenylpropanolamine interacts with C2K — through 1 ingredient. Tap an ingredient for the detail:
Raspberry KetonesStimulant Drugs Moderate
Interaction Summary
Theoretically, raspberry ketone might increase the risk of adverse cardiovascular effects with stimulant drugs.
Read the full Raspberry Ketones + Chlorpheniramine, Phenindamine, Phenylpropanolamine interactionChlorpheniramine, PhenylephrineDallergy JR, Ed A Hist, Histatab Plus, Rynatan
How Chlorpheniramine, Phenylephrine interacts with C2K — through 1 ingredient. Tap an ingredient for the detail:
Raspberry KetonesStimulant Drugs Moderate
Interaction Summary
Theoretically, raspberry ketone might increase the risk of adverse cardiovascular effects with stimulant drugs.
Read the full Raspberry Ketones + Chlorpheniramine, Phenylephrine interactionChlorpheniramine, Phenylephrine, PhenylpropanolamineRutuss
How Chlorpheniramine, Phenylephrine, Phenylpropanolamine interacts with C2K — through 1 ingredient. Tap an ingredient for the detail:
Raspberry KetonesStimulant Drugs Moderate
Interaction Summary
Theoretically, raspberry ketone might increase the risk of adverse cardiovascular effects with stimulant drugs.
Read the full Raspberry Ketones + Chlorpheniramine, Phenylephrine, Phenylpropanolamine interactionChlorpheniramine, Phenylephrine, Phenylpropanolamine, PhenyltoloxamineDe Con, Decongest, Naldecon, Nalspan SR, Tri Phen Mine Sr, Uni Decon +1 more
How Chlorpheniramine, Phenylephrine, Phenylpropanolamine, Phenyltoloxamine interacts with C2K — through 1 ingredient. Tap an ingredient for the detail:
Raspberry KetonesStimulant Drugs Moderate
Interaction Summary
Theoretically, raspberry ketone might increase the risk of adverse cardiovascular effects with stimulant drugs.
Read the full Raspberry Ketones + Chlorpheniramine, Phenylephrine, Phenylpropanolamine, Phenyltoloxamine interactionChlorpheniramine, Phenylephrine, Phenylpropanolamine, PyrilamineHistalet Forte, Poly Hist Forte, Vanex Forte
How Chlorpheniramine, Phenylephrine, Phenylpropanolamine, Pyrilamine interacts with C2K — through 1 ingredient. Tap an ingredient for the detail:
Raspberry KetonesStimulant Drugs Moderate
Interaction Summary
Theoretically, raspberry ketone might increase the risk of adverse cardiovascular effects with stimulant drugs.
Read the full Raspberry Ketones + Chlorpheniramine, Phenylephrine, Phenylpropanolamine, Pyrilamine interactionChlorpheniramine, Phenylephrine, PhenyltoloxamineCom Time, Comhist, Comhist LA, Linhist LA, Q Hist LA
How Chlorpheniramine, Phenylephrine, Phenyltoloxamine interacts with C2K — through 1 ingredient. Tap an ingredient for the detail:
Raspberry KetonesStimulant Drugs Moderate
Interaction Summary
Theoretically, raspberry ketone might increase the risk of adverse cardiovascular effects with stimulant drugs.
Read the full Raspberry Ketones + Chlorpheniramine, Phenylephrine, Phenyltoloxamine interactionChlorpheniramine, Phenylephrine, PyrilamineTanamine
How Chlorpheniramine, Phenylephrine, Pyrilamine interacts with C2K — through 1 ingredient. Tap an ingredient for the detail:
Raspberry KetonesStimulant Drugs Moderate
Interaction Summary
Theoretically, raspberry ketone might increase the risk of adverse cardiovascular effects with stimulant drugs.
Read the full Raspberry Ketones + Chlorpheniramine, Phenylephrine, Pyrilamine interactionChlorpheniramine, PhenylpropanolamineAler-Releaf, Conex DA, Contac, Dehist, Histabid Duracaps, Ornade +1 more
How Chlorpheniramine, Phenylpropanolamine interacts with C2K — through 1 ingredient. Tap an ingredient for the detail:
Raspberry KetonesStimulant Drugs Moderate
Interaction Summary
Theoretically, raspberry ketone might increase the risk of adverse cardiovascular effects with stimulant drugs.
