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Dietary supplement

CinSulin Ingredients & Drug Interactions

by Dr. Rico Perez

Capsule Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

CinSulin is a dietary supplement by Dr. Rico Perez with 1 active ingredient. Its ingredients are commonly taken for blood sugar support, digestive upset, antioxidant support.Based on those ingredients, 442 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are CinSulin. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of CinSulin by Dr. Rico Perez

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

CinSulin is a single-ingredient supplement containing cassia cinnamon, a type of cinnamon used in traditional medicine. It comes in capsule form with inactive ingredients (microcrystalline cellulose, gelatin, magnesium stearate, and silica) that serve as fillers and binders.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Cassia Cinnamon product and its label doesn't state a use — see Cassia Cinnamon's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for cassia cinnamon isn't established in our data for any of the conditions listed — including diabetes, high cholesterol (dyslipidemia), common cold, diarrhea, amenorrhea, and angina. The rating for all of these is insufficient reliable evidence, which means the research so far isn't strong enough to say whether it works.

The evidence, ingredient by ingredient Cassia Cinnamon

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Cassia cinnamon is generally well tolerated in food amounts. At supplement doses, especially high ones taken over weeks or months, there's concern about liver damage from its coumarin content.

In clinical trials, a small number of people reported a rash or, rarely, low blood sugar (hypoglycemia) — one participant had a hypoglycemic seizure, though it's unclear if cinnamon caused it. If you have a known allergy to cinnamon or cinnamic alcohol, avoid this product.

During pregnancy and breastfeeding, food amounts of cinnamon are likely fine, but the safety data advises against high-dose supplement amounts. Talk with your doctor or pharmacist about whether this is right for you.

Side effects, ingredient by ingredient Cassia Cinnamon

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Cassia Cinnamon.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: diabetes medications.
  • For scale: 443 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking CinSulin, double-check any antidiabetes medications (like metformin, insulin, or sulfonylureas) and drugs that can harm the liver. Both interactions are Moderate — your blood sugar or liver function could be affected, and your doctor may need to adjust your prescriptions.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

CinSulin may interest people looking for a single-ingredient cinnamon supplement, but the evidence it works for its listed uses isn't strong yet. Be especially careful if you take diabetes medications or drugs that can affect the liver — this product could amplify their effects.

Check your medications with us before you start, and talk with your pharmacist if you're pregnant, breastfeeding, or have liver concerns.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Jan 23, 2025.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about CinSulin, straight from the product label.

Brand Dr. Rico Perez
Barcode (UPC) 879840000927
Net contents 60 Capsule(s)
Market status On market
Date entered into DSLD Jan 23, 2025
DSLD ID 321015
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for CinSulin by Dr. Rico Perez, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
2 Capsule(s)
Maximum serving Sizes:
2 Capsule(s)
Servings per container
30
UPC/BARCODE
879840000927
IngredientAmount% DV
CinSulin250 mg--

Other ingredients: Microcrystalline Cellulose, Gelatin, Magnesium Stearate, Silica

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Suggested use: Take 2 capsules daily.

Precautions

Note: If you have any health conditions or are taking any medications, consult your health care practitioner before using this product.

Keep out of reach of children.

Storage

Store in a cool, dry place.

Formulation

Manufactured in a cGMP certified facility. Freshness Assured

Seals/Symbols

Made in USA from domestic and foreign materials

FDA Statement of Identity

Dietary Supplement

See for yourself

CinSulin by Dr. Rico Perez label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in CinSulin by Dr. Rico Perez

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size2 Capsule(s) Dosage formCapsule Servings per container30 Amounts shown are per serving.

CinSulin

Interacts with
442 drugs
250 mg per serving Form: Cinnamon bark extract

Cassia cinnamon is the common, inexpensive cinnamon used in cooking, and it is also taken as a supplement, most often for blood sugar support. The evi...

