Chewable Coenzyme Q10 100 mg Ingredients & Drug Interactions
by Vitabase
What is this page for?
First and foremost: checking Chewable Coenzyme Q10 100 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Chewable Coenzyme Q10 100 mg is a dietary supplement by Vitabase with 1 active ingredient. Its ingredients are commonly taken for heart health, statin-related muscle aches, migraine prevention.Based on those ingredients, 198 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Coenzyme Q 10. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against Chewable Coenzyme Q10 100 mg by Vitabase
Ask about any prescription or over-the-counter medication and we check it for interactions with Chewable Coenzyme Q10 100 mg by Vitabase — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
Ask the Pharmacist
A licensed pharmacist will answer your question by email — free, usually within 24 hours.
Got it — thank you!
A licensed pharmacist will answer within 24 hours. Keep an eye on your email (worth checking spam, just in case).
HelloPharmacist Scorecard of Chewable Coenzyme Q10 100 mg by Vitabase
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Full disclosure
This product contains one active ingredient: coenzyme Q10 at 100 mg per chewable tablet. Coenzyme Q10 (also called CoQ10) is a substance your body makes naturally and stores in your cells — it plays a role in energy production and acts as an antioxidant.
The product also includes several inactive ingredients — xylitol, sorbitol, orange and pineapple juice crystals, xanthan gum, natural flavors, vitamin E, mannitol, citric acid, orange peel powder, Swerve, and glycyrrhizinic acid — which are the sweeteners, binders, and flavorings that make it chewable.
Does it work?
Strong evidence
The evidence for coenzyme Q10 varies by condition. It's rated likely effective for correcting coenzyme Q10 deficiency.
For fibromyalgia, migraine headache, congestive heart failure (CHF), and diabetic neuropathy, the data is rated possibly effective — meaning there's some promising research, but more evidence is needed to be certain. We hold no other effectiveness ratings for this ingredient in our data.
How safe is it?
Well-documented data
Coenzyme Q10 is generally well tolerated when taken as directed. In clinical trials, no serious side effects were reported.
The most common problems are mild gastrointestinal issues — appetite suppression, diarrhea, heartburn, nausea, and vomiting — though these occur in less than 1% of people taking it. Headache, dizziness, and insomnia have been reported in some studies.
A small number of trial participants reported skin itching or allergic rash. For pregnancy, the safety data advises against use unless your doctor advises otherwise.
For breastfeeding, safety hasn't been well studied — check with your doctor before using.
Meds to double-check
Moderate interaction found
Before you take this, check with your pharmacist if you're on warfarin (a blood thinner) — coenzyme Q10 can reduce its effectiveness. Also flag any chemotherapy drugs you're taking, especially alkylating agents like cyclophosphamide, and blood pressure medications, since coenzyme Q10 may interact with all three.
The bottom line
Scorecard at a glanceFully disclosed formula with strong clinical evidence behind its ingredients' uses. Moderate medication interactions have been identified, and safety information is well characterized.
Coenzyme Q10 may help with energy production and some conditions like migraines and heart failure, though the evidence is strongest for treating a deficiency. If you take warfarin or chemotherapy, you need to talk to your pharmacist before starting this — it can interfere with how those drugs work.
It's generally well tolerated, but watch for mild stomach upset.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Mar 23, 2012.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Chewable Coenzyme Q10 100 mg, straight from the product label.
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Chewable Coenzyme Q10 100 mg by Vitabase, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Coenzyme Q 10 | 100 mg | -- |
Other ingredients: Xylitol, Sorbitol, Orange juice crystals, Xanthan Gum, natural orange and pineapple flavors, pineapple juice crystals, Vitamin E, Mannitol, Citric Acid, orange peel powder, Swerve(TM), Glycyrrhizinic Acid
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions
Suggested Use: As a dietary supplement, adults chew one (1) tablet daily with meals or as directed by a health care professional.
Storage
Store in a cool, dry place and away from direct light.
