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Dietary supplement

Codonopsis Root 450 mg Ingredients & Drug Interactions

by TerraVita Premium Collection

Codonopsis Root 450 mg label
See full label image
Capsule Category: Botanical
Most serious interaction: Moderate
Clinical methodology reviewed by · Updated Sep 16, 2026 · Label data from the NIH DSLD
What is this page for?

First and foremost: checking Codonopsis Root 450 mg against your medications. The heart of this page is the interaction checker and the full interaction report — how this product’s ingredients may interact with prescription and over-the-counter medicines you may be taking.

Around that, we add a pharmacist’s high-level view of the product as a whole — what’s inside, the evidence for its stated use, how transparent the label is, and what safety data exists — so you can see the full picture in one place. It’s educational information from our licensed clinical databases and the clinical staff at HelloPharmacist — not medical advice — and we don’t sell or endorse products. Our editorial policy

The interaction bottom line Most serious interaction: Moderate

Codonopsis Root 450 mg is a dietary supplement by TerraVita Premium Collection with 1 active ingredient. Its ingredients are commonly taken for fatigue and low energy, digestive support and poor appetite, immune support.Based on those ingredients, 211 medications have a known interaction with it, the most serious rated moderate. The ingredients most likely to interact are Codonopsis. Use the checker below to test your specific medication, or read the full HelloPharmacist Interaction Report.

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Check Your Meds Against Codonopsis Root 450 mg by TerraVita Premium Collection

Ask about any prescription or over-the-counter medication and we check it for interactions with Codonopsis Root 450 mg by TerraVita Premium Collection — and tell you which ingredient is responsible.

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HelloPharmacist Scorecard of Codonopsis Root 450 mg by TerraVita Premium Collection

Our pharmacy team’s full take, with four database checks built into the cards below — a summary of what is known, not a grade of the product itself.

From our pharmacy team — supplement deep dive

Generated from HelloPharmacist’s pharmacist-curated databases and editorial rules · Last generated Jul 16, 2026

What’s inside

Full disclosure
Ingredient Transparency · database check
Full

Every active ingredient lists its own amount on the label.

Why this rating?
  • The label discloses an exact amount for 1 of its 1 active ingredient.
  • No proprietary blends here — you can verify the dose of every single component.

Codonopsis Root 450 mg by TerraVita Premium Collection contains one active ingredient: codonopsis root at 450 milligrams per capsule. The capsule itself is made from gelatin and water.

Does it work?

Couldn't assess
Evidence for Intended Use · database check
By FDA rules, dietary supplements can’t claim to treat, cure, or prevent disease — so labels speak in careful marketing language. We discern each product’s intended use from its name, label claims, and label statements, then grade the clinical evidence for that use. How these ratings are computed
Not assessable

This is a single-ingredient Codonopsis product and its label doesn't state a use — see Codonopsis's own graded uses on its monograph.

Why this rating?
  • We looked at the product name, claims, and label statements and couldn't find a stated purpose to grade.

The evidence for codonopsis isn't established in the data we hold. We have insufficient reliable evidence to rate it for asthma, cancer, respiratory tract infections, indigestion (dyspepsia), or high cholesterol (hyperlipidemia).

If you're considering this supplement for one of these uses, talk it over with your doctor or pharmacist about what the current evidence actually supports.

The evidence, ingredient by ingredient Codonopsis

How safe is it?

Well-documented data
Safety Information · database check
Well characterized

Adverse-effect, pregnancy, and general safety data are on file for most of these ingredients.

Why this rating?
  • We hold adverse-effect (side-effect) data for 1 of the 1 matched ingredient.
  • Pregnancy & breastfeeding safety ratings cover 1 of 1.
  • General safety write-ups exist for 1 of 1.
  • Remember: this measures how much safety information exists. Thin data is not the same as being safe.

Codonopsis is generally well tolerated in traditional food-like amounts, but high-quality safety data are limited. At very large doses — 30 to 60 grams — it may cause chest pain, irregular heartbeat, throat pain, or loss of voice.

Allergic reactions are possible, including severe ones: one case report describes an 18-year-old who developed anaphylaxis (a life-threatening reaction) after ingesting codonopsis root, and the reaction recurred when he was re-challenged with 20 grams. The safety data advises against use during pregnancy.