CinSulin monograph & interactions

Other (inactive) ingredients: Microcrystalline Cellulose, Gelatin, Magnesium Stearate, Silica. These complete the product’s ingredient list but are not active constituents.

Interaction report

CinSulin by Dr. Rico Perez Drug Interactions

Want to check YOUR meds against CinSulin?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
442Drugs
442 Moderate

Ingredients driving the most interactions

CinSulin 442

Each ingredient & the kinds of drugs it affects

For each ingredient in CinSulin with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

CinSulin2 drug types · 442 drugs

Antidiabetes Drugs

Theoretically, cassia cinnamon may have additive effects with antidiabetes drugs.
Cassia cinnamon may lower blood glucose levels, and have additive effects in patients treated with antidiabetic agents. Dose adjustments to diabetes medications might be necessary.

Likelihood Possible Evidence B
Hepatotoxic Drugs

Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
There is some concern that ingesting large amounts of cassia cinnamon for an extended duration might cause hepatotoxicity in some people. Cassia cinnamon contains coumarin, which can cause hepatotoxicity in animal models. In humans, very high doses of coumarin from 50-7000 mg/day can result in hepatotoxicity that resolves when coumarin use is discontinued. Lower amounts might also cause liver problems in sensitive people, such as those with liver disease or those taking potentially hepatotoxic agents.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for CinSulin, from the product label.

Dr. Rico Perez

See all Dr. Rico Perez products
Name
Rico-Perez Products, Inc.
Street Address
2295 Coral Way
City
Miami
State
FL
ZipCode
33145
Phone Number
(800) 633-6799
Web Address
www.ricoperez.com
Pharmacist Counseling Corner

CinSulin by Dr. Rico Perez: Common Questions

Does CinSulin by Dr. Rico Perez interact with any medications?
Yes. Based on its ingredients, CinSulin has a known interaction with 442 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
CinSulin contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does cassia cinnamon actually lower blood sugar?
CinSulin's ingredient may lower blood sugar levels in theory, which is why it could have additive effects with diabetes medications. However, we don't have strong evidence yet that it works for diabetes. That's why it's especially important to check with your pharmacist or doctor before taking it if you're on diabetes drugs.
Is cassia cinnamon safe for long-term use?
At food amounts, yes. At supplement doses taken for weeks or months, there's concern about liver damage from coumarin, a compound naturally in cinnamon. Very high coumarin doses (50–7,000 mg per day) have caused liver damage in humans, though it improved once they stopped. Stick to food amounts if you're concerned about liver health.
Can I take this while pregnant or breastfeeding?
Food amounts of cinnamon are likely safe during pregnancy and breastfeeding. High-dose supplement amounts, like those in CinSulin, don't have enough safety data. Talk with your doctor or pharmacist about whether this product is right for you during pregnancy or while breastfeeding.
What are the inactive ingredients, and are there fillers?
CinSulin contains microcrystalline cellulose, gelatin, magnesium stearate, and silica — these are inactive ingredients that serve as fillers and binders in the capsule. If you're sensitive to any of these, let your pharmacist know.
Has anyone had side effects from cassia cinnamon supplements?
In clinical trials, a small number of people reported a rash. One person had low blood sugar (hypoglycemia) with a seizure, though it's not certain cinnamon caused it. People with a known allergy to cinnamon or cinnamic alcohol had skin reactions and should avoid this product.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if CinSulin is safe with your meds?

Our pharmacists answer your medication & supplement questions — free.

Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

CinSulin label
Sources

Sources & How We Checked

CinSulin's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 20 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Cassia Cinnamon 20 references
  1. Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
  2. Khan A, Safdar M, Ali Khan M, et al. Cinnamon improves glucose and lipids of people with type 2 diabetes. Diabetes Care 2003;26:3215-8. PubMed
  3. De Benito V, Alzaga R. Occupational allergic contact dermatitis from cassia (Chinese cinnamon) as a flavouring agent in coffee. Contact Dermatitis 1999;40:165. PubMed
  4. Drake TE, Maibach HI. Allergic contact dermatitis and stomatitis caused by a cinnamic aldehyde-flavored toothpaste. Arch Dermatol 1976;112:202-3.
  5. Press release. Cinnamon capsules to reduce blood sugar are medicinal products! Efficacy has not been scientifically proven - some products contain high levels of coumarin. Federal Institute of Risk Assessment (BfM), Germany, November 11, 2006. Available a
  6. Felter SP, Vassallo JD, Carlton BD, Daston GP. A safety assessment of coumarin taking into account species-specificity of toxicokinetics. Food Chem Toxicol 2006;44:462-75. PubMed
  7. Crawford P. Effectiveness of cinnamon for lowering hemoglobin A1C in patients with type 2 diabetes: a randomized, controlled trial. J Am Board Fam Med 2009;22:507-12. PubMed
  8. Akilen, R., Tsiami, A., Devendra, D., and Robinson, N. Glycated haemoglobin and blood pressure-lowering effect of cinnamon in multi-ethnic Type 2 diabetic patients in the UK: a randomized, placebo-controlled, double-blind clinical trial. Diabet.Med. 2010; PubMed
  9. Lu T, Sheng H Wu J Cheng Y Zhu J Chen Y. Cinnamon extract improves fasting blood glucose and glycosylated hemoglobin level in Chinese patients with type 2 diabetes. Nutr Res. 2012;32(6):408-412. PubMed
  10. Choi, J., Lee, K. T., Ka, H., Jung, W. T., Jung, H. J., and Park, H. J. Constituents of the essential oil of the Cinnamomum cassia stem bark and the biological properties. Arch Pharm Res 2001;24(5):418-423.
  11. Altschuler JA, Casella SJ, MacKenzie TA, Curtis KM. The effect of cinnamon on A1C among adolescents with type 1 diabetes. Diabetes Care 2007;30(4):813-6. PubMed
  12. Stoecker BR, Zhan Z, Luo R, et al. Cinnamon extract lowers blood glucose in hyperglycemic subjects. FASEB J. 2010;22:722.1 (Abstract only). DOI
  13. Admani S, Hill H, Jacob SE. Cinnamon Sugar Scrub Dermatitis: "Natural" Is Not Always Best. Pediatr Dermatol. 2017;34(1):e42-e43. PubMed
  14. Isaac-Renton M, Li MK, Parsons LM. Cinnamon spice and everything not nice: many features of intraoral allergy to cinnamic aldehyde. Dermatitis. 2015;26(3):116-21. PubMed
  15. Vandersall A, Katta R. Eyelid dermatitis as a manifestation of systemic contact dermatitis to cinnamon. Dermatitis. 2015 Jul-Aug;26(4):189. PubMed
  16. Wickenberg J, Lindstedt S, Nilsson J, Hlebowicz J. Cassia cinnamon does not change the insulin sensitivity or the liver enzymes in subjects with impaired glucose tolerance. Nutr J 2014 Sep 24;13:96. PubMed
  17. Brancheau D, Patel B, Zughaib M. Do cinnamon supplements cause acute hepatitis? Am J Case Rep 2015;16:250-4. PubMed
  18. Shekarchizadeh-Esfahani P, Heydarpour F, Izadi F, Jalili C. The effect of cinnamon supplementation on liver enzymes in adults: A systematic review and meta-analysis of randomized controlled trials. Complement Ther Med 2021;58:102699. PubMed
  19. Bernaola J, Valverde-Monge M, Otal-Buesa M, Cullen D, Heras-Mendaza F. Cinnamon allergic contact cheilitis. Contact Dermatitis 2023;88(5):418-419. PubMed
  20. Patel K, Howard M, Tate B. Cheilitis caused by allergic contact dermatitis to cinnamon in chai tea: A case report. Contact Dermatitis 2023;88(3):239-240. PubMed

See these in context on the Cassia Cinnamon monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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