Chewable Digest Orange Flavor Ingredients & Drug Interactions
by Enzymedica
What is this page for?
First and foremost: checking Chewable Digest Orange Flavor against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
Chewable Digest Orange Flavor is a dietary supplement by Enzymedica with 15 active ingredients. Its ingredients are commonly taken for digestion and bloating, muscle soreness and exercise recovery, inflammation and swelling.We don’t currently list a known drug interaction for its mapped ingredients — but that doesn’t guarantee none exist, so always confirm with your pharmacist.
HelloPharmacist Scorecard of Chewable Digest Orange Flavor by Enzymedica
Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.
What’s inside
Low disclosure
This chewable has 15 active digestive enzymes. The ones we have data on are protease (breaks down protein), lipase (breaks down fat), and lactase (breaks down milk sugar).
It also contains phytase and several other enzymes — amylase, cellulase, invertase, glucoamylase, xylanase, pectinase, maltase, beta-glucanase, hemicellulase, and alpha-galactosidase — that help your body digest different foods. L-leucine is an amino acid also included.
The tablet also has inactive ingredients like tapioca dextrose, citric acid, and natural orange flavor.
Does it work?
Strong evidence
The evidence for most of these enzymes isn't established in the data we hold. Lactase is the one exception — it's rated effective for lactose intolerance.
For the others, including protease and lipase, the evidence is insufficient to say whether they work for digestive complaints like indigestion or inflammatory bowel disease. That doesn't mean they don't help; it means the research backing them isn't solid enough yet to rate them.
How safe is it?
Well-documented data
Protease, lipase, lactase, and phytase are generally well tolerated by most adults. Protease should be avoided in pregnancy unless your doctor prescribes it; there's little safety data during breastfeeding.
Lipase has little data in pregnancy and limited study while breastfeeding — talk with your doctor first. Lactase is likely safe in pregnancy and acts only in your gut.
Phytase has not enough reliable safety information in pregnancy or breastfeeding, so avoid it unless your doctor advises otherwise. Rarely, people can have allergic reactions to protease or lactase, particularly those with occupational exposure to enzyme powders.
If you have serious digestive conditions, use these enzymes only under medical guidance.
Meds to double-check
No known interactions
No interactions are documented in our data for the ingredients we could check. If you take prescription medications, use the search tool on this page to verify your specific drugs before you start.
The bottom line
Scorecard at a glanceFormula with limited ingredient disclosure with clinical evidence supporting its stated purpose. No medication interactions are currently documented, and safety information is well characterized.
This is a broad-spectrum digestive enzyme blend. It's a reasonable choice if you're looking to support digestion, especially if you have trouble breaking down milk sugar — lactase has solid evidence for that.
If you're pregnant, breastfeeding, or have a serious gut condition, talk with your doctor or pharmacist first to make sure it's right for you.
Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI
Assessment coverage: 4 of 15 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated May 21, 2025.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about Chewable Digest Orange Flavor, straight from the product label.
| Brand | Enzymedica |
|---|---|
| Barcode (UPC) | 670480130421 |
| Net contents | 30 Chewable Tablet(s) |
| Market status | On market |
| Date entered into DSLD | May 21, 2025 |
| DSLD ID | 328911 |
| Product type | Other Combinations |
| Supplement form | Tablet Or Pill |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegan, Vegetarian, Adult (18 - 50 Years), Gluten Free, Dairy Free |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for Chewable Digest Orange Flavor by Enzymedica, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Total Carbohydrates | 1 Gram(s) | 1% |
| L-Leucine | 68 mg | -- |
| Amylase | 0 NP | -- |
| Protease | 0 NP | -- |
| Lipase | 0 NP | -- |
| Lactase | 0 NP | -- |
| Cellulase | 0 NP | -- |
| Invertase | 0 NP | -- |
| Glucoamylase | 0 NP | -- |
| Xylanase | 0 NP | -- |
| Pectinase | 0 NP | -- |
| Maltase | 0 NP | -- |
| Beta-Glucanase | 0 NP | -- |
| Phytase | 0 NP | -- |
| Hemicellulase | 0 NP | -- |
| Alpha-Galactosidase | 0 NP | -- |
| Sugar Alcohol | 0.65 Gram(s) | -- |
Other ingredients: Tapioca Dextrose, Citric Acid, Orange Flavor, Natural, Annatto, Rice Concentrate, Tapioca Maltodextrin, Sunflower Lecithin, Palm Oil, Guar Gum
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
General Statements
Enzymedica Supports AHA Autism Hope Alliance Vitamin Angels Proud Supporter Green Mountain Energy
#1 Selling Enzyme Brand
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.