General Statements
Orange Flavor
Vitabase uses only high quality ingredients.
QUALITY AND POTENCY GUARANTEED. MADE IN THE U.S.A.
FDA Statement of Identity
DIETARY SUPPLEMENT
Formula
Contains soy.
Precautions
Keep out of reach of children.
Formulation
Contains No Added salt, yeast, dairy, wheat, gluten, corn, preservatives, artificial colors or flavors.
Seals/Symbols
Vb
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Chewable Coenzyme Q10 100 mg by Vitabase label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Chewable Coenzyme Q10 100 mg by Vitabase
This is the 1 active ingredient this product is made of. Select it to open its full monograph.
Serving size1 Tablet(s) Dosage formTablet Or Pill Amounts shown are per serving.
Coenzyme Q 10
Interacts with198 drugs
CoQ10 is a vitamin-like substance your body makes naturally that helps cells produce energy and acts as an antioxidant. It is generally well tolerated...
Coenzyme Q 10 monograph & interactionsOther (inactive) ingredients: Xylitol, Sorbitol, Orange juice crystals, Xanthan Gum, Natural orange and pineapple flavors, Pineapple juice crystals, Vitamin E, Mannitol, Citric Acid, Orange peel powder, Swerve(TM), Glycyrrhizinic Acid. These complete the product’s ingredient list but are not active constituents.
Chewable Coenzyme Q10 100 mg by Vitabase Drug Interactions
HelloPharmacist Interaction Report
Vitabase Chewable Coenzyme Q10 100 mg does interact with a few important medication types.
The most serious concern is with warfarin (Coumadin), a blood thinner. Coenzyme Q10 has chemical properties similar to vitamin K, which can reduce warfarin's ability to prevent clots.
Four cases of reduced warfarin effectiveness linked to coenzyme Q10 have been reported, though more research is needed.
Read the full breakdown — every affected drug type, severity by severity
Coenzyme Q10 may also reduce the activity of alkylating chemotherapy drugs — a class of cancer medications that work by generating free radicals to damage tumor cells. Its antioxidant effects could theoretically protect cancer cells from these drugs' intended action.
Additionally, it might add to the blood-pressure-lowering effects of antihypertensive medications, though clinical evidence on this is mixed. Altogether, these interactions span 198 individual medications.
If you take warfarin, any chemotherapy, or blood pressure medication, check your exact drugs with the search tool on this page before you start.
Check your own medications below · Editorial policy · How we use AI
Want to check YOUR meds against Chewable Coenzyme Q10 100 mg?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in Chewable Coenzyme Q10 100 mg interact with 198 drugs. Click any drug to see the details.
1 of the 1 ingredient in Chewable Coenzyme Q10 100 mg interact with drugs. Each result below shows which ingredient is responsible. Coenzyme Q 10
AmilorideAmilamont, Midamor
How Amiloride interacts with Chewable Coenzyme Q10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q 10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q 10 + Amiloride interactionAmiloride, HydrochlorothiazideAmil-Co, Amilzide, Moduret 25, Moduretic
How Amiloride, Hydrochlorothiazide interacts with Chewable Coenzyme Q10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q 10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q 10 + Amiloride, Hydrochlorothiazide interactionAmlodipineNorliqva
How Amlodipine interacts with Chewable Coenzyme Q10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q 10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q 10 + Amlodipine interactionAmlodipine BenzoateKaterzia
How Amlodipine Benzoate interacts with Chewable Coenzyme Q10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q 10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q 10 + Amlodipine Benzoate interactionAmlodipine BesilateIstin
How Amlodipine Besilate interacts with Chewable Coenzyme Q10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q 10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q 10 + Amlodipine Besilate interactionAmlodipine BesylateNorvasc
How Amlodipine Besylate interacts with Chewable Coenzyme Q10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q 10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q 10 + Amlodipine Besylate interactionAmlodipine Besylate, BenazeprilLotrel
How Amlodipine Besylate, Benazepril interacts with Chewable Coenzyme Q10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q 10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q 10 + Amlodipine Besylate, Benazepril interactionAmlodipine, CelecoxibConsensi
How Amlodipine, Celecoxib interacts with Chewable Coenzyme Q10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q 10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q 10 + Amlodipine, Celecoxib interactionAmmonium ChlorideAmmonium Chloride
How Ammonium Chloride interacts with Chewable Coenzyme Q10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q 10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q 10 + Ammonium Chloride interactionAprocitentanTryvio
