ClearGuard Ingredients & Drug Interactions
by Nutrilite
What is this page for?
First and foremost: checking ClearGuard against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.
Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy
ClearGuard is a dietary supplement by Nutrilite with 3 active ingredients. Its ingredients are commonly taken for blood sugar support, digestive upset, antioxidant support.Based on those ingredients, 546 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Cinnamon extract, Acerola Concentrate Proprietary Blend. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.
Check Your Meds Against ClearGuard by Nutrilite
Ask about any prescription or over-the-counter medication and we check it for interactions with ClearGuard by Nutrilite — and tell you which ingredient is responsible.
AI summaries are generated from our interaction database for education only — always confirm with your pharmacist. How we use AI
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HelloPharmacist Scorecard of ClearGuard by Nutrilite
Four independent checks of what is known — a summary of the available information, not a grade of the product itself.
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
The stated purpose hasn't been mapped to our evidence data yet.
Why this rating?
- We haven't mapped this product's purpose to our evidence data yet — it'll be graded on the next content refresh.
Most active ingredients list an amount, but at least one is hidden in a blend or missing.
Why this rating?
- The label discloses an exact amount for 2 of its 4 active ingredients.
- “Acerola Concentrate Proprietary Blend” is a proprietary blend — the label gives one combined amount (150 mg) without saying how much of each component you get.
The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.
Why this rating?
- 2 of the 2 matched ingredients can interact with medications — Acerola, Cassia Cinnamon.
- The most serious interaction on file is rated Moderate.
- Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; cancer treatments; diabetes medications.
- For scale: 547 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.
Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.
Why this rating?
- We hold adverse-effect (side-effect) data for 2 of the 2 matched ingredients.
- Pregnancy & breastfeeding safety ratings cover 2 of 2.
- General safety write-ups exist for 2 of 2.
- Remember: this measures how much safety information exists. Thin data is not the same as being safe.
HelloPharmacist summaryPartially disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.
Assessment coverage: 2 of 4 active ingredients matched to our full ingredient reviews (monographs). Based on the product label dated Apr 25, 2018.
This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed
General information
Key facts about ClearGuard, straight from the product label.
| Brand | Nutrilite |
|---|---|
| Barcode (UPC) | 10-2735 |
| Net contents | 180 Tablet(s) |
| Market status | Off market |
| Date entered into DSLD | Apr 25, 2018 |
| DSLD ID | 176296 |
| Product type | Other Combinations |
| Supplement form | Tablet Or Pill |
| Dietary claims / uses | All Other, Structure/Function |
| Intended target group(s) | Vegetarian, Adult (18 - 50 Years), Kosher, Halal |
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.
Supplement Facts
The label details for ClearGuard by Nutrilite, sourced from the NIH Dietary Supplement Label Database.
Supplement Facts
| Ingredient | Amount | % DV |
|---|---|---|
| Corn Starch | 0 NP | -- |
| Cinnamon extract | 150 mg | -- |
| Spanish Needles powder | 150 mg | -- |
| Acerola Concentrate Proprietary Blend | 150 mg | -- |
| Acerola concentrate | 0 NP | -- |
Other ingredients: Maltodextrin, Microcrystalline Cellulose, Stearic Acid, Silicon Dioxide, Sodium Carboxymethylcellulose, Methylcellulose, Glycerin, Carnauba Wax
Tap any ingredient to jump to its full detail below.
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Brand IP Statement(s)
This exclusive, all-natural Nutrilite formula helps support clear nasal passages.
General Statements
No matter what the season or the reason.
Clear nasal passages Quality you can trust since 1934
(a one month supply)
Exclusively from Amway
Formulation
Suitable for vegetarian use.
No artificial flavors, colors, or preservatives added.
FDA Disclaimer Statement
These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Precautions
Children under 12 years of age, nursing mothers, or anyone with a medical condition should consult with a physician before using this product.
Children under 12 years of age, nursing mothers, or anyone with a medical condition should consult with a physician before using this product.
Do not exceed recommended dose.
Pregnant women should avoid taking this product.
Do not take if you have a fever, peptic ulcers, or are allergic to cinnamon.
Storage
Keep bottle tightly closed. Store in a cool, dry place.