Formulation
Chewable Digest speeds up the digestive process and helps relieve occasional gas, bloating, indigestion and irregularity.
No artificial fillers or sweeteners
Complete Digestive Enzyme Formula Relieves occasional gas, bloating and indigestion Speeds up digestion for more energy
Non GMO Certified by NSF
Vegan Dietary Supplement
Contains No: gluten, milk, casein, soy, egg, artificial colors or flavors.
Suggested/Recommended/Usage/Directions
Recommended Usage: Chew 1-2 tablets at the beginning of each meal.
Formula
Digestive enzymes help the body break down and get nutrients from fats, fiber, proteins and carbohydrates in food. Thera-blend is an exclusive process that combines multiple strains of enzymes that work in wide range pH levels, resulting in superior performance in the body.
Storage
Keep closed in dry place; avoid excessive heat.
Precautions
Do not use if safety seal is broken or missing.
Please keep out of reach of children.
Brand IP Statement(s)
Enzymedica Natural Digestive Health & Wellness
FDA Statement of Identity
Vegan Dietary Supplement
Seals/Symbols
Non GMO Certified by NSF
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
Chewable Digest Orange Flavor by Enzymedica label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in Chewable Digest Orange Flavor by Enzymedica
These are the 15 active ingredients this product is made of. Select any to open its full monograph.
Serving size1 Tablet(s) Dosage formTablet Or Pill Servings per container15 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
L-Leucine
Amylase
Protease
No knowninteractions
Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), tr...
Protease monograph & interactionsLipase
No knowninteractions
Lipase is a digestive enzyme that helps your body break down dietary fats. It is well established as part of prescription pancreatic enzyme therapy fo...
Lipase monograph & interactionsLactase
No knowninteractions
Lactase is a digestive enzyme supplement that helps people who lack enough natural lactase break down lactose, the sugar in milk and dairy. It can red...
Lactase monograph & interactionsCellulase
Invertase
Glucoamylase
Xylanase
Pectinase
Maltase
Beta-Glucanase
Phytase
No knowninteractions
Phytase is an enzyme that breaks down phytic acid (phytate) found in grains, beans, nuts, and seeds, which can free up minerals like iron, zinc, and c...
Phytase monograph & interactionsHemicellulase
Alpha-Galactosidase
Other (inactive) ingredients: Tapioca Dextrose, Citric Acid, Orange Flavor, Natural, Annatto, Rice Concentrate, Tapioca Maltodextrin, Sunflower Lecithin, Palm Oil, Guar Gum. These complete the product’s ingredient list but are not active constituents.
Chewable Digest Orange Flavor by Enzymedica Drug Interactions
We don’t currently list any known drug interactions for the mapped ingredients in Chewable Digest Orange Flavor. This doesn’t guarantee none exist — always confirm with your pharmacist before combining a supplement with your medications.
Brand information
Manufacturer and brand details for Chewable Digest Orange Flavor, from the product label.
Enzymedica
See all Enzymedica products- Name
- Enzymedica, Inc.
- Street Address
- 771 Commerce Drive
- City
- Venice
- State
- FL
- ZipCode
- 34292-1731
- Phone Number
- 1-888-918-1118
- Web Address
- www.enzymedica.com
Chewable Digest Orange Flavor by Enzymedica: Common Questions
Does Chewable Digest Orange Flavor by Enzymedica interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Will this help with lactose intolerance?
Can I take this if I'm pregnant?
Is this safe while breastfeeding?
Can I be allergic to this product?