Safety while breastfeeding is unknown, so avoid it unless your doctor advises otherwise. If you're pregnant, planning pregnancy, or breastfeeding, talk with your doctor or pharmacist before taking this product.

Side effects, ingredient by ingredient Codonopsis

Meds to double-check

Moderate interaction found
Known Interaction Concern · database check
Moderate identified

The most serious documented interaction for these ingredients is Moderate. Check your medications for a personalized result.

Why this rating?
  • 1 of the 1 matched ingredient can interact with medications — Codonopsis.
  • The most serious interaction on file is rated Moderate.
  • Some involve high-stakes drug classes: anticoagulant / antiplatelet drugs; diabetes medications.
  • For scale: 211 individual medications appear in the full list. A big number alone doesn't make a product dangerous — what matters is whether YOUR medication is on it, so run yours through the interaction checker on this page.

Before taking Codonopsis Root 450 mg, check with your doctor or pharmacist if you take blood thinners or antiplatelet drugs (like warfarin, aspirin, or clopidogrel) — codonopsis may increase bleeding risk. Also double-check if you take diabetes medications, since codonopsis may lower blood sugar.

If you take abiraterone (Zytiga) for prostate cancer, codonopsis may reduce how well it works.

Check your own medication Run your meds through the checker above

The bottom line

Scorecard at a glanceFully disclosed formula with no assessable stated purpose. Moderate medication interactions have been identified, and safety information is well characterized.

Codonopsis is a single-ingredient supplement that's generally well tolerated at typical doses, but the evidence for what it actually does isn't established in our data. If you take blood thinners, diabetes medications, or abiraterone for prostate cancer, this isn't a product to start without checking with your doctor or pharmacist first.

Pregnant and breastfeeding people should avoid it unless their healthcare provider specifically advises otherwise.

Educational only — not medical advice; always confirm with your pharmacist. Our editorial policy · How we use AI

Assessment coverage: 1 of 1 active ingredient matched to our full ingredient reviews (monographs). Based on the product label dated Apr 21, 2023.

This Scorecard evaluates available label information, ingredient evidence, and known medication-safety considerations. It does not independently verify product identity, purity, potency, contamination, or manufacturing quality. How these ratings are computed

At a glance

General information

Key facts about Codonopsis Root 450 mg, straight from the product label.

Brand TerraVita Premium Collection
Barcode (UPC) 064435165918
Net contents 100 Capsule(s)
Market status On market
Date entered into DSLD Apr 21, 2023
DSLD ID 287580
Product type Botanical
Supplement form Capsule
Dietary claims / uses All Other, Structure/Function
Intended target group(s) Adult (18 - 50 Years)
From the label
Everything in this section is reproduced from the manufacturer’s own product label — it’s the label speaking, not HelloPharmacist. We show it so you can see exactly what the maker states; we don’t verify or endorse those statements.

Supplement Facts

The label details for Codonopsis Root 450 mg by TerraVita Premium Collection, sourced from the NIH Dietary Supplement Label Database.

Supplement Facts

Daily Value (DV) Target Group(s):
Adults and children 4 or more years of age
Minimum serving Sizes:
1 Capsule(s)
Maximum serving Sizes:
1 Capsule(s)
Servings per container
100
UPC/BARCODE
064435165918
IngredientAmount% DV
Codonopsis450 mg--

Other ingredients: Gelatin, Water

Tap any ingredient to jump to its full detail below.

Label statements
These statements are the manufacturer’s wording, reproduced from the product label — the label is saying it, not HelloPharmacist. We don’t verify or endorse them.
FDA Statement of Identity

A Dietary Supplement

Brand IP Statement(s)

Copyright 2006 TerraVita - Distributed by ZooScape LLC, All Rights Reserved.

Suggested/Recommended/Usage/Directions

Directions Take 1 capsule, 3 times daily, with meals.

General Statements

TerraVita is an exclusive line of premium natural products that use the finest, purest and most potent ingredients in the world. TerraVita's hallmarks are the highest possible standards of purity, potency, stability and freshness. All products are prepared with the greatest quality control, from raw materials through the entire manufacturing process, right up to the moment your product is sealed for freshness and shipped to you.

Please recycle!

FDA Disclaimer Statement

Statements not evaluated by FDA. Product not intended to diagnose, treat, cure, or prevent any disease.

Is this label outdated? Report a formula or label change and our pharmacy team will review it.