Read the full Raspberry Ketones + Chlorpheniramine, Phenylpropanolamine interactionChlorpheniramine, PseudoephedrineA.R.M., Anamine TD, Atrohist, Atrohist Ped, Brexin LA, Children's Deconamine +26 more
How Chlorpheniramine, Pseudoephedrine interacts with C2K — through 1 ingredient. Tap an ingredient for the detail:
Raspberry KetonesStimulant Drugs Moderate
Interaction Summary
Theoretically, raspberry ketone might increase the risk of adverse cardiovascular effects with stimulant drugs.
Read the full Raspberry Ketones + Chlorpheniramine, Pseudoephedrine interactionChlorpheniramine, Pyrilamine, PhenylephrineDuphrene
How Chlorpheniramine, Pyrilamine, Phenylephrine interacts with C2K — through 1 ingredient. Tap an ingredient for the detail:
Raspberry KetonesStimulant Drugs Moderate
Interaction Summary
Theoretically, raspberry ketone might increase the risk of adverse cardiovascular effects with stimulant drugs.
Read the full Raspberry Ketones + Chlorpheniramine, Pyrilamine, Phenylephrine interactionClemastine Fumarate, PhenylpropanolamineTavist-D
How Clemastine Fumarate, Phenylpropanolamine interacts with C2K — through 1 ingredient. Tap an ingredient for the detail:
Raspberry KetonesStimulant Drugs Moderate
Interaction Summary
Theoretically, raspberry ketone might increase the risk of adverse cardiovascular effects with stimulant drugs.
Read the full Raspberry Ketones + Clemastine Fumarate, Phenylpropanolamine interactionCocaine Hydrochloride (prescription Drug)Goprelto, Numbrin
How Cocaine Hydrochloride (prescription Drug) interacts with C2K — through 1 ingredient. Tap an ingredient for the detail:
Raspberry KetonesStimulant Drugs Moderate
Interaction Summary
Theoretically, raspberry ketone might increase the risk of adverse cardiovascular effects with stimulant drugs.
Read the full Raspberry Ketones + Cocaine Hydrochloride (prescription Drug) interactionCodeine Phosphate, PseudoephedrineKg Fed, Nucofed
How Codeine Phosphate, Pseudoephedrine interacts with C2K — through 1 ingredient. Tap an ingredient for the detail:
Raspberry KetonesStimulant Drugs Moderate
Interaction Summary
Theoretically, raspberry ketone might increase the risk of adverse cardiovascular effects with stimulant drugs.
Read the full Raspberry Ketones + Codeine Phosphate, Pseudoephedrine interactionCodeine Phosphate, Pseudoephedrine, TriprolidineCoActifed
How Codeine Phosphate, Pseudoephedrine, Triprolidine interacts with C2K — through 1 ingredient. Tap an ingredient for the detail:
Raspberry KetonesStimulant Drugs Moderate
Interaction Summary
Theoretically, raspberry ketone might increase the risk of adverse cardiovascular effects with stimulant drugs.
Read the full Raspberry Ketones + Codeine Phosphate, Pseudoephedrine, Triprolidine interactionConjugated EstrogensCenestin, Enjuvia, Premarin, Premarin Vaginal Cream
How Conjugated Estrogens interacts with C2K — through 1 ingredient. Tap an ingredient for the detail:
L-carnitine L-tartrateThyroid Hormone Moderate
Interaction Summary
Theoretically, L-carnitine might decrease the effectiveness of thyroid hormone replacement.
Read the full L-carnitine L-tartrate + Conjugated Estrogens interactionDesiccated Thyroid ExtractWesthroid, WP Thyroid
How Desiccated Thyroid Extract interacts with C2K — through 1 ingredient. Tap an ingredient for the detail:
L-carnitine L-tartrateThyroid Hormone Moderate
Interaction Summary
Theoretically, L-carnitine might decrease the effectiveness of thyroid hormone replacement.
