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Dietary supplement

Chestnut Bud Flower Essence Ingredients & Drug Interactions

by Flower Essence Services

Chestnut Bud Flower Essence label
See full label image
Liquid Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 23, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Chestnut Bud Flower Essence against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Chestnut Bud Flower Essence is a dietary supplement by Flower Essence Services with 1 active ingredient. Its ingredients are commonly taken for chronic venous insufficiency, leg swelling and heaviness, varicose veins.Based on those ingredients, 122 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are infusion (1:6000) of Aesculus hippocastanum. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Chestnut Bud Flower Essence by Flower Essence Services

Ask about any prescription or over-the-counter medication and we check it for interactions with Chestnut Bud Flower Essence by Flower Essence Services — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Chestnut Bud Flower Essence by Flower Essence Services

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 16, 2026

What’s inside

Low disclosure
Ingredient Transparency · database check
Low

Most active ingredients don't disclose an individual amount — you can't tell how much of each you're getting.

Why this rating?
  • The label discloses an exact amount for 0 of its 1 active ingredient.

This product contains one active ingredient: an infusion of horse chestnut (Aesculus hippocastanum) at a 1:6000 dilution — meaning one part plant material steeped in 6,000 parts liquid. The remaining ingredients are water and brandy, which serve as the liquid base and preservative.

Horse chestnut has been used traditionally for circulatory concerns. The dilution in this flower essence is much more attenuated than the concentrated seed extracts used in clinical studies, so the amount of active compound you receive per dose is very small.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed

This product doesn't appear to be marketed for a specific use, so we graded Horse Chestnut's overall clinical evidence instead.

Moderate

Some clinical evidence supports Horse Chestnut for:

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.
  • Since the label doesn't commit to one use, we graded the ingredient's overall clinical evidence instead.
  • On file: Chronic venous insufficiency (CVI) — rated "Possibly Effective" (Natural Medicines).

For chronic venous insufficiency (poor circulation in the legs), horse chestnut is rated possibly effective — meaning there's some evidence it may help, but we don't have enough reliable data to be certain. For hemorrhoids, irritable bowel syndrome, and kidney stones, the evidence we hold is insufficient to say whether it works or not.

Keep in mind that this product is a highly diluted flower essence, not a concentrated seed extract like those tested in the studies behind those ratings. How much of that benefit carries over to a 1:6000 dilution isn't clear from the data we hold.

The evidence, ingredient by ingredient Horse Chestnut

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Horse chestnut seed extract (properly processed to remove toxic compounds) is generally well tolerated when taken by mouth, though some people report dizziness, upset stomach, headache, or itching. Topical use has no reported adverse effects.

However, complete safety data hasn't been gathered, and raw or inadequately processed plant parts are toxic. During pregnancy, there isn't enough safety information — the data advises against use.

The same goes for breastfeeding: safety hasn't been established, so it's best avoided. If you're pregnant, planning to become pregnant, or breastfeeding, talk with your doctor or pharmacist before taking this product.

Side effects, ingredient by ingredient Horse Chestnut

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Horse Chestnut.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs.
  • For scale: 122 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

If you take blood thinners or antiplatelet drugs like warfarin, aspirin, or clopidogrel, double-check with your doctor or pharmacist before starting this product — horse chestnut may increase your bleeding risk. No other medication interactions are documented for the ingredients we could check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFormula with limited ingredient disclosure with some supporting evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.

Chestnut Bud Flower Essence might be worth considering if you're interested in traditional flower remedies for circulatory concerns, but the evidence for its effectiveness in humans is limited. If you take blood thinners or antiplatelet drugs, check with your doctor or pharmacist first — horse chestnut may increase bleeding risk.

Avoid it if you're pregnant or breastfeeding.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jan 24, 2014.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Chestnut Bud Flower Essence, straight from the product label.