See for yourself

Codonopsis Root 450 mg by TerraVita Premium Collection label

The label scan from the NIH Dietary Supplement Label Database. Tap to enlarge.

Codonopsis Root 450 mg label

Label images are published by the NIH Dietary Supplement Label Database for the version of this product on file. Always read your actual product label.

View the full label (PDF)
What’s inside

The Ingredients in Codonopsis Root 450 mg by TerraVita Premium Collection

This is the 1 active ingredient this product is made of. Select it to open its full monograph.

Serving size1 Capsule(s) Dosage formCapsule Servings per container100 Amounts shown are per serving.

Codonopsis

Interacts with
211 drugs
450 mg per serving

Codonopsis (often called 'dang shen') is a root long used in Traditional Chinese Medicine as a gentle energy and digestive tonic, frequently as a mild...

Codonopsis monograph & interactions

Other (inactive) ingredients: Gelatin, Water. These complete the product’s ingredient list but are not active constituents.

Interaction report

Codonopsis Root 450 mg by TerraVita Premium Collection Drug Interactions

Want to check YOUR meds against Codonopsis Root 450 mg?

Ask about interactions with your drugs in plain English — “Can I take it with lisinopril?” — and we find you the answer in seconds, ingredient by ingredient.

 Go to the checker
211Drugs
211 Moderate

Ingredients driving the most interactions

Codonopsis 211

Individual Drug Interactions

The ingredients in Codonopsis Root 450 mg interact with 211 drugs. Click any drug to see the details.

1 of the 1 ingredient in Codonopsis Root 450 mg interact with drugs. Each result below shows which ingredient is responsible. Codonopsis

Each ingredient & the kinds of drugs it affects

For each ingredient in Codonopsis Root 450 mg with known interactions, here are the types of medications it can affect. Open any type for the detail — or search your exact drug in the checker above.

Codonopsis3 drug types · 211 drugs

Abiraterone (Zytiga)

Theoretically, taking codonopsis root with abiraterone might reduce the levels and therapeutic effects of abiraterone.
Animal research in rats shows that intragastric administration of codonopsis root along with abiraterone every 2 days for 2 weeks seems to increase the clearance of abiraterone and reduce the overall exposure and time to maximum concentration. This interaction has not been reported in humans.

Likelihood Possible Evidence D
Anticoagulant/Antiplatelet Drugs

Theoretically, codonopsis liquor might increase the risk of bleeding when used with antiplatelet or anticoagulant drugs.
A small clinical study in adults with coronary heart disease shows that consuming Codonopsis pilosula liquor for 4 weeks inhibits platelet aggregation but does not affect tissue-type plasminogen activator (t-PA) or plasminogen activator inhibitor (PAI).

Likelihood Possible Evidence B
Antidiabetes Drugs

Theoretically, codonopsis might increase the risk of hypoglycemia when taken with antidiabetes drugs.
Laboratory and animal research suggest that codonopsis has antidiabetic effects.

Likelihood Possible Evidence D
Codonopsis full monograph & interactions
The maker

Brand information

Manufacturer and brand details for Codonopsis Root 450 mg, from the product label.

TerraVita Premium Collection

See all TerraVita Premium Collection products
Name
TerraVita Fine Whole Herbs
City
Brampton
State
Ontario
Pharmacist Counseling Corner

