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Dietary supplement

Chaga Ingredients & Drug Interactions

by Exploding Buds

Chaga label
See full label image
Powder Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Chaga against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Chaga is a dietary supplement by Exploding Buds with 1 active ingredient. Its ingredients are commonly taken for immune support, antioxidant support, general wellness/tonic.Based on those ingredients, 327 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Chaga. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Chaga by Exploding Buds

Ask about any prescription or over-the-counter medication and we check it for interactions with Chaga by Exploding Buds — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Chaga by Exploding Buds

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 16, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: chaga, a fungus that grows on birch trees and is traditionally used in teas and foods. That's all — there are no other inactive ingredients listed.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Chaga product and its label doesn't state a use — see Chaga's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence we hold shows insufficient reliable data to rate chaga for cardiovascular disease, diabetes, or COVID-19. While traditional use and some lab work exist, human studies strong enough to confirm whether it works for these purposes aren't in our data yet.

The evidence, ingredient by ingredient Chaga

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Chaga is generally used in foods and teas, but human safety data are limited and a few risks have been reported. The main concern is kidney function: there have been two cases of kidney failure and one case of kidney damage tied to heavy chaga use, likely because it contains high amounts of oxalate — a compound that can stress the kidneys if consumed in large quantities.

During pregnancy and breastfeeding, there isn't enough safety information; it's best to avoid it until you've talked with your doctor or pharmacist.

Side effects, ingredient by ingredient Chaga

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Chaga.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; immunosuppressants / transplant drugs; diabetes medications.
  • For scale: 327 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking chaga, make sure to check with your doctor or pharmacist if you're on blood thinners or antiplatelet drugs (like warfarin or clopidogrel), immunosuppressants (like azathioprine or cyclosporine), or antidiabetes medications (like metformin or insulin). All three types carry a Moderate interaction risk with this product.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

If you take blood thinners, immunosuppressants, or diabetes medications, chaga isn't something to add without checking with your doctor or pharmacist first. If you have kidney concerns or are pregnant or breastfeeding, the safety data doesn't support its use.

For anyone else considering it, weigh the lack of proven effectiveness against the limited safety record.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Nov 22, 2022.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Chaga, straight from the product label.

Brand Exploding Buds
Barcode (UPC) 810012470346
Net contents 12.7 Ounce(s); 3600 Gram(s)
Market status On market
Date entered into DSLD Nov 22, 2022
DSLD ID 274844
Product type Botanical
Supplement form Powder
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Organic, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Chaga by Exploding Buds, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Gram(s)
Maximum serving Sizes:
2 Gram(s)
Servings per container
180
UPC/BARCODE
810012470346
IngredientAmount% DV
Calories10 Calorie(s)--
Total Carbohydrates2 Gram(s)1%
Chaga2 Gram(s)--

Other ingredients: None

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Formula

Chaga (Inonotus obliquus) is a mushroom that grows primarily on birch trees found in the northern temperate forests of the USA, Canada, Scandinavia (Finland, Norway, and Sweden), Russia, China, and Japan. It has a striking resemblance to burnt charcoal due to its blackish, irregular conk-shaped mass.

Formulation

Exploding Buds full-spectrum organic mushrooms are grown, dried, milled, and packaged in a state-of-the-art, cGMP compliant (registered), indoor mushroom farm located in southern California, USA. Mushrooms contain a wide variety of naturally occurring compounds, which make a great addition to a healthy lifestyle.

This product is not manufactured with milk, eggs, fish, crustacean shellfish, tree nuts, peanuts, wheat, soy, or gluten.

Certified Organic by Oregon Tilth USDA Organic

Vegan

Gluten free Non GMO

Mushroom powder Full spectrum

Aroma, color, consistency, and taste may vary.

Precautions

This product is not manufactured with milk, eggs, fish, crustacean shellfish, tree nuts, peanuts, wheat, soy, or gluten. Produced in a third-party, audited and registered cGMP compliant facility that may process other products containing these allergens or ingredients.

Warnings Keep out of reach of children.

Consult with a qualified healthcare professional prior to taking dietary supplements. Double safety sealed, with outer shrink wrap film and inner bottle freshness seal. Do not use if seals are missing or broken.

General Statements

Note: 2 grams per teaspoon is an average. Individual scooping technique may yield slightly more or less than 2 grams. This product is sold & packaged by weight, not by volume. Settling of contents occurs over time and cannot be avoided.

Questions or comments: [email protected]

24

Seals/Symbols

USDA Organic

FDA Statement of Identity

Dietary Supplement

Suggested/Recommended/Usage/Directions

Suggested Use Healthy adults, add one teaspoon (approximately 2 grams) to your favorite coffee, tea, juice, or smoothie once daily. Best when taken as directed by a qualified healthcare professional.

Storage

Store at room temperature, in a dry place. Protect product from excessive heat, freezing, humidity, and light. Improper storage conditions can cause product degradation over time.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Chaga by Exploding Buds label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Chaga label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Chaga by Exploding Buds

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Gram(s) Dosage formPowder Servings per container180 Amounts shown are per serving.

Chaga

Interacts with
327 drugs
2 Gram(s) per serving Form: Inonotus obliquus, Inonotus obliquus, Oats

Chaga is a fungus that grows mostly on birch trees and is used as a tea or supplement, mainly for immune and antioxidant support. Human evidence for i...