FDA Statement of Identity
Dietary Supplement
Suggested/Recommended/Usage/Directions
2 tablets, 3x a day
Suggested use: Take two tablets three times per day, preferably with meals. Continue to take two tablets three times a day as needed for up to 12 weeks at a time.
General
1044285
Seals/Symbols
NSF Contents tested & certified Star K M
Formula
Star K
Halal
Is this label outdated? Report a formula or label change and our pharmacy team will review it.
ClearGuard by Nutrilite label
The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.
Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.
View the full label (PDF)The Ingredients in ClearGuard by Nutrilite
These are the 3 active ingredients this product is made of. Select any to open its full monograph.
Serving size2 Tablet(s) Dosage formTablet Or Pill Servings per container90 Amounts shown are per serving.
Most supplement products combine several ingredients, and a medication can interact with the product through any one of them. Each ingredient below shows whether it has known drug interactions.
Cinnamon extract
Interacts with444 drugs
Cassia cinnamon is the common, inexpensive cinnamon used in cooking, and it is also taken as a supplement, most often for blood sugar support. The evi...
Cinnamon extract monograph & interactionsSpanish Needles powder
Acerola Concentrate Proprietary Blend
Interacts with128 drugs
Acerola is a small tropical fruit prized for its very high natural vitamin C content, and it is mostly used as a food-based source of vitamin C and an...
Acerola Concentrate Proprietary Blend monograph & interactions- › Corn Starch
- › Acerola concentrate
Other (inactive) ingredients: Maltodextrin, Microcrystalline Cellulose, Stearic Acid, Silicon Dioxide, Sodium Carboxymethylcellulose, Methylcellulose, Glycerin, Carnauba Wax. These complete the product’s ingredient list but are not active constituents.
ClearGuard by Nutrilite Drug Interactions
ClearGuard contains 3 ingredients, and 2 of them have known drug interactions. Altogether they interact with 546 medications. Here’s the picture, then you can look up your own drug.
Want to check YOUR meds against ClearGuard?
Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.
Go to the checkerIngredients driving the most interactions
Individual Drug Interactions
The ingredients in ClearGuard interact with 546 drugs. Click any drug to see the details.
2 of the 3 ingredients in ClearGuard interact with drugs. Each result below shows which ingredient is responsible. Cinnamon extract Acerola Concentrate Proprietary Blend
Aspirin, Codeine PhosphateAspirin w/ Codeine
How Aspirin, Codeine Phosphate interacts with ClearGuard — through 1 ingredient. Tap an ingredient for the detail:
Acerola ConcentrateAspirin Minor
Interaction Summary
Theoretically, acerola might reduce the clearance of aspirin; however, its vitamin C content is likely too low to produce clinically significant effects.
Read the full Acerola Concentrate + Aspirin, Codeine Phosphate interactionAspirin, Codeine Phosphate, MethocarbamolRobaxisal C
How Aspirin, Codeine Phosphate, Methocarbamol interacts with ClearGuard — through 1 ingredient. Tap an ingredient for the detail:
Acerola ConcentrateAspirin Minor
Interaction Summary
Theoretically, acerola might reduce the clearance of aspirin; however, its vitamin C content is likely too low to produce clinically significant effects.
Read the full Acerola Concentrate + Aspirin, Codeine Phosphate, Methocarbamol interactionAspirin, Codeine Phosphate, PhenobarbitalPhenaphen
How Aspirin, Codeine Phosphate, Phenobarbital interacts with ClearGuard — through 1 ingredient. Tap an ingredient for the detail:
Acerola ConcentrateAspirin Minor
Interaction Summary
Theoretically, acerola might reduce the clearance of aspirin; however, its vitamin C content is likely too low to produce clinically significant effects.
Read the full Acerola Concentrate + Aspirin, Codeine Phosphate, Phenobarbital interactionAspirin, Diphenhydramine, PhenylpropanolamineAlka Seltzer Plus Night Time Effervescent
How Aspirin, Diphenhydramine, Phenylpropanolamine interacts with ClearGuard — through 1 ingredient. Tap an ingredient for the detail:
Acerola ConcentrateAspirin Minor
Interaction Summary
Theoretically, acerola might reduce the clearance of aspirin; however, its vitamin C content is likely too low to produce clinically significant effects.