Read the full L-carnitine L-tartrate + Desiccated Thyroid Extract interactionDesiccated Thyroid Extract (prescription Drug)Nature-Throid, Thyrar
How Desiccated Thyroid Extract (prescription Drug) interacts with C2K — through 1 ingredient. Tap an ingredient for the detail:
L-carnitine L-tartrateThyroid Hormone Moderate
Interaction Summary
Theoretically, L-carnitine might decrease the effectiveness of thyroid hormone replacement.
Read the full L-carnitine L-tartrate + Desiccated Thyroid Extract (prescription Drug) interactionDexamfetamineDexamfetamine
How Dexamfetamine interacts with C2K — through 1 ingredient. Tap an ingredient for the detail:
Raspberry KetonesStimulant Drugs Moderate
Interaction Summary
Theoretically, raspberry ketone might increase the risk of adverse cardiovascular effects with stimulant drugs.
Read the full Raspberry Ketones + Dexamfetamine interactionDexbrompheniramine, PseudoephedrineDisophrol, Drexophed Sr, Drixoral, Pharmadrine
How Dexbrompheniramine, Pseudoephedrine interacts with C2K — through 1 ingredient. Tap an ingredient for the detail:
Raspberry KetonesStimulant Drugs Moderate
Interaction Summary
Theoretically, raspberry ketone might increase the risk of adverse cardiovascular effects with stimulant drugs.
Read the full Raspberry Ketones + Dexbrompheniramine, Pseudoephedrine interactionDexmethylphenidateFocalin
How Dexmethylphenidate interacts with C2K — through 1 ingredient. Tap an ingredient for the detail:
Raspberry KetonesStimulant Drugs Moderate
Interaction Summary
Theoretically, raspberry ketone might increase the risk of adverse cardiovascular effects with stimulant drugs.
Read the full Raspberry Ketones + Dexmethylphenidate interactionDextroamphetamineDexedrine
How Dextroamphetamine interacts with C2K — through 1 ingredient. Tap an ingredient for the detail:
Raspberry KetonesStimulant Drugs Moderate
Interaction Summary
Theoretically, raspberry ketone might increase the risk of adverse cardiovascular effects with stimulant drugs.
Read the full Raspberry Ketones + Dextroamphetamine interactionDextroamphetamine (patch)Xelstrym
How Dextroamphetamine (patch) interacts with C2K — through 1 ingredient. Tap an ingredient for the detail:
Raspberry KetonesStimulant Drugs Moderate
Interaction Summary
Theoretically, raspberry ketone might increase the risk of adverse cardiovascular effects with stimulant drugs.
Read the full Raspberry Ketones + Dextroamphetamine (patch) interactionDextroamphetamine SulphateDexedrine Spansule
How Dextroamphetamine Sulphate interacts with C2K — through 1 ingredient. Tap an ingredient for the detail:
Raspberry KetonesStimulant Drugs Moderate
Interaction Summary
Theoretically, raspberry ketone might increase the risk of adverse cardiovascular effects with stimulant drugs.
Read the full Raspberry Ketones + Dextroamphetamine Sulphate interactionDextromethorphan Hbr, Phenylephrine HclVicks Formula 44D Cough & Head Congestion Relief
How Dextromethorphan Hbr, Phenylephrine Hcl interacts with C2K — through 1 ingredient. Tap an ingredient for the detail:
Raspberry KetonesStimulant Drugs Moderate
Interaction Summary
Theoretically, raspberry ketone might increase the risk of adverse cardiovascular effects with stimulant drugs.
Read the full Raspberry Ketones + Dextromethorphan Hbr, Phenylephrine Hcl interactionDextromethorphan, Guaifenesin, PhenylephrineAlbatussin Sr, Giltuss
How Dextromethorphan, Guaifenesin, Phenylephrine interacts with C2K — through 1 ingredient. Tap an ingredient for the detail:
Raspberry KetonesStimulant Drugs Moderate
Interaction Summary
Theoretically, raspberry ketone might increase the risk of adverse cardiovascular effects with stimulant drugs.
Read the full Raspberry Ketones + Dextromethorphan, Guaifenesin, Phenylephrine interactionDextromethorphan, Guaifenesin, PhenylpropanolamineProfen LA
How Dextromethorphan, Guaifenesin, Phenylpropanolamine interacts with C2K — through 1 ingredient. Tap an ingredient for the detail:
Raspberry KetonesStimulant Drugs Moderate
Interaction Summary
Theoretically, raspberry ketone might increase the risk of adverse cardiovascular effects with stimulant drugs.
