Interactions on record — worth a quick check against your medications. Based on 1 of 2 ingredients. Check your meds →
Dietary supplement

Cholesterol Pro Ingredients & Drug Interactions

by NOW

Cholesterol Pro label
See full label image
Tablet Or Pill Category: Botanical With Nutrients
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Cholesterol Pro against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Cholesterol Pro is a dietary supplement by NOW with 2 active ingredients. Its ingredients are commonly taken for high cholesterol, heart and metabolic health, anxiety and stress (aromatherapy).Based on those ingredients, 410 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Bergamonte Full Spectrum Bergamot extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Cholesterol Pro by NOW

Ask about any prescription or over-the-counter medication and we check it for interactions with Cholesterol Pro by NOW — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Cholesterol Pro by NOW

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 16, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 2 of its 2 active ingredients.
  • No proprietary blends here — you can verify the dose of every single component.

Cholesterol Pro contains two active ingredients: Bergamonte Full Spectrum Bergamot extract and Pine Phytosterol powder. Bergamot extract comes from a citrus fruit and contains bergapten, a naturally occurring compound.

Pine phytosterols are plant-derived compounds. The tablet also contains several inactive ingredients — microcrystalline cellulose, croscarmellose sodium, calcium carbonate, magnesium stearate, stearic acid, silicon dioxide, and a vegetarian coating — that help hold the tablet together and make it easier to swallow.

Does it work?

Moderate evidence
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Moderate

Some clinical evidence supports this product's ingredients for its stated purpose, but it isn't conclusive.

Why this rating?
  • The label markets this product for: support healthy cholesterol levels within normal range.
  • We looked for evidence on: Hyperlipidemia, Metabolic syndrome, Nonalcoholic fatty liver disease (NAFLD), dyslipidemia, cardiovascular risk.
  • The strongest evidence on file: Bergamot is rated "Possibly Effective" for Hyperlipidemia (Natural Medicines).
  • Also on file: Bergamot is rated "Insufficient Reliable Evidence To Rate" for Nonalcoholic fatty liver disease (NAFLD), Metabolic syndrome.

Bergamot extract is possibly effective for high cholesterol (hyperlipidemia), based on available evidence. For nonalcoholic fatty liver disease (NAFLD) and autism spectrum disorder, the evidence we hold is insufficient to rate it.

Bergamot is also rated possibly ineffective for mental alertness. We hold no effectiveness data for Pine Phytosterol powder.

The evidence, ingredient by ingredient Bergamot

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

The oral bergamot extract in this product appears generally well tolerated when used short-term, though one person reported heartburn in clinical research. The safety facts we hold advise against taking bergamot during pregnancy and breastfeeding because there isn't enough data to know it's safe in either situation.

You should know that the essential oil of bergamot — different from the extract in this tablet — can be toxic if swallowed and cause sun-related skin damage; avoid direct sun exposure or use high-SPF sunscreen if you use this product, especially if you have fair skin.

Side effects, ingredient by ingredient Bergamot

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Bergamot.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 410 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Cholesterol Pro, check with your doctor or pharmacist if you take photosensitizing drugs (such as certain antibiotics and doxycycline) or antidiabetes medications. Both interactions are Moderate severity, and both could affect how your drugs work.

We have no documented interactions for Pine Phytosterol powder to report.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with some supporting evidence for its stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

If you have high cholesterol and want to explore natural options, Cholesterol Pro's bergamot extract is possibly effective — but it's worth discussing with your doctor first if you take diabetes medications or any drugs that increase sun sensitivity. Pregnant or breastfeeding?

The safety data advises against it. Talk with your pharmacist or doctor before adding this to your routine, particularly if you're on any prescriptions.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 2 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Mar 25, 2021.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Cholesterol Pro, straight from the product label.

Brand NOW
Barcode (UPC) 733739035103
Net contents 120 Tablet(s)
Market status On market
Date entered into DSLD Mar 25, 2021
DSLD ID 245542
Product type Botanical With Nutrients
Supplement form Tablet Or Pill
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Vegan, Vegetarian, Adult (18 - 50 Years), Kosher, Gluten Free, Dairy Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Cholesterol Pro by NOW, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Tablet(s)
Maximum serving Sizes:
2 Tablet(s)
Servings per container
60
UPC/BARCODE
733739035103
IngredientAmount% DV
Bergamonte Full Spectrum Bergamot extract500 mg--
Pine Phytosterol powder800 mg--

Other ingredients: Microcrystalline Cellulose, Croscarmellose Sodium, Calcium Carbonate, Magnesium Stearate, Stearic Acid, Silicon Dioxide, Vegetarian Coating

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested usage: Take 2 tablets twice daily with food for 30 days. Thereafter, as a maintenance dose, take 2 tablets daily with food.