Read the full Acerola Concentrate + Aspirin, Diphenhydramine, Phenylpropanolamine interactionAspirin, DipyridamoleAggrenox, Asasantin Retard
How Aspirin, Dipyridamole interacts with ClearGuard — through 1 ingredient. Tap an ingredient for the detail:
Acerola ConcentrateAspirin Minor
Interaction Summary
Theoretically, acerola might reduce the clearance of aspirin; however, its vitamin C content is likely too low to produce clinically significant effects.
Read the full Acerola Concentrate + Aspirin, Dipyridamole interactionAspirin, Ethoheptazine, MeprobamateEquagesic
How Aspirin, Ethoheptazine, Meprobamate interacts with ClearGuard — through 1 ingredient. Tap an ingredient for the detail:
Acerola ConcentrateAspirin Minor
Interaction Summary
Theoretically, acerola might reduce the clearance of aspirin; however, its vitamin C content is likely too low to produce clinically significant effects.
Read the full Acerola Concentrate + Aspirin, Ethoheptazine, Meprobamate interactionAspirin, HydrocodoneAlor 5 500, Lortab ASA
How Aspirin, Hydrocodone interacts with ClearGuard — through 1 ingredient. Tap an ingredient for the detail:
Acerola ConcentrateAspirin Minor
Interaction Summary
Theoretically, acerola might reduce the clearance of aspirin; however, its vitamin C content is likely too low to produce clinically significant effects.
Read the full Acerola Concentrate + Aspirin, Hydrocodone interactionAspirin, MeprobamateMicrainin
How Aspirin, Meprobamate interacts with ClearGuard — through 1 ingredient. Tap an ingredient for the detail:
Acerola ConcentrateAspirin Minor
Interaction Summary
Theoretically, acerola might reduce the clearance of aspirin; however, its vitamin C content is likely too low to produce clinically significant effects.
Read the full Acerola Concentrate + Aspirin, Meprobamate interactionAspirin, MethocarbamolRobaxisal
How Aspirin, Methocarbamol interacts with ClearGuard — through 1 ingredient. Tap an ingredient for the detail:
Acerola ConcentrateAspirin Minor
Interaction Summary
Theoretically, acerola might reduce the clearance of aspirin; however, its vitamin C content is likely too low to produce clinically significant effects.
Read the full Acerola Concentrate + Aspirin, Methocarbamol interactionAspirin, OxycodonePercodan
How Aspirin, Oxycodone interacts with ClearGuard — through 1 ingredient. Tap an ingredient for the detail:
Acerola ConcentrateAspirin Minor
Interaction Summary
Theoretically, acerola might reduce the clearance of aspirin; however, its vitamin C content is likely too low to produce clinically significant effects.
Read the full Acerola Concentrate + Aspirin, Oxycodone interactionAspirin, PentazocineTalwin Compound
How Aspirin, Pentazocine interacts with ClearGuard — through 1 ingredient. Tap an ingredient for the detail:
Acerola ConcentrateAspirin Minor
Interaction Summary
Theoretically, acerola might reduce the clearance of aspirin; however, its vitamin C content is likely too low to produce clinically significant effects.
Read the full Acerola Concentrate + Aspirin, Pentazocine interactionBazedoxifene Acetate, Conjugated EstrogensDuavee
How Bazedoxifene Acetate, Conjugated Estrogens interacts with ClearGuard — through 1 ingredient. Tap an ingredient for the detail:
Acerola ConcentrateEstrogens Minor
Interaction Summary
Theoretically, concomitant use of acerola with estrogens might increase estrogenic effects.
Read the full Acerola Concentrate + Bazedoxifene Acetate, Conjugated Estrogens interactionConjugated EstrogensCenestin, Enjuvia, Premarin, Premarin Vaginal Cream
How Conjugated Estrogens interacts with ClearGuard — through 1 ingredient. Tap an ingredient for the detail:
Acerola ConcentrateEstrogens Minor
Interaction Summary
Theoretically, concomitant use of acerola with estrogens might increase estrogenic effects.
