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Dietary supplement

Codonopsis Alcohol Free Ingredients & Drug Interactions

by Herbal Terra

Liquid Category: Botanical
Most serious interaction: Moderate
The interaction bottom line Most serious interaction: Moderate

Codonopsis Alcohol Free is a dietary supplement by Herbal Terra with 1 active ingredient. Its ingredients are commonly taken for fatigue and low energy, digestive support and poor appetite, immune support.Based on those ingredients, 211 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Codonopsis Root Extract. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

HelloPharmacist Scorecard of Codonopsis Alcohol Free by Herbal Terra

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

This product contains one active ingredient: Codonopsis Root Extract. It's a traditional herbal remedy used in folk medicine for various purposes.

The extract is mixed with glycerin and water to create the liquid form.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Codonopsis product and its label doesn't state a use — see Codonopsis's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence isn't established in our data. Codonopsis has been studied for asthma, cancer, respiratory tract infections, indigestion, and high cholesterol, but we hold insufficient reliable evidence to rate it for any of these uses.

If you're considering it for a specific health reason, talk with your pharmacist or doctor about what the current evidence shows.

The evidence, ingredient by ingredient Codonopsis

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Codonopsis is generally well tolerated in traditional food-like amounts, but high-quality safety data are limited. Very large doses (30–60 grams) may cause chest pain, irregular heartbeat, throat pain, or loss of voice.

Allergic reactions including anaphylaxis and hives (urticaria) are possible — one case report documents an 18-year-old who developed anaphylaxis after consuming 20 grams of codonopsis root and again when re-challenged. The safety data advises against use during pregnancy.

Safety while breastfeeding is unknown, so avoid it unless your doctor advises otherwise.

Side effects, ingredient by ingredient Codonopsis

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Codonopsis.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 211 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking this product, check your medications with the tool on this page if you use blood thinners (anticoagulants or antiplatelet drugs like warfarin or aspirin), abiraterone for prostate cancer, or any diabetes medication. These are the medication types we have documented interactions for.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Codonopsis is a single-ingredient herbal extract with limited high-quality safety and effectiveness data. If you take blood thinners, abiraterone, or diabetes medications, check with your pharmacist first — this product may affect how they work.

Even outside those categories, let your pharmacist know before you start.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Nov 22, 2024.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Codonopsis Alcohol Free, straight from the product label.

Brand Herbal Terra
Barcode (UPC) 7386004988968
Net contents 2 Fluid Ounce(s); 60 mL
Market status On market
Date entered into DSLD Nov 22, 2024
DSLD ID 324102
Product type Botanical
Supplement form Liquid
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years), Gluten Free, Sugar Free
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Codonopsis Alcohol Free by Herbal Terra, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 mL
Maximum serving Sizes:
1 mL
Servings per container
60
UPC/BARCODE
7386004988968
IngredientAmount% DV
Codonopsis Root Extract1156 mg--

Other ingredients: Glycerin, Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
Suggested/Recommended/Usage/Directions

Shake well before use. Adults take up to 30 drops (1 mL, one full squeeze of the dropper bulb) in 3-4 fl. oz. of juice or water up to 4 times a day.

Precautions

We recommend to seek expert medical advice before taking. May have contraindications and cause adverse reaction.

Consult a physician before giving to children under 18, before using during pregnancy, if nursing, or if you are on any medications.

Consult a physician before giving to children under 18, before using during pregnancy, if nursing, or if you are on any medications. Keep out of the reach of children!

Do not use if you are allergic to any ingredients.

Storage

Store in a cool, dry, dark place.

FDA Disclaimer Statement

This product has not been evaluated by the FDA and is not intended to diagnose, treat, cure or prevent any disease.

Formulation

cGMP Made in compliance with cGMP 21 CFR 111 in an FDA registered and inspected facility.

Sugar free

Expertly extracted 100% natural Premium product

No alcohol (ethyl), artificial ingredients, color additives, fillers or binders.

Natural Gluten free

Formula

Codonopsis pilosula

FDA Statement of Identity

Herbal Supplement

Seals/Symbols

Made in USA

See for yourself

Codonopsis Alcohol Free by Herbal Terra label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

What’s inside

The Ingredients in Codonopsis Alcohol Free by Herbal Terra

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 mL Dosage formLiquid Servings per container60 Amounts shown are per serving.

Codonopsis Root Extract

Interacts with
211 drugs
1156 mg per serving Form: Codonopsis pilosula Root Extract

Codonopsis (often called 'dang shen') is a root long used in Traditional Chinese Medicine as a gentle energy and digestive tonic, frequently as a mild...

