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Dietary supplement

Citrus Limonum Ingredients & Drug Interactions

by UNDA Gemmo

Liquid Category: Botanical
Most serious interaction: Minor
The interaction bottom line Most serious interaction: Minor

Citrus Limonum is a dietary supplement by UNDA Gemmo with 1 active ingredient. Its ingredients are commonly taken for vitamin c source, digestive support, flavoring and aromatherapy.Based on those ingredients, 1 medication has a known interaction with it, the most serious rated minor. The ingredients most likely to interact are Lemon extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Citrus Limonum by UNDA Gemmo

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: lemon extract. Lemon extract is used traditionally for a range of purposes, though the evidence we hold on its effectiveness for specific conditions like hay fever, anxiety, respiratory infections, high blood pressure, and kidney stones shows insufficient reliable data to rate it.

The liquid also contains glycerin, ethanol, and purified water as inactive ingredients.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Lemon product and its label doesn't state a use — see Lemon's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The data we hold does not establish effectiveness for lemon extract for allergic rhinitis (hay fever), anxiety, respiratory tract infections, high blood pressure, or kidney stones. In each case, the evidence is rated insufficient.

If you're considering this product for a specific health goal, talk with your pharmacist or doctor about whether the evidence supports its use for your situation.

The evidence, ingredient by ingredient Lemon

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Lemon as a food or drink is well tolerated in normal amounts. However, concentrated supplements and medicinal doses haven't been as thoroughly studied.

In a clinical trial using fresh lemon juice at higher doses (60 mL twice daily), gastrointestinal side effects were common — about 37% of participants reported some disturbance, with 21% experiencing heartburn and 8% experiencing epigastric pain (discomfort in the upper abdomen). The product facts don't include pregnancy or breastfeeding safety data for lemon extract, so talk with your doctor or pharmacist for personalized guidance if you're pregnant, planning to become pregnant, or breastfeeding.

Side effects, ingredient by ingredient Lemon

Meds to double-check

Minor interactions only
Known Interaction Concern · database check
Minor only

Only Minor-severity interactions are documented for these ingredients.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Lemon.
  • The most serious interaction on file is rated Minor.
  • For scale: 1 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Check your medications if you take itraconazole (Sporanox) — lemon extract can increase its levels and effects. No other medication interactions are documented in our data for the ingredients we could check.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Only minor medication interactions are documented, and safety information is well characterized.

UNDA Gemmo Citrus Limonum is a simple, single-ingredient lemon extract. If you take itraconazole (an antifungal), check with your pharmacist before adding this — it can raise itraconazole levels.

If you're prone to heartburn or stomach upset, be aware that medicinal lemon doses triggered gastrointestinal symptoms in many trial participants.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Dec 26, 2020.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Citrus Limonum, straight from the product label.

Brand UNDA Gemmo
Barcode (UPC) 88319630910
Net contents 4.2 Fluid Ounce(s); 125 mL
Market status On market
Date entered into DSLD Dec 26, 2020
DSLD ID 240994
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other
Intended target group(s) Children 4 or More Years of Age, Adult (18 - 50 Years), Women (not pregnant or lactating)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Citrus Limonum by UNDA Gemmo, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1.25 mL
Maximum serving Sizes:
1.25 mL
Servings per container
100
UPC/BARCODE
88319630910
IngredientAmount% DV
Lemon extract1.25 mL--

Other ingredients: Glycerin, Ethanol, purified Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Recommended dose: Adults and children (over 12 years): Take 50 drops (1.25 ml) three times daily in a small amount of water or as recommended by your healthcare practitioner.

Precautions

Risk Information: If you are pregnant or breastfeeding, do not use, unless directed by your healthcare practitioner. If you are taking any medication or have any health condition, consult your healthcare practitioner prior to use.

Keep our of the reach of children.

Storage

Store in a cool, dry place.

General Statements

Contents may not fill package in order to accommodate required labeling. Please rely on stated quantity.

Seroyal UNDA

Formula

Surculi recentes Young shoot

FDA Statement of Identity

Dietary Supplement

See for yourself

Citrus Limonum by UNDA Gemmo label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Citrus Limonum by UNDA Gemmo

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1.25 mL Dosage formLiquid Servings per container100 Amounts shown are per serving.

Lemon extract

Interacts with
1 drug
1.25 mL per serving

Lemon is a common citrus fruit that is a good source of vitamin C and citric acid, and it is widely used in food, drinks, and home remedies. While it...

Lemon extract monograph & interactions

Other (inactive) ingredients: Glycerin, Ethanol, Purified Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Citrus Limonum by UNDA Gemmo Drug Interactions

Want to check YOUR meds against Citrus Limonum?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
1Drugs
1 Minor

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Citrus Limonum with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Lemon extract1 drug type · 1 drug

Itraconazole (Sporanox)

Theoretically, taking itraconazole capsules or tablets with a beverage containing lemon might increase the levels and clinical effects of itraconazole.
In one case report, dissolving itraconazole tablets in a small amount of specific beverages containing lemon prior to administration increased the level of itraconazole in a lung transplant patient. In this case, the increased bioavailability was desirable and was likely due to improved tablet dissolution in the acidic beverage.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Citrus Limonum, from the product label.

UNDA Gemmo

See all UNDA Gemmo products
Name
Seroyal USA
City
Pittsburg
State
PA
ZipCode
15275
Phone Number
1-888-737-6925
Pharmacist Counseling Corner

Citrus Limonum by UNDA Gemmo: Common Questions

Does Citrus Limonum by UNDA Gemmo interact with any medications?
Yes. Based on its ingredients, Citrus Limonum has a known interaction with 1 medication. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Citrus Limonum contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Does lemon extract actually work for hay fever, anxiety, or high blood pressure?
The evidence we hold rates lemon extract as having insufficient reliable data for each of those conditions. That doesn't mean it doesn't work — it means the studies aren't solid enough to know either way. Talk with your doctor about whether it makes sense to try it for your situation.
Will this give me heartburn?
In a clinical trial, participants taking fresh lemon juice at medicinal doses (60 mL twice daily) reported heartburn in about 21% of cases, compared to 1% in the placebo group. Lemon as a food in normal amounts is fine, but higher medicinal doses carry a real risk of stomach upset.
Is this safe to take while pregnant or breastfeeding?
The safety data on file doesn't address pregnancy or breastfeeding for lemon extract. Because lemon as a food is generally fine but medicinal amounts haven't been well studied, talk with your doctor or pharmacist about what's right for you in those situations.
What's the difference between lemon as a food and this supplement?
Lemon as a food or drink is safe in normal amounts. This product is a concentrated extract taken at medicinal doses, which haven't been studied as thoroughly and carry a higher risk of side effects like heartburn and stomach pain.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Citrus Limonum is safe with your meds?

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Ask a pharmacist

Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Citrus Limonum label
Go deeper

The Full Monographs Behind Citrus Limonum’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Citrus Limonum's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 2 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Lemon 2 references
  1. Ruggenenti P, Caruso MR, Cortinovis M, et al. Fresh lemon juice supplementation for the prevention of recurrent stones in calcium oxalate nephrolithiasis: A pragmatic, prospective, randomised, open, blinded endpoint (PROBE) trial. EClinicalMedicine 2021;4 PubMed
  2. Umemura K, Katada Y, Nakagawa S, et al. Improved absorption of itraconazole tablet by co-administration with lemon beverages in a lung transplant recipient: A case report. J Infect Chemother 2022;28(8):1203-1207. PubMed

See these in context on the Lemon monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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