Read the full Acerola Concentrate + Conjugated Estrogens interactionConjugated Estrogens, Medroxyprogesterone AcetatePremplus, Prempro
How Conjugated Estrogens, Medroxyprogesterone Acetate interacts with ClearGuard — through 1 ingredient. Tap an ingredient for the detail:
Acerola ConcentrateEstrogens Minor
Interaction Summary
Theoretically, concomitant use of acerola with estrogens might increase estrogenic effects.
Read the full Acerola Concentrate + Conjugated Estrogens, Medroxyprogesterone Acetate interactionConjugated Estrogens, MeprobamatePMB 200, PMB 400
How Conjugated Estrogens, Meprobamate interacts with ClearGuard — through 1 ingredient. Tap an ingredient for the detail:
Acerola ConcentrateEstrogens Minor
Interaction Summary
Theoretically, concomitant use of acerola with estrogens might increase estrogenic effects.
Read the full Acerola Concentrate + Conjugated Estrogens, Meprobamate interactionCyproterone Acetate, Ethinyl EstradiolDiane-35, Dianette
How Cyproterone Acetate, Ethinyl Estradiol interacts with ClearGuard — through 1 ingredient. Tap an ingredient for the detail:
Acerola ConcentrateEstrogens Minor
Interaction Summary
Theoretically, concomitant use of acerola with estrogens might increase estrogenic effects.
Read the full Acerola Concentrate + Cyproterone Acetate, Ethinyl Estradiol interactionDihydroxyaluminum Sodium CarbonateRolaids
How Dihydroxyaluminum Sodium Carbonate interacts with ClearGuard — through 1 ingredient. Tap an ingredient for the detail:
Acerola ConcentrateAluminum Minor
Interaction Summary
Theoretically, concomitant use of acerola with aluminum salts might increase the amount of aluminum absorbed.
Read the full Acerola Concentrate + Dihydroxyaluminum Sodium Carbonate interactionEsterified EstrogensEstratab, Menest
How Esterified Estrogens interacts with ClearGuard — through 1 ingredient. Tap an ingredient for the detail:
Acerola ConcentrateEstrogens Minor
Interaction Summary
Theoretically, concomitant use of acerola with estrogens might increase estrogenic effects.
Read the full Acerola Concentrate + Esterified Estrogens interactionEstradiolDivigel, Elestrin, Estrace, Estraderm, Estring, Evamist +6 more
How Estradiol interacts with ClearGuard — through 1 ingredient. Tap an ingredient for the detail:
Acerola ConcentrateEstrogens Minor
Interaction Summary
Theoretically, concomitant use of acerola with estrogens might increase estrogenic effects.
Read the full Acerola Concentrate + Estradiol interactionEstradiol, MedroxyprogesteroneDivitren
How Estradiol, Medroxyprogesterone interacts with ClearGuard — through 1 ingredient. Tap an ingredient for the detail:
Acerola ConcentrateEstrogens Minor
Interaction Summary
Theoretically, concomitant use of acerola with estrogens might increase estrogenic effects.
Read the full Acerola Concentrate + Estradiol, Medroxyprogesterone interactionEstradiol, Norethindrone AcetateActivella
How Estradiol, Norethindrone Acetate interacts with ClearGuard — through 1 ingredient. Tap an ingredient for the detail:
Acerola ConcentrateEstrogens Minor
Interaction Summary
Theoretically, concomitant use of acerola with estrogens might increase estrogenic effects.
Read the full Acerola Concentrate + Estradiol, Norethindrone Acetate interactionEstradiol, NorgestimateOrtho-Prefest
How Estradiol, Norgestimate interacts with ClearGuard — through 1 ingredient. Tap an ingredient for the detail:
Acerola ConcentrateEstrogens Minor
Interaction Summary
Theoretically, concomitant use of acerola with estrogens might increase estrogenic effects.
Read the full Acerola Concentrate + Estradiol, Norgestimate interactionEstradiol, ProgesteroneBijuvanda
How Estradiol, Progesterone interacts with ClearGuard — through 1 ingredient. Tap an ingredient for the detail:
Acerola ConcentrateEstrogens Minor
Interaction Summary
Theoretically, concomitant use of acerola with estrogens might increase estrogenic effects.