Read the full Raspberry Ketones + Dextromethorphan, Guaifenesin, Phenylpropanolamine interactionDextromethorphan, Guaifenesin, PseudoephedrineMaxifed DM, Med Rx DM, Medent DM, Panmist DM, Profen Forte DM, Profen II DM +4 more
How Dextromethorphan, Guaifenesin, Pseudoephedrine interacts with C2K — through 1 ingredient. Tap an ingredient for the detail:
Raspberry KetonesStimulant Drugs Moderate
Interaction Summary
Theoretically, raspberry ketone might increase the risk of adverse cardiovascular effects with stimulant drugs.
Read the full Raspberry Ketones + Dextromethorphan, Guaifenesin, Pseudoephedrine interactionDextromethorphan, Guaifenesin, PsuedoephedrineAquatab C
How Dextromethorphan, Guaifenesin, Psuedoephedrine interacts with C2K — through 1 ingredient. Tap an ingredient for the detail:
Raspberry KetonesStimulant Drugs Moderate
Interaction Summary
Theoretically, raspberry ketone might increase the risk of adverse cardiovascular effects with stimulant drugs.
Read the full Raspberry Ketones + Dextromethorphan, Guaifenesin, Psuedoephedrine interactionDextromethorphan, Methscopolamine, PhenylephrineDA Chewable
How Dextromethorphan, Methscopolamine, Phenylephrine interacts with C2K — through 1 ingredient. Tap an ingredient for the detail:
Raspberry KetonesStimulant Drugs Moderate
Interaction Summary
Theoretically, raspberry ketone might increase the risk of adverse cardiovascular effects with stimulant drugs.
Read the full Raspberry Ketones + Dextromethorphan, Methscopolamine, Phenylephrine interactionDextromethorphan, PseudoephedrineSudafed Cold/Flu
How Dextromethorphan, Pseudoephedrine interacts with C2K — through 1 ingredient. Tap an ingredient for the detail:
Raspberry KetonesStimulant Drugs Moderate
Interaction Summary
Theoretically, raspberry ketone might increase the risk of adverse cardiovascular effects with stimulant drugs.
Read the full Raspberry Ketones + Dextromethorphan, Pseudoephedrine interactionEach ingredient & the kinds of drugs it affects
For each ingredient in C2K with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Raspberry Ketones
Stimulant Drugs
Theoretically, raspberry ketone might increase the risk of adverse cardiovascular effects with stimulant drugs.
Structurally, raspberry ketone resembles synephrine, a known stimulant agent. Heart palpitations, elevated blood pressure, coronary vasospasm, pulseless electrical activity arrest, and resistant polymorphic ventricular tachycardia have been reported in patients taking raspberry ketone.
Warfarin (Coumadin)
Theoretically, raspberry ketone might increase warfarin dose requirements.
In one case report, a patient taking warfarin 55 mg per week had a decrease in INR over a period of one month while taking raspberry ketone 250 mg daily. A warfarin dose increase to 70 mg per week was necessary to maintain a therapeutic INR while taking raspberry ketone. The mechanism for this potential interaction is not known.
L-Carnitine L-Tartrate
Acenocoumarol (Sintrom)
Theoretically, L-carnitine might increase the anticoagulant effects of acenocoumarol.
L-carnitine might enhance the anticoagulant effects of acenocoumarol, an oral anticoagulant similar to warfarin, but shorter-acting. There are at least two case reports of INR elevation with concomitant use. In one case, a 33-year-old male with a previously stable INR had an elevated INR of 4.65 after L-carnitine was started and continued for 10 weeks. INR normalized after discontinuation of the L-carnitine-containing product.
Thyroid Hormone
Theoretically, L-carnitine might decrease the effectiveness of thyroid hormone replacement.
L-carnitine appears to act as a peripheral thyroid hormone antagonist by inhibiting entry of thyroid hormone into the nucleus of cells. Taking L-carnitine also seems to diminish some of the symptoms of hyperthyroidism.
Warfarin (Coumadin)
Theoretically, L-carnitine might increase the anticoagulant effects of warfarin.