Formula

Cholesterol Pro is a combination of two unique ingredients that have clinically demonstrated their ability to help support serum lipid levels already within the healthy range. Bergamonte is a standardized polyphenolic extract that can help to support cardiovascular health, as well as proper blood sugar management. Plant sterols are also known to support healthy cholesterol levels already within the normal range.

With Bergamonte

Triangle K (Kosher)

FDA Disclaimer Statement

These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure or prevent any disease.

Precautions

Caution: For adults only.

Consult a physician if pregnant/nursing, taking medication, or have a medical condition.

Keep out of reach of children.

Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish or tree nut ingredients. Produced in a GMP facility that process other ingredients containing these allergens.

Formulation

Soy free

Cardiovascular health Supports healthy cholesterol levels already within the normal range

Vegetarian/vegan

Non-GMO

Not manufactured with wheat, gluten, soy, milk, egg, fish, shellfish or tree nut ingredients.

Natural color variation may occur in this product.

FDA Statement of Identity

A Dietary Supplement

Seals/Symbols

Triangle K (Kosher)

GMP Quality Assured

General Statements

Botanicals/herbs Family owned since 1968.

Brand IP Statement(s)

Bergoamonte is a registered trademark of HP Ingredients Corporation.

Storage

Store in a cool, dry place after opening.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Cholesterol Pro by NOW label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Cholesterol Pro label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Cholesterol Pro by NOW

These are the 2 active ingredients this product is made of. Select any to open its full monograph.

Serving size2 Tablet(s) Dosage formTablet Or Pill Servings per container60 Amounts shown are per serving.

Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.

Bergamonte Full Spectrum Bergamot extract

Interacts with
410 drugs
500 mg per serving Form: Bergamot Polyphenolic extract complex, Bruteridine, Flavanones, Melitidine

Bergamot is a Mediterranean citrus fruit, and its standardized extract is most often used to support cholesterol and heart health, with some early but...

Bergamonte Full Spectrum Bergamot extract monograph & interactions

Pine Phytosterol powder

800 mg per serving

Other (inactive) ingredients: Microcrystalline Cellulose, Croscarmellose Sodium, Calcium Carbonate, Magnesium Stearate, Stearic Acid, Silicon Dioxide, Vegetarian Coating. These complete the product’s ingredient list but are not active constituents.

Interaction report

Cholesterol Pro by NOW Drug Interactions

Want to check YOUR meds against Cholesterol Pro?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
410Drugs
410 Moderate

Ingredients driving the most interactions

Bergamonte Full Spectrum Bergamot extract 410

Individual Drug Interactions

The ingredients in Cholesterol Pro interact with 410 drugs. Click any drug to see the details.

1 of the 2 ingredients in Cholesterol Pro interact with drugs. Each result below shows which ingredient is responsible. Bergamonte Full Spectrum Bergamot extract

Each ingredient & the kinds of drugs it affects

For each ingredient in Cholesterol Pro with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Bergamonte Full Spectrum Bergamot extract2 drug types · 410 drugs

Antidiabetes Drugs

Theoretically, taking bergamot with antidiabetes drugs might increase the risk of hypoglycemia.
Animal research suggests that bergamot juice has hypoglycemic effects.

Likelihood Possible Evidence D
Photosensitizing Drugs

Theoretically, topical bergamot essential oil might increase the risk of side effects when used along with photosensitizing drugs.
Bergamot contains bergapten, which has photosensitizing effects.

Likelihood Probable Evidence D
Bergamonte Full Spectrum Bergamot extract full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Cholesterol Pro, from the product label.

NOW

See all NOW products
Name
NOW Foods
Street Address
395 S. Glen Ellyn Rd.
City
Bloomingdale
State
IL
ZipCode
60108
Web Address
nowfoods.com
Pharmacist Counseling Corner

Cholesterol Pro by NOW: Common Questions

Does Cholesterol Pro by NOW interact with any medications?
Yes. Based on its ingredients, Cholesterol Pro has a known interaction with 410 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Cholesterol Pro contains 2 active ingredients, and an interaction can come from any of them. We check every ingredient, combine the results into one list per medication, and show which ingredient and mechanism is responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
The safety data advises against bergamot during pregnancy and breastfeeding because there isn't enough information to know it's safe. Talk with your doctor or pharmacist for personalized advice if you're pregnant, planning to become pregnant, or nursing.
Does bergamot really help with high cholesterol?
Bergamot extract is rated possibly effective for high cholesterol based on available research, but 'possibly effective' means the evidence supports it to some degree — not that it's proven to work in everyone. It's one option to discuss with your doctor as part of your overall cholesterol plan.
What about the Pine Phytosterol powder in this — what does it do?
Pine phytosterols are plant compounds, but we don't hold effectiveness data for this particular ingredient in our facts. If you want to know more about its role in this formula, check with the manufacturer or your pharmacist.
Will this make my skin more sensitive to the sun?
Bergamot contains bergapten, which increases light sensitivity. While the extract in this tablet is generally well tolerated, it's smart to use sunscreen and limit direct sun exposure — especially if you have fair skin — when taking this product.
What side effects should I expect?
The oral extract is generally well tolerated when used short-term. One person in clinical research reported heartburn. If you experience any unusual symptoms, let your pharmacist or doctor know.
Can I take this with my other supplements?
We only have interaction data for prescription and over-the-counter medications, not other supplements. Ask your pharmacist to review everything you're taking together to make sure there are no conflicts.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Cholesterol Pro label
Go deeper