Read the full Acerola Concentrate + Estradiol, Progesterone interactionEstrogenEstrogen
How Estrogen interacts with ClearGuard — through 1 ingredient. Tap an ingredient for the detail:
Acerola ConcentrateEstrogens Minor
Interaction Summary
Theoretically, concomitant use of acerola with estrogens might increase estrogenic effects.
Read the full Acerola Concentrate + Estrogen interactionEstroneOrtho-Est
How Estrone interacts with ClearGuard — through 1 ingredient. Tap an ingredient for the detail:
Acerola ConcentrateEstrogens Minor
Interaction Summary
Theoretically, concomitant use of acerola with estrogens might increase estrogenic effects.
Read the full Acerola Concentrate + Estrone interactionEstropipateOgen, Ortho EST
How Estropipate interacts with ClearGuard — through 1 ingredient. Tap an ingredient for the detail:
Acerola ConcentrateEstrogens Minor
Interaction Summary
Theoretically, concomitant use of acerola with estrogens might increase estrogenic effects.
Read the full Acerola Concentrate + Estropipate interactionEthiny Estradiol, LevonorgestrelLogynon, Microgynon 30 ED
How Ethiny Estradiol, Levonorgestrel interacts with ClearGuard — through 1 ingredient. Tap an ingredient for the detail:
Acerola ConcentrateEstrogens Minor
Interaction Summary
Theoretically, concomitant use of acerola with estrogens might increase estrogenic effects.
Read the full Acerola Concentrate + Ethiny Estradiol, Levonorgestrel interactionEthinyl EstradiolEstinyl
How Ethinyl Estradiol interacts with ClearGuard — through 1 ingredient. Tap an ingredient for the detail:
Acerola ConcentrateEstrogens Minor
Interaction Summary
Theoretically, concomitant use of acerola with estrogens might increase estrogenic effects.
Read the full Acerola Concentrate + Ethinyl Estradiol interactionEtonogestrel, Ethinyl EstradiolNuvaRing
How Etonogestrel, Ethinyl Estradiol interacts with ClearGuard — through 1 ingredient. Tap an ingredient for the detail:
Acerola ConcentrateEstrogens Minor
Interaction Summary
Theoretically, concomitant use of acerola with estrogens might increase estrogenic effects.
Read the full Acerola Concentrate + Etonogestrel, Ethinyl Estradiol interactionFish Oil TriglyceridesOmegaven
How Fish Oil Triglycerides interacts with ClearGuard — through 1 ingredient. Tap an ingredient for the detail:
Acerola ConcentrateAluminum Minor
Interaction Summary
Theoretically, concomitant use of acerola with aluminum salts might increase the amount of aluminum absorbed.
Read the full Acerola Concentrate + Fish Oil Triglycerides interactionEach ingredient & the kinds of drugs it affects
For each ingredient in ClearGuard with known interactions, here are the types of medications they can affect. Open any type for the detail — or search your exact drug in the checker above.
Cinnamon extract
Antidiabetes Drugs
Theoretically, cassia cinnamon may have additive effects with antidiabetes drugs.
Cassia cinnamon may lower blood glucose levels, and have additive effects in patients treated with antidiabetic agents. Dose adjustments to diabetes medications might be necessary.
Hepatotoxic Drugs
Theoretically, large doses of cassia cinnamon might cause additive effects when used with hepatotoxic drugs.
There is some concern that ingesting large amounts of cassia cinnamon for an extended duration might cause hepatotoxicity in some people. Cassia cinnamon contains coumarin, which can cause hepatotoxicity in animal models. In humans, very high doses of coumarin from 50-7000 mg/day can result in hepatotoxicity that resolves when coumarin use is discontinued. Lower amounts might also cause liver problems in sensitive people, such as those with liver disease or those taking potentially hepatotoxic agents.
Acerola Concentrate Proprietary Blend
Alkylating Agents
Theoretically, the antioxidant effects of acerola might reduce the effectiveness of alkylating agents.
Acerola contains vitamin C, an antioxidant. There is concern that antioxidants might reduce the activity of chemotherapy drugs that generate free radicals, such as alkylating agents. In contrast, other researchers theorize that antioxidants might make alkylating chemotherapy more effective by reducing oxidative stress that could interfere with apoptosis (cell death) of cancer cells. More evidence is needed to determine what effect, if any, antioxidants such as vitamin C have on chemotherapy.