L-carnitine might increase the anticoagulant effects of acenocoumarol, a shorter-acting oral anticoagulant similar to warfarin. There is not enough information to know whether this interaction occurs with L-carnitine and warfarin.
Brand information
Manufacturer and brand details for C2K, from the product label.
C2K by LG Sciences: Common Questions
Does C2K by LG Sciences interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What is L-carnitine L-tartrate and what does it do?
Can I take C2K if I'm pregnant or breastfeeding?
What side effects should I watch for?
Does this supplement actually help with weight loss or fat burning?
What's in this product besides the active ingredients?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if C2K is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind C2K’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
L-carnitine
Interacts with 19 drugsL-carnitine is a compound your body makes naturally and also gets from foods like meat. It helps cells turn fat into energy, and supplements are most clearly useful for people with a true ca...
Read the full L-carnitine monograph → Herb & supplement monographRaspberry Ketone
Interacts with 174 drugsRaspberry ketone is a natural aroma compound found in red raspberries that is heavily marketed for weight loss, but there is no good human evidence that it helps people lose weight. Most cla...
Read the full Raspberry Ketone monograph →Sources & How We Checked
C2K's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 45 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
L-carnitine 41 references
- Ellaway CM, Williams K, Leonard H, et al. Rett syndrome: randomized controlled trial of L-carnitine. J Child Neurol 1999;14:162-7. PubMed
- Anon. Carnitor (levocarnitine) package insert. Sigma-Tau Pharmaceuticals Inc, Gaithersburg, MD. December 1999.
- Cherchi A, Lai C, Angelino F, et al. Effects of L-carnitine on exercise tolerance in chronic stable angina: a multicenter, double-blind, randomized, placebo-controlled, crossover study. Int J Clin Pharmacol Ther Toxicol 1985;23:569-72.
- Plioplys AV, Plioplys S. Amantadine and L-carnitine treatment of Chronic Fatigue Syndrome. Neuropsychobiology 1997;35:16-23. PubMed
- Benvenga S, Ruggeri RM, Russo A, et al. Usefulness of L-carnitine, a naturally occurring peripheral antagonist of thyroid hormone action, in iatrogenic hyperthyroidism: a randomized, double-blind, placebo-controlled clinical trial. J Clin Endocrinol Meta
- Martinez E, Domingo P, Roca-Cusachs A. Potentiation of acenocoumarol action by L-carnitine. J Intern Med 1993;233:94.
- Bachmann HU, Hoffmann A. Interaction of food supplement L-carnitine with oral anticoagulant acenocoumarol. Swiss Med Wkly 2004;134:385. PubMed
- Evans AM, Fornasini G. Pharmacokinetics of L-carnitine. Clin Pharmacokinet 2003;42:941-67. PubMed
- 12761 Benvenga S, Amato A, Calvani M, Trimarchi F. Effects of carnitine on thyroid hormone action. Ann N Y Acad Sci 2004;1033:158-67. PubMed
- Ciacci C, Peluso G, Iannoni E, et al. L-Carnitine in the treatment of fatigue in adult celiac disease patients: a pilot study. Dig Liver Dis 2007;39:922-8. PubMed
- Cruciani RA, Dvorkin E, Homel P, et al. Safety, tolerability and symptom outcomes associated with L-carnitine supplementation in patients with cancer, fatigue, and carnitine deficiency: a phase I/II study. J Pain Symptom Manage 2006;32:551-9. PubMed
- Lebrun C, Alchaar H, Candito M, et al. Levocarnitine administration in multiple sclerosis patients with immunosuppressive therapy-induced fatigue. Mult Scler 2006;12:321-4. PubMed
- Malaguarnera M, Cammalleri L, Gargante MP, et al. L-Carnitine treatment reduces severity of physical and mental fatigue and increases cognitive functions in centenarians: a randomized and controlled clinical trial. Am J Clin Nutr 2007;86:1738-44. PubMed
- Mantovani G, Maccio A, Madeddu C, et al. Randomized phase III clinical trial of five different arms of treatment in 322 patients with cancer cachexia. Oncologist 2010;15:200-11.