Chaga monograph & interactions

Other (inactive) ingredients: None. These complete the product’s ingredient list but are not active constituents.

Interaction report

Chaga by Exploding Buds Drug Interactions

Want to check YOUR meds against Chaga?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
327Drugs
327 Moderate

Ingredients driving the most interactions

Chaga 327

Individual Drug Interactions

The ingredients in Chaga interact with 327 drugs. Click any drug to see the details.

1 of the 1 ingredient in Chaga interact with drugs. Each result below shows which ingredient is responsible. Chaga

Each ingredient & the kinds of drugs it affects

For each ingredient in Chaga with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Chaga3 drug types · 327 drugs

Anticoagulant/Antiplatelet Drugs

Theoretically, chaga may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
In vitro and animal research suggests that chaga extract can inhibit platelet aggregation. This effect has not been reported in humans.

Likelihood Possible Evidence D
Antidiabetes Drugs

Theoretically, taking chaga with antidiabetes drugs might increase the risk of hypoglycemia.
Animal research suggests that chaga might decrease blood glucose levels and increase insulin levels. This has not been reported in humans.

Likelihood Possible Evidence D
Immunosuppressants

Theoretically, chaga might interfere with immunosuppressive therapy.
In vitro research suggests that certain constituents of chaga stimulate immune function. This has not been reported in humans.

Likelihood Possible Evidence D
Chaga full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Chaga, from the product label.

Exploding Buds

See all Exploding Buds products
Name
Simple Brands Group, LLC
Street Address
120 Newport Center Drive
City
Newport Beach
State
CA
ZipCode
92660
Web Address
explodingbuds.com
Pharmacist Counseling Corner

Chaga by Exploding Buds: Common Questions

Does Chaga by Exploding Buds interact with any medications?
Yes. Based on its ingredients, Chaga has a known interaction with 327 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Chaga contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take chaga if I'm pregnant or breastfeeding?
No — there isn't enough safety information to know either way. It's best to avoid it during pregnancy and while breastfeeding. Talk with your doctor or pharmacist about whether it's right for you.
What's chaga, exactly?
Chaga is a fungus that grows on birch trees. It's traditionally been used in teas and foods, especially in parts of Asia and Europe.
Does chaga actually work for heart disease or diabetes?
We don't have reliable human evidence yet to say whether it works for either. The data is insufficient to rate it for cardiovascular disease, diabetes, or COVID-19.
What's the kidney issue with chaga?
Chaga contains high amounts of oxalate, a compound that can stress the kidneys if you consume too much. There have been two cases of kidney failure and one case of kidney damage linked to heavy chaga use, so it's something to be aware of if you use it regularly or in large amounts.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Chaga label
Go deeper

The Full Monographs Behind Chaga’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Chaga

Interacts with 327 drugs

Chaga is a fungus that grows mostly on birch trees and is used as a tea or supplement, mainly for immune and antioxidant support. Human evidence for its benefits is very limited, and it may...

Read the full Chaga monograph →
Sources

Sources & How We Checked

Chaga's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 9 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Chaga 9 references
  1. Sun JE, Ao ZH, Lu ZM, et al. Antihyperglycemic and antilipidperoxidative effects of dry matter of culture broth of Inonotus obliquus in submerged culture on normal and alloxan-diabetes mice. J Ethnopharmacol 2008;118(1):7-13. PubMed
  2. Hyun KW, Jeong SC, Lee DH, et al. Isolation and characterization of a novel platelet aggregation inhibitory peptide from the medicinal mushroom, Inonotus obliquus. Peptides 2006;27(6):1173-8. PubMed
  3. Kim YO, Han SB, Lee HW, et al. Immuno-stimulating effect of the endo-polysaccharide produced by submerged culture of Inonotus obliquus. Life Sci 2005;77(19):2438-56. PubMed
  4. Kikuchi Y, Seta K, Ogawa Y, et al. Chaga mushroom-induced oxalate nephropathy. Clin Nephrol 2014;81(6):440-4. PubMed
  5. Lee S, Lee HY, Park Y, et al. Development of end stage renal disease after long-term ingestion of chaga mushroom: case report and review of literature. J Korean Med Sci. 2020;35(19):e122.
  6. Kwon O, Kim Y, Paek JH, et al. Chaga mushroom-induced oxalate nephropathy that clinically manifested as nephrotic syndrome: A case report. Medicine (Baltimore) 2022;101(10):e28997. PubMed
  7. Su L, Xin C, Yang J, et al. A polysaccharide from Inonotus obliquus ameliorates intestinal barrier dysfunction in mice with type 2 diabetes mellitus. Int J Biol Macromol 2022;214:312-323. PubMed
  8. Chen S, Ma Y, Li H, et al. Anti-diabetic e?ects of Inonotus obliquus extract in high fat diet combined streptozotocin-induced type 2 diabetic mice. Nutr Hosp 2022;39(6):1256-1263. PubMed
  9. Ye X, Wu K, Xu L, et al. Methanol extract of Inonotus obliquus improves type 2 diabetes mellitus through modifying intestinal flora. Front Endocrinol (Lausanne) 2023;13:1103972. PubMed

See these in context on the Chaga monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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