Antitumor Antibiotics
Theoretically, the antioxidant effects of acerola might reduce the effectiveness of antitumor antibiotics.
Acerola contains vitamin C, an antioxidant. There is concern that antioxidants might reduce the activity of chemotherapy drugs that generate free radicals, such as antitumor antibiotics. In contrast, other researchers theorize that antioxidants might make antitumor antibiotic chemotherapy more effective by reducing oxidative stress that could interfere with apoptosis (cell death) of cancer cells. More evidence is needed to determine what effects, if any, antioxidants such as vitamin C have on antitumor antibiotic chemotherapy.
Aluminum
Theoretically, concomitant use of acerola with aluminum salts might increase the amount of aluminum absorbed.
Acerola contains vitamin C. It is thought that vitamin C chelates aluminum, keeping it in solution and available for absorption. In people with normal renal function, urinary excretion of aluminum likely increases, making aluminum retention and toxicity unlikely. However, patients with renal failure who take aluminum-containing compounds, such as phosphate binders, should avoid acerola in doses that provide more vitamin C than the recommended dietary allowances.
Aspirin
Theoretically, acerola might reduce the clearance of aspirin; however, its vitamin C content is likely too low to produce clinically significant effects.
Acerola contains vitamin C. It has been suggested that acidification of the urine by vitamin C can decrease the urinary excretion of salicylates, increasing plasma salicylate levels. However, short-term use of up to 6 grams daily of vitamin C does not seem to affect urinary pH or salicylate excretion. The vitamin C content of acerola is typically about 2000 mg per 100 grams. Thus, a clinically significant interaction between acerola and aspirin is unlikely.
Estrogens
Theoretically, concomitant use of acerola with estrogens might increase estrogenic effects.
Acerola contains vitamin C. Increases in plasma estrogen levels of up to 55% have occurred under some circumstances when vitamin C is taken concurrently with oral contraceptives or hormone replacement therapy, including topical products. It is suggested that vitamin C prevents oxidation of estrogen in the tissues, regenerates oxidized estrogen, and reduces sulfate conjugation of estrogen in the gut wall. When tissue levels of vitamin C are high, these processes are already maximized and supplemental vitamin C does not have any effect on estrogen levels. However, increases in plasma estrogen levels may occur when women who are deficient in vitamin C take supplements.
Warfarin (Coumadin)
Theoretically, acerola might reduce the effectiveness of warfarin; however, its vitamin C content is likely too low to produce clinically significant effects.
Acerola contains vitamin C. High doses of vitamin C may reduce the response to warfarin, possibly by causing diarrhea and reducing warfarin absorption. This occurred in two people who took up to 16 grams daily of vitamin C, and resulted in decreased prothrombin time. Lower doses of 5-10 grams daily of vitamin C can also reduce warfarin absorption, but this does not seem to be clinically significant. The vitamin C content of acerola is typically about 2000 mg per 100 grams. Thus, a clinically significant interaction between acerola and warfarin is unlikely.
Brand information
Manufacturer and brand details for ClearGuard, from the product label.
Nutrilite
See all Nutrilite products- Name
- Amway Corp.
- City
- Ada
- State
- MI
- ZipCode
- 49355
- Phone Number
- 1-800-253-6500
- Web Address
- Amway.com/Nutrilite
ClearGuard by Nutrilite: Common Questions
Does ClearGuard by Nutrilite interact with any medications?
How can one product interact with so many drugs?
Where does this information come from?
Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy
Not sure if ClearGuard is safe with your meds?
Our pharmacists answer your medication & supplement questions — free.
Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.
The Full Monographs Behind ClearGuard’s Ingredients
Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.
Cassia Cinnamon
Interacts with 444 drugsCassia cinnamon is the common, inexpensive cinnamon used in cooking, and it is also taken as a supplement, most often for blood sugar support. The evidence for its health benefits is mixed a...
Read the full Cassia Cinnamon monograph → Herb & supplement monographAcerola
Interacts with 128 drugsAcerola is a small tropical fruit prized for its very high natural vitamin C content, and it is mostly used as a food-based source of vitamin C and antioxidants. While vitamin C itself has w...