What are all these enzymes supposed to do?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if Chewable Digest Orange Flavor is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind Chewable Digest Orange Flavor’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Proteolytic Enzymes (proteases)
Proteolytic enzymes are proteins that help break down other proteins, and common examples include bromelain (from pineapple), papain (from papaya), trypsin, chymotrypsin, and pancreatin. Peo...
Read the full Proteolytic Enzymes (proteases) monograph → Herb & supplement monographLipase
Lipase is a digestive enzyme that helps your body break down dietary fats. It is well established as part of prescription pancreatic enzyme therapy for people who cannot make enough of their...
Read the full Lipase monograph → Herb & supplement monographLactase
Lactase is a digestive enzyme supplement that helps people who lack enough natural lactase break down lactose, the sugar in milk and dairy. It can reduce gas, bloating, cramping, and diarrhe...
Read the full Lactase monograph → Herb & supplement monographPhytase
Phytase is an enzyme that breaks down phytic acid (phytate) found in grains, beans, nuts, and seeds, which can free up minerals like iron, zinc, and calcium for absorption. It is widely used...
Read the full Phytase monograph →Sources & How We Checked
Chewable Digest Orange Flavor's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 12 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Proteolytic Enzymes (proteases) 3 references
- Weeks JA, Harper RA, Simon RA, Burdick JD. Assessment of sensitization risk of a laundry pre-spotter containing protease. Cutan Ocul Toxicol. 2011;30(4):272-9. PubMed
- Marquès LI, Lara S, Abós T, Bartolomé B. Occupational rhinitis due to pepsin. J Investig Allergol Clin Immunol. 2006;16(2):136-7. DOI
- Cartier A, Malo JL, Pineau L, Dolovich J. Occupational asthma due to pepsin. J Allergy Clin Immunol. 1984;73(5 Pt 1):574-7. PubMed
See these in context on the Proteolytic Enzymes (proteases) monograph →
Lipase 1 reference
- Casper C, Hascoet JM, Ertl T, et al. Recombinant bile salt-stimulated lipase in preterm infant feeding: A randomized phase 3 study. PLoS One. 2016;11(5):e0156071. PubMed
Lactase 1 reference
- Laukkanen A, Ruoppi P, Remes S, Koistinen T, Mäkinen-Kiljunen S. Lactase-induced occupational protein contact dermatitis and allergic rhinoconjunctivitis. Contact Dermatitis. 2007;57(2):89-93. PubMed
Phytase 7 references
- Lei XG, Weaver JD, Mullaney E, Ullah AH, Azain MJ. Phytase, a new life for an "old" enzyme. Annu Rev Anim Biosci. 2013;1:283-309. PubMed
- Smuts CM, Matsungo TM, Malan L, et al. Effect of small-quantity lipid-based nutrient supplements on growth, psychomotor development, iron status, and morbidity among 6- to 12-mo-old infants in South Africa: a randomized controlled trial. Am J Clin Nutr. 2 PubMed
- van Heemst RC, Sander I, Rooyackers J, et al. Hypersensitivity pneumonitis caused by occupational exposure to phytase. Eur Respir J. 2009;33(6):1507-9. PubMed
- Baur X, Melching-Kollmuss S, Koops F, Strassburger K, Zober A. IgE-mediated allergy to phytase -- a new animal feed additive. Allergy. 2002;57(10):943-5. PubMed
- Doekes G, Kamminga N, Helwegen L, Heederik D. Occupational IgE sensitisation to phytase, a phosphatase derived from Aspergillus niger. Occup Environ Med. 1999;56(7):454-9. PubMed
- Brnic M, Hurrell RF, Songré-Ouattara LT, et al. Effect of phytase on zinc absorption from a millet-based porridge fed to young Burkinabe children. Eur J Clin Nutr. 2017;71(1):137-141. PubMed
- Koshy JC, Sharabi SE, Feldman EM, Hollier LH Jr, Patrinely JR, Soparkar CN. Effect of dietary zinc and phytase supplementation on botulinum toxin treatments. J Drugs Dermatol. 2012;11(4):507-12.
Parts of this content are provided by the Therapeutic Research Center, LLC.
DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
© 2021 Therapeutic Research Center, LLC