Codonopsis Root Extract monograph & interactions

Other (inactive) ingredients: Glycerin, Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Codonopsis Alcohol Free by Herbal Terra Drug Interactions

Want to check YOUR meds against Codonopsis Alcohol Free?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

Go to the checker
211Drugs
211 Moderate

Ingredients driving the most interactions

Each ingredient & the kinds of drugs it affects

For each ingredient in Codonopsis Alcohol Free with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Codonopsis Root Extract3 drug types · 211 drugs

Abiraterone (Zytiga)

Theoretically, taking codonopsis root with abiraterone might reduce the levels and therapeutic effects of abiraterone.
Animal research in rats shows that intragastric administration of codonopsis root along with abiraterone every 2 days for 2 weeks seems to increase the clearance of abiraterone and reduce the overall exposure and time to maximum concentration. This interaction has not been reported in humans.

Likelihood Possible Evidence D
Anticoagulant/Antiplatelet Drugs

Theoretically, codonopsis liquor might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
A small clinical study in adults with coronary heart disease shows that consuming Codonopsis pilosula liquor for 4 weeks inhibits platelet aggregation but does not affect tissue-type plasminogen activator (t-PA) or plasminogen activator inhibitor (PAI).

Likelihood Possible Evidence B
Antidiabetes Drugs

Theoretically, codonopsis might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Laboratory and animal research suggest that codonopsis has antidiabetic effects.

Likelihood Possible Evidence D
The maker

Brand information

Manufacturer and brand details for Codonopsis Alcohol Free, from the product label.

Herbal Terra

See all Herbal Terra products
Name
Herbal Terra LLC
Phone Number
+18083857868
Web Address
herbalterra.com
Pharmacist Counseling Corner

Codonopsis Alcohol Free by Herbal Terra: Common Questions

Does Codonopsis Alcohol Free by Herbal Terra interact with any medications?
Yes. Based on its ingredients, Codonopsis Alcohol Free has a known interaction with 211 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Codonopsis Alcohol Free contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
Can I take this if I'm pregnant or breastfeeding?
Not during pregnancy — there isn't enough reliable safety information, so it's best avoided. If you're breastfeeding, safety is unknown, so don't take it unless your doctor advises otherwise. Talk with your doctor or pharmacist for personalized advice.
What are the side effects?
At normal doses, codonopsis is generally well tolerated. At very large doses (30–60 grams), it may cause chest pain, irregular heartbeat, throat pain, or loss of voice. Allergic reactions including anaphylaxis and hives are possible, though rare. If you develop any unusual symptoms, stop and contact your pharmacist or doctor.
Does codonopsis really work for asthma, colds, or digestive issues?
We don't have sufficient reliable evidence to say whether it works for those uses. It's been studied, but the data isn't strong enough to rate it. If you're using it for a specific condition, your pharmacist can discuss what evidence exists.
What is codonopsis root extract?
It's a concentrated extract from the codonopsis root, a plant used traditionally in herbal medicine. This product is alcohol-free and mixed with glycerin and water.
Is this product a safe dose if I take diabetes or blood thinner medication?
That's a conversation for your pharmacist or doctor — the interactions are documented, so they need to assess your specific situation and medications. Don't start this product without checking first.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

Not sure if Codonopsis Alcohol Free is safe with your meds?

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Codonopsis Alcohol Free label
Go deeper

The Full Monographs Behind Codonopsis Alcohol Free’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Sources

Sources & How We Checked

Codonopsis Alcohol Free's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 5 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Codonopsis 5 references
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Xu, X., Wang, S. R., and Lin, Q. [Clinical and experimental study on codonopsis pilosula oral liquor in treating coronary heart disease with blood stasis]. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. 1995;15(7):398-400.
  3. Hur GY, Choi GS, Park HJ, Ye YM, Park HS. Anaphylactic shock induced by Codonopsis lanceolata, traditional Chinese medicine in a patient with allergic rhinitis. Allergy. 2008;63(10):1406-7.
  4. Zhang ZB, Ip SP, Cho WCS, et al. Herb-drug interactions between androgenic Chinese herbal medicines and androgen receptor antagonist on tumor growth: Studies on two xenograft prostate cancer animal models. Phytother Res. 2021.
  5. Jia W, Bi Q, Jiang S, et al. Hypoglycemic activity of Codonopsis pilosula (Franch.) Nannf. in vitro and in vivo and its chemical composition identification by UPLC-Triple-TOF-MS/MS. Food Funct 2022;13(5):2456-2464.

See these in context on the Codonopsis monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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