The Full Monographs Behind Cholesterol Pro’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Bergamot

Interacts with 410 drugs

Bergamot is a Mediterranean citrus fruit, and its standardized extract is most often used to support cholesterol and heart health, with some early but promising research. The essential oil i...

Read the full Bergamot monograph →
Sources

Sources & How We Checked

Cholesterol Pro's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 17 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Bergamot 17 references
  1. The Review of Natural Products by Facts and Comparisons. St. Louis, MO: Wolters Kluwer Co., 1999.
  2. Gruenwald J, Brendler T, Jaenicke C. PDR for Herbal Medicines. 1st ed. Montvale, NJ: Medical Economics Company, Inc., 1998.
  3. Naganuma M, Hirose S, Nakayama Y, et al. A study of the phototoxicity of lemon oil. Arch Dermatol Res 1985;278:31-6. . PubMed
  4. Kaddu, S., Kerl, H., and Wolf, P. Accidental bullous phototoxic reactions to bergamot aromatherapy oil. J.Am.Acad.Dermatol. 2001;45(3):458-461. PubMed
  5. Finsterer, J. Earl Grey tea intoxication. Lancet 4-27-2002;359(9316):1484. PubMed
  6. Gruson, L. M. and Chang, M. W. Berloque dermatitis mimicking child abuse. Arch.Pediatr.Adolesc.Med. 2002;156(11):1091-1093. PubMed
  7. Weisenseel, P. and Woitalla, S. [Toxic mustard plaster dematitis and phototoxic dematitis after application of bergamot oil]. MMW.Fortschr.Med. 12-15-2005;147(51-52):53, 55.
  8. Placzek, M., Fromel, W., Eberlein, B., Gilbertz, K. P., and Przybilla, B. Evaluation of phototoxic properties of fragrances. Acta Derm.Venereol. 2007;87(4):312-316. PubMed
  9. Mollace, V., Sacco, I., Janda, E., Malara, C., Ventrice, D., Colica, C., Visalli, V., Muscoli, S., Ragusa, S., Muscoli, C., Rotiroti, D., and Romeo, F. Hypolipemic and hypoglycaemic activity of bergamot polyphenols: from animal models to human studies. F PubMed
  10. Morliere, P., Huppe, G., Averbeck, D., Young, A. R., Santus, R., and Dubertret, L. In vitro photostability and photosensitizing properties of bergamot oil. Effects of a cinnamate sunscreen. J.Photochem.Photobiol.B 1990;7(2-4):199-208. PubMed
  11. Young, A. R., Walker, S. L., Kinley, J. S., Plastow, S. R., Averbeck, D., Morliere, P., and Dubertret, L. Phototumorigenesis studies of 5-methoxypsoralen in bergamot oil: evaluation and modification of risk of human use in an albino mouse skin model. J.P PubMed
  12. Girard, J., Unkovic, J., Delahayes, J., and Lafille, C. [Phototoxicity of Bergamot oil. Comparison between humans and guinea pigs]. Dermatologica 1979;158(4):229-243.
  13. Zaynoun, S. T., Johnson, B. E., and Frain-Bell, W. A study of oil of bergamot and its importance as a phototoxic agent. II. Factors which affect the phototoxic reaction induced by bergamot oil and psoralen derivatives. Contact Dermatitis 1977;3(5):225-23 PubMed
  14. Zacher, K. D. and Ippen, H. [Contact dermatitis caused by bergamot oil]. Derm.Beruf.Umwelt. 1984;32(3):95-97.
  15. Yasui, Y. and Hirone, T. Action spectrum for bergamot-oil phototoxicity measured by sunburn cell counting. J.Dermatol. 1994;21(5):319-322. PubMed
  16. Zaynoun, S. T., Johnson, B. E., and Frain-Bell, W. A study of oil of bergamot and its importance as a phototoxic agent. I. Characterization and quantification of the photoactive component. Br.J.Dermatol. 1977;96(5):475-482. PubMed
  17. Bruno A, Pandolfo G, Crucitti M, Cedro C, Zoccali RA, Muscatello MRA. Bergamot Polyphenolic Fraction Supplementation Improves Cognitive Functioning in Schizophrenia: Data From an 8-Week, Open-Label Pilot Study. J Clin Psychopharmacol 2017;37(4):468-71. PubMed

See these in context on the Bergamot monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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