Interactions on record — worth a quick check against your medications. Check your meds →
Dietary supplement

Calanus Oil Ingredients & Drug Interactions

by California Gold Nutrition

Calanus Oil label
See full label image
Softgel Capsule Category: Other Combinations
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Calanus Oil against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Calanus Oil is a dietary supplement by California Gold Nutrition with 1 active ingredient. Its ingredients are commonly taken for heart and metabolic health, source of omega-3 fatty acids, anti-inflammatory support.Based on those ingredients, 671 medications have a known interaction with it, the most serious rated moderate. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Calanus Oil by California Gold Nutrition

Ask about any prescription or over-the-counter medication and we check it for interactions with Calanus Oil by California Gold Nutrition — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Calanus Oil by California Gold Nutrition

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 16, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 4 of its 4 active ingredients.
  • “Total Omega-3 Fatty Acids” is listed as a grouped ingredient — the label gives one combined amount (90 mg) without saying how much of each component you get.
  • “Calanus Oil” is listed as a grouped ingredient — the label gives one combined amount (500 mg) without saying how much of each component you get.

This product contains 4 active ingredients. Astaxanthin is a carotenoid (a type of antioxidant) sourced from calanus oil, which is derived from a small marine crustacean.

The formula also includes eicosapentaenoic acid, docosahexaenoic acid, and stearidonic acid — all omega-3 fatty acids. Each softgel capsule is filled with gelatin, purified water, vegetable glycerin, and sorbitol as inactive ingredients.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Astaxanthin product and its label doesn't state a use — see Astaxanthin's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

Our data shows insufficient evidence to rate astaxanthin for age-related cognitive decline, age-related macular degeneration (AMD), aging skin, Alzheimer disease, athletic performance, or carpal tunnel syndrome. That doesn't mean it doesn't work — it means the evidence available isn't strong enough yet to say whether it does.

The evidence, ingredient by ingredient Calanus Oil Astaxanthin

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Astaxanthin is generally well tolerated in studies, though long-term safety data are limited. The most common side effects reported orally are abdominal pain, diarrhea, and red-colored stools.

A small number of trial participants at higher doses (40 mg daily) experienced severe stomach pain; lower doses caused increased bowel movements and red fecal color in a small number of cases. There isn't enough safety data to use this product during pregnancy or while breastfeeding — talk with your doctor or pharmacist for personalized advice.

Side effects, ingredient by ingredient Calanus Oil Astaxanthin

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Astaxanthin.
  • The most serious interaction on file is rated Moderate.
  • For scale: 672 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check with your doctor or pharmacist before taking this if you use any medications broken down by your liver's CYP3A4 enzyme (a Moderate interaction) or CYP2B6 enzyme (also Moderate). These pathways handle a large number of drugs.

We could not check the omega-3 fatty acid components, so mention this product to your healthcare provider when you discuss it.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Calanus Oil may be worth considering if you're interested in astaxanthin and omega-3s, but the evidence for what it actually does isn't established in our data. The main caution is its theoretical interaction with medications metabolized by CYP3A4 and CYP2B6 — two busy liver pathways.

Before you start, check your exact medications with your doctor or pharmacist to make sure they won't be affected.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Feb 21, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Calanus Oil, straight from the product label.

Brand California Gold Nutrition
Barcode (UPC) 898220019984
Net contents 30 Fish Gelatin Softgel(s)
Market status On market
Date entered into DSLD Feb 21, 2023
DSLD ID 273224
Product type Other Combinations
Supplement form Softgel Capsule
Dietary claims / uses Nutrient, All Other
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Calanus Oil by California Gold Nutrition, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Softgel(s)
Maximum serving Sizes:
1 Softgel(s)
Servings per container
30
UPC/BARCODE
898220019984
IngredientAmount% DV
Total Fat0.5 Gram(s)1%
Astaxanthin300 mcg--
Calories5 Calorie(s)--
Eicosapentaenoic Acid15 mg--
Total Omega-3 Fatty Acids90 mg--
Calanus Oil500 mg--
Stearidonic Acid20 mg--
Docosahexaenoic Acid20 mg--

Other ingredients: Gelatin, Water, Purified, Vegetable Glycerin, Sorbitol

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested Usage: Take 1 softgel daily, with food. Best when taken as directed by a qualified healthcare professional.

Precautions

Warnings: Keep out of reach of children.

Pregnant or lactating women, the chronically ill, elderly, individuals under the age of 18, those taking prescription medications (e.g., blood thinners) as well as those with a physician-diagnosed medical condition should consult with a physician, pharmacist, naturopath or other qualified healthcare professional prior to taking dietary supplements.

Pregnant or lactating women, the chronically ill, elderly, individuals under the age of 18, those taking prescription medications (e.g., blood thinners) as well as those with a physician-diagnosed medical condition should consult with a physician, pharmacist, naturopath or other qualified healthcare professional prior to taking dietary supplements.

Sealed for your protection. Do not use if seal is missing or broken.

Contains: Fish (Tilapia) and Crustacean Shellfish (Calanus Oil).

This product is not manufactured with milk, eggs, tree nuts, peanuts, wheat, soy, sesame or gluten. Produced in a third-party, audited and registered cGMP compliant facility that may process other products that contain these allergens or ingredients.

Storage

Best stored at controlled room temperature 20 degrees C to 25 degrees C (88 degrees F to 77 degrees F). Improper storage conditions, such as extended exposure to direct sunlight, high heat & humidity can cause product degradation over time.