How Aprocitentan interacts with Chewable Coenzyme Q10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q 10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q 10 + Aprocitentan interactionAtenololAtenix, Tenormin
How Atenolol interacts with Chewable Coenzyme Q10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q 10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q 10 + Atenolol interactionAtenolol, ChlortalidoneAtenixCo, Tenoret 50, Totaretic
How Atenolol, Chlortalidone interacts with Chewable Coenzyme Q10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q 10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q 10 + Atenolol, Chlortalidone interactionAtenolol, ChlorthalidoneTenoretic
How Atenolol, Chlorthalidone interacts with Chewable Coenzyme Q10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q 10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q 10 + Atenolol, Chlorthalidone interactionAzilsartanEdarbi
How Azilsartan interacts with Chewable Coenzyme Q10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q 10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q 10 + Azilsartan interactionAzilsartan, ChlorthalidoneEdarbyclor
How Azilsartan, Chlorthalidone interacts with Chewable Coenzyme Q10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q 10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q 10 + Azilsartan, Chlorthalidone interactionBenazeprilLotensin
How Benazepril interacts with Chewable Coenzyme Q10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q 10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q 10 + Benazepril interactionBenazepril, HydrochlorothiazideLotensin HCT
How Benazepril, Hydrochlorothiazide interacts with Chewable Coenzyme Q10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q 10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q 10 + Benazepril, Hydrochlorothiazide interactionBendroflumethiazideAprinox, Naturetin, Neo-NaClex
How Bendroflumethiazide interacts with Chewable Coenzyme Q10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q 10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q 10 + Bendroflumethiazide interactionBendroflumethiazide, NadololCorzide
How Bendroflumethiazide, Nadolol interacts with Chewable Coenzyme Q10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q 10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q 10 + Bendroflumethiazide, Nadolol interactionBendroflumethiazide, Rauwolfia SerpentinaRauzide
How Bendroflumethiazide, Rauwolfia Serpentina interacts with Chewable Coenzyme Q10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q 10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q 10 + Bendroflumethiazide, Rauwolfia Serpentina interactionBenzthiazideExna
How Benzthiazide interacts with Chewable Coenzyme Q10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q 10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q 10 + Benzthiazide interactionBetaxololBetoptic, Kerlone
How Betaxolol interacts with Chewable Coenzyme Q10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q 10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q 10 + Betaxolol interactionBisoprololZebeta
How Bisoprolol interacts with Chewable Coenzyme Q10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q 10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q 10 + Bisoprolol interactionBisoprolol, HydrochlorothiazideZiac
How Bisoprolol, Hydrochlorothiazide interacts with Chewable Coenzyme Q10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q 10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q 10 + Bisoprolol, Hydrochlorothiazide interactionBosentanTracleer
How Bosentan interacts with Chewable Coenzyme Q10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q 10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q 10 + Bosentan interactionBumetanideBurinex
How Bumetanide interacts with Chewable Coenzyme Q10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q 10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q 10 + Bumetanide interactionBumetanide (iv)Bumex
How Bumetanide (iv) interacts with Chewable Coenzyme Q10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q 10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q 10 + Bumetanide (iv) interactionBumetanide (oral)Bumex
How Bumetanide (oral) interacts with Chewable Coenzyme Q10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q 10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q 10 + Bumetanide (oral) interactionCandesartan CilexetilAmias, Atacand
How Candesartan Cilexetil interacts with Chewable Coenzyme Q10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q 10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q 10 + Candesartan Cilexetil interactionCandesartan Cilexetil, HydrochlorothiazideAtacand HCT
How Candesartan Cilexetil, Hydrochlorothiazide interacts with Chewable Coenzyme Q10 100 mg — through 1 ingredient. Tap an ingredient for the detail:
Coenzyme Q 10Antihypertensive Drugs Minor
Interaction Summary
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Read the full Coenzyme Q 10 + Candesartan Cilexetil, Hydrochlorothiazide interactionEach ingredient & the kinds of drugs it affects
For each ingredient in Chewable Coenzyme Q10 100 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.