Read the full Acerola monograph →Sources & How We Checked
ClearGuard's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.
- NIH Dietary Supplement Label Database (DSLD) — The official product label on file for this supplement.
- Natural Medicines (Therapeutic Research Center) — Evidence-graded clinical reference behind the ingredient interaction data.
Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.
The 40 references behind this product’s interaction data
Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.
Cassia Cinnamon 20 references
- Electronic Code of Federal Regulations. Title 21. Part 182 -- Substances Generally Recognized As Safe. Available at: https://www.accessdata.fda.gov/scripts/cdrh/cfdocs/cfcfr/CFRSearch.cfm?CFRPart=182
- Khan A, Safdar M, Ali Khan M, et al. Cinnamon improves glucose and lipids of people with type 2 diabetes. Diabetes Care 2003;26:3215-8. PubMed
- De Benito V, Alzaga R. Occupational allergic contact dermatitis from cassia (Chinese cinnamon) as a flavouring agent in coffee. Contact Dermatitis 1999;40:165. PubMed
- Drake TE, Maibach HI. Allergic contact dermatitis and stomatitis caused by a cinnamic aldehyde-flavored toothpaste. Arch Dermatol 1976;112:202-3.
- Press release. Cinnamon capsules to reduce blood sugar are medicinal products! Efficacy has not been scientifically proven - some products contain high levels of coumarin. Federal Institute of Risk Assessment (BfM), Germany, November 11, 2006. Available a
- Felter SP, Vassallo JD, Carlton BD, Daston GP. A safety assessment of coumarin taking into account species-specificity of toxicokinetics. Food Chem Toxicol 2006;44:462-75. PubMed
- Crawford P. Effectiveness of cinnamon for lowering hemoglobin A1C in patients with type 2 diabetes: a randomized, controlled trial. J Am Board Fam Med 2009;22:507-12. PubMed
- Akilen, R., Tsiami, A., Devendra, D., and Robinson, N. Glycated haemoglobin and blood pressure-lowering effect of cinnamon in multi-ethnic Type 2 diabetic patients in the UK: a randomized, placebo-controlled, double-blind clinical trial. Diabet.Med. 2010; PubMed
- Lu T, Sheng H Wu J Cheng Y Zhu J Chen Y. Cinnamon extract improves fasting blood glucose and glycosylated hemoglobin level in Chinese patients with type 2 diabetes. Nutr Res. 2012;32(6):408-412. PubMed
- Choi, J., Lee, K. T., Ka, H., Jung, W. T., Jung, H. J., and Park, H. J. Constituents of the essential oil of the Cinnamomum cassia stem bark and the biological properties. Arch Pharm Res 2001;24(5):418-423.
- Altschuler JA, Casella SJ, MacKenzie TA, Curtis KM. The effect of cinnamon on A1C among adolescents with type 1 diabetes. Diabetes Care 2007;30(4):813-6. PubMed
- Stoecker BR, Zhan Z, Luo R, et al. Cinnamon extract lowers blood glucose in hyperglycemic subjects. FASEB J. 2010;22:722.1 (Abstract only). DOI
- Admani S, Hill H, Jacob SE. Cinnamon Sugar Scrub Dermatitis: "Natural" Is Not Always Best. Pediatr Dermatol. 2017;34(1):e42-e43. PubMed
- Isaac-Renton M, Li MK, Parsons LM. Cinnamon spice and everything not nice: many features of intraoral allergy to cinnamic aldehyde. Dermatitis. 2015;26(3):116-21. PubMed
- Vandersall A, Katta R. Eyelid dermatitis as a manifestation of systemic contact dermatitis to cinnamon. Dermatitis. 2015 Jul-Aug;26(4):189. PubMed
- Wickenberg J, Lindstedt S, Nilsson J, Hlebowicz J. Cassia cinnamon does not change the insulin sensitivity or the liver enzymes in subjects with impaired glucose tolerance. Nutr J 2014 Sep 24;13:96. PubMed
- Brancheau D, Patel B, Zughaib M. Do cinnamon supplements cause acute hepatitis? Am J Case Rep 2015;16:250-4. PubMed
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DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.
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