Codonopsis Root 450 mg by TerraVita Premium Collection: Common Questions

Does Codonopsis Root 450 mg by TerraVita Premium Collection interact with any medications?
Yes. Based on its ingredients, Codonopsis Root 450 mg has a known interaction with 211 medications. Use the checker to see how it interacts with a specific drug.
How can one product interact with so many drugs?
Codonopsis Root 450 mg contains a single active ingredient, and that one ingredient can interact with many different medications on its own. We check it against each medication and show the mechanism responsible.
Where does this information come from?
The product label data comes from the NIH Dietary Supplement Label Database (DSLD); the interaction data is built on the Natural Medicines database and reviewed by HelloPharmacist pharmacists.
What exactly is codonopsis and why is it in this product?
Codonopsis is a plant root used in traditional herbal medicine. This product contains 450 mg of codonopsis root per capsule. The evidence for what it actually does isn't established in our data, so we can't point to a specific health reason it's here — that's something to ask the maker or your healthcare provider about.
Can I take this if I'm pregnant or breastfeeding?
No, the safety data advises against codonopsis during pregnancy. Safety while breastfeeding is unknown, so avoid it unless your doctor advises otherwise. Talk with your doctor or pharmacist before taking this if you're pregnant, planning pregnancy, or breastfeeding.
What are the side effects?
At normal doses, codonopsis is generally well tolerated. At very large doses — 30 to 60 grams — it may cause chest pain, irregular heartbeat, throat pain, or loss of voice. Allergic reactions are possible, including rare severe ones like anaphylaxis. If you notice an allergic reaction or unusual symptoms, stop and contact your doctor.
Is one capsule a day safe?
Each capsule is 450 mg, which is a small amount. Codonopsis is generally considered well tolerated in traditional food-like amounts, but high-quality safety data are limited. If you have any health conditions or take medications, check with your doctor or pharmacist before starting.
Will this help with (asthma / cancer / colds / digestion / cholesterol)?
We have insufficient reliable evidence to rate codonopsis for any of those uses — that includes asthma, cancer, respiratory infections, indigestion, and high cholesterol. The science isn't there yet to say it works for them. Talk with your doctor if you're considering this for a specific health concern.
What's in the capsule besides the codonopsis root?
The capsule itself is made from gelatin and water. There are no fillers or binders listed.

Written and reviewed by the HelloPharmacist editorial staff. Our editorial policy

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Label information is sourced from the NIH Dietary Supplement Label Database and reflects the product version on file; always read your actual product label. This page is for education only and is not a substitute for professional medical advice. Confirm with your pharmacist or doctor before combining supplements and medications.

Codonopsis Root 450 mg label
Go deeper

The Full Monographs Behind Codonopsis Root 450 mg’s Ingredients

Every ingredient we hold a full HelloPharmacist monograph for — uses, evidence, safety, and the complete interaction list.

Herb & supplement monograph

Codonopsis

Interacts with 211 drugs

Codonopsis (often called 'dang shen') is a root long used in Traditional Chinese Medicine as a gentle energy and digestive tonic, frequently as a milder substitute for ginseng. Human researc...

Read the full Codonopsis monograph →
Sources

Sources & How We Checked

Codonopsis Root 450 mg's label data comes from the NIH Dietary Supplement Label Database; the ingredient interaction data is from the Natural Medicines database, reviewed by our pharmacists.

Content is written and reviewed by licensed HelloPharmacist pharmacists. See our data sources and editorial standards for how this information is built and checked.

The 5 references behind this product’s interaction data

Every citation that drives the interaction findings for this product’s ingredients, from the evidence-graded Natural Medicines (TRC Healthcare) database. Open an ingredient to browse its citations — links open the study on PubMed or the publisher’s site.

Codonopsis 5 references
  1. McGuffin M, Hobbs C, Upton R, Goldberg A, eds. American Herbal Products Association's Botanical Safety Handbook. Boca Raton, FL: CRC Press, LLC 1997.
  2. Xu, X., Wang, S. R., and Lin, Q. [Clinical and experimental study on codonopsis pilosula oral liquor in treating coronary heart disease with blood stasis]. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. 1995;15(7):398-400.
  3. Hur GY, Choi GS, Park HJ, Ye YM, Park HS. Anaphylactic shock induced by Codonopsis lanceolata, traditional Chinese medicine in a patient with allergic rhinitis. Allergy. 2008;63(10):1406-7.
  4. Zhang ZB, Ip SP, Cho WCS, et al. Herb-drug interactions between androgenic Chinese herbal medicines and androgen receptor antagonist on tumor growth: Studies on two xenograft prostate cancer animal models. Phytother Res. 2021.
  5. Jia W, Bi Q, Jiang S, et al. Hypoglycemic activity of Codonopsis pilosula (Franch.) Nannf. in vitro and in vivo and its chemical composition identification by UPLC-Triple-TOF-MS/MS. Food Funct 2022;13(5):2456-2464.

See these in context on the Codonopsis monograph →

Parts of this content are provided by the Therapeutic Research Center, LLC.

DISCLAIMER: Currently this does not check for drug-drug interactions. This is not an all-inclusive comprehensive list of potential interactions and is for informational purposes only. Not all interactions are known or well-reported in the scientific literature, and new interactions are continually being reported. Input is needed from a qualified healthcare provider including a pharmacist before starting any therapy. Application of clinical judgment is necessary.

© 2021 Therapeutic Research Center, LLC

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