Coenzyme Q 10
Alkylating Agents
Coenzyme Q10 has antioxidant effects. Theoretically, this may reduce the activity of chemotherapy drugs that generate free radicals.
Theoretically, antioxidants such as coenzyme Q10 might protect tumor cells from chemotherapeutic agents that work by inducing oxidative stress, such as alkylating agents (e.g., cyclophosphamide) and radiation therapy. The clinical importance of this interaction is unknown.
Warfarin (Coumadin)
Coenzyme Q10 is chemically similar to menaquinone and might have vitamin K-like procoagulant effects, which could decrease the effects of warfarin.
Concomitant use of coenzyme Q10 and warfarin might reduce the anticoagulant effects of warfarin. Four cases of decreased warfarin efficacy thought to be due to coenzyme Q10 have been reported. However, there is some preliminary clinical research that suggests coenzyme Q10 might not significantly decrease the effects of warfarin in patients who have a stable INR.
Antihypertensive Drugs
Theoretically, coenzyme Q10 might have additive effects with antihypertensive drugs.
Some clinical research shows that coenzyme Q10 can significantly lower blood pressure, although other studies have shown conflicting results.
Brand information
Manufacturer and brand details for Chewable Coenzyme Q10 100 mg, from the product label.
Chewable Coenzyme Q10 100 mg by Vitabase: Common Questions
Does Chewable Coenzyme Q10 100 mg by Vitabase interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
What is coenzyme Q10, and what does it do in my body?
Can I take this if I'm on blood pressure medication?
Is this product safe during breastfeeding?
What side effects might I experience?
Does coenzyme Q10 really help with heart failure?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Chewable Coenzyme Q10 100 mg is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Chewable Coenzyme Q10 100 mg’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Sources & How We Checked
Chewable Coenzyme Q10 100 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 40 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Coenzyme Q10 40 references
- Kamikawa T, Kobayashi A, Yamashita T, et al. Effects of coenzyme Q10 on exercise tolerance in chronic stable angina pectoris. Am J Cardiol 1985;56:247-51. PubMed
- Langsjoen P, Willis R, Folkers K. Treatment of essential hypertension with coenzyme Q10. Mol Aspects Med 1994;S265-72. PubMed
- Spigset O. Reduced effect of warfarin caused by ubidecarenone. Lancet 1994;334:1372-3. PubMed
- Singh RB, Niaz MA, Rastogi SS, et al. Effect of hydrosoluble coenzyme Q10 on blood pressures and insulin resistance in hypertensive patients with coronary artery disease. J Hum Hypertens 1999;13:203-8. PubMed
- Portakal O, Ozkaya O, Erden Inal M, et al. Coenzyme Q10 concentrations and antioxidant status in tissues of breast cancer patients. Clin Biochem 2000;33:279-84. PubMed
- Lund EL, Quistorff B, Spang-Thomsen M, Kristjansen PE. Effect of radiation therapy on small-cell lung cancer is reduced by ubiquinone intake. Folia Microbiol (Praha) 1998;43:505-6. PubMed
- Langsjoen PH, Langsjoen PH, Folkers K. Long-term efficacy and safety of coenzyme Q10 therapy for idiopathic dilated cardiomyopathy. Am J Cardiol 1990;65:521-3. PubMed
- Heck AM, DeWitt BA, Lukes AL. Potential interactions between alternative therapies and warfarin. Am J Health Syst Pharm 2000;57:1221-7. DOI
- Landbo C, Almdal TP. [Interaction between warfarin and coenzyme Q10]. Ugeskr Laeger 1998;160:3226-7.