- Angelova-Fischer I, Rippke F, Fischer TW, Neufang G, Zillikens D. A double-blind, randomized, vehicle-controlled efficacy assessment study of a skin care formulation for improvement of mild to moderately severe acne. J Eur Acad Dermatol Venereol. 2013 Jul PubMed
- Hatamkhani S, Khalili H, Karimzadeh I, Dashti-Khavidaki S, Abdollahi A, Jafari S. Carnitine for prevention of antituberculosis drug-induced hepatotoxicity: a randomized, clinical trial. J Gastroenterol. Hepatol. 2014 May;29(5):997-1004. PubMed
- Boehm G, Stahl B. Oligosaccharides from milk. J Nutr 2007;137(3 Suppl 2):847S-849S.
- Van Oudheusden, L. J. and Scholte, H. R. Efficacy of carnitine in the treatment of children with attention-deficit hyperactivity disorder. Prostaglandins Leukot.Essent.Fatty Acids 2002;67(1):33-38. PubMed
- Derosa, G., Cicero, A. F., Gaddi, A., Mugellini, A., Ciccarelli, L., and Fogari, R. The effect of L-carnitine on plasma lipoprotein(a) levels in hypercholesterolemic patients with type 2 diabetes mellitus. Clin Ther 2003;25(5):1429-1439. PubMed
- Foitzik, K., Hoting, E., Heinrich, U., Tronnier, H., and Paus, R. Indications that topical L-carnitin-L-tartrate promotes human hair growth in vivo. J Dermatol.Sci 2007;48(2):141-144. PubMed
- Kumar, A., Singh, R. B., Saxena, M., Niaz, M. A., Josh, S. R., Chattopadhyay, P., Mechirova, V., Pella, D., and Fedacko, J. Effect of carni Q-gel (ubiquinol and carnitine) on cytokines in patients with heart failure in the Tishcon study. Acta Cardiol. 20
- Cruciani, R. A., Dvorkin, E., Homel, P., Culliney, B., Malamud, S., Lapin, J., Portenoy, R. K., and Esteban-Cruciani, N. L-carnitine supplementation in patients with advanced cancer and carnitine deficiency: a double-blind, placebo-controlled study. J Pa PubMed
- Malaguarnera, M., Vacante, M., Avitabile, T., Malaguarnera, M., Cammalleri, L., and Motta, M. L-Carnitine supplementation reduces oxidized LDL cholesterol in patients with diabetes. Am J Clin.Nutr 2009;89(1):71-76. PubMed
- Alvarez, T. M., Guardiola, P. D., Roldan, J. O., Elviro, R., Wevers, R., and Guijarro, G. [Primary trimethylaminuria: the fish odor syndrome]. Endocrinol.Nutr. 2009;56(6):337-340.
- Wu, Z. M., Lu, X., Wang, Y. W., Sun, J., Tao, J. W., Yin, F. H., and Cheng, H. J. [Short-term medication of L-carnitine before intracytoplasmic sperm injection for infertile men with oligoasthenozoospermia]. Zhonghua Nan.Ke.Xue 2012;18(3):253-256.