Brand Flower Essence Services
Barcode (UPC) 782932220076
Net contents 0.25 fl. Oz.; 7.5 mL
Market status On market
Date entered into DSLD Jan 24, 2014
DSLD ID 29801
Product type Botanical
Supplement form Liquid
Dietary claims / uses No Claim
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Chestnut Bud Flower Essence by Flower Essence Services, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
4 Drop(s)
Maximum serving Sizes:
4 Drop(s)
UPC/BARCODE
782932220076
IngredientAmount% DV
infusion (1:6000) of Aesculus hippocastanum0 NP--

Other ingredients: Water, brandy

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)

BEST BY 02/2021 110203

Demeter-certified Biodynamic(R)

Suggested/Recommended/Usage/Directions

Suggested use: four drops, four times daily

Seals/Symbols

Healingherbs(C)

DEMETER

FDA Statement of Identity

herbal supplement

Formulation

Made with Organic ingredients Certified by Stellar Cert. Services

General

110203

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Chestnut Bud Flower Essence by Flower Essence Services label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Chestnut Bud Flower Essence label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Chestnut Bud Flower Essence by Flower Essence Services

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size4 Drop(s) Dosage formLiquid Amounts shown are per serving.

Infusion (1:6000) of Aesculus hippocastanum

Interacts with
122 drugs
0 NP per serving

Horse chestnut seed extract is most often used for chronic venous insufficiency, where standardized products may help reduce leg swelling, pain, and h...

Infusion (1:6000) of Aesculus hippocastanum monograph & interactions

Other (inactive) ingredients: Water, Brandy. These complete the product’s ingredient list but are not active constituents.

Interaction report

Chestnut Bud Flower Essence by Flower Essence Services Drug Interactions

Want to check YOUR meds against Chestnut Bud Flower Essence?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
122Drugs
122 Moderate

Ingredients driving the most interactions

infusion (1:6000) of Aesculus hippocastanum 122

Individual Drug Interactions

The ingredients in Chestnut Bud Flower Essence interact with 122 drugs. Click any drug to see the details.

1 of the 1 ingredient in Chestnut Bud Flower Essence interact with drugs. Each result below shows which ingredient is responsible. infusion (1:6000) of Aesculus hippocastanum

Each ingredient & the kinds of drugs it affects

For each ingredient in Chestnut Bud Flower Essence with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

infusion (1:6000) of Aesculus hippocastanum1 drug type · 122 drugs

Anticoagulant/Antiplatelet Drugs

Horse chestnut may have antiplatelet effects and may increase the risk of bleeding if used with anticoagulant or antiplatelet drugs.
Horse chestnut contains the constituent esculin which has been shown to have antithrombotic effects. Therefore, horse chestnut might have antiplatelet effects. This has not been shown in humans.

Likelihood Possible Evidence D
infusion (1:6000) of Aesculus hippocastanum full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Chestnut Bud Flower Essence, from the product label.

Flower Essence Services

See all Flower Essence Services products
Phone Number
800-548-0075
Pharmacist Counseling Corner

Chestnut Bud Flower Essence by Flower Essence Services: Common Questions

Does Chestnut Bud Flower Essence by Flower Essence Services interact with any medications?
Yes. Based on its ingredients, Chestnut Bud Flower Essence has a known interaction with 122 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Chestnut Bud Flower Essence contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Is this safe to take while pregnant or breastfeeding?
No. The safety data advises against use during pregnancy, and safety hasn't been established for breastfeeding either. Talk with your doctor or pharmacist if you're pregnant, planning to become pregnant, or nursing.
What are the most common side effects?
The horse chestnut in this product is highly diluted, so serious side effects are unlikely. However, the concentrated extracts studied in safety data show dizziness, upset stomach, headache, or itching in some people — though these are uncommon.
Does horse chestnut actually work for circulation?
For chronic venous insufficiency (poor leg circulation), there's some evidence horse chestnut may help — that's why it's rated possibly effective. For other uses like hemorrhoids or IBS, we don't have enough reliable evidence to say either way.
Why is this product so diluted?
This is a flower essence, which by design uses a high dilution of the plant material in liquid. Concentrated seed extracts — the form studied most in research — contain much more active ingredient per dose.
Can I take this with my blood thinner?
Not without checking first. Horse chestnut has compounds that may thin your blood further, which could raise your bleeding risk. Talk with your doctor or pharmacist about whether it's safe for you alongside your specific medication.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Chestnut Bud Flower Essence label
Go deeper

The Full Monographs Behind Chestnut Bud Flower Essence’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Horse Chestnut

Interacts with 122 drugs

Horse chestnut seed extract is most often used for chronic venous insufficiency, where standardized products may help reduce leg swelling, pain, and heaviness. Raw, unprocessed horse chestnu...