Brand IP Statement(s)

California Gold Nutrition is a registered trademark of Madre Labs, LLC

Formula

Arctic Omega-3s from Calanus finmarchicus EPA, DHA, SDA, Astaxanthin

Formulation

Formulated to Contain No gluten No GMOs No Soy

This product is not manufactured with milk, eggs, tree nuts, peanuts, wheat, soy, sesame or gluten.

FDA Statement of Identity

Dietary Supplement

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Calanus Oil by California Gold Nutrition label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Calanus Oil label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Calanus Oil by California Gold Nutrition

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Softgel(s) Dosage formSoftgel Capsule Servings per container30 Amounts shown are per serving.

Calanus Oil

No known
interactions
500 mg per serving Form: Marine Zooplankton

Calanus oil is a marine omega-3 oil made from a small Arctic zooplankton (Calanus finmarchicus). It is rich in omega-3 fatty acids bound in a unique '...

Calanus Oil monograph & interactions

Other (inactive) ingredients: Gelatin, Water, Purified, Vegetable Glycerin, Sorbitol. These complete the product’s ingredient list but are not active constituents.

Interaction report

Calanus Oil by California Gold Nutrition Drug Interactions

Want to check YOUR meds against Calanus Oil?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
671Drugs
671 Moderate

Ingredients driving the most interactions

Individual Drug Interactions

The ingredients in Calanus Oil interact with 671 drugs. Click any drug to see the details.

0 of the 1 ingredient in Calanus Oil interact with drugs. Each result below shows which ingredient is responsible.

Each ingredient & the kinds of drugs it affects

For each ingredient in Calanus Oil with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

The maker

Brand information

Manufacturer and brand details for Calanus Oil, from the product label.

California Gold Nutrition

See all California Gold Nutrition products
Name
Madre Labs, LLC
Street Address
301 North Lake Avenue, Suite 500
City
Pasadena
State
CA
ZipCode
91101
Web Address
www.calgn.com
Pharmacist Counseling Corner

Calanus Oil by California Gold Nutrition: Common Questions

Does Calanus Oil by California Gold Nutrition interact with any medications?
Yes. Based on its ingredients, Calanus Oil has a known interaction with 671 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Calanus Oil contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take Calanus Oil if I'm pregnant or breastfeeding?
There isn't enough safety data for astaxanthin during pregnancy or while breastfeeding. Talk with your doctor or pharmacist before using this product if you're pregnant, planning to become pregnant, or nursing.
What are the most common side effects?
Abdominal pain, diarrhea, and red-colored stools are the most commonly reported side effects. These are usually mild, though higher doses have caused severe stomach pain in a small number of trial participants.
Is astaxanthin safe long term?
Astaxanthin is generally well tolerated in studies, but long-term safety data are limited. If you plan to use this product regularly, discuss it with your doctor or pharmacist.
Does this product work for age-related macular degeneration or other eye problems?
Our data shows insufficient evidence to say whether astaxanthin works for age-related macular degeneration or other conditions listed. That means the evidence isn't strong enough yet — not that it doesn't work.
What is astaxanthin?
Astaxanthin is a carotenoid — a type of antioxidant found in marine organisms like the small crustacean that produces calanus oil. It gives the oil its reddish color.
Why does my stool turn red when I take this?
Red-colored stools are a reported side effect of astaxanthin and are likely due to the pigment itself passing through your digestive system. It's not dangerous, just a harmless color change.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Calanus Oil is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Calanus Oil label
Go deeper

The Full Monographs Behind Calanus Oil’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Calanus Oil

Calanus oil is a marine omega-3 oil made from a small Arctic zooplankton (Calanus finmarchicus). It is rich in omega-3 fatty acids bound in a unique 'wax ester' form, and early research sugg...

Read the full Calanus Oil monograph → Herb & supplement monograph

Astaxanthin

Interacts with 671 drugs

Astaxanthin is a reddish carotenoid pigment with strong antioxidant activity in the lab, and it is widely promoted for skin, eye, heart, and exercise benefits. Early human studies are promis...

Read the full Astaxanthin monograph →
Sources

Sources & How We Checked

Calanus Oil's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 6 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Astaxanthin 3 references
  1. Kupcinskas L, Lafolie P, Lignell A, et al. Efficacy of the natural antioxidant astaxanthin in the treatment of functional dyspepsia in patients with or without Helicobacter pylori infection: A prospective, randomized, double blind, and placebo-controlled
  2. Kistler, A., Liechti, H., Pichard, L., Wolz, E., Oesterhelt, G., Hayes, A., and Maurel, P. Metabolism and CYP-inducer properties of astaxanthin in man and primary human hepatocytes. Arch.Toxicol. 2002;75(11-12):665-675. PubMed
  3. Choi HD, Youn YK, Shin WG. Positive effects of astaxanthin on lipid profiles and oxidative stress in overweight subjects. Plant Foods Hum Nutr. 2011;66:363-369. PubMed

See these in context on the Astaxanthin monograph →

Calanus Oil 3 references
  1. Cook CM, Larsen TS, Derrig LD, Kelly KM, Tande KS. Wax ester rich oil from the marine crustacean, Calanus finmarchicus, is a bioavailable source of EPA and DHA for human consumption. Lipids. 2016;51(10):1137-1144.
  2. Tande KS, Vo TD, Lynch BS. Clinical safety evaluation of marine oil derived from Calanus finmarchicus. Regul Toxicol Pharmacol. 2016;80:25-31. PubMed
  3. Dadová K, Petr M, Steffl M, et al. Effect of calanus oil supplementation and 16 week exercise program on selected fitness parameters in older women. Nutrients. 2020 Feb 14;12(2):481. PubMed

See these in context on the Calanus Oil monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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