- Baggio E, Gandini R, Plauncher AC, et al. Italian multicenter study on the safety and efficacy of coenzyme Q10 as adjunctive therapy in heart failure. CoQ10 Drug Surveillance Investigators. Mol Aspects Med 1994;15 Suppl:S287-94. PubMed
- Burke BE, Neuenschwander R, Olson RD. Randomized, double-blind, placebo-controlled trial of coenzyme Q10 in isolated systolic hypertension. South Med J 2001;94:1112-7. PubMed
- The Huntington Study Group. A randomized, placebo-controlled trial of coenzyme Q10 and remacemide in Huntington's disease. Neurology 2001;57:397-404.
- Hodgson JM, Watts GF, Playford DA, et al. Coenzyme Q10 improves blood pressure and glycaemic control: a controlled trial in subjects with type 2 diabetes. Eur J Clin Nutr 2002;56:1137-42. PubMed
- Singh RB, Neki NS, Kartikey K, et al. Effect of coenzyme Q10 on risk of atherosclerosis in patients with recent myocardial infarction. Mol Cell Biochem 2003;246:75-82. DOI
- Porterfield LM. Why did the response to warfarin change? RN 2000;63:107.
- Sandor PS, Di Clemente L, Coppola G, et al. Efficacy of coenzyme Q10 in migraine prophylaxis: A randomized controlled trial. Neurology 2005;64:713-5. PubMed
- Engelsen J, Nielsen JD, Winther K. Effect of coenzyme Q10 and Ginkgo biloba on warfarin dosage in stable, long-term warfarin treated outpatients. A randomised, double blind, placebo-crossover trial. Thromb Haemost 2002;87:1075-6. DOI
- Berman M, Erman A, Ben-Gal T, et al. Coenzyme Q10 in patients with end-stage heart failure awaiting cardiac transplantation: a randomized, placebo-controlled study. Clin Cardiol 2004;27:295–9. PubMed
- Storch A, Jost WH, Vieregge P, et al. Randomized, double-blind, placebo-controlled trial on symptomatic effects of coenzyme Q10 in Parkinson disease. Arch Neurol 2007;64:938-44. DOI
- Digiesi V, Cantini F, Oradei A, et al. Coenzyme Q10 in essential hypertension. Mol Aspects Med 1994;15 Suppl:s257-63. PubMed
- Yamagami T, Takagi M, Akagami H, et al. Effect of coenzyme Q10 on essential hypertension, a double blind controlled study. In: Folkers KA, Yamamura Y, eds. Biomedical and Clinical Aspects of Coenzyme Q, Vol. 5. Amsterdam: Elsevier Science Publications, 19
- Ho MJ, Bellusci A, Wright JM. Blood pressure lowering efficacy of coenzyme Q10 for primary hypertension (review). Cochrane Database Syst Rev 2009;(4):CD007435. PubMed
- Rosenfeldt, F. L., Haas, S. J., Krum, H., Hadj, A., Ng, K., Leong, J. Y., and Watts, G. F. Coenzyme Q10 in the treatment of hypertension: a meta-analysis of the clinical trials. J Hum.Hypertens. 2007;21(4):297-306. PubMed
- Stamelou, M., Reuss, A., Pilatus, U., Magerkurth, J., Niklowitz, P., Eggert, K. M., Krisp, A., Menke, T., Schade-Brittinger, C., Oertel, W. H., and Hoglinger, G. U. Short-term effects of coenzyme Q10 in progressive supranuclear palsy: a randomized, place DOI
- Keogh A, Fenton S, Leslie C, et al. Randomised double-blind, placebo-controlled trial of coenzyme Q, therapy in class II and III systolic heart failure. Heart Lung Circ. 2003;12:135-41.