Read the full Horse Chestnut monograph →
Sources

Sources & How We Checked

Chestnut Bud Flower Essence's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 21 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Horse Chestnut 21 references
  1. Blumenthal M, ed. The Complete German Commission E Monographs: Therapeutic Guide to Herbal Medicines. Trans. S. Klein. Boston, MA: American Botanical Council, 1998.
  2. Ellenhorn MJ, et al. Ellenhorn's Medical Toxicology: Diagnoses and Treatment of Human Poisoning. 2nd ed. Baltimore, MD: Williams & Wilkins, 1997.
  3. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  4. Brinker F. Herb Contraindications and Drug Interactions. 2nd ed. Sandy, OR: Eclectic Medical Publications, 1998.
  5. Greeske K, Pohlmann BK. Horse chestnut seed extract-an effective therapy principle in general practice. Drug therapy of chronic venous insufficiency. Fortschr Med 1996;114:196-200.
  6. Robbers JE, Tyler VE. Tyler's Herbs of Choice: The Therapeutic Use of Phytomedicinals. New York, NY: The Haworth Herbal Press, 1999.
  7. Takegoshi K, Tohyama T, Okuda K, et al. A case of Venoplant-induced hepatic injury. Gastroenterol Jpn 1986;21:62-5.
  8. Jaspersen-Schib R, Theus L, Guirguis-Oeschger M, et al. [Serious plant poisonings in Switzerland 1966-1994. Case analysis from the Swiss Toxicology Information Center]. Schweiz Med Wochenschr 1996;126:1085-98.
  9. Popp W, Horak F, Jager S, et al. Horse chestnut (Aesculus hippocastanum) pollen: a frequent cause of allergic sensitization in urban children. Allergy 1992;47:380-3.
  10. Diaz-Perales A, Collada C, Blanco C, et al. Cross-reactions in the latex-fruit syndrome: A relevant role of chitinases but not of complex asparagine-linked glycans. J Allergy Clin Immunol 1999;104:681-7. PubMed
  11. Blanco C, Diaz-Perales A, Collada C, et al. Class I chitinases as potential panallergens involved in the latex-fruit syndrome. J Allergy Clin Immunol 1999;103:507-13. PubMed
  12. Comaish JS, Kersey PJ. Contact dermatitis to extract of horse chestnut (esculin). Contact Dermatitis 1980;6:150-1. PubMed
  13. Pittler MH, Ernst E. Horse chestnut seed extract for chronic venous insufficiency (Cochrane Review). In: The Cochrane Library, Issue 3, 2004. Chichester, UK: John Wiley & Sons, Ltd. PubMed
  14. Ottillinger, B. and Greeske, K. Rational therapy of chronic venous insufficiency--chances and limits of the therapeutic use of horse-chestnut seeds extract. BMC.Cardiovasc.Disord. 2001;1(1):5. PubMed
  15. Pittler, M. H. and Ernst, E. Horse chestnut seed extract for chronic venous insufficiency. Cochrane.Database.Syst.Rev. 2004;(2):CD003230. PubMed
  16. Fang, Y., Zhao, L., Yan, F., Xia, X., Xu, D., and Cui, X. Escin improves sperm quality in male patients with varicocele-associated infertility. Phytomedicine. 2010;17(3-4):192-196. PubMed
  17. De Smet, P. A., Van den Eertwegh, A. J., Lesterhuis, W., and Stricker, B. H. Hepatotoxicity associated with herbal tablets. BMJ 7-13-1996;313(7049):92.
  18. Rehn, D., Unkauf, M., Klein, P., Jost, V., and Lucker, P. W. Comparative clinical efficacy and tolerability of oxerutins and horse chestnut extract in patients with chronic venous insufficiency. Arzneimittelforschung 1996;46(5):483-487.
  19. Edem E, Kahyaoglu B, Çakar MA. Acute Effusive Pericarditis due to Horse Chestnut Consumption. Am J Case Rep. 2016;17:305-8. PubMed
  20. Costa Santos D, Lérias G, Madruga I. Drug-induced Liver Injury Due to a Horse Chestnut Dietary Supplement. Eur J Case Rep Intern Med 2021;8(3):002389. PubMed
  21. Yi HY, Lee JY. Poisoning due to consumption of horse chestnut seed. Clin Exp Emerg Med 2021;8(4):333-335. PubMed

See these in context on the Horse Chestnut monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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