- Tarighat, Esfanjani A., Mahdavi, R., Ebrahimi, Mameghani M., Talebi, M., Nikniaz, Z., and Safaiyan, A. The effects of magnesium, L-carnitine, and concurrent magnesium-L-carnitine supplementation in migraine prophylaxis. Biol.Trace Elem.Res 2012;150(1-3): PubMed
- DiNicolantonio, J. J., Lavie, C. J., Fares, H., Menezes, A. R., and O'Keefe, J. H. L-carnitine in the secondary prevention of cardiovascular disease: systematic review and meta-analysis. Mayo Clin Proc. 2013;88(6):544-551. PubMed
- Huang, W. W., Wang, M. Y., Shi, H. M., Peng, Y., Peng, C. S., Zhang, M., Li, Y., Lu, J., and Li, X. B. Comparative study of bioactive constituents in crude and processed Glycyrrhizae radix and their respective metabolic profiles in gastrointestinal tract
- Madsen KL, Preisler N, Orngreen MC, Andersen SP, Olesen JH, Lund AM, Vissing J. Patients with medium-chain acyl-coenzyme a dehydrogenase deficiency have impaired oxidation of fat during exercise but no effect of L-carnitine supplementation. J Clin Endocri
- Prohaska ES, Muzyk AJ, Rivelli SK. Levocarnitine-induced hypophosphatemia in a hemodialysis patient with acute valproic acid toxicity. J Neuropsychiatry Clin Neurosci. 2012 Winter;24(1):E18-9. PubMed
- Shang R, Sun Z, Li H. Effective dosing of L-carnitine in the secondary prevention of cardiovascular disease: a systematic review and meta-analysis. BMC Cardiovasc Disord. 2014 Jul 21;14:88. PubMed
- Zhang JJ, Wu ZB, Cai YJ, Ke B, Huang YJ, Qiu CP, Yang YB, Shi LY, Qin J. L-carnitine ameliorated fasting-induced fatigue, hunger, and metabolic abnormalities in patients with metabolic syndrome: a randomized controlled study. Nutr J. 2014 Nov 26;13:110. PubMed
- Koeth RA, Wang Z, Levison BS, Buffa JA, Org E, Sheehy BT, Britt EB, Fu X, Wu Y, Li L, Smith JD, DiDonato JA, Chen J, Li H, Wu GD, Lewis JD, Warrier M, Brown JM, Krauss RM, Tang WH, Bushman FD, Lusis AJ, Hazen SL. Intestinal microbiota metabolism of L-carn
- Jun DW, Kim BI, Cho YK, Kim HJ, Kwon YO, Park SY, Han SY, Baek YH, Jung YJ, Kim HY, Kim W, Heo J, Woo HY, Hwang SG, Rim KS, Choi JY, Bae SH, Lee YS, Lim YS,Cheong JY, Cho SW, Lee BS, Kim SH, Sohn JH, Kim TY, Paik YH, Kim JK, Lee KS. Efficacy and safety of
- An JH, Kim YJ, Kim KJ, et al. L-carnitine supplementation for the management of fatigue in patients with hypothyroidism on levothyroxine treatment: a randomized, double-blind, placebo-controlled trial. Endocr J. 2016;63(10):885-95. PubMed
- Chen N, Yang M, Zhou M, Xiao J, Guo J, He L. L-carnitine for cognitive enhancement in people without cognitive impairment. Cochrane Database Syst Rev. 2017;3:CD009374. PubMed
- Khajeh B, Dashti-Khavidaki S, Nasiri-Toosi M, Mohammadi K, Jafari A. Effects of pre-transplant L-carnitine supplementation on primary graft dysfunction in liver transplant recipients: a pilot, randomized, placebo-controlled clinical trial. Res Pharm Sci. PubMed
- Kubota K, Uojima H, Shao X, et al. Additional L-carnitine Reduced the Risk of Hospitalization in Patients with Overt Hepatic Encephalopathy on Rifaximin. Dig Dis 2021. PubMed
- Amini L, Yaghini O, Ghazavi M, Aslani N. L-carnitine versus propranolol for pediatric migraine prophylaxis. Iran J Child Neurol 2021;15(2):77-86.
- Shakibaei F, Jelvani D. Effect of adding l -carnitine to risperidone on behavioral, cognitive, social, and physical symptoms in children and adolescents with autism: A randomized double-blinded placebo-controlled clinical trial. Clin Neuropharmacol 2023;4 PubMed
- Moustafa I, Connolly C, Anis M, Mustafa H, Oosthuizen F, Viljoen M. A prospective study to evaluate the efficacy and safety of vitamin E and levocarnitine prophylaxis against doxorubicin-induced cardiotoxicity in adult breast cancer patients. J Oncol Phar PubMed
Raspberry Ketone 4 references
- Adverse Event Report. Raspberry Ketone. Natural MedWatch, April 27, 2012.
- Adverse Event Report. Raspberry Ketone. Natural MedWatch, September 18, 2011.
- Ansari SA, Patel F, Ashouri D, Dhaliwal JSS, Desai A. Resistant Polymorphic Ventricular Tachycardia in a Patient Taking Raspberry Ketones Weight Loss Supplement. Cureus 2022;14(12):e33089. PubMed
- Khattar A, Beeton I. Coronary vasospasm and raspberry ketones weight-loss supplement: Is there a connection? Anatol J Cardiol. 2020;24(3):205-208.
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