- Gane, E. J., Weilert, F., Orr, D. W., Keogh, G. F., Gibson, M., Lockhart, M. M., Frampton, C. M., Taylor, K. M., Smith, R. A., and Murphy, M. P. The mitochondria-targeted anti-oxidant mitoquinone decreases liver damage in a phase II study of hepatitis C
- Lynch, D. R., Perlman, S. L., and Meier, T. A phase 3, double-blind, placebo-controlled trial of idebenone in friedreich ataxia. Arch Neurol. 2010;67(8):941-947. PubMed
- Young, J. M., Florkowski, C. M., Molyneux, S. L., McEwan, R. G., Frampton, C. M., Nicholls, M. G., Scott, R. S., and George, P. M. A randomized, double-blind, placebo-controlled crossover study of coenzyme Q10 therapy in hypertensive patients with the me
- Ishiyama, T., Morita, Y., Toyama, S., Yamagami, T., and Tsukamoto, N. A clinical study of the effect of coenzyme Q on congestive heart failure. Jpn.Heart J 1976;17(1):32-42. PubMed
- Matthews, P. M., Ford, B., Dandurand, R. J., Eidelman, D. H., O'Connor, D., Sherwin, A., Karpati, G., Andermann, F., and Arnold, D. L. Coenzyme Q10 with multiple vitamins is generally ineffective in treatment of mitochondrial disease. Neurology 1993;43(5
- Malm, C., Svensson, M., Sjoberg, B., Ekblom, B., and Sjodin, B. Supplementation with ubiquinone-10 causes cellular damage during intense exercise. Acta Physiol Scand. 1996;157(4):511-512. PubMed
- Singh, R. B., Wander, G. S., Rastogi, A., Shukla, P. K., Mittal, A., Sharma, J. P., Mehrotra, S. K., Kapoor, R., and Chopra, R. K. Randomized, double-blind placebo-controlled trial of coenzyme Q10 in patients with acute myocardial infarction. Cardiovasc. PubMed
- Digiesi V, Cantini F, and Brodbeck B. Effect of coenzyme Q10 on essential arterial hypertension. Current Therapeutic Research 1990;47(5):841-845.
- Parkinson Study Group QE3 Investigators, Beal MF, Oakes D, et al. A randomized clinical trial of high-dosage coenzyme Q10 in early Parkinson disease: no evidence of benefit. JAMA Neurol. 2014;71(5):543-52.
- Alehagen U, Johansson P, Bjornstedt M, et al. Cardiovascular mortality and N-terminal-proBNP reduced after combined selenium and coenzyme Q10 supplementation: A 5-year prospective randomized double-blind placebo-controlled trial among elderly Swedish citi
- Ho MJ, Li EC, Wright JM. Blood pressure lowering efficacy of coenzyme Q10 for primary hypertension. Cochrane Database Syst Rev. 2016 Mar 3;3:CD007435. doi: 10.1002/14651858.CD007435.pub3. PubMed
- Tabrizi R, Akbari M, Sharifi N, Lankarani KB, Moosazadeh M, Kolahdooz F, et al. The effects of coenzyme Q10 supplementation on blood pressures among patients with metabolic diseases: a systematic review and meta-analysis of randomized controlled trials. PubMed
- Tsai IC, Hsu CW, Chang CH, Tseng PT, Chang KV. Effectiveness of coenzyme Q10 supplementation for reducing fatigue: A systematic review and meta-analysis of randomized controlled trials. Front Pharmacol 2022;13:883251. PubMed
- Yaghini O, Hoseini N, Ghazavi MR, et al. A comparative study on the efficacy of coenzyme Q10 and amitriptyline in the prophylactic treatment of migraine headaches in children: A randomized controlled trial. Adv Biomed Res 2022;11:43. PubMed
- Hansen KS, Mogensen TH, Agergaard J, et al. High-dose coenzyme Q10 therapy versus placebo in patients with post COVID-19 condition: A randomized, phase 2, crossover trial. Lancet Reg Health Eur 2